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Search results 901 to 1000 out of 1211 for Aim2

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Type Details Score
Publication
21182089 | J:174655
First Author: Biswas A
Year: 2011
Journal: Eur J Immunol
Title: Negative regulation of Toll-like receptor signaling plays an essential role in homeostasis of the intestine.
Volume: 41
Issue: 1
Pages: 182-94
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22444631 | J:187333
First Author: Gross O
Year: 2012
Journal: Immunity
Title: Inflammasome activators induce interleukin-1α secretion via distinct pathways with differential requirement for the protease function of caspase-1.
Volume: 36
Issue: 3
Pages: 388-400
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Publication
15534227 | J:94732
First Author: Sato A
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Induction of antiviral immunity requires Toll-like receptor signaling in both stromal and dendritic cell compartments.
Volume: 101
Issue: 46
Pages: 16274-9
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Publication
29588315 | J:280022
First Author: Westerterp M
Year: 2018
Journal: Circulation
Title: Cholesterol Efflux Pathways Suppress Inflammasome Activation, NETosis, and Atherogenesis.
Volume: 138
Issue: 9
Pages: 898-912
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Publication
29937375 | J:266038
First Author: Tumurkhuu G
Year: 2018
Journal: Cell Metab
Title: Chlamydia pneumoniae Hijacks a Host Autoregulatory IL-1β Loop to Drive Foam Cell Formation and Accelerate Atherosclerosis.
Volume: 28
Issue: 3
Pages: 432-448.e4
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Publication
37865673 | J:342082
First Author: Harvest CK
Year: 2023
Journal: Nat Commun
Title: An innate granuloma eradicates an environmental pathogen using Gsdmd and Nos2.
Volume: 14
Issue: 1
Pages: 6686
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Publication
21282379 | J:176847
First Author: Bulua AC
Year: 2011
Journal: J Exp Med
Title: Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1-associated periodic syndrome (TRAPS).
Volume: 208
Issue: 3
Pages: 519-33
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Publication
37347796 | J:354250
First Author: Ngwaga T
Year: 2023
Journal: PLoS Pathog
Title: Effector-mediated subversion of proteasome activator (PA)28αβ enhances host defense against Legionella pneumophila under inflammatory and oxidative stress conditions.
Volume: 19
Issue: 6
Pages: e1011473
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Publication
31130511 | J:280247
First Author: Lee S
Year: 2019
Journal: Cell Host Microbe
Title: A Secreted Viral Nonstructural Protein Determines Intestinal Norovirus Pathogenesis.
Volume: 25
Issue: 6
Pages: 845-857.e5
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Publication
31967646 | J:289537
 
First Author: Gao Y
Year: 2020
Journal: J Exp Med
Title: Transcriptional profiling identifies caspase-1 as a T cell-intrinsic regulator of Th17 differentiation.
Volume: 217
Issue: 4
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Publication
35504893 | J:354863
First Author: Zhang Q
Year: 2022
Journal: Nat Commun
Title: TH17 cells promote CNS inflammation by sensing danger signals via Mincle.
Volume: 13
Issue: 1
Pages: 2406
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Publication
32428502 | J:296046
First Author: Tummers B
Year: 2020
Journal: Immunity
Title: Caspase-8-Dependent Inflammatory Responses Are Controlled by Its Adaptor, FADD, and Necroptosis.
Volume: 52
Issue: 6
Pages: 994-1006.e8
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Publication
34038731 | J:324648
First Author: Costa FRC
Year: 2021
Journal: Cell Rep
Title: NLRP1 acts as a negative regulator of Th17 cell programming in mice and humans with autoimmune diabetes.
Volume: 35
Issue: 8
Pages: 109176
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Publication
36146839 | J:343093
 
First Author: Li L
Year: 2022
Journal: Viruses
Title: Role of Caspases and Gasdermin A during HSV-1 Infection in Mice.
