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Search results 901 to 1000 out of 1187 for E2f1

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Type Details Score
Publication
32290105 | J:282558
 
First Author: Collin GB
Year: 2020
Journal: Cells
Title: Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss.
Volume: 9
Issue: 4
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Publication
21731673 | J:174767
First Author: Tang F
Year: 2011
Journal: PLoS One
Title: Deterministic and stochastic allele specific gene expression in single mouse blastomeres.
Volume: 6
Issue: 6
Pages: e21208
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Publication
- | J:342607
       
First Author: Birgit Meldal and Sandra Orchard (1). (1) European Bioinformatics Institute (EBI), Hinxton, Cambridgeshire, United Kingdom
Year: 2023
Title: Manual transfer of experimentally-verified manual GO annotation data to homologous complexes by curator judgment of sequence, composition and function similarity
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Publication
22988430 | J:190636
 
First Author: Wiese CB
Year: 2012
Journal: Front Neurosci
Title: A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.
Volume: 6
Pages: 130
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Publication
20412781 | J:140465
First Author: Guo G
Year: 2010
Journal: Dev Cell
Title: Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.
Volume: 18
Issue: 4
Pages: 675-85
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Publication
20059953 | J:156017
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
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Publication
- | J:345476
       
First Author: Haiming Tang, Dustin Ebert, Matthias Blum, Robert Finn, Paul Thomas
Year: 2023
Title: TreeGrafter-generated GO annotations
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Publication
15618518 | J:91257
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
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Publication
24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Protein
Q61501
Organism: Mus musculus/domesticus
Length: 430  
Fragment?: false
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Protein
Q9CYB4
Organism: Mus musculus/domesticus
Length: 385  
Fragment?: false
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HT Experiment
E-GEOD-67989 | Genome-wide analysis of E2F1 dependent gene expression in mouse testicular tissue
Series Id: GSE67989
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
12724423 | J:83303
First Author: Scheijen B
Year: 2003
Journal: Mol Cell Biol
Title: Constitutive E2F1 overexpression delays endochondral bone formation by inhibiting chondrocyte differentiation.
Volume: 23
Issue: 10
Pages: 3656-68
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Publication
12080472 | J:77720
First Author: Wunderlich M
Year: 2002
Journal: Oncogene
Title: Mdm2 inhibition of p53 induces E2F1 transactivation via p21.
Volume: 21
Issue: 28
Pages: 4414-21
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Publication
29235459 | J:257672
First Author: Gnanasundram SV
Year: 2017
Journal: Nat Commun
Title: PI3Kδ activates E2F1 synthesis in response to mRNA translation stress.
Volume: 8
Issue: 1
Pages: 2103
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Publication
20805247 | J:173817
First Author: Taura M
Year: 2011
Journal: Nucleic Acids Res
Title: MEF/ELF4 transactivation by E2F1 is inhibited by p53.
Volume: 39
Issue: 1
Pages: 76-88
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Publication
9546428 | J:46535
First Author: Pierce AM
Year: 1998
Journal: Oncogene
Title: Deregulated expression of E2F1 induces hyperplasia and cooperates with ras in skin tumor development.
Volume: 16
Issue: 10
Pages: 1267-76
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Publication
8336704 | J:279973
First Author: Zacksenhaus E
Year: 1993
Journal: Mol Cell Biol
Title: A bipartite nuclear localization signal in the retinoblastoma gene product and its importance for biological activity.
Volume: 13
Issue: 8
Pages: 4588-99
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Publication
16914062 | J:114896
 
