|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 901 to 1000 out of 1476 for Ccl2

0.023s
Type Details Score
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Flavell RA
Year: 2007
Journal: MGI Direct Data Submission
Title: Generation of Ccl2 transgenic mice
Publication  
First Author: Bray JG
Year: 2013
Journal: Neuropharmacology
Title: Synaptic plasticity in the hippocampus shows resistance to acute ethanol exposure in transgenic mice with astrocyte-targeted enhanced CCL2 expression.
Volume: 67
Pages: 115-25
Publication
First Author: Ma Z
Year: 2019
Journal: Cell Rep
Title: Bone Marrow Mesenchymal Stromal Cell-Derived Periostin Promotes B-ALL Progression by Modulating CCL2 in Leukemia Cells.
Volume: 26
Issue: 6
Pages: 1533-1543.e4
Publication
First Author: Greenblatt MB
Year: 2012
Journal: Am J Pathol
Title: Interspecies comparison of human and murine scleroderma reveals IL-13 and CCL2 as disease subset-specific targets.
Volume: 180
Issue: 3
Pages: 1080-94
Publication
First Author: Tomida D
Year: 2011
Journal: Invest Ophthalmol Vis Sci
Title: Suppression of choroidal neovascularization and quantitative and qualitative inhibition of VEGF and CCL2 by heparin.
Volume: 52
Issue: 6
Pages: 3193-9
Publication
First Author: Maus UA
Year: 2005
Journal: Am J Physiol Lung Cell Mol Physiol
Title: CCR2-positive monocytes recruited to inflamed lungs downregulate local CCL2 chemokine levels.
Volume: 288
Issue: 2
Pages: L350-8
Publication
First Author: Chen H
Year: 2017
Journal: Genes Brain Behav
Title: Midkine in the mouse ventral tegmental area limits ethanol intake and Ccl2 gene expression.
Volume: 16
Issue: 7
Pages: 699-708
Publication
First Author: Weng J
Year: 2024
Journal: Cancer Res
Title: Repolarization of Immunosuppressive Macrophages by Targeting SLAMF7-Regulated CCL2 Signaling Sensitizes Hepatocellular Carcinoma to Immunotherapy.
Volume: 84
Issue: 11
Pages: 1817-1833
Publication
First Author: Toft-Hansen H
Year: 2006
Journal: J Immunol
Title: Metalloproteinases control brain inflammation induced by pertussis toxin in mice overexpressing the chemokine CCL2 in the central nervous system.
Volume: 177
Issue: 10
Pages: 7242-9
Publication
First Author: Long KB
Year: 2016
Journal: Cancer Discov
Title: IFNγ and CCL2 Cooperate to Redirect Tumor-Infiltrating Monocytes to Degrade Fibrosis and Enhance Chemotherapy Efficacy in Pancreatic Carcinoma.
Volume: 6
Issue: 4
Pages: 400-413
Publication
First Author: Ahmad R
Year: 2018
Journal: J Immunol
Title: The Synergy between Palmitate and TNF-α for CCL2 Production Is Dependent on the TRIF/IRF3 Pathway: Implications for Metabolic Inflammation.
Volume: 200
Issue: 10
Pages: 3599-3611
GO Term
GO Term
GO Term
Publication
First Author: Liu F
Year: 2021
Journal: J Neurochem
Title: Wolfberry-derived zeaxanthin dipalmitate delays retinal degeneration in a mouse model of retinitis pigmentosa through modulating STAT3, CCL2 and MAPK pathways.
Volume: 158
Issue: 5
Pages: 1131-1150
Publication
First Author: Falkenham A
Year: 2013
Journal: Am J Pathol
Title: Early fibroblast progenitor cell migration to the AngII-exposed myocardium is not CXCL12 or CCL2 dependent as previously thought.
Volume: 183
Issue: 2
Pages: 459-69
Publication
First Author: Martin AP
Year: 2008
Journal: Diabetes
Title: Increased expression of CCL2 in insulin-producing cells of transgenic mice promotes mobilization of myeloid cells from the bone marrow, marked insulitis, and diabetes.
Volume: 57
Issue: 11
Pages: 3025-33
Publication
First Author: Bennett JL
Year: 2003
Journal: J Neurovirol
Title: CCL2 transgene expression in the central nervous system directs diffuse infiltration of CD45(high)CD11b(+) monocytes and enhanced Theiler's murine encephalomyelitis virus-induced demyelinating disease.
