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Search results 901 to 1000 out of 1056 for Gal

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Type Details Score
Publication
19506076 | J:153181
First Author: Chrispell JD
Year: 2009
Journal: J Biol Chem
Title: Rdh12 activity and effects on retinoid processing in the murine retina.
Volume: 284
Issue: 32
Pages: 21468-77
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Publication
17475819 | J:147540
First Author: Ahrabi AK
Year: 2007
Journal: J Am Soc Nephrol
Title: PKD1 haploinsufficiency causes a syndrome of inappropriate antidiuresis in mice.
Volume: 18
Issue: 6
Pages: 1740-53
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Publication
17130236 | J:118293
First Author: Kurth I
Year: 2007
Journal: Mol Cell Biol
Title: Targeted disruption of the murine retinal dehydrogenase gene Rdh12 does not limit visual cycle function.
Volume: 27
Issue: 4
Pages: 1370-9
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Publication
14973052 | J:88453
First Author: Lengagne R
Year: 2004
Journal: Cancer Res
Title: Spontaneous vitiligo in an animal model for human melanoma: role of tumor-specific CD8+ T cells.
Volume: 64
Issue: 4
Pages: 1496-501
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Interaction Term
MI:0010 | beta galactosidase complementation
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Allele
Tg(Gal-EGFP)HX109Gsat | MGI:4847070
Name: transgene insertion HX109, GENSAT Project at Rockefeller University
Allele Type: Transgenic
Attribute String: Reporter
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Strain
MGI:7448874 | C57BL/6-Rr364729<em1Almk>
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Genotype
Genotype
Symbol: Rr364729/Rr364729
Background: C57BL/6-Rr364729
Zygosity: hm
Has Mutant Allele: true
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Publication
12588794 | J:82023
First Author: Weil D
Year: 2003
Journal: Hum Mol Genet
Title: Usher syndrome type I G (USH1G) is caused by mutations in the gene encoding SANS, a protein that associates with the USH1C protein, harmonin.
Volume: 12
Issue: 5
Pages: 463-71
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Publication
21680557 | J:174954
First Author: Gerding WM
Year: 2011
Journal: Hum Mol Genet
Title: Ccdc66 null mutation causes retinal degeneration and dysfunction.
Volume: 20
Issue: 18
Pages: 3620-31
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Publication
25759012 | J:251030
 
First Author: Thoenes M
Year: 2015
Journal: Orphanet J Rare Dis
Title: OSBPL2 encodes a protein of inner and outer hair cell stereocilia and is mutated in autosomal dominant hearing loss (DFNA67).
Volume: 10
Pages: 15
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Publication
20705278 | J:169189
First Author: Langmann T
Year: 2010
Journal: Am J Hum Genet
Title: Nonsense mutations in FAM161A cause RP28-associated recessive retinitis pigmentosa.
Volume: 87
Issue: 3
Pages: 376-81
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Publication
19838196 | J:154862
First Author: Kurth I
Year: 2009
Journal: Nat Genet
Title: Mutations in FAM134B, encoding a newly identified Golgi protein, cause severe sensory and autonomic neuropathy.
Volume: 41
Issue: 11
Pages: 1179-81
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Publication
11773002 | -
First Author: Chakarova CF
Year: 2002
Journal: Hum Mol Genet
Title: Mutations in HPRP3, a third member of pre-mRNA splicing factor genes, implicated in autosomal dominant retinitis pigmentosa.
Volume: 11
Issue: 1
Pages: 87-92
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Publication
11017088 | -
First Author: Kutsche K
Year: 2000
Journal: Nat Genet
Title: Mutations in ARHGEF6, encoding a guanine nucleotide exchange factor for Rho GTPases, in patients with X-linked mental retardation.
Volume: 26
Issue: 2
Pages: 247-50
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Publication
32843651 | J:300118
First Author: Zou ZV
Year: 2020
Journal: Sci Rep
Title: Genomic profiling of the transcription factor Zfp148 and its impact on the p53 pathway.