First Author: Fedele M
Year: 2006
Journal: Cell Div
Title: E2F1 activation is responsible for pituitary adenomas induced by HMGA2 gene overexpression.
Volume: 1
Pages: 17
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Publication
16892051 | J:178276
First Author: Wang C
Year: 2006
Journal: Nat Cell Biol
Title: Interactions between E2F1 and SirT1 regulate apoptotic response to DNA damage.
Volume: 8
Issue: 9
Pages: 1025-31
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Publication
19837943 | J:154681
First Author: Zhou C
Year: 2009
Journal: Mol Endocrinol
Title: E2F1 induces pituitary tumor transforming gene (PTTG1) expression in human pituitary tumors.
Volume: 23
Issue: 12
Pages: 2000-12
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Publication
33947907 | J:306067
First Author: Swiatnicki MR
Year: 2021
Journal: Sci Rep
Title: Metastasis is altered through multiple processes regulated by the E2F1 transcription factor.
Volume: 11
Issue: 1
Pages: 9502
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Publication
14739777 | -
First Author: Wunderlich M
Year: 2004
Journal: Cell Cycle
Title: MdmX represses E2F1 transactivation.
Volume: 3
Issue: 4
Pages: 472-8
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Publication
21625432 | J:172724
First Author: Palomer X
Year: 2011
Journal: PLoS One
Title: The interplay between NF-kappaB and E2F1 coordinately regulates inflammation and metabolism in human cardiac cells.
Volume: 6
Issue: 5
Pages: e19724
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Publication
17483310 | J:121307
First Author: Olson MV
Year: 2007
Journal: Cancer Res
Title: Transgenic E2F1 expression in the mouse brain induces a human-like bimodal pattern of tumors.
Volume: 67
Issue: 9
Pages: 4005-9
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Publication
12077144 | J:78775
First Author: Blais A
Year: 2002
Journal: J Biol Chem
Title: Regulation of the human cyclin-dependent kinase inhibitor p18INK4c by the transcription factors E2F1 and Sp1.
Volume: 277
Issue: 35
Pages: 31679-93
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Publication
16254079 | J:159155
First Author: Zhang Y
Year: 2005
Journal: Nucleic Acids Res
Title: The ErbB3 binding protein Ebp1 interacts with Sin3A to repress E2F1 and AR-mediated transcription.
Volume: 33
Issue: 18
Pages: 6024-33
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Transgene
MGI:2677032 | Tg(KRT5-E2F1)2Dgj
Type: transgene
Organism: mouse, laboratory
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Interaction Experiment
Fedele M (2006)
Description: HMGA2 induces pituitary tumorigenesis by enhancing E2F1 activity.
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Publication
15209999 | J:110247
First Author: Matsumoto N
Year: 2004
Journal: Oral Microbiol Immunol
Title: Role of gene E2f1 in susceptibility to bacterial adherence of oral streptococci to tooth surfaces in mice.
Volume: 19
Issue: 4
Pages: 270-6
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Publication
23744542 | J:200011
First Author: Mans DA
Year: 2013
Journal: J Pathol
Title: Regulation of E2F1 by the von Hippel-Lindau tumour suppressor protein predicts survival in renal cell cancer patients.
Volume: 231
Issue: 1
Pages: 117-29
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Publication
24038073 | J:320512
First Author: Wang B
Year: 2014
Journal: Hepatology
Title: Reciprocal regulation of microRNA-122 and c-Myc in hepatocellular cancer: role of E2F1 and transcription factor dimerization partner 2.
Volume: 59
Issue: 2
Pages: 555-66
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Publication
28702328 | J:256322
First Author: Haim Y
Year: 2017
Journal: Mol Metab
Title: ASK1 (MAP3K5) is transcriptionally upregulated by E2F1 in adipose tissue in obesity, molecularly defining a human dys-metabolic obese phenotype.
Volume: 6
Issue: 7
Pages: 725-736
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Publication
27470638 | J:251187
First Author: Gurha P
Year: 2016
Journal: Circ Res
Title: Knockdown of Plakophilin 2 Downregulates miR-184 Through CpG Hypermethylation and Suppression of the E2F1 Pathway and Leads to Enhanced Adipogenesis In Vitro.
Volume: 119
Issue: 6
Pages: 731-50
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Interaction Experiment
Zhou F (2008)
Description: The association of GSK3 beta with E2F1 facilitates nerve growth factor-induced neural cell differentiation.
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Interaction Experiment
Hong W (2011)
Description: Epigenetic involvement of Alien/ESET complex in thyroid hormone-mediated repression of E2F1 gene expression and cell proliferation.
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GXD Expression
GXD Expression
 
