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Search results 901 to 1000 out of 1071 for Hdac1

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Hits by Strain

Type Details Score
Protein
A0A338P6F0
Organism: Mus musculus/domesticus
Length: 148  
Fragment?: true
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Publication
14627703 | J:87963
First Author: Guo Q
Year: 2004
Journal: J Biol Chem
Title: AATF inhibits aberrant production of amyloid beta peptide 1-42 by interacting directly with Par-4.
Volume: 279
Issue: 6
Pages: 4596-603
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Publication
17699856 | -
First Author: Watanabe Y
Year: 2007
Journal: Clin Cancer Res
Title: PRDM5 identified as a target of epigenetic silencing in colorectal and gastric cancer.
Volume: 13
Issue: 16
Pages: 4786-94
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Publication
21664999 | -
First Author: Burkitt Wright EMM
Year: 2011
Journal: Am J Hum Genet
Title: Mutations in PRDM5 in brittle cornea syndrome identify a pathway regulating extracellular matrix development and maintenance.
Volume: 88
Issue: 6
Pages: 767-777
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Protein Domain
IPR026810 | Tshz3
Type: Family
Description: Teashirt 3 is a transcriptional regulator involved in developmental processes []. It has function in association with APBB1, SET and HDAC factors as a transcriptional repressor, that inhibits the expression of CASP4. TSHZ3-mediated transcription repression involves the recruitment of histone deacetylases HDAC1 and HDAC2. It associates with chromatin in a region surrounding the CASP4 transcriptional start site(s). It regulates the development of neurons involved in both respiratory rhythm and airflow control []. It promotes maintenance of nucleus ambiguus (nA) motoneurons, which govern upper airway function, and establishes a respiratory rhythm generator (RRG) activity compatible with survival at birth. It is involved in the differentiation of the proximal uretic smooth muscle cells during developmental processes []. It is involved in the up-regulation of myocardin, that directs the expression of smooth muscle cells in the proximal ureter [].
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Protein Domain
IPR044415 | PRDM5_PR-SET
Type: Domain
Description: This entry represents the PR/SET domain found in PR domain zinc finger protein 5 (PRDM5). PRDM5 is a sequence-specific DNA-binding transcription factor that represses transcription at least in part by recruitment of the histone methyltransferase EHMT2/G9A and histone deacetylases such as HDAC1 []. Mutation of the PRDM5 gene has been linked to Brittle cornea syndrome 2 (BCS2) [].The PRDM family members are characterised by the presence of a N-terminal PR (PRDI-BF1 and RIZ1 homology) domain followed by multiple zinc fingers which confer DNA binding activity. PR domains are only distantly related to the classical SET methyltransferase domains []. They are involved in epigenetic regulation of gene expression through their intrinsic histone methyltransferase activity or via interactions with other chromatin modifying enzymes [].
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Protein Coding Gene
MGI:1196337 | Brms1l
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
10640276 | J:64684
First Author: Kao HY
Year: 2000
Journal: Genes Dev
Title: Isolation of a novel histone deacetylase reveals that class I and class II deacetylases promote SMRT-mediated repression.
Volume: 14
Issue: 1
Pages: 55-66
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Publication
11006275 | J:113911
First Author: Wei LN
Year: 2000
Journal: J Biol Chem
Title: Receptor-interacting protein 140 directly recruits histone deacetylases for gene silencing.
Volume: 275
Issue: 52
Pages: 40782-7
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Publication
21549307 | J:183196
First Author: Rowbotham SP
Year: 2011
Journal: Mol Cell
Title: Maintenance of silent chromatin through replication requires SWI/SNF-like chromatin remodeler SMARCAD1.
Volume: 42
Issue: 3
Pages: 285-96
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Publication
32855402 | J:297016
First Author: Damal Villivalam S
Year: 2020
Journal: Nat Commun
Title: TET1 is a beige adipocyte-selective epigenetic suppressor of thermogenesis.
Volume: 11
Issue: 1
Pages: 4313
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Publication
35584694 | J:336973
First Author: Benjamin DI
Year: 2022
Journal: Cell Metab
Title: Fasting induces a highly resilient deep quiescent state in muscle stem cells via ketone body signaling.