Volume: 14
Issue: 9
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Publication
19521510 | J:211458
First Author: Nogueira CV
Year: 2009
Journal: PLoS Pathog
Title: Rapid pathogen-induced apoptosis: a mechanism used by dendritic cells to limit intracellular replication of Legionella pneumophila.
Volume: 5
Issue: 6
Pages: e1000478
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Publication
16407889 | J:124226
First Author: Martinon F
Year: 2006
Journal: Nature
Title: Gout-associated uric acid crystals activate the NALP3 inflammasome.
Volume: 440
Issue: 7081
Pages: 237-41
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Publication
22723524 | J:189793
First Author: Trunk G
Year: 2012
Journal: J Immunol
Title: Innate instruction of CD4+ T cell immunity in respiratory bacterial infection.
Volume: 189
Issue: 2
Pages: 616-28
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Publication
22058415 | J:179683
First Author: Conforti-Andreoni C
Year: 2011
Journal: J Immunol
Title: Uric acid-driven Th17 differentiation requires inflammasome-derived IL-1 and IL-18.
Volume: 187
Issue: 11
Pages: 5842-50
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Publication
22802353 | J:189157
First Author: Willart MA
Year: 2012
Journal: J Exp Med
Title: Interleukin-1α controls allergic sensitization to inhaled house dust mite via the epithelial release of GM-CSF and IL-33.
Volume: 209
Issue: 8
Pages: 1505-17
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Publication
24084736 | J:203992
First Author: Brydges SD
Year: 2013
Journal: J Clin Invest
Title: Divergence of IL-1, IL-18, and cell death in NLRP3 inflammasomopathies.
Volume: 123
Issue: 11
Pages: 4695-705
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Publication
23090995 | J:191239
First Author: Drexler SK
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Tissue-specific opposing functions of the inflammasome adaptor ASC in the regulation of epithelial skin carcinogenesis.
Volume: 109
Issue: 45
Pages: 18384-9
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Publication
26536497 | J:252289
First Author: Oleszycka E
Year: 2016
Journal: FEBS J
Title: IL-1α and inflammasome-independent IL-1β promote neutrophil infiltration following alum vaccination.
Volume: 283
Issue: 1
Pages: 9-24
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Publication
26259586 | J:336475
First Author: Hägerbrand K
Year: 2015
Journal: J Immunol
Title: MyD88 Signaling Regulates Steady-State Migration of Intestinal CD103+ Dendritic Cells Independently of TNF-α and the Gut Microbiota.
Volume: 195
Issue: 6
Pages: 2888-99
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Publication
27732661 | J:253199
First Author: Ambite I
Year: 2016
Journal: PLoS Pathog
Title: Molecular Basis of Acute Cystitis Reveals Susceptibility Genes and Immunotherapeutic Targets.
Volume: 12
Issue: 10
Pages: e1005848
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Publication
16983331 | J:114842
First Author: Togbe D
Year: 2006
Journal: Lab Invest
Title: Nonredundant roles of TIRAP and MyD88 in airway response to endotoxin, independent of TRIF, IL-1 and IL-18 pathways.
Volume: 86
Issue: 11
Pages: 1126-35
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Publication
34233954 | J:320551
 
First Author: Alphonse MP
Year: 2021
Journal: Sci Transl Med
Title: Pan-caspase inhibition as a potential host-directed immunotherapy against MRSA and other bacterial skin infections.
Volume: 13
Issue: 601
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Publication
19454352 | J:360215
First Author: Hise AG
Year: 2009
Journal: Cell Host Microbe
Title: An essential role for the NLRP3 inflammasome in host defense against the human fungal pathogen Candida albicans.
Volume: 5
Issue: 5
Pages: 487-97
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Publication
26367131 | J:246842
First Author: Guo S
Year: 2015
Journal: PLoS Pathog
Title: The NLRP3 Inflammasome and IL-1β Accelerate Immunologically Mediated Pathology in Experimental Viral Fulminant Hepatitis.