Probe: MGI:29437
Assay Type: RNA in situ
Annotation Date: 2020-05-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3578426
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:6415734
Age: embryonic day 18.5
Note: Expressed in the core of the villus (lamina propria) and the adjacent epithelia, same as the E2f1 expression.
Specimen Label: 4 left
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:29437
Assay Type: RNA in situ
Annotation Date: 2020-05-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3578426
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:6415734
Age: embryonic day 18.5
Note: Expressed in the core of the villus (lamina propria) and the adjacent epithelia, same as the E2f1 expression.
Specimen Label: 4 right
Detected: true
Specimen Num: 2
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Allele
E2f1<em1Smoc> | MGI:7645594
Name: E2F transcription factor 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Interaction Experiment
Swarnalatha M (2013)
Description: Promoter occupancy of MLL1 histone methyltransferase seems to specify the proliferative and apoptotic functions of E2F1 in a tumour microenvironment.
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Publication
20940255 | -
First Author: Pickard A
Year: 2010
Journal: J Cell Sci
Title: Acetylation of Rb by PCAF is required for nuclear localization and keratinocyte differentiation.
Volume: 123
Issue: Pt 21
Pages: 3718-26
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Publication
21653699 | -
First Author: Cartier J
Year: 2011
Journal: J Biol Chem
Title: Cellular inhibitor of apoptosis protein-1 (cIAP1) can regulate E2F1 transcription factor-mediated control of cyclin transcription.
Volume: 286
Issue: 30
Pages: 26406-17
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Strain
MGI:6428554 | C57BL/6J-E2f1<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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HT Experiment
E-GEOD-71380 | E2f regulation of gene expression in the liver [1 mo]
Series Id: GSE71380
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
10888886 | -
First Author: Robertson KD
Year: 2000
Journal: Nat Genet
Title: DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters.
Volume: 25
Issue: 3
Pages: 338-42
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Publication
9364211 | -
First Author: Johnson DG
Year: 1997
Journal: Mol Carcinog
Title: High-affinity binding of the cell cycle-regulated transcription factors E2F1 and E2F4 to benzo[a]pyrene diol epoxide-DNA adducts.
Volume: 20
Issue: 2
Pages: 216-23
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Publication
18367454 | -
First Author: Zhou F
Year: 2008
Journal: J Biol Chem
Title: The association of GSK3 beta with E2F1 facilitates nerve growth factor-induced neural cell differentiation.
Volume: 283
Issue: 21
Pages: 14506-15
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Allele
Tg(Alb-E2F1)8Sst | MGI:2429562
Name: transgene insertion 8, Snorri S Thorgeirsson
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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HT Experiment
E-GEOD-71381 | E2f regulation of gene expression in the liver [12 mo]
Series Id: GSE71381
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Allele
Tg(Pim1-E2F1)5Rebr | MGI:3527138
Name: transgene insertion 5, Rene Bernards
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Genotype
Genotype
Symbol: Tg(Alb-E2F1)8Sst/?
Background: involves: C57BL/6J * CBA/J
Zygosity: ot
Has Mutant Allele: true
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Publication
11429786 | J:70633
First Author: Wang D
Year: 2001
Journal: Mol Carcinog
Title: Deregulated expression of DP1 induces epidermal proliferation and enhances skin carcinogenesis.
Volume: 31
Issue: 2
Pages: 90-100
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Allele
Tg(E2F1-luc)1Ech | MGI:5648123
Name: transgene insertion 1, Eric C Holland
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Gt(ROSA)26Sor<tm1(Pim1-E2F1)Rebr> | MGI:4940857
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Rene Bernards
Allele Type: Targeted
Attribute String: Conditional ready, Humanized sequence, Inserted expressed sequence, Reporter
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Allele
Tg(KRT5-E2F1)1Dgj | MGI:2384615
Name: transgene insertion 1, David G Johnson
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Publication
17006931 | J:115787
First Author: Coulouarn C
Year: 2006
Journal: Hepatology
Title: Oncogene-specific gene expression signatures at preneoplastic stage in mice define distinct mechanisms of hepatocarcinogenesis.
Volume: 44
Issue: 4
Pages: 1003-11
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Strain
MGI:5882804 | FVB/N-Tg(E2F1-luc)1Ech/Kctt
Attribute String: coisogenic, mutant strain, transgenic