Volume: 10
Issue: 1
Pages: 14156
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Publication
30575733 | J:270376
First Author: Ovadya Y
Year: 2018
Journal: Nat Commun
Title: Impaired immune surveillance accelerates accumulation of senescent cells and aging.
Volume: 9
Issue: 1
Pages: 5435
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Publication
31257027 | J:283591
First Author: Wiel C
Year: 2019
Journal: Cell
Title: BACH1 Stabilization by Antioxidants Stimulates Lung Cancer Metastasis.
Volume: 178
Issue: 2
Pages: 330-345.e22
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Publication
24920589 | J:212101
First Author: Kamiya K
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: An unusually powerful mode of low-frequency sound interference due to defective hair bundles of the auditory outer hair cells.
Volume: 111
Issue: 25
Pages: 9307-12
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Publication
32579919 | J:323576
First Author: Odell SC
Year: 2020
Journal: Cell Rep
Title: Epigenomically Bistable Regions across Neuron-Specific Genes Govern Neuron Eligibility to a Coding Ensemble in the Hippocampus.
Volume: 31
Issue: 12
Pages: 107789
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Publication
34400131 | J:312403
First Author: Pandita A
Year: 2021
Journal: Am J Pathol
Title: Intussusceptive Angiogenesis in Human Metastatic Malignant Melanoma.
Volume: 191
Issue: 11
Pages: 2023-2038
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Publication
34107264 | J:333461
First Author: Cid E
Year: 2021
Journal: Cell Rep
Title: Sublayer- and cell-type-specific neurodegenerative transcriptional trajectories in hippocampal sclerosis.
Volume: 35
Issue: 10
Pages: 109229
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Protein Domain
IPR029963 | XGOAT1
Type: Family
Description: Xyloglucan O-acetyltransferase 1 (XGOAT1, also known as protein altered xyloglucan 4, AXY4) predominantly catalyze 6-O-monoacetylation of Gal residues in the Fuc-Gal-Xyl trisaccharide side chains of xyloglucan oligomers []. Loss of AXY4 transcript results in a complete lack of O-acetyl substituents on xyloglucan in several tissues, except seeds, while the O-acetylation level of other polysaccharides is not affected [].
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Allele
Fbxw8<Gt(RRT057)Byg> | MGI:3526146
Name: F-box and WD-40 domain protein 8; gene trap RRT057, BayGenomics
Allele Type: Gene trapped
Attribute String: Hypomorph, Reporter
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Strain
MGI:5318853 | B6.129P2-Fbxw8<Gt(RRT057)Byg>/JdecJ
Attribute String: mutant strain, gene trap, congenic
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Strain
MGI:5003730 | STOCK Tg(Gal-EGFP)HX109Gsat/Mmucd
Attribute String: mutant stock, transgenic
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Publication
31403694 | J:358880
 
First Author: Chauveau F
Year: 2020
Journal: Sleep
Title: Neuropeptide S promotes wakefulness through the inhibition of sleep-promoting ventrolateral preoptic nucleus neurons.
Volume: 43
Issue: 1
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Publication
31566721 | J:330691
First Author: Federighi G
Year: 2020
Journal: J Comp Neurol
Title: Lumbar spinal cord neurons putatively involved in ejaculation are sexually dimorphic in early postnatal mice.
Volume: 528
Issue: 4
Pages: 624-636
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Publication
31493023 | J:358910
First Author: Walter A
Year: 2019
Journal: Brain Struct Funct
Title: Structural and functional connections between the median and the ventrolateral preoptic nucleus.
Volume: 224
Issue: 9
Pages: 3045-3057
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Publication
27238836 | J:253455
 
First Author: Sangare A
Year: 2016
Journal: Neuropharmacology
Title: Serotonin differentially modulates excitatory and inhibitory synaptic inputs to putative sleep-promoting neurons of the ventrolateral preoptic nucleus.