Volume: 11
Issue: 9
Pages: e1005155
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Publication
27882934 | J:243066
 
First Author: Monnerat G
Year: 2016
Journal: Nat Commun
Title: Macrophage-dependent IL-1β production induces cardiac arrhythmias in diabetic mice.
Volume: 7
Pages: 13344
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Publication
32703941 | J:293007
First Author: Batista SJ
Year: 2020
Journal: Nat Commun
Title: Gasdermin-D-dependent IL-1α release from microglia promotes protective immunity during chronic Toxoplasma gondii infection.
Volume: 11
Issue: 1
Pages: 3687
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Publication
29146733 | J:270169
First Author: Marneros AG
Year: 2018
Journal: FASEB J
Title: Effects of chronically increased VEGF-A on the aging heart.
Volume: 32
Issue: 3
Pages: 1550-1565
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Publication
26203636 | J:227570
First Author: Milora KA
Year: 2015
Journal: J Invest Dermatol
Title: Unprocessed Interleukin-36α Regulates Psoriasis-Like Skin Inflammation in Cooperation With Interleukin-1.
Volume: 135
Issue: 12
Pages: 2992-3000
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Publication
26682985 | J:257985
First Author: Di Paolo NC
Year: 2015
Journal: Immunity
Title: Interdependence between Interleukin-1 and Tumor Necrosis Factor Regulates TNF-Dependent Control of Mycobacterium tuberculosis Infection.
Volume: 43
Issue: 6
Pages: 1125-36
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Publication
31533918 | J:282729
First Author: Koehn BH
Year: 2019
Journal: Blood
Title: Danger-associated extracellular ATP counters MDSC therapeutic efficacy in acute GVHD.
Volume: 134
Issue: 19
Pages: 1670-1682
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Publication
16565512 | J:107324
First Author: Chamberlain J
Year: 2006
Journal: Am J Pathol
Title: Interleukin-1beta and signaling of interleukin-1 in vascular wall and circulating cells modulates the extent of neointima formation in mice.
Volume: 168
Issue: 4
Pages: 1396-403
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Publication
31063608 | J:280822
First Author: de Carvalho RVH
Year: 2019
Journal: J Leukoc Biol
Title: Macrophage priming is dispensable for NLRP3 inflammasome activation and restriction of Leishmania amazonensis replication.
Volume: 106
Issue: 3
Pages: 631-640
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Publication
18250441 | J:131996
First Author: Andoh T
Year: 2008
Journal: J Immunol
Title: Protective effect of IL-18 on kainate- and IL-1 beta-induced cerebellar ataxia in mice.
Volume: 180
Issue: 4
Pages: 2322-8
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Publication
25198773 | J:221522
First Author: Place DE
Year: 2014
Journal: PLoS One
Title: Caspase-1-independent interleukin-1β is required for clearance of Bordetella pertussis infections and whole-cell vaccine-mediated immunity.
Volume: 9
Issue: 9
Pages: e107188
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Publication
22914048 | J:190231
First Author: Kono H
Year: 2012
Journal: J Immunol
Title: The IL-1-dependent sterile inflammatory response has a substantial caspase-1-independent component that requires cathepsin C.
Volume: 189
Issue: 7
Pages: 3734-40
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Publication
16272344 | J:119696
First Author: Noulin N
Year: 2005
Journal: J Immunol
Title: Both hemopoietic and resident cells are required for MyD88-dependent pulmonary inflammatory response to inhaled endotoxin.
Volume: 175
Issue: 10
Pages: 6861-9
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Publication
27007676 | J:296053
First Author: Qi X
Year: 2017
Journal: Mucosal Immunol
Title: Critical role of caspase-8-mediated IL-1 signaling in promoting Th2 responses during asthma pathogenesis.
Volume: 10
Issue: 1
Pages: 128-138
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Publication
25295542 | J:217703
First Author: Wegiel B
Year: 2014
Journal: J Clin Invest
Title: Macrophages sense and kill bacteria through carbon monoxide-dependent inflammasome activation.
