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Search results 901 to 921 out of 921 for Eya1

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0.021s

Type

Details

Score

Interaction Experiment

Ahmed M (2012)

Description:

EYA1 and SIX1 drive the neuronal developmental program in cooperation with the SWI/SNF chromatin-remodeling complex and SOX2 in the mammalian inner ear.

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Publication

15492887 | -

First Author:	Zhang Y
Year:	2004
Journal:	J Assoc Res Otolaryngol
Title:	A comparative study of Eya1 and Eya4 protein function and its implication in branchio-oto-renal syndrome and DFNA10.
Volume:	5
Issue:	3
Pages:	295-304

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GXD Expression

Probe:	MGI:7526429
Assay Type:	Immunohistochemistry
Annotation Date:	2023-09-18
Strength:	Present
Sex:	Not Specified
Emaps:	EMAPS:3524721
Pattern:	Not Specified
Stage:	TS21
Assay Id:	MGI:7526721
Age:	embryonic day 13.5

Note:	Expressed in a broad group of cells in the less mature apical region throughout the thickness of the epithelium including the site of the future organ of Corti, and overlapped with Eya1 domain.
Specimen Label:	not shown
Detected:	true
Specimen Num:	12

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Publication

21706047 | -

First Author:	Farabaugh SM
Year:	2012
Journal:	Oncogene
Title:	Eya2 is required to mediate the pro-metastatic functions of Six1 via the induction of TGF-β signaling, epithelial-mesenchymal transition, and cancer stem cell properties.
Volume:	31
Issue:	5
Pages:	552-62

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Protein Domain

IPR028473 | EYA2

Type:

Family

Description:

Members of the eye absent (EYA) family were originally characterised in fly eye development. EYA proteins are both transcriptional activators and tyrosine phosphatases [, ], and have been shown to dephosphorylate H2AX, promoting repair and cell survival in the response to DNA damage []. EYA proteins (EYA1-4) are normally expressed early in development [, ]. Their phosphatase activity regulates Six1-Dach-Eya transcriptional effects in precursor cell proliferation and survival in mammalian organogenesis [].EYA2 plays an important role in hypaxial muscle development together with Six1 and Dach2; in this it is functionally redundant with EYA1 []. EYA2 is a necessary co-factor for many of the metastasis promoting functions of Six1 [].

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HT Experiment

GSE102844 | Analysis of the Effect of Fibulin-1 on Fibroblast Growth Factor 8 Signaling


Experiment Type:	transcription profiling by array
Study Type:	WT vs. Mutant
Source:	GEO

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Publication

22908299 | J:189889

First Author:	Singh N
Year:	2012
Journal:	Proc Natl Acad Sci U S A
Title:	Dual recognition of phosphoserine and phosphotyrosine in histone variant H2A.X by DNA damage response protein MCPH1.
Volume:	109
Issue:	36
Pages:	14381-6

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Publication

38486486 | J:346077

First Author:	Hwang GH
Year:	2024
Journal:	Cancer Res
Title:	A Benzarone Derivative Inhibits EYA to Suppress Tumor Growth in SHH Medulloblastoma.
Volume:	84
Issue:	6
Pages:	872-886

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Publication

34942352 | J:356343

First Author:	Clugston A
Year:	2022
Journal:	Genomics
Title:	Chromatin accessibility and microRNA expression in nephron progenitor cells during kidney development.
Volume:	114
Issue:	1
Pages:	278-291

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Publication

35420997 | J:326226

First Author:	Wilson C
Year:	2022
Journal:	JCI Insight
Title:	Sine oculis homeobox homolog 1 plays a critical role in pulmonary fibrosis.
Volume:	7
Issue:	10

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Publication

22669823 | J:185503

First Author:	Yu CT
Year:	2012
Journal:	Development
Title:	COUP-TFII is essential for metanephric mesenchyme formation and kidney precursor cell survival.
Volume:	139
Issue:	13
Pages:	2330-9

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Publication

37183792 | J:341253

First Author:	Baxi A
Year:	2023
Journal:	Dev Dyn
Title:	Transcriptomic analysis reveals the role of SIX1 in mouse cranial neural crest patterning and bone development.
Volume:	252
Issue:	10
Pages:	1303-1315

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Publication

27849571 | J:243771

First Author:	Blanc RS
Year:	2017
Journal:	Mol Cell Biol
Title:	Arginine Methylation by PRMT1 Regulates Muscle Stem Cell Fate.
Volume:	37
Issue:	3

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Publication

31227770 | J:278634

First Author:	Wilkerson BA
Year:	2019
Journal:	Sci Rep
Title:	Open chromatin dynamics in prosensory cells of the embryonic mouse cochlea.
Volume:	9
Issue:	1
Pages:	9060

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Publication

17341163 | -

First Author:	Jemc J
Year:	2007
Journal:	Annu Rev Biochem
Title:	The eyes absent family of phosphotyrosine phosphatases: properties and roles in developmental regulation of transcription.
Volume:	76

Pages:	513-38

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Publication

14628053 | -

First Author:	Tootle TL
Year:	2003
Journal:	Nature
Title:	The transcription factor Eyes absent is a protein tyrosine phosphatase.
Volume:	426
Issue:	6964
Pages:	299-302

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Protein

O08575

Organism:	Mus musculus/domesticus
Length:	532
Fragment?:	false

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Protein

Q811N8

Organism:	Mus musculus/domesticus
Length:	450
Fragment?:	false

•

Protein

Q3UV00

Organism:	Mus musculus/domesticus
Length:	532
Fragment?:	false

•

Protein

Q811N7

Organism:	Mus musculus/domesticus
Length:	502
Fragment?:	false

•

Protein

Q3UR62

Organism:	Mus musculus/domesticus
Length:	614
Fragment?:	true

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