Volume: 109
Pages: 29-40
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Allele
Angpt2<tm1c(KOMP)Seq> | MGI:5613889
Name: angiopoietin 2; targeted mutation 1c, Susan E Quaggin
Allele Type: Targeted
Attribute String: Conditional ready
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Genotype
Genotype
Symbol: Fbxw8/Fbxw8
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Fbxw8/Fbxw8<+>
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: ht
Has Mutant Allele: true
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Publication
19497882 | -
First Author: Than NG
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: A primate subfamily of galectins expressed at the maternal-fetal interface that promote immune cell death.
Volume: 106
Issue: 24
Pages: 9731-6
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Publication
36934089 | J:334963
First Author: Riva M
Year: 2023
Journal: Nat Commun
Title: Aberrant survival of hippocampal Cajal-Retzius cells leads to memory deficits, gamma rhythmopathies and susceptibility to seizures in adult mice.
Volume: 14
Issue: 1
Pages: 1531
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Allele
Gnptab<tm1.2Ddray> | MGI:6196029
Name: N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits; targeted mutation 1.2, Dennis Drayna
Allele Type: Targeted
Attribute String: Humanized sequence
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Publication
- | J:321631
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2022
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Regulatory Build.
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Publication
30083810 | -
First Author: Zhong R
Year: 2018
Journal: Planta
Title: Xyloglucan O-acetyltransferases from Arabidopsis thaliana and Populus trichocarpa catalyze acetylation of fucosylated galactose residues on xyloglucan side chains.
Volume: 248
Issue: 5
Pages: 1159-1171
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Publication
22195967 | -
First Author: Brzovic PS
Year: 2011
Journal: Mol Cell
Title: The acidic transcription activator Gcn4 binds the mediator subunit Gal11/Med15 using a simple protein interface forming a fuzzy complex.
Volume: 44
Issue: 6
Pages: 942-53
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Publication
3062377 | -
First Author: Suzuki Y
Year: 1988
Journal: Mol Cell Biol
Title: GAL11 protein, an auxiliary transcription activator for genes encoding galactose-metabolizing enzymes in Saccharomyces cerevisiae.
Volume: 8
Issue: 11
Pages: 4991-9
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Publication
1406662 | -
First Author: Suzuki Y
Year: 1992
Journal: Mol Cell Biol
Title: GAL11 protein, an auxiliary transcription activator for genes encoding galactose-metabolizing enzymes in Saccharomyces cerevisiae.
Volume: 12
Issue: 10
Pages: 4806
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Protein Domain
IPR033789 | Gal11_coact
Type: Domain
Description: GAL11/MED15 (mediator of RNA polymerase II transcription subunit 15) acts in the general regulation of GAL structural genes and is required for full expression for several genes in this pathway, including GALs 1,7, and 10 in Saccharomyces cerevisiae []. GAL11 function is dependent on GCN4 functionality and binds GCN4 in a degenerate manner with multiple orientations found at the GCN4-GAL11 interface [, , ]. This entry represents an activator-binding domain of GAL11. The tertiary structure of this domain has been solved and shows a four-helix fold with a small shallow hydrophobic cleft at its centre into which three Gcn4 aromatic/aliphatic residues are inserted [].
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Publication
24219910 | J:223190
First Author: Scheufele F
Year: 2014
Journal: Cell Signal
Title: Evidence for a regulatory role of Cullin-RING E3 ubiquitin ligase 7 in insulin signaling.
Volume: 26
Issue: 2
Pages: 233-239
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Publication
14745002 | J:96775
First Author: Xia L
Year: 2004
Journal: J Cell Biol
Title: Defective angiogenesis and fatal embryonic hemorrhage in mice lacking core 1-derived O-glycans.
Volume: 164
Issue: 3
Pages: 451-9
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Publication
17998335 | J:130238
First Author: Tsutsumi T
Year: 2008
Journal: Mol Cell Biol
Title: Disruption of the Fbxw8 gene results in pre- and postnatal growth retardation in mice.
Volume: 28
Issue: 2
Pages: 743-51
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HT Experiment
GSE264025 | Deletion of Mgat2 in Spermatogonia Blocks Spermatogenesis
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
8689685 | J:34200
First Author: Henkemeyer M
Year: 1996
Journal: Cell
Title: Nuk controls pathfinding of commissural axons in the mammalian central nervous system.
