| Type |
Details |
Score |
| Publication |
| First Author: |
Westendorp B |
| Year: |
2012 |
| Journal: |
FASEB J |
| Title: |
The E2F6 repressor activates gene expression in myocardium resulting in dilated cardiomyopathy. |
| Volume: |
26 |
| Issue: |
6 |
| Pages: |
2569-79 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Amanai M |
| Year: |
2006 |
| Journal: |
Biol Reprod |
| Title: |
A restricted role for sperm-borne microRNAs in mammalian fertilization. |
| Volume: |
75 |
| Issue: |
6 |
| Pages: |
877-84 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Park JY |
| Year: |
2016 |
| Journal: |
Development |
| Title: |
The apical complex protein Pals1 is required to maintain cerebellar progenitor cells in a proliferative state. |
| Volume: |
143 |
| Issue: |
1 |
| Pages: |
133-46 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nie X |
| Year: |
2018 |
| Journal: |
PLoS Genet |
| Title: |
mTOR acts as a pivotal signaling hub for neural crest cells during craniofacial development. |
| Volume: |
14 |
| Issue: |
7 |
| Pages: |
e1007491 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Katoh K |
| Year: |
2012 |
| Journal: |
J Neurosci |
| Title: |
G9a histone methyltransferase activity in retinal progenitors is essential for proper differentiation and survival of mouse retinal cells. |
| Volume: |
32 |
| Issue: |
49 |
| Pages: |
17658-70 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bertol JW |
| Year: |
2022 |
| Journal: |
Development |
| Title: |
TWIST1 interacts with β/δ-catenins during neural tube development and regulates fate transition in cranial neural crest cells. |
| Volume: |
149 |
| Issue: |
15 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Dani N |
| Year: |
2021 |
| Journal: |
Cell |
| Title: |
A cellular and spatial map of the choroid plexus across brain ventricles and ages. |
| Volume: |
184 |
| Issue: |
11 |
| Pages: |
3056-3074.e21 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang Q |
| Year: |
2018 |
| Journal: |
Cell Death Dis |
| Title: |
Temporal requirements for ISL1 in sympathetic neuron proliferation, differentiation, and diversification. |
| Volume: |
9 |
| Issue: |
2 |
| Pages: |
247 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lee DR |
| Year: |
2022 |
| Journal: |
Elife |
| Title: |
Transcriptional heterogeneity of ventricular zone cells in the ganglionic eminences of the mouse forebrain. |
| Volume: |
11 |
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Herriges JC |
| Year: |
2012 |
| Journal: |
Dev Dyn |
| Title: |
Genome-scale study of transcription factor expression in the branching mouse lung. |
| Volume: |
241 |
| Issue: |
9 |
| Pages: |
1432-53 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Akagawa R |
| Year: |
2021 |
| Journal: |
Front Cell Dev Biol |
| Title: |
Alternative Functions of Cell Cycle-Related and DNA Repair Proteins in Post-mitotic Neurons. |
| Volume: |
9 |
|
| Pages: |
753175 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kawai J |
| Year: |
2001 |
| Journal: |
Nature |
| Title: |
Functional annotation of a full-length mouse cDNA collection. |
| Volume: |
409 |
| Issue: |
6821 |
| Pages: |
685-90 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Okazaki Y |
| Year: |
2002 |
| Journal: |
Nature |
| Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
| Volume: |
420 |
| Issue: |
6915 |
| Pages: |
563-73 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Fu H |
| Year: |
2009 |
| Journal: |
J Neurosci |
| Title: |
A genome-wide screen for spatially restricted expression patterns identifies transcription factors that regulate glial development. |
| Volume: |
29 |
| Issue: |
36 |
| Pages: |
11399-408 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Campbell GR |
| Year: |
2011 |
| Journal: |
Mol Cell Neurosci |
| Title: |
Transcription factors expressed in olfactory bulb local progenitor cells revealed by genome-wide transcriptome profiling. |
| Volume: |
46 |
| Issue: |
2 |
| Pages: |
548-61 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Koss M |
| Year: |
2012 |
| Journal: |
Dev Cell |
| Title: |
