| Type |
Details |
Score |
| Publication |
| First Author: |
Mouse Genome Informatics |
| Year: |
2010 |
| Journal: |
Database Release |
| Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Group |
| Year: |
2003 |
| Journal: |
Database Procedure |
| Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
| Allele |
| Name: |
frizzled class receptor 6; endonuclease-mediated mutation 2, Shanghai Model Organisms Center |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, mutant strain, endonuclease-mediated mutation |
|
•
•
•
•
•
|
| Allele |
| Name: |
frizzled class receptor 6; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Conditional ready, No functional change |
|
•
•
•
•
•
|
| Allele |
| Name: |
gene trap ROSA 26, Philippe Soriano; targeted mutation 6, Jeremy Nathans |
| Allele Type: |
Targeted |
| Attribute String: |
Conditional ready, Inserted expressed sequence, No functional change |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
mutant stock, targeted mutation |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
| HT Experiment |
| Series Id: |
GSE40763 |
| Experiment Type: |
transcription profiling by array |
| Study Type: |
WT vs. Mutant |
| Source: |
ArrayExpress |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Phillips HM |
| Year: |
2005 |
| Journal: |
Circ Res |
| Title: |
Vangl2 acts via RhoA signaling to regulate polarized cell movements during development of the proximal outflow tract. |
| Volume: |
96 |
| Issue: |
3 |
| Pages: |
292-9 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
521
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
526
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
569
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
561
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
476
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
575
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
393
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
102
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
130
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
137
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
253
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hatakeyama J |
| Year: |
2014 |
| Journal: |
Endocr Relat Cancer |
| Title: |
Vangl1 and Vangl2: planar cell polarity components with a developing role in cancer. |
| Volume: |
21 |
| Issue: |
5 |
| Pages: |
R345-56 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Leung V |
| Year: |
2016 |
| Journal: |
Dev Neurobiol |
| Title: |
The planar cell polarity protein Vangl2 is required for retinal axon guidance. |
| Volume: |
76 |
| Issue: |
2 |
| Pages: |
150-65 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yates LL |
| Year: |
2010 |
| Journal: |
Hum Mol Genet |
| Title: |
The planar cell polarity gene Vangl2 is required for mammalian kidney-branching morphogenesis and glomerular maturation. |
| Volume: |
19 |
| Issue: |
23 |
| Pages: |
4663-76 |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
VANGL proteins play important roles in the establishment of planar cell polarity (PCP) []. Vangl2 is required for retinal axon guidance [], kidney-branching morphogenesis and glomerular maturation []. It also plays a role in the orientation of stereociliary bundles in the cochlea and is required for polarization and movement of myocardializing cells in the outflow tract and seems to act via RHOA signaling to regulate this process []. It is required for cell surface localization of FZD3 and FZD6 in the inner ear []. |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Takagishi M |
| Year: |
2020 |
| Journal: |
iScience |
| Title: |
Cytoplasmic Dynein Functions in Planar Polarization of Basal Bodies within Ciliated Cells. |
| Volume: |
23 |
| Issue: |
6 |
| Pages: |
101213 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Khalid AB |
| Year: |
2021 |
| Journal: |
Bone |
| Title: |
GATA4 regulates mesenchymal stem cells via direct transcriptional regulation of the WNT signalosome. |
| Volume: |
144 |
|
| Pages: |
115819 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Xie N |
| Year: |
2024 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Wnt7b acts in concert with Wnt5a to regulate tissue elongation and planar cell polarity via noncanonical Wnt signaling. |
| Volume: |
121 |
| Issue: |
35 |
| Pages: |
e2405217121 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Errami Y |
| Year: |
2013 |
| Journal: |
PLoS One |
| Title: |
ICAD deficiency in human colon cancer and predisposition to colon tumorigenesis: linkage to apoptosis resistance and genomic instability. |
| Volume: |
8 |
| Issue: |
2 |
| Pages: |
e57871 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ho YS |
| Year: |
2016 |
| Journal: |
Stem Cells |
| Title: |
Cardioprotective Actions of TGF?RI Inhibition Through Stimulating Autocrine/Paracrine of Survivin and Inhibiting Wnt in Cardiac Progenitors. |
| Volume: |
34 |
| Issue: |
2 |
| Pages: |
445-55 |
|
•
•
•
•
•
|