Volume: 34
Issue: 6
Pages: 902-918.e6
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Publication
29950602 | J:266532
First Author: Li Y
Year: 2018
Journal: Nat Commun
Title: Reducing histone acetylation rescues cognitive deficits in a mouse model of Fragile X syndrome.
Volume: 9
Issue: 1
Pages: 2494
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Publication
16766265 | J:110132
First Author: Fedele M
Year: 2006
Journal: Cancer Cell
Title: HMGA2 induces pituitary tumorigenesis by enhancing E2F1 activity.
Volume: 9
Issue: 6
Pages: 459-71
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Publication
30503211 | J:269586
First Author: Mirza AN
Year: 2019
Journal: Cell
Title: LAP2 Proteins Chaperone GLI1 Movement between the Lamina and Chromatin to Regulate Transcription.
Volume: 176
Issue: 1-2
Pages: 198-212.e15
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Publication
18703590 | J:173055
First Author: Stolt CC
Year: 2008
Journal: Nucleic Acids Res
Title: The transcription factor Sox5 modulates Sox10 function during melanocyte development.
Volume: 36
Issue: 17
Pages: 5427-40
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Publication
28059064 | J:244109
 
First Author: Qi Z
Year: 2017
Journal: Nat Commun
Title: BMP restricts stemness of intestinal Lgr5+ stem cells by directly suppressing their signature genes.
Volume: 8
Pages: 13824
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Publication
22262897 | J:179889
First Author: Qiu Z
Year: 2012
Journal: J Neurosci
Title: The Rett syndrome protein MeCP2 regulates synaptic scaling.
Volume: 32
Issue: 3
Pages: 989-94
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Publication
32062419 | J:338656
First Author: de Jesús TJ
Year: 2020
Journal: iScience
Title: NF-κB c-Rel Dictates the Inflammatory Threshold by Acting as a Transcriptional Repressor.
Volume: 23
Issue: 3
Pages: 100876
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Publication
20360311 | J:185837
First Author: Li HF
Year: 2010
Journal: J Am Soc Nephrol
Title: ATF3-mediated epigenetic regulation protects against acute kidney injury.
Volume: 21
Issue: 6
Pages: 1003-13
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Publication
20826751 | J:164284
First Author: Kwon HJ
Year: 2010
Journal: J Immunol
Title: Vitamin D3 upregulated protein 1 suppresses TNF-α-induced NF-κB activation in hepatocarcinogenesis.
Volume: 185
Issue: 7
Pages: 3980-9
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Publication
23525087 | J:196445
First Author: Do-Umehara HC
Year: 2013
Journal: Nat Immunol
Title: Suppression of inflammation and acute lung injury by Miz1 via repression of C/EBP-δ.
Volume: 14
Issue: 5
Pages: 461-9
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Publication
27425624 | J:238656
First Author: Xue S
Year: 2016
Journal: Cell Rep
Title: TET3 Inhibits Type I IFN Production Independent of DNA Demethylation.
Volume: 16
Issue: 4
Pages: 1096-1105
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Publication
28598443 | J:345539
 
First Author: Xia M
Year: 2017
Journal: Nat Commun
Title: Ash1l and lnc-Smad3 coordinate Smad3 locus accessibility to modulate iTreg polarization and T cell autoimmunity.
Volume: 8
Pages: 15818
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Publication
35402865 | J:323405
First Author: Darden CM
Year: 2022
Journal: iScience
Title: Calcineurin/NFATc2 and PI3K/AKT signaling maintains β-cell identity and function during metabolic and inflammatory stress.
Volume: 25
Issue: 4
Pages: 104125
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Publication
32591534 | J:291786
First Author: Turnbull RE
Year: 2020
Journal: Nat Commun
Title: The MiDAC histone deacetylase complex is essential for embryonic development and has a unique multivalent structure.