Volume: 124
Issue: 11
Pages: 4926-40
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Publication
23964013 | J:205861
First Author: Allam R
Year: 2013
Journal: Eur J Immunol
Title: Histones trigger sterile inflammation by activating the NLRP3 inflammasome.
Volume: 43
Issue: 12
Pages: 3336-42
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Publication
16984919 | J:117251
First Author: Amer A
Year: 2006
Journal: J Biol Chem
Title: Regulation of Legionella phagosome maturation and infection through flagellin and host Ipaf.
Volume: 281
Issue: 46
Pages: 35217-23
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Publication
17004992 | J:135842
First Author: Albiger B
Year: 2007
Journal: Cell Microbiol
Title: Toll-like receptor 9 acts at an early stage in host defence against pneumococcal infection.
Volume: 9
Issue: 3
Pages: 633-44
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Publication
21708993 | J:175707
First Author: Kordes M
Year: 2011
Journal: Infect Immun
Title: Caspase-1 activation of interleukin-1β (IL-1β) and IL-18 is dispensable for induction of experimental cerebral malaria.
Volume: 79
Issue: 9
Pages: 3633-41
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Publication
18322222 | J:132928
First Author: Zwaferink H
Year: 2008
Journal: J Immunol
Title: IFN-beta increases listeriolysin O-induced membrane permeabilization and death of macrophages.
Volume: 180
Issue: 6
Pages: 4116-23
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Publication
17360653 | J:125936
First Author: Miggin SM
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: NF-kappaB activation by the Toll-IL-1 receptor domain protein MyD88 adapter-like is regulated by caspase-1.
Volume: 104
Issue: 9
Pages: 3372-7
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Publication
39340778 | J:358149
First Author: Pizzuto M
Year: 2024
Journal: Cell Rep
Title: Ornithine lipid is a partial TLR4 agonist and NLRP3 activator.
Volume: 43
Issue: 10
Pages: 114788
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Publication
18493980 | J:136368
First Author: Kang TJ
Year: 2008
Journal: Eur J Immunol
Title: Bacillus anthracis spores and lethal toxin induce IL-1beta via functionally distinct signaling pathways.
Volume: 38
Issue: 6
Pages: 1574-84
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Publication
33305736 | J:316381
   
First Author: Malsy J
Year: 2020
Journal: Elife
Title: Distinct effects of complement and of NLRP3- and non-NLRP3 inflammasomes for choroidal neovascularization.
Volume: 9
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Publication
31420376 | J:282180
First Author: Volk JK
Year: 2019
Journal: J Exp Med
Title: The Nlrp6 inflammasome is not required for baseline colonic inner mucus layer formation or function.
Volume: 216
Issue: 11
Pages: 2602-2618
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Publication
29491424 | J:262639
First Author: Lee BL
Year: 2018
Journal: Sci Rep
Title: ASC- and caspase-8-dependent apoptotic pathway diverges from the NLRC4 inflammasome in macrophages.
Volume: 8
Issue: 1
Pages: 3788
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Publication
36417874 | J:332004
First Author: Oh C
Year: 2022
Journal: Cell Rep
Title: Neutrophil inflammasomes sense the subcellular delivery route of translocated bacterial effectors and toxins.
Volume: 41
Issue: 8
Pages: 111688
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Publication
38326859 | J:350706
First Author: Daily KP
Year: 2024
Journal: Alzheimers Res Ther
Title: DNA hypomethylation promotes the expression of CASPASE-4 which exacerbates inflammation and amyloid-β deposition in Alzheimer's disease.
Volume: 16
Issue: 1
Pages: 29
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Publication
22046355 | J:178074
First Author: Lichtnekert J
Year: 2011
Journal: PLoS One
Title: Anti-GBM glomerulonephritis involves IL-1 but is independent of NLRP3/ASC inflammasome-mediated activation of caspase-1.