Congenital asplenia in mice and humans with mutations in a Pbx/Nkx2-5/p15 module. |
| Volume: |
22 |
| Issue: |
5 |
| Pages: |
913-26 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Shanghai Model Organisms Center |
| Year: |
2017 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Collin GB |
| Year: |
2020 |
| Journal: |
Cells |
| Title: |
Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss. |
| Volume: |
9 |
| Issue: |
4 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tang F |
| Year: |
2011 |
| Journal: |
PLoS One |
| Title: |
Deterministic and stochastic allele specific gene expression in single mouse blastomeres. |
| Volume: |
6 |
| Issue: |
6 |
| Pages: |
e21208 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Birgit Meldal and Sandra Orchard (1). (1) European Bioinformatics Institute (EBI), Hinxton, Cambridgeshire, United Kingdom |
| Year: |
2023 |
|
| Title: |
Manual transfer of experimentally-verified manual GO annotation data to homologous complexes by curator judgment of sequence, composition and function similarity |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wiese CB |
| Year: |
2012 |
| Journal: |
Front Neurosci |
| Title: |
A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract. |
| Volume: |
6 |
|
| Pages: |
130 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Guo G |
| Year: |
2010 |
| Journal: |
Dev Cell |
| Title: |
Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. |
| Volume: |
18 |
| Issue: |
4 |
| Pages: |
675-85 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yokoyama S |
| Year: |
2009 |
| Journal: |
Dev Cell |
| Title: |
A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. |
| Volume: |
17 |
| Issue: |
6 |
| Pages: |
836-48 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gray PA |
| Year: |
2004 |
| Journal: |
Science |
| Title: |
Mouse brain organization revealed through direct genome-scale TF expression analysis. |
| Volume: |
306 |
| Issue: |
5705 |
| Pages: |
2255-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Thompson CL |
| Year: |
2014 |
| Journal: |
Neuron |
| Title: |
A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. |
| Volume: |
83 |
| Issue: |
2 |
| Pages: |
309-323 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
GUDMAP Consortium |
| Year: |
2004 |
| Journal: |
www.gudmap.org |
| Title: |
GUDMAP: the GenitoUrinary Development Molecular Anatomy Project |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
The Gene Ontology Consortium |
| Year: |
2014 |
|
| Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
DDB, FB, MGI, GOA, ZFIN curators |
| Year: |
2001 |
|
| Title: |
Gene Ontology annotation through association of InterPro records with GO terms |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Carninci P |
| Year: |
2005 |
| Journal: |
Science |
| Title: |
The transcriptional landscape of the mammalian genome. |
| Volume: |
309 |
| Issue: |
5740 |
| Pages: |
1559-63 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zambrowicz BP |
| Year: |
2003 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
| Volume: |
100 |
| Issue: |
24 |
| Pages: |
14109-14 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
| Year: |
2008 |
| Journal: |
Database Download |
| Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cyagen Biosciences Inc. |
| Year: |
2022 |
|
| Title: |
Cyagen Biosciences Website. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
| Year: |
2011 |
|
| Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
GOA curators |
| Year: |
2016 |
|
| Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
| Year: |
2004 |
| Journal: |
Database Release |
| Title: |
Mouse T31 Radiation Hybrid Data Load |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
The Gene Ontology Consortium |
| Year: |
2010 |
|
| Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Diez-Roux G |
| Year: |
2011 |
| Journal: |
PLoS Biol |
| Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
| Volume: |
9 |
| Issue: |
1 |
| Pages: |
e1000582 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
| Year: |
2010 |
|
| Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
| Year: |