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Publication
15502845 | J:93965
First Author: Uhrbom L
Year: 2004
Journal: Nat Med
Title: Dissecting tumor maintenance requirements using bioluminescence imaging of cell proliferation in a mouse glioma model.
Volume: 10
Issue: 11
Pages: 1257-60
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Allele
E2f3<tm5(E2f1)Gle> | MGI:3806823
Name: E2F transcription factor 3; targeted mutation 5, Gustavo Leone
Allele Type: Targeted
Attribute String: Inserted expressed sequence, Null/knockout
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Genotype
Genotype
Symbol: Tg(KRT5-E2F1)2Dgj/?
Background: involves: C57BL/6 * SJL/J *SKH1
Zygosity: ot
Has Mutant Allele: true
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Publication
12934101 | J:85354
First Author: Berton TR
Year: 2003
Journal: Oncogene
Title: Tumor formation in mice with conditional inactivation of Brca1 in epithelial tissues.
Volume: 22
Issue: 35
Pages: 5415-26
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Publication
15220935 | J:91632
First Author: Calvisi DF
Year: 2004
Journal: Lab Invest
Title: Disregulation of E-cadherin in transgenic mouse models of liver cancer.
Volume: 84
Issue: 9
Pages: 1137-47
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Protein
Q3UFM7
Organism: Mus musculus/domesticus
Length: 76  
Fragment?: true
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Protein Domain
IPR015030 | RB_C
Type: Domain
Description: The RB C-terminal domain is required for high-affinity binding to E2F-DP complexes and for maximal repression of E2F-responsive promoters, thereby acting as a growth suppressor by blocking the G1-S transition of the cell cycle. This domain has a strand-loop-helix structure, which directly interacts with both E2F1 and DP1, followed by a tail segment that lacks regular secondary structure [].
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HT Experiment
GSE182721 | Lats1/2 control TGF-beta directed EMT in the dorsal cranial neuroepithelium through YAP regulation
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Genotype
Genotype
Symbol: Brca1/Brca1<+> Tg(KRT5-E2F1)2Dgj/?
Background: involves: 129S6/SvEvTac * C57BL/6 * SJL
Zygosity: cx
Has Mutant Allele: true
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Publication
15565109 | J:95489
First Author: Lee JS
Year: 2004
Journal: Nat Genet
Title: Application of comparative functional genomics to identify best-fit mouse models to study human cancer.
Volume: 36
Issue: 12
Pages: 1306-11
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Protein Domain
IPR033576 | CDCA7
Type: Family
Description: Cell division cycle-associated protein 7 (CDCA7/JPO1) is a transcription regulator whose expression is activated by c-Myc and by E2F1 []. CDCA7 can associate with Myc in a phosphorylation-dependent manner. CDCA7 phosphorylation by AKT leads to loss of its association with Myc []. This interaction affects Myc-dependent apoptosis and transformation [, , ]. CDCA7 has also been identified as a Notch target involved in hematopoietic stem cell emergence [].
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Publication
15885355 | J:101128
First Author: Calvisi DF
Year: 2005
Journal: J Hepatol
Title: Activation of the canonical Wnt/beta-catenin pathway confers growth advantages in c-Myc/E2F1 transgenic mouse model of liver cancer.
Volume: 42
Issue: 6
Pages: 842-9
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Genotype
Genotype
Symbol: Brca1/Brca1 Tg(KRT5-E2F1)2Dgj/?
Background: involves: 129S6/SvEvTac * C57BL/6 * SJL
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: E2f1/E2f1 E2f3/E2f3
Background: involves: 129S4/SvJae * 129S6/SvEvTac * FVB/N * NIH Black Swiss
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tmem163/?
Background: involves: 129P2/OlaHsd * FVB * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gtf2ird1/Gtf2ird1<+> Tg(Alb-E2F1)8Sst/?
Background: involves: C57BL/6 * CBA
Zygosity: cx
Has Mutant Allele: true
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Publication
16580749 | -
First Author: Goto Y
Year: 2006
Journal: Biochim Biophys Acta
Title: JPO1/CDCA7, a novel transcription factor E2F1-induced protein, possesses intrinsic transcriptional regulator activity.
Volume: 1759
Issue: 1-2
Pages: 60-8
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Protein
A2AR39
Organism: Mus musculus/domesticus
Length: 192  
Fragment?: true
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Publication
23166294 | J:194226
First Author: Gill RM
Year: 2013
Journal: Mol Cell Biol
Title: The MYC-associated protein CDCA7 is phosphorylated by AKT to regulate MYC-dependent apoptosis and transformation.
Volume: 33
Issue: 3
Pages: 498-513
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