Volume: 11
Issue: 1
Pages: 3252
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Publication
23629966 | J:197027
First Author: Contreras AU
Year: 2013
Journal: J Cell Biol
Title: Deacetylation of p53 induces autophagy by suppressing Bmf expression.
Volume: 201
Issue: 3
Pages: 427-37
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Publication
15769944 | J:96750
First Author: Liu DX
Year: 2005
Journal: Genes Dev
Title: Regulation of neuron survival and death by p130 and associated chromatin modifiers.
Volume: 19
Issue: 6
Pages: 719-32
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Publication
16914062 | J:114896
 
First Author: Fedele M
Year: 2006
Journal: Cell Div
Title: E2F1 activation is responsible for pituitary adenomas induced by HMGA2 gene overexpression.
Volume: 1
Pages: 17
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Publication
16969098 | J:115502
First Author: Fedele M
Year: 2006
Journal: Cell Cycle
Title: Critical role of the HMGA2 gene in pituitary adenomas.
Volume: 5
Issue: 18
Pages: 2045-8
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Publication
17239852 | J:119511
First Author: Kim SM
Year: 2007
Journal: Exp Cell Res
Title: The histone methyltransferase activity of WHISTLE is important for the induction of apoptosis and HDAC1-mediated transcriptional repression.
Volume: 313
Issue: 5
Pages: 975-83
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Publication
19114560 | J:145757
First Author: Bottardi S
Year: 2009
Journal: Mol Cell Biol
Title: Ikaros and GATA-1 combinatorial effect is required for silencing of human gamma-globin genes.
Volume: 29
Issue: 6
Pages: 1526-37
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Publication
23123966 | J:192268
First Author: Zhang K
Year: 2013
Journal: Dev Biol
Title: Depletion of Suds3 reveals an essential role in early lineage specification.
Volume: 373
Issue: 2
Pages: 359-72
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Publication
23223453 | J:192550
First Author: Shimazu T
Year: 2013
Journal: Science
Title: Suppression of oxidative stress by β-hydroxybutyrate, an endogenous histone deacetylase inhibitor.
Volume: 339
Issue: 6116
Pages: 211-4
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Publication
18059471 | J:200406
First Author: Winter S
Year: 2008
Journal: EMBO J
Title: 14-3-3 proteins recognize a histone code at histone H3 and are required for transcriptional activation.
Volume: 27
Issue: 1
Pages: 88-99
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Publication
25284223 | J:215524
First Author: Wei N
Year: 2014
Journal: Mol Cell
Title: Oxidative stress diverts tRNA synthetase to nucleus for protection against DNA damage.
Volume: 56
Issue: 2
Pages: 323-32
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Publication
25445594 | J:220293
First Author: Huang X
Year: 2014
Journal: Biochem Biophys Res Commun
Title: Histone deacetylase1 promotes TGF-β1-mediated early chondrogenesis through down-regulating canonical Wnt signaling.
Volume: 453
Issue: 4
Pages: 810-6
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Publication
26354229 | J:227015
 
First Author: Tang YN
Year: 2015
Journal: Nat Commun
Title: Epigenetic regulation of Smad2 and Smad3 by profilin-2 promotes lung cancer growth and metastasis.
Volume: 6
Pages: 8230
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Publication
26598605 | J:236141
First Author: Hagelkruys A
Year: 2015
Journal: Mol Cell Biol
Title: Essential Nonredundant Function of the Catalytic Activity of Histone Deacetylase 2 in Mouse Development.
Volume: 36
Issue: 3
Pages: 462-74
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Publication
39671488 | J:359856
First Author: Xu X
Year: 2024
Journal: Sci Adv
Title: Nzf2 promotes oligodendrocyte differentiation and regeneration via repressing HDAC1-mediated histone deacetylation.