Volume: 86
Issue: 1
Pages: 35-46
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Publication
11511811 | J:70937
First Author: Egan S
Year: 2000
Journal: Glycoconj J
Title: Molecular cloning and expression analysis of a mouse UDP-GlcNAc:Gal(beta1-4)Glc(NAc)-R beta1,3-N-acetylglucosaminyltransferase homologous to Drosophila melanogaster Brainiac and the beta1,3-galactosyltransferase family.
Volume: 17
Issue: 12
Pages: 867-75
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Publication
19075021 | J:147795
First Author: Steirer LM
Year: 2009
Journal: J Biol Chem
Title: The asialoglycoprotein receptor regulates levels of plasma glycoproteins terminating with sialic acid alpha2,6-galactose.
Volume: 284
Issue: 6
Pages: 3777-83
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Publication
12417419 | J:80106
First Author: Stanley P
Year: 2002
Journal: Biochim Biophys Acta
Title: Biological consequences of overexpressing or eliminating N-acetylglucosaminyltransferase-TIII in the mouse.
Volume: 1573
Issue: 3
Pages: 363-8
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Publication
9588205 | J:47338
First Author: Kido M
Year: 1998
Journal: Biochem Biophys Res Commun
Title: Presence of polysialic acid and HNK-1 carbohydrate on brain glycoproteins from beta-1,4-galactosyltransferase-knockout mice.
Volume: 245
Issue: 3
Pages: 860-4
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Publication
27121264 | J:312162
First Author: Botz B
Year: 2016
Journal: Exp Dermatol
Title: Galanin 3 receptor-deficient mice show no alteration in the oxazolone-induced contact dermatitis phenotype.
Volume: 25
Issue: 9
Pages: 725-7
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Publication
17113876 | J:117792
 
First Author: Xia L
Year: 2006
Journal: Methods Enzymol
Title: Targeted disruption of the gene encoding core 1 beta1-3-galactosyltransferase (T-synthase) causes embryonic lethality and defective angiogenesis in mice.
Volume: 416
Pages: 314-31
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Publication
2538923 | J:46870
First Author: Chau V
Year: 1989
Journal: Science
Title: A multiubiquitin chain is confined to specific lysine in a targeted short-lived protein.
Volume: 243
Issue: 4898
Pages: 1576-83
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Publication
23751344 | J:204419
First Author: Takeuchi T
Year: 2013
Journal: Biochem Biophys Res Commun
Title: Mammalian galectins bind galactoseβ1-4fucose disaccharide, a unique structural component of protostomial N-type glycoproteins.
Volume: 436
Issue: 3
Pages: 509-13
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Publication
29106382 | J:272733
First Author: Thomson BR
Year: 2017
Journal: J Clin Invest
Title: Angiopoietin-1 is required for Schlemm's canal development in mice and humans.
Volume: 127
Issue: 12
Pages: 4421-4436
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Publication
30541071 | J:270010
First Author: Pei H
Year: 2019
Journal: Endocrinology
Title: Lateral Hypothalamic Mc3R-Expressing Neurons Modulate Locomotor Activity, Energy Expenditure, and Adiposity in Male Mice.
Volume: 160
Issue: 2
Pages: 343-358
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Publication
27151663 | J:260041
     
First Author: Barnes TD
Year: 2016
Journal: Curr Biol
Title: A Mutation Associated with Stuttering Alters Mouse Pup Ultrasonic Vocalizations.
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Genotype
Genotype
Symbol: Angpt1/Angpt1 Angpt2/Angpt2 Gt(ROSA)26Sor/? Tg(tetO-cre)1Jaw/?
Background: involves: 129 * C57BL/6NCr
Zygosity: cn
Has Mutant Allele: true
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Publication
10859353 | -
First Author: Barnhart MM
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: PapD-like chaperones provide the missing information for folding of pilin proteins.
