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Search results 901 to 948 out of 948 for Gpx4

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0.027s

Type

Details

Score

Allele

Gpx4<tm4Marc> | MGI:5769979

Name:	glutathione peroxidase 4; targeted mutation 4, Marcus Conrad
Allele Type:	Targeted
Attribute String:	Dominant negative

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Publication

37542104 | J:340617

First Author:	Van San E
Year:	2023
Journal:	Cell Death Differ
Title:	Ferroptosis contributes to multiple sclerosis and its pharmacological targeting suppresses experimental disease progression.
Volume:	30
Issue:	9
Pages:	2092-2103

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Allele

Tg(Gpx4)#Yana | MGI:6383118

Name:	transgene insertion, Yasuhito Nakagawa
Allele Type:	Transgenic
Attribute String:	Conditional ready, Inserted expressed sequence

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Genotype

Symbol:	Gpx4/Gpx4
Background:	involves: 129S6/SvEvTac * C57BL/6J
Zygosity:	hm
Has Mutant Allele:	true

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Genotype

Symbol:	Gpx4/Gpx4<+>
Background:	involves: 129S6/SvEvTac * C57BL/6J
Zygosity:	ht
Has Mutant Allele:	true

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Publication

37120604 | J:353980

First Author:	Puylaert P
Year:	2023
Journal:	Angiogenesis
Title:	Effect of erythrophagocytosis-induced ferroptosis during angiogenesis in atherosclerotic plaques.
Volume:	26
Issue:	4
Pages:	505-522

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Publication

34998934 | J:348222

First Author:	Chen L
Year:	2022
Journal:	Free Radic Biol Med
Title:	Enhanced defense against ferroptosis ameliorates cognitive impairment and reduces neurodegeneration in 5xFAD mice.
Volume:	180

Pages:	1-12

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Publication

30962574 | J:282892

First Author:	Chu B
Year:	2019
Journal:	Nat Cell Biol
Title:	ALOX12 is required for p53-mediated tumour suppression through a distinct ferroptosis pathway.
Volume:	21
Issue:	5
Pages:	579-591

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Publication

32458004 | J:300209

First Author:	Yusuf RZ
Year:	2020
Journal:	Blood
Title:	Aldehyde dehydrogenase 3a2 protects AML cells from oxidative death and the synthetic lethality of ferroptosis inducers.
Volume:	136
Issue:	11
Pages:	1303-1316

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Publication

36928314 | J:352792

First Author:	Wang ME
Year:	2023
Journal:	J Clin Invest
Title:	RB1-deficient prostate tumor growth and metastasis are vulnerable to ferroptosis induction via the E2F/ACSL4 axis.
Volume:	133
Issue:	10

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Publication

36989949 | J:354813

First Author:	Zhu X
Year:	2023
Journal:	Ecotoxicol Environ Saf
Title:	NLRP3 deficiency protects against hypobaric hypoxia induced neuroinflammation and cognitive dysfunction.
Volume:	255

Pages:	114828

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Publication

35467977 | J:331364

First Author:	Cui S
Year:	2022
Journal:	Proc Natl Acad Sci U S A
Title:	FAF1 blocks ferroptosis by inhibiting peroxidation of polyunsaturated fatty acids.
Volume:	119
Issue:	17
Pages:	e2107189119

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Publication

30787033 | J:275361

First Author:	Amaral EP
Year:	2019
Journal:	J Exp Med
Title:	A major role for ferroptosis in Mycobacterium tuberculosis-induced cell death and tissue necrosis.
Volume:	216
Issue:	3
Pages:	556-570

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Publication

33087576 | J:297121

First Author:	Beharier O
Year:	2020
Journal:	Proc Natl Acad Sci U S A
Title:	PLA2G6 guards placental trophoblasts against ferroptotic injury.
Volume:	117
Issue:	44
Pages:	27319-27328

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Publication

34413521 | J:320416

First Author:	Yao Y
Year:	2021
Journal:	Nat Immunol
Title:	Selenium-GPX4 axis protects follicular helper T cells from ferroptosis.
Volume:	22
Issue:	9
Pages:	1127-1139

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Genotype

Symbol:	Gpx4/Gpx4 Tg(Crx-cre)1Tfur/? Tg(Gpx4)#Yana/?
Background:	involves: C57BL/6 * C57BL/6NCrlj * CBA/JNCrlj * DBA/2
Zygosity:	cn
Has Mutant Allele:	true

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Genotype

Symbol:	Gpx4/Gpx4 Tg(Gpx4)#Yana/?
Background:	involves: C57BL/6 * C57BL/6NCrlj * CBA/JNCrlj * DBA/2 * ICR
Zygosity:	cx
Has Mutant Allele:	true