Volume: 9
Issue: 6
Pages: 623-36
Publication  
First Author: Morioka N
Year: 2016
Journal: Mol Cell Neurosci
Title: Downregulation of the spinal dorsal horn clock gene Per1 expression leads to mechanical hypersensitivity via c-jun N-terminal kinase and CCL2 production in mice.
Volume: 72
Pages: 72-83
Publication
First Author: Kubo F
Year: 2019
Journal: Respir Res
Title: Loss of the adhesion G-protein coupled receptor ADGRF5 in mice induces airway inflammation and the expression of CCL2 in lung endothelial cells.
Volume: 20
Issue: 1
Pages: 11
Publication  
First Author: Wilkerson JL
Year: 2022
Journal: Brain Res
Title: Peripherally administered cannabinoid receptor 2 (CB2R) agonists lose anti-allodynic effects in TRPV1 knockout mice, while intrathecal administration leads to anti-allodynia and reduced GFAP, CCL2 and TRPV1 expression in the dorsal spinal cord and DRG.
Volume: 1774
Pages: 147721
Publication
First Author: Soria G
Year: 2008
Journal: Cancer Lett
Title: The inflammatory chemokines CCL2 and CCL5 in breast cancer.
Volume: 267
Issue: 2
Pages: 271-85
Allele
Name: transgene insertion, Pappachan Kolattukudy
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Publication
First Author: Zhou L
Year: 2006
Journal: Circ Res
Title: Monocyte chemoattractant protein-1 induces a novel transcription factor that causes cardiac myocyte apoptosis and ventricular dysfunction.
Volume: 98
Issue: 9
Pages: 1177-85
Allele
Name: transgene insertion JE95, Richard Ransohoff
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Publication
First Author: Kolattukudy PE
Year: 1998
Journal: Am J Pathol
Title: Myocarditis induced by targeted expression of the MCP-1 gene in murine cardiac muscle.
Volume: 152
Issue: 1
Pages: 101-11
GO Term
GO Term
Strain
Attribute String: congenic, mutant strain, transgenic
GO Term
GO Term
GO Term
Allele
Name: transgene insertion 1, Kazunori Onoe
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion 1, Eric G Pamer
Allele Type: Transgenic
Attribute String: Epitope tag, Reporter
Strain
Attribute String: mutant strain, coisogenic, transgenic
Publication
First Author: Huang D
Year: 2002
Journal: J Neurosci
Title: Pertussis toxin-induced reversible encephalopathy dependent on monocyte chemoattractant protein-1 overexpression in mice.
Volume: 22
Issue: 24
Pages: 10633-42
Publication
First Author: Moldovan NI
Year: 2000
Journal: Circ Res
Title: Contribution of monocytes/macrophages to compensatory neovascularization: the drilling of metalloelastase-positive tunnels in ischemic myocardium.
Volume: 87
Issue: 5
Pages: 378-84
Strain
Attribute String: congenic, mutant strain, transgenic
Publication
First Author: Gunning P
Year: 1987
Journal: Proc Natl Acad Sci U S A
Title: A human beta-actin expression vector system directs high-level accumulation of antisense transcripts.
Volume: 84
Issue: 14
Pages: 4831-5
Publication
First Author: Mizumoto N
Year: 2001
Journal: Immunobiology
Title: Enhanced contact hypersensitivity in human monocyte chemoattractant protein-1 transgenic mouse.
Volume: 204
Issue: 4
Pages: 477-93
Publication
First Author: Ato M
Year: 2000
Journal: Immunobiology
Title: Delayed clearance of zymosan-induced granuloma and depressed phagocytosis of macrophages with concomitant up-regulated kinase activities of Src-family in a human monocyte chemoattractant protein-1 transgenic mouse.
Volume: 201
Issue: 3-4
Pages: 432-49
HT Experiment  
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
Publication
First Author: Llanos S
Year: 2016
Journal: Cancer Cell
Title: Senescence and Cancer: In the Name of Immunosuppression.
Volume: 30
Issue: 4
Pages: 507-508
Publication
First Author: Dhandapani PK
Year: 2019
Journal: Sci Rep
Title: Hyperoxia but not AOX expression mitigates pathological cardiac remodeling in a mouse model of inflammatory cardiomyopathy.
Volume: 9
Issue: 1
Pages: 12741
Publication  
First Author: Keil M
Year: 2016
Journal: J Neuroimmunol
Title: General control non-derepressible 2 (GCN2) in T cells controls disease progression of autoimmune neuroinflammation.
Volume: 297
Pages: 117-26
Publication
First Author: Thapa M
Year: 2008
Journal: J Virol
Title: Herpes simplex virus type 2-induced mortality following genital infection is blocked by anti-tumor necrosis factor alpha antibody in CXCL10-deficient mice.