2000 |
| Journal: |
Database Release |
| Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Allen Institute for Brain Science |
| Year: |
2004 |
| Journal: |
Allen Institute |
| Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Group |
| Year: |
2003 |
| Journal: |
Database Procedure |
| Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bairoch A |
| Year: |
1999 |
| Journal: |
Database Release |
| Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics |
| Year: |
2010 |
| Journal: |
Database Release |
| Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
430
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
385
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| HT Experiment |
| Series Id: |
GSE67989 |
| Experiment Type: |
transcription profiling by array |
| Study Type: |
WT vs. Mutant |
| Source: |
ArrayExpress |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Scheijen B |
| Year: |
2003 |
| Journal: |
Mol Cell Biol |
| Title: |
Constitutive E2F1 overexpression delays endochondral bone formation by inhibiting chondrocyte differentiation. |
| Volume: |
23 |
| Issue: |
10 |
| Pages: |
3656-68 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wunderlich M |
| Year: |
2002 |
| Journal: |
Oncogene |
| Title: |
Mdm2 inhibition of p53 induces E2F1 transactivation via p21. |
| Volume: |
21 |
| Issue: |
28 |
| Pages: |
4414-21 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gnanasundram SV |
| Year: |
2017 |
| Journal: |
Nat Commun |
| Title: |
PI3Kδ activates E2F1 synthesis in response to mRNA translation stress. |
| Volume: |
8 |
| Issue: |
1 |
| Pages: |
2103 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Taura M |
| Year: |
2011 |
| Journal: |
Nucleic Acids Res |
| Title: |
MEF/ELF4 transactivation by E2F1 is inhibited by p53. |
| Volume: |
39 |
| Issue: |
1 |
| Pages: |
76-88 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Pierce AM |
| Year: |
1998 |
| Journal: |
Oncogene |
| Title: |
Deregulated expression of E2F1 induces hyperplasia and cooperates with ras in skin tumor development. |
| Volume: |
16 |
| Issue: |
10 |
| Pages: |
1267-76 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zacksenhaus E |
| Year: |
1993 |
| Journal: |
Mol Cell Biol |
| Title: |
A bipartite nuclear localization signal in the retinoblastoma gene product and its importance for biological activity. |
| Volume: |
13 |
| Issue: |
8 |
| Pages: |
4588-99 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang C |
| Year: |
2006 |
| Journal: |
Nat Cell Biol |
| Title: |
Interactions between E2F1 and SirT1 regulate apoptotic response to DNA damage. |
| Volume: |
8 |
| Issue: |
9 |
| Pages: |
1025-31 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Fedele M |
| Year: |
2006 |
| Journal: |
Cell Div |
| Title: |
E2F1 activation is responsible for pituitary adenomas induced by HMGA2 gene overexpression. |
| Volume: |
1 |
|
| Pages: |
17 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhou C |
| Year: |
2009 |
| Journal: |
Mol Endocrinol |
| Title: |
E2F1 induces pituitary tumor transforming gene (PTTG1) expression in human pituitary tumors. |
| Volume: |
23 |
| Issue: |
12 |
| Pages: |
2000-12 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Swiatnicki MR |
| Year: |
2021 |
| Journal: |
Sci Rep |
| Title: |
Metastasis is altered through multiple processes regulated by the E2F1 transcription factor. |
| Volume: |
11 |
| Issue: |
1 |
| Pages: |
9502 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wunderlich M |
| Year: |
2004 |
| Journal: |
Cell Cycle |
| Title: |
MdmX represses E2F1 transactivation. |
| Volume: |
3 |
| Issue: |
4 |
| Pages: |
472-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Olson MV |
| Year: |
2007 |
| Journal: |
Cancer Res |
| Title: |
Transgenic E2F1 expression in the mouse brain induces a human-like bimodal pattern of tumors. |
| Volume: |
67 |
| Issue: |
9 |
| Pages: |
4005-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Palomer X |
| Year: |
2011 |
| Journal: |
PLoS One |
| Title: |
The interplay between NF-kappaB and E2F1 coordinately regulates inflammation and metabolism in human cardiac cells. |