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Genotype

Symbol:	Gpx4/Gpx4 Tg(Gpx4)#Yana/? Tg(Pgk2-cre)24Shb/?
Background:	involves: C57BL/6 * C57BL/6NCrlj * CBA/JNCrlj * DBA/2 * ICR
Zygosity:	cn
Has Mutant Allele:	true

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Publication

35247718 | J:323351

First Author:	Fernández-García V
Year:	2022
Journal:	Biomed Pharmacother
Title:	NOD1 splenic activation confers ferroptosis protection and reduces macrophage recruitment under pro-atherogenic conditions.
Volume:	148

Pages:	112769

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Publication

35703725 | J:327625

First Author:	Xing G
Year:	2022
Journal:	EMBO Rep
Title:	PPARα alleviates iron overload-induced ferroptosis in mouse liver.
Volume:	23
Issue:	8
Pages:	e52280

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Publication

9126277 | J:39714

First Author:	Esworthy RS
Year:	1997
Journal:	Arch Biochem Biophys
Title:	The Gpx1 gene encodes mitochondrial glutathione peroxidase in the mouse liver.
Volume:	340
Issue:	1
Pages:	59-63

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Publication

12588969 | J:82321

First Author:	Kumaraswamy E
Year:	2003
Journal:	Mol Cell Biol
Title:	Selective removal of the selenocysteine tRNA [Ser]Sec gene (Trsp) in mouse mammary epithelium.
Volume:	23
Issue:	5
Pages:	1477-88

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Publication

37505079 | J:342833

First Author:	Radaelli E
Year:	2023
Journal:	Elife
Title:	Mitochondrial defects caused by PARL deficiency lead to arrested spermatogenesis and ferroptosis.
Volume:	12

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Publication

37875418 | J:358190

First Author:	Liu X
Year:	2023
Journal:	Adv Sci (Weinh)
Title:	FOXA2 Suppression by TRIM36 Exerts Anti-Tumor Role in Colorectal Cancer Via Inducing NRF2/GPX4-Regulated Ferroptosis.
Volume:	10
Issue:	35
Pages:	e2304521

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Publication

33931597 | J:314116

First Author:	Wang Q
Year:	2021
Journal:	Cell Death Dis
Title:	GSTZ1 sensitizes hepatocellular carcinoma cells to sorafenib-induced ferroptosis via inhibition of NRF2/GPX4 axis.
Volume:	12
Issue:	5
Pages:	426

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Publication

36402439 | J:332033

First Author:	Xu P
Year:	2022
Journal:	Free Radic Biol Med
Title:	VDR activation attenuates osteoblastic ferroptosis and senescence by stimulating the Nrf2/GPX4 pathway in age-related osteoporosis.
Volume:	193
Issue:	Pt 2
Pages:	720-735

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Publication

34857917 | J:357709

First Author:	Wang T
Year:	2022
Journal:	Cell Death Differ
Title:	Ferroptosis mediates selective motor neuron death in amyotrophic lateral sclerosis.
Volume:	29
Issue:	6
Pages:	1187-1198

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Publication

17360959 | J:124177

First Author:	Suzuki-Toyota F
Year:	2007
Journal:	Biol Reprod
Title:	Factors maintaining normal sperm tail structure during epididymal maturation studied in Gopc-/- mice.
Volume:	77
Issue:	1
Pages:	71-82

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Publication

20653565 | J:166387

First Author:	Chiu-Ugalde J
Year:	2010
Journal:	Biochem J
Title:	Mutation of megalin leads to urinary loss of selenoprotein P and selenium deficiency in serum, liver, kidneys and brain.
Volume:	431
Issue:	1
Pages:	103-11

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Publication

38114454 | J:360030

First Author:	Zhu H
Year:	2023
Journal:	Cell Death Dis
Title:	Gss deficiency causes age-related fertility impairment via ROS-triggered ferroptosis in the testes of mice.
Volume:	14
Issue:	12
Pages:	845

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Publication

38034017 | J:343232

First Author:	Xue C
Year:	2023
Journal:	Front Endocrinol (Lausanne)
Title:	Aconine attenuates osteoclast-mediated bone resorption and ferroptosis to improve osteoporosis via inhibiting NF-κB signaling.
Volume:	14

Pages:	1234563

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Publication

11905995 | J:74560

First Author:	Liu R
Year:	2002
Journal:	J Neurochem
Title:	Increased mitochondrial antioxidative activity or decreased oxygen free radical propagation prevent mutant SOD1-mediated motor neuron cell death and increase amyotrophic lateral sclerosis-like transgenic mouse survival.
Volume:	80
Issue:	3
Pages:	488-500

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Publication

18638546 | J:141838

First Author:	Dabkowski ER
Year:	2008
Journal:	Free Radic Biol Med
Title:	Mitochondria-specific transgenic overexpression of phospholipid hydroperoxide glutathione peroxidase (GPx4) attenuates ischemia/reperfusion-associated cardiac dysfunction.
Volume:	45
Issue:	6
Pages:	855-65