Volume: 6
Issue: 10
Pages: e26778
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Publication
25405768 | J:225298
First Author: Eltom S
Year: 2014
Journal: PLoS One
Title: Role of the inflammasome-caspase1/11-IL-1/18 axis in cigarette smoke driven airway inflammation: an insight into the pathogenesis of COPD.
Volume: 9
Issue: 11
Pages: e112829
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19596996 | J:151581
First Author: Serbina NV
Year: 2009
Journal: J Immunol
Title: Selective expansion of the monocytic lineage directed by bacterial infection.
Volume: 183
Issue: 3
Pages: 1900-10
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Publication
28410991 | J:255168
First Author: Rauch I
Year: 2017
Journal: Immunity
Title: NAIP-NLRC4 Inflammasomes Coordinate Intestinal Epithelial Cell Expulsion with Eicosanoid and IL-18 Release via Activation of Caspase-1 and -8.
Volume: 46
Issue: 4
Pages: 649-659
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30266768 | J:267678
First Author: Sun Y
Year: 2018
Journal: J Immunol
Title: Neutrophil Caspase-11 Is Required for Cleavage of Caspase-1 and Secretion of IL-1β in Aspergillus fumigatus Infection.
Volume: 201
Issue: 9
Pages: 2767-2775
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Publication
26100631 | J:224602
First Author: Antonopoulos C
Year: 2015
Journal: J Biol Chem
Title: Caspase-8 as an Effector and Regulator of NLRP3 Inflammasome Signaling.
Volume: 290
Issue: 33
Pages: 20167-84
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Publication
38000038 | J:343254
First Author: Doglio MG
Year: 2023
Journal: Sci Immunol
Title: Myeloid OTULIN deficiency couples RIPK3-dependent cell death to Nlrp3 inflammasome activation and IL-1β secretion.
Volume: 8
Issue: 89
Pages: eadf4404
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Publication
24715728 | J:208845
First Author: Pilla DM
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Guanylate binding proteins promote caspase-11-dependent pyroptosis in response to cytoplasmic LPS.
Volume: 111
Issue: 16
Pages: 6046-51
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Publication
22235111 | J:183298
First Author: Hanley PJ
Year: 2012
Journal: J Biol Chem
Title: Transient P2X7 receptor activation triggers macrophage death independent of Toll-like receptors 2 and 4, caspase-1, and pannexin-1 proteins.
Volume: 287
Issue: 13
Pages: 10650-63
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Publication
24739961 | J:210626
First Author: Meunier E
Year: 2014
Journal: Nature
Title: Caspase-11 activation requires lysis of pathogen-containing vacuoles by IFN-induced GTPases.
Volume: 509
Issue: 7500
Pages: 366-70
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Publication
31251782 | J:324736
First Author: Gonçalves AV
Year: 2019
Journal: PLoS Pathog
Title: Gasdermin-D and Caspase-7 are the key Caspase-1/8 substrates downstream of the NAIP5/NLRC4 inflammasome required for restriction of Legionella pneumophila.
Volume: 15
Issue: 6
Pages: e1007886
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Publication
27911804 | J:263129
First Author: Van Gorp H
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Familial Mediterranean fever mutations lift the obligatory requirement for microtubules in Pyrin inflammasome activation.
Volume: 113
Issue: 50
Pages: 14384-14389
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Publication
24078693 | J:206238
First Author: Antonopoulos C
Year: 2013
Journal: J Immunol
Title: Proapoptotic chemotherapeutic drugs induce noncanonical processing and release of IL-1β via caspase-8 in dendritic cells.
Volume: 191
Issue: 9
Pages: 4789-803
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Publication
29520027 | J:260737
First Author: Chu LH
Year: 2018
Journal: Nat Commun
Title: The oxidized phospholipid oxPAPC protects from septic shock by targeting the non-canonical inflammasome in macrophages.