Volume: 10
Issue: 50
Pages: eadf8405
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Protein Coding Gene
MGI:1929091 | Sinhcaf
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1349481 | Ing1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q9JKX4
Organism: Mus musculus/domesticus
Length: 526  
Fragment?: false
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Protein
A0A1Y7VMJ9
Organism: Mus musculus/domesticus
Length: 76  
Fragment?: false
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Protein
A0A1Y7VJ86
Organism: Mus musculus/domesticus
Length: 88  
Fragment?: true
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Protein
Q3URN5
Organism: Mus musculus/domesticus
Length: 526  
Fragment?: false
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Publication
22993404 | -
First Author: denDekker AD
Year: 2012
Journal: Cancer Res
Title: Rat Mcs1b is concordant to the genome-wide association-identified breast cancer risk locus at human 5q11.2 and MIER3 is a candidate cancer susceptibility gene.
Volume: 72
Issue: 22
Pages: 6002-12
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Protein Coding Gene
MGI:1924057 | Phf12
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1919782 | Sap130
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1096551 | Morf4l1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
14973285 | -
First Author: Manfroid I
Year: 2004
Journal: Development
Title: Three putative murine Teashirt orthologues specify trunk structures in Drosophila in the same way as the Drosophila teashirt gene.
Volume: 131
Issue: 5
Pages: 1065-73
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Publication
11486045 | J:175112
First Author: Iso T
Year: 2001
Journal: Mol Cell Biol
Title: HERP, a novel heterodimer partner of HES/E(spl) in Notch signaling.
Volume: 21
Issue: 17
Pages: 6080-9
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Publication
17301242 | J:219098
First Author: Wiper-Bergeron N
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Glucocorticoid-stimulated preadipocyte differentiation is mediated through acetylation of C/EBPbeta by GCN5.
Volume: 104
Issue: 8
Pages: 2703-8
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Publication
22245780 | J:181181
First Author: Wang W
Year: 2012
Journal: Nat Med
Title: Cidea is an essential transcriptional coactivator regulating mammary gland secretion of milk lipids.
Volume: 18
Issue: 2
Pages: 235-43
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Publication
10444591 | J:56739
First Author: Zhang Y
Year: 1999
Journal: Genes Dev
Title: Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation.
Volume: 13
Issue: 15
Pages: 1924-35
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Publication
15325272 | J:91979
First Author: Iwase S
Year: 2004
Journal: Biochem Biophys Res Commun
Title: Characterization of BHC80 in BRAF-HDAC complex, involved in neuron-specific gene repression.
Volume: 322
Issue: 2
Pages: 601-8
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Publication
26839262 | J:235544
First Author: Ghaleb AM
Year: 2016
Journal: Mol Cancer Res
Title: KLF4 Suppresses Tumor Formation in Genetic and Pharmacological Mouse Models of Colonic Tumorigenesis.
Volume: 14
Issue: 4
Pages: 385-96
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Publication
24495916 | J:216859
First Author: Chaturvedi P
Year: 2014
Journal: Physiol Genomics
Title: Differential regulation of DNA methylation versus histone acetylation in cardiomyocytes during HHcy in vitro and in vivo: an epigenetic mechanism.
Volume: 46
Issue: 7
Pages: 245-55
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Publication
26259605 | J:346356
First Author: Lahoti TS
Year: 2015
Journal: Toxicol Sci
Title: Aryl Hydrocarbon Receptor Activation Synergistically Induces Lipopolysaccharide-Mediated Expression of Proinflammatory Chemokine (c-c motif) Ligand 20.
Volume: 148
Issue: 1
Pages: 229-40
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Publication
22056672 | J:177838
First Author: Papizan JB
Year: 2011
Journal: Genes Dev
Title: Nkx2.2 repressor complex regulates islet β-cell specification and prevents β-to-α-cell reprogramming.
Volume: 25
Issue: 21
Pages: 2291-305
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Publication
39664933 | J:360063
First Author: Astleford-Hopper K
Year: 2025
Journal: JBMR Plus
Title: Lysine specific demethylase 1 conditional myeloid cell knockout mice have decreased osteoclast differentiation due to increased IFN-β gene expression.
Volume: 9
Issue: 1
Pages: ziae142
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Publication
34696786 | J:339467
First Author: Vengoji R
Year: 2021
Journal: J Exp Clin Cancer Res
Title: Differential gene expression-based connectivity mapping identified novel drug candidate and improved Temozolomide efficacy for