Volume: 97
Issue: 14
Pages: 7709-14
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Publication
15372038 | -
First Author: Vetsch M
Year: 2004
Journal: Nature
Title: Pilus chaperones represent a new type of protein-folding catalyst.
Volume: 431
Issue: 7006
Pages: 329-33
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Publication
15388931 | -
First Author: Schormann N
Year: 2004
Journal: Acta Crystallogr D Biol Crystallogr
Title: Structure of sperm-specific protein SSP-19 from Caenorhabditis elegans.
Volume: 60
Issue: Pt 10
Pages: 1840-5
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Protein Domain
IPR000843 | HTH_LacI
Type: Domain
Description: The lacI-type HTH domain is a DNA-binding, helix-turn-helix (HTH) domain ofabout 50-60 residues present in the lacI/galR family of transcriptionalregulators involved in metabolic regulation in prokaryotes. Most of thesebacterial regulators recognize sugar-inducers. The family is named after theEscherichia coli lactose operon repressor lacI and galactose operon repressorgalR. LacI-type regulators are present in diverse bacterial genera, in thecytoplasm. The 'helix-turn-helix' DNA-binding motif is located in theN-terminal extremity of these transcriptional regulators. The C-terminal partof lacI-type regulators contains several regions that can be involved in (1)binding of inducers, which are sugars and their analogues and (2)oligomerization. The lac repressor is a tetramer, whilst the gal and cytrepressors are dimers. LacI-type transcriptional regulators are important inthe coordination of catabolic, metabolic and transport operons [, ].Several structures of lacI-type transcriptional regulators have been resolvedand their DNA-binding domain encompasses a headpiece, formed by a fold ofthree helices, followed by a hinge region, which can form a fourth α-helixor hinge-helix. The helix-turn-helix motif comprises thefirst and second helices, the second being called the recognition helix. TheHTH is involved in DNA-binding into the major groove, while the hinge-helixfits into the minor groove and the complete domain specifically recognizes theoperator DNA [].Some proteins known to contain a lacI-type HTH domain:Bacillus subtilis ccpA and ccpB, transcriptional regulators involved inthe catabolic repression of several operons.Salmonella typhimurium fruR, the fructose repressor, involved in theregulation of a large number of operons encoding enzymes which take part incentral pathways of carbon metabolism.Escherichia coli lacI, the lactose operon repressor, serving as a model forgene regulation.Escherichia coli purF and purR, repressors involved in the regulation ofenzymes for purine nucleotide synthesis.Haemophilus influenzae galR, a repressor of the galactose operon.
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Protein Domain
IPR008962 | PapD-like_sf
Type: Homologous_superfamily
Description: The PapD-like superfamily of periplasmic chaperones directs the assembly of over 30 diverse adhesive surface organelles that mediate the attachment of many different pathogenic bacteria to host tissues, a critical early step in the development of disease. PapD, the prototypical chaperone, is necessary for the assembly of P pili. P pili contain the adhesin PapG, which mediates the attachment of uropathogenic Escherichia coli to Gal(alpha) Gal receptors present on kidney cells and are critical for the initiation of pyelonephritis. The PapD-like chaperones consist of two Ig-like domains oriented toward each other, forming L-shaped molecules. In the chaperone-subunit complex, the G1beta strand of the chaperone completes an atypical Ig fold in the subunit by occupying the groove and running parallel to the subunit C-terminal F strand. This donor strand complementation interaction simultaneously stabilises pilus subunits and caps their interactive surfaces, preventing their premature oligomerisation in the periplasm. During pilus biogenesis, the highly conserved N-terminal extension of one subunit has been proposed to displace the chaperone G1beta strand from its neighbouring subunit in a mechanism termed donor strand exchange [].This entry represents the immunoglobulin (Ig)-like β-sandwich domain found in PapD, as well as in other periplasmic chaperone proteins that include FimC and SfaE from E. coli, and Caf1m from Yersinia pestis []. In addition, major sperm proteins (MSP) and other related sperm proteins (such as WR4 and SSP-19) contain an Ig-like domain with a similar structural fold to PapD [, ]. Major sperm proteins are central components in molecular interactions underlying sperm motility, with many isoforms existing in Caenorhabditis elegans.