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Publication

30006533 | J:269625

First Author:	Tang J
Year:	2018
Journal:	Sci Rep
Title:	Damage to the myogenic differentiation of C2C12 cells by heat stress is associated with up-regulation of several selenoproteins.
Volume:	8
Issue:	1
Pages:	10601

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Publication

31479686 | J:282165

First Author:	Homma T
Year:	2019
Journal:	Exp Cell Res
Title:	Edaravone, a free radical scavenger, protects against ferroptotic cell death in vitro.
Volume:	384
Issue:	1
Pages:	111592

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Publication

36572666 | J:334355

First Author:	Guo J
Year:	2022
Journal:	Cell Death Dis
Title:	Hepatocyte-specific TMEM16A deficiency alleviates hepatic ischemia/reperfusion injury via suppressing GPX4-mediated ferroptosis.
Volume:	13
Issue:	12
Pages:	1072

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Publication

38622688 | J:351312

First Author:	Jia KW
Year:	2024
Journal:	Mil Med Res
Title:	Interferon-α stimulates DExH-box helicase 58 to prevent hepatocyte ferroptosis.
Volume:	11
Issue:	1
Pages:	22

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Publication

9237936 | J:329383

First Author:	Cheng WH
Year:	1997
Journal:	J Nutr
Title:	Cellular glutathione peroxidase knockout mice express normal levels of selenium-dependent plasma and phospholipid hydroperoxide glutathione peroxidases in various tissues.
Volume:	127
Issue:	8
Pages:	1445-50

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Publication

39341481 | J:360675

First Author:	Zhang Y
Year:	2024
Journal:	Bone
Title:	Lif-deficiency promote systemic Iron metabolism disorders and increases the susceptibility of osteoblasts to ferroptosis.
Volume:	189

Pages:	117266

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Publication

38505605 | J:347106

First Author:	Tak J
Year:	2024
Journal:	Theranostics
Title:	Dual regulation of NEMO by Nrf2 and miR-125a inhibits ferroptosis and protects liver from endoplasmic reticulum stress-induced injury.
Volume:	14
Issue:	5
Pages:	1841-1859

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Publication

35178161 | J:320620

First Author:	Peng J
Year:	2022
Journal:	Oxid Med Cell Longev
Title:	MPO/HOCl Facilitates Apoptosis and Ferroptosis in the SOD1^G93A Motor Neuron of Amyotrophic Lateral Sclerosis.
Volume:	2022

Pages:	8217663

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Publication

9164985 | J:40843

First Author:	Cheng WH
Year:	1997
Journal:	J Nutr
Title:	Overexpression of cellular glutathione peroxidase does not affect expression of plasma glutathione peroxidase or phospholipid hydroperoxide glutathione peroxidase in mice offered diets adequate or deficient in selenium.
Volume:	127
Issue:	5
Pages:	675-80

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Publication

38579937 | J:348053

First Author:	Torres-Velarde JM
Year:	2024
Journal:	Free Radic Biol Med
Title:	Peroxiredoxin 6 suppresses ferroptosis in lung endothelial cells.
Volume:	218

Pages:	82-93

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Publication

39243573 | J:359342

First Author:	Sanz-Alcázar A
Year:	2024
Journal:	Redox Biol
Title:	Deciphering the ferroptosis pathways in dorsal root ganglia of Friedreich ataxia models. The role of LKB1/AMPK, KEAP1, and GSK3β in the impairment of the NRF2 response.
Volume:	76

Pages:	103339

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Publication

36309297 | J:341727

First Author:	Han P
Year:	2022
Journal:	Free Radic Biol Med
Title:	Inhibition of ferroptosis attenuates oligospermia in male Nrf2 knockout mice.
Volume:	193
Issue:	Pt 1
Pages:	421-429

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Publication

36608588 | J:344506

First Author:	Schwarz M
Year:	2023
Journal:	Redox Biol
Title:	Side-by-side comparison of recombinant human glutathione peroxidases identifies overlapping substrate specificities for soluble hydroperoxides.
Volume:	59

Pages:	102593

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Publication

38272326 | J:345869

First Author:	Shi W
Year:	2024
Journal:	Free Radic Biol Med
Title:	Reprimo (RPRM) mediates neuronal ferroptosis via CREB-Nrf2/SCD1 pathways in radiation-induced brain injury.
Volume:	213

Pages:	343-358

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Publication

29502249 | J:329217

First Author:	Sunde RA
Year:	2018
Journal:	Biol Trace Elem Res
Title:	Impact of Glutathione Peroxidase-1 (Gpx1) Genotype on Selenoenzyme and Transcript Expression When Repleting Selenium-Deficient Mice.
Volume:	186
Issue:	1
Pages:	174-184

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