| Volume: |
6 |
| Issue: |
5 |
| Pages: |
e19724 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Blais A |
| Year: |
2002 |
| Journal: |
J Biol Chem |
| Title: |
Regulation of the human cyclin-dependent kinase inhibitor p18INK4c by the transcription factors E2F1 and Sp1. |
| Volume: |
277 |
| Issue: |
35 |
| Pages: |
31679-93 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang Y |
| Year: |
2005 |
| Journal: |
Nucleic Acids Res |
| Title: |
The ErbB3 binding protein Ebp1 interacts with Sin3A to repress E2F1 and AR-mediated transcription. |
| Volume: |
33 |
| Issue: |
18 |
| Pages: |
6024-33 |
|
•
•
•
•
•
|
| Transgene |
| Type: |
transgene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Interaction Experiment |
| Description: |
HMGA2 induces pituitary tumorigenesis by enhancing E2F1 activity. |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Matsumoto N |
| Year: |
2004 |
| Journal: |
Oral Microbiol Immunol |
| Title: |
Role of gene E2f1 in susceptibility to bacterial adherence of oral streptococci to tooth surfaces in mice. |
| Volume: |
19 |
| Issue: |
4 |
| Pages: |
270-6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mans DA |
| Year: |
2013 |
| Journal: |
J Pathol |
| Title: |
Regulation of E2F1 by the von Hippel-Lindau tumour suppressor protein predicts survival in renal cell cancer patients. |
| Volume: |
231 |
| Issue: |
1 |
| Pages: |
117-29 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang B |
| Year: |
2014 |
| Journal: |
Hepatology |
| Title: |
Reciprocal regulation of microRNA-122 and c-Myc in hepatocellular cancer: role of E2F1 and transcription factor dimerization partner 2. |
| Volume: |
59 |
| Issue: |
2 |
| Pages: |
555-66 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Haim Y |
| Year: |
2017 |
| Journal: |
Mol Metab |
| Title: |
ASK1 (MAP3K5) is transcriptionally upregulated by E2F1 in adipose tissue in obesity, molecularly defining a human dys-metabolic obese phenotype. |
| Volume: |
6 |
| Issue: |
7 |
| Pages: |
725-736 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gurha P |
| Year: |
2016 |
| Journal: |
Circ Res |
| Title: |
Knockdown of Plakophilin 2 Downregulates miR-184 Through CpG Hypermethylation and Suppression of the E2F1 Pathway and Leads to Enhanced Adipogenesis In Vitro. |
| Volume: |
119 |
| Issue: |
6 |
| Pages: |
731-50 |
|
•
•
•
•
•
|
| Interaction Experiment |
| Description: |
The association of GSK3 beta with E2F1 facilitates nerve growth factor-induced neural cell differentiation. |
|
•
•
•
•
•
|
| Interaction Experiment |
| Description: |
Epigenetic involvement of Alien/ESET complex in thyroid hormone-mediated repression of E2F1 gene expression and cell proliferation. |
|
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•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:29437 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2020-05-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3578426 |
| Pattern: |
Regionally restricted |
| Stage: |
TS26 |
| Assay Id: |
MGI:6415734 |
| Age: |
embryonic day 18.5 |
|
| Note: |
Expressed in the core of the villus (lamina propria) and the adjacent epithelia, same as the E2f1 expression. |
| Specimen Label: |
4 left |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:29437 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2020-05-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3578426 |
| Pattern: |
Regionally restricted |
| Stage: |
TS26 |
| Assay Id: |
MGI:6415734 |
| Age: |
embryonic day 18.5 |
|
| Note: |
Expressed in the core of the villus (lamina propria) and the adjacent epithelia, same as the E2f1 expression. |
| Specimen Label: |
4 right |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| Allele |
| Name: |
E2F transcription factor 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| Interaction Experiment |
| Description: |
Promoter occupancy of MLL1 histone methyltransferase seems to specify the proliferative and apoptotic functions of E2F1 in a tumour microenvironment. |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Pickard A |
| Year: |
2010 |
| Journal: |
J Cell Sci |