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Publication
10837462 | J:70300
First Author: Zhou D
Year: 2000
Journal: J Biol Chem
Title: The beta 1,3-galactosyltransferase beta 3GalT-V is a stage-specific embryonic antigen-3 (SSEA-3) synthase.
Volume: 275
Issue: 30
Pages: 22631-4
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Publication
11677243 | J:73644
First Author: Ju T
Year: 2002
Journal: J Biol Chem
Title: Cloning and expression of human core 1 beta1,3-galactosyltransferase.
Volume: 277
Issue: 1
Pages: 178-86
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Publication
7559635 | J:29460
First Author: Gersten KM
Year: 1995
Journal: J Biol Chem
Title: Molecular cloning, expression, chromosomal assignment, and tissue-specific expression of a murine alpha-(1,3)-fucosyltransferase locus corresponding to the human ELAM-1 ligand fucosyl transferase.
Volume: 270
Issue: 42
Pages: 25047-56
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Publication
24152993 | J:302073
First Author: Hoshino H
Year: 2014
Journal: J Histochem Cytochem
Title: KSGal6ST is essential for the 6-sulfation of galactose within keratan sulfate in early postnatal brain.
Volume: 62
Issue: 2
Pages: 145-56
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Publication
12218059 | J:113950
First Author: Akama TO
Year: 2002
Journal: J Biol Chem
Title: Enzymatic synthesis in vitro of the disulfated disaccharide unit of corneal keratan sulfate.
Volume: 277
Issue: 45
Pages: 42505-13
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Publication
1284028 | J:30986
First Author: Chowdhury K
Year: 1992
Journal: Mech Dev
Title: The ubiquitous transactivator Zfp-38 is upregulated during spermatogenesis with differential transcription.
Volume: 39
Issue: 3
Pages: 129-42
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Publication
11485999 | J:182413
First Author: Ramakrishnan B
Year: 2001
Journal: J Biol Chem
Title: alpha-Lactalbumin (LA) stimulates milk beta-1,4-galactosyltransferase I (beta 4Gal-T1) to transfer glucose from UDP-glucose to N-acetylglucosamine. Crystal structure of beta 4Gal-T1 x LA complex with UDP-Glc.
Volume: 276
Issue: 40
Pages: 37665-71
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Publication
9451017 | J:46503
First Author: Breton C
Year: 1998
Journal: Glycobiology
Title: Conserved structural features in eukaryotic and prokaryotic fucosyltransferases.
Volume: 8
Issue: 1
Pages: 87-94
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Publication
10854428 | J:63944
First Author: Keusch JJ
Year: 2000
Journal: J Biol Chem
Title: Cloning of Gb3 synthase, the key enzyme in globo-series glycosphingolipid synthesis, predicts a family of alpha 1, 4-glycosyltransferases conserved in plants, insects, and mammals.
Volume: 275
Issue: 33
Pages: 25315-21
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Publication
7919968 | J:19384
First Author: Alameddine HS
Year: 1994
Journal: Neuromuscul Disord
Title: Expression of a recombinant dystrophin in mdx mice using adenovirus vector.
Volume: 4
Issue: 3
Pages: 193-203
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Publication
20439727 | J:160571
First Author: Yago T
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Core 1-derived O-glycans are essential E-selectin ligands on neutrophils.
Volume: 107
Issue: 20
Pages: 9204-9
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Publication
19401394 | J:151264
First Author: Tribulatti MV
Year: 2009
Journal: J Leukoc Biol
Title: Galectin-8 provides costimulatory and proliferative signals to T lymphocytes.
Volume: 86
Issue: 2
Pages: 371-80
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Publication
17724458 | J:128004
First Author: Milland J
Year: 2007
Journal: Immunol Cell Biol
Title: Carbohydrate residues downstream of the terminal Galalpha(1,3)Gal epitope modulate the specificity of xenoreactive antibodies.
Volume: 85
Issue: 8
Pages: 623-32
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Publication
10430609 | J:56667
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