Volume: 82
Issue: 20
Pages: 10295-301
Publication  
First Author: Li X
Year: 2022
Journal: Int Immunopharmacol
Title: CCL2-mediated monocytes regulate immune checkpoint blockade resistance in pancreatic cancer.
Volume: 106
Pages: 108598
Publication
First Author: Palomino DC
Year: 2015
Journal: Einstein (Sao Paulo)
Title: Chemokines and immunity.
Volume: 13
Issue: 3
Pages: 469-73
Protein Domain
Type: Family
Description: The chemokine family is divided into four classes based on the number and spacing of their conserved cysteines: 2 Cys residues may be adjacent (the CC family), or separated by an intervening residue (the CXC family), or have only one of the first two Cys residues (C chemokines), or contain both cysteines separated by three intervening residues (CX3C chemokines).This entry includes beta-chemokines (CC chemokines), in addition to gamma (C chemokines) and delta-chemokines (CX3C chemokines). CC chemokines stimulate mainly monocytes, but also basophils, eosinophils, T-lymphocytes, and natural killer (NK) cells. C-C motif chemokine 2 (CCL2) stimulates chemotaxis of monocytes and several cellular events associated with chemotaxis. Two other chemokines structurally related to CCL2 are CCL8 (MCP-2) and CCL7 (MCP-3) [].The C chemokine subfamily is composed of two members, XC chemokine ligand 1 (XCL1), also known as lymphotactin or SCM-1 alpha, and XC chemokine ligand 2 (XCL2), also known as SCM-1 beta []. The cognate receptor for these chemokines is XCR1 []. The only CX3C chemokine identified to date is CX3C chemokine ligand 1 (CX3CL1), also known as fractalkine or neurotactin. With its unique CX3CR1 receptor [], it is involved in adherence to the endothelium of the inflammatory monocyte population [].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression  
Probe: MGI:4884850
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691619
Pattern: Widespread
Stage: TS19
Assay Id: MGI:4945757
Age: embryonic day 11.5
Image: g01454 E11.5
Specimen Label: g01454 E11.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4884850
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691623
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945757
Age: embryonic day 15.5
Image: g01454 E15.5
Specimen Label: g01454 E15.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4884850
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284223
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945757
Age: embryonic day 15.5
Image: g01454 E15.5
Specimen Label: g01454 E15.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4884850
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267828
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945757
Age: postnatal day 7
Image: g01454 P7
Specimen Label: g01454 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4884850
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267828
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945757
Age: postnatal day 42
Image: g01454 Adult
Specimen Label: g01454 Adult
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:4884850
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697419
Pattern: Widespread
Stage: TS19
Assay Id: MGI:4945757
Age: embryonic day 11.5
Image: g01454 E11.5
Specimen Label: g01454 E11.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4884850
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697423
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945757
Age: embryonic day 15.5
Image: g01454 E15.5
Specimen Label: g01454 E15.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4884850
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697428
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945757
Age: postnatal day 7
Image: g01454 P7
Specimen Label: g01454 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4884850
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697428
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945757
Age: postnatal day 42
Image: g01454 Adult
Specimen Label: g01454 Adult
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:4884850
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4945757
Age: embryonic day 15.5
Image: g01454 E15.5
Specimen Label: g01454 E15.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4884850
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945757
Age: postnatal day 7
Image: g01454 P7
Specimen Label: g01454 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4884850
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945757
Age: postnatal day 42
Image: g01454 Adult
Specimen Label: g01454 Adult
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:4884850
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1753623
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945757
Age: embryonic day 15.5
Image: g01454 E15.5
Specimen Label: g01454 E15.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4884850
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1753628
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945757
Age: postnatal day 7
Image: g01454 P7
Specimen Label: g01454 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4884850
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1753628
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945757
Age: postnatal day 42
Image: g01454 Adult
Specimen Label: g01454 Adult
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:4884850
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778723
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945757
Age: embryonic day 15.5
Image: g01454 E15.5
Specimen Label: g01454 E15.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4884850
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945757
Age: postnatal day 7
Image: g01454 P7
Specimen Label: g01454 P7
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:4884850
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945757
Age: postnatal day 42
Image: g01454 Adult
Note: Expression was region specific and scattered.
Specimen Label: g01454 Adult
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:4884850
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945757
Age: postnatal day 7
Image: g01454 P7
Specimen Label: g01454 P7
Detected: true
Specimen Num: 3