Volume: 9
Issue: 1
Pages: 996
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Publication
25815426 | J:222974
First Author: Lee DJ
Year: 2015
Journal: J Invest Dermatol
Title: Regulation and Function of the Caspase-1 in an Inflammatory Microenvironment.
Volume: 135
Issue: 8
Pages: 2012-2020
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29045901 | J:259375
First Author: Zanoni I
Year: 2017
Journal: Immunity
Title: By Capturing Inflammatory Lipids Released from Dying Cells, the Receptor CD14 Induces Inflammasome-Dependent Phagocyte Hyperactivation.
Volume: 47
Issue: 4
Pages: 697-709.e3
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Publication
25473914 | J:227950
First Author: Hirano Y
Year: 2014
Journal: Nat Med
Title: IL-18 is not therapeutic for neovascular age-related macular degeneration.
Volume: 20
Issue: 12
Pages: 1372-5
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19164858 | J:146148
First Author: Imaeda AB
Year: 2009
Journal: J Clin Invest
Title: Acetaminophen-induced hepatotoxicity in mice is dependent on Tlr9 and the Nalp3 inflammasome.
Volume: 119
Issue: 2
Pages: 305-14
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28951422 | J:250772
First Author: Skyberg JA
Year: 2017
Journal: J Leukoc Biol
Title: Hematopoietic MyD88 and IL-18 are essential for IFN-γ-dependent restriction of type A Francisella tularensis infection.
Volume: 102
Issue: 6
Pages: 1441-1450
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17878377 | J:152337
First Author: Pedra JH
Year: 2007
Journal: J Immunol
Title: ASC/PYCARD and caspase-1 regulate the IL-18/IFN-gamma axis during Anaplasma phagocytophilum infection.
Volume: 179
Issue: 7
Pages: 4783-91
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29130929 | J:273908
First Author: McGeough MD
Year: 2017
Journal: J Clin Invest
Title: TNF regulates transcription of NLRP3 inflammasome components and inflammatory molecules in cryopyrinopathies.
Volume: 127
Issue: 12
Pages: 4488-4497
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Publication
28404595 | J:242007
First Author: Freeman L
Year: 2017
Journal: J Exp Med
Title: NLR members NLRC4 and NLRP3 mediate sterile inflammasome activation in microglia and astrocytes.
Volume: 214
Issue: 5
Pages: 1351-1370
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Publication
32400277 | J:313050
First Author: Ko MS
Year: 2021
Journal: Autophagy
Title: Mitophagy deficiency increases NLRP3 to induce brown fat dysfunction in mice.
Volume: 17
Issue: 5
Pages: 1205-1221
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34315884 | J:321273
First Author: Mayes-Hopfinger L
Year: 2021
Journal: Nat Commun
Title: Chloride sensing by WNK1 regulates NLRP3 inflammasome activation and pyroptosis.
Volume: 12
Issue: 1
Pages: 4546
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Publication
33097533 | J:313496
 
First Author: Qu Z
Year: 2020
Journal: Sci Adv
Title: Mycobacterial EST12 activates a RACK1-NLRP3-gasdermin D pyroptosis-IL-1β immune pathway.
Volume: 6
Issue: 43
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Publication
36367942 | J:359970
First Author: Wu YH
Year: 2022
Journal: Sci Adv
Title: Caspase-8 inactivation drives autophagy-dependent inflammasome activation in myeloid cells.
Volume: 8
Issue: 45
Pages: eabn9912
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Publication
30735126 | J:275972
   
First Author: Dosch M
Year: 2019
Journal: Elife
Title: Connexin-43-dependent ATP release mediates macrophage activation during sepsis.
Volume: 8
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Publication
29937272 | J:277094
First Author: Kang R
Year: 2018
Journal: Cell Host Microbe
Title: Lipid Peroxidation Drives Gasdermin D-Mediated Pyroptosis in Lethal Polymicrobial Sepsis.
Volume: 24
Issue: 1
Pages: 97-108.e4
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Publication
39571575 | J:359877
First Author: Wang Y
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