| Title: |
Acetylation of Rb by PCAF is required for nuclear localization and keratinocyte differentiation. |
| Volume: |
123 |
| Issue: |
Pt 21 |
| Pages: |
3718-26 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cartier J |
| Year: |
2011 |
| Journal: |
J Biol Chem |
| Title: |
Cellular inhibitor of apoptosis protein-1 (cIAP1) can regulate E2F1 transcription factor-mediated control of cyclin transcription. |
| Volume: |
286 |
| Issue: |
30 |
| Pages: |
26406-17 |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, mutant strain, endonuclease-mediated mutation |
|
•
•
•
•
•
|
| HT Experiment |
| Series Id: |
GSE71380 |
| Experiment Type: |
transcription profiling by array |
| Study Type: |
WT vs. Mutant |
| Source: |
ArrayExpress |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Robertson KD |
| Year: |
2000 |
| Journal: |
Nat Genet |
| Title: |
DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters. |
| Volume: |
25 |
| Issue: |
3 |
| Pages: |
338-42 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Johnson DG |
| Year: |
1997 |
| Journal: |
Mol Carcinog |
| Title: |
High-affinity binding of the cell cycle-regulated transcription factors E2F1 and E2F4 to benzo[a]pyrene diol epoxide-DNA adducts. |
| Volume: |
20 |
| Issue: |
2 |
| Pages: |
216-23 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhou F |
| Year: |
2008 |
| Journal: |
J Biol Chem |
| Title: |
The association of GSK3 beta with E2F1 facilitates nerve growth factor-induced neural cell differentiation. |
| Volume: |
283 |
| Issue: |
21 |
| Pages: |
14506-15 |
|
•
•
•
•
•
|
| Allele |
| Name: |
transgene insertion 8, Snorri S Thorgeirsson |
| Allele Type: |
Transgenic |
| Attribute String: |
Humanized sequence, Inserted expressed sequence |
|
•
•
•
•
•
|
| HT Experiment |
| Series Id: |
GSE71381 |
| Experiment Type: |
transcription profiling by array |
| Study Type: |
WT vs. Mutant |
| Source: |
ArrayExpress |
|
•
•
•
•
•
|
| Allele |
| Name: |
transgene insertion 5, Rene Bernards |
| Allele Type: |
Transgenic |
| Attribute String: |
Humanized sequence, Inserted expressed sequence |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Tg(Alb-E2F1)8Sst/? |
| Background: |
involves: C57BL/6J * CBA/J |
| Zygosity: |
ot |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang D |
| Year: |
2001 |
| Journal: |
Mol Carcinog |
| Title: |
Deregulated expression of DP1 induces epidermal proliferation and enhances skin carcinogenesis. |
| Volume: |
31 |
| Issue: |
2 |
| Pages: |
90-100 |
|
•
•
•
•
•
|
| Allele |
| Name: |
transgene insertion 1, David G Johnson |
| Allele Type: |
Transgenic |
| Attribute String: |
Humanized sequence, Inserted expressed sequence |
|
•
•
•
•
•
|
| Allele |
| Name: |
gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Rene Bernards |
| Allele Type: |
Targeted |
| Attribute String: |
Conditional ready, Humanized sequence, Inserted expressed sequence, Reporter |
|
•
•
•
•
•
|
| Allele |
| Name: |
transgene insertion 1, Eric C Holland |
| Allele Type: |
Transgenic |
| Attribute String: |
Reporter |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Coulouarn C |
| Year: |
2006 |
| Journal: |
Hepatology |
| Title: |
Oncogene-specific gene expression signatures at preneoplastic stage in mice define distinct mechanisms of hepatocarcinogenesis. |
| Volume: |
44 |
| Issue: |
4 |
| Pages: |
1003-11 |
|
•
•
•
•
•
|
| Allele |
| Name: |
E2F transcription factor 3; targeted mutation 5, Gustavo Leone |
| Allele Type: |
Targeted |
| Attribute String: |
Inserted expressed sequence, Null/knockout |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, mutant strain, transgenic |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Uhrbom L |
| Year: |
2004 |
| Journal: |
Nat Med |
| Title: |
Dissecting tumor maintenance requirements using bioluminescence imaging of cell proliferation in a mouse glioma model. |
| Volume: |
10 |
| Issue: |
11 |
| Pages: |
1257-60 |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Tg(KRT5-E2F1)2Dgj/? |
| Background: |
involves: C57BL/6 * SJL/J *SKH1 |
| Zygosity: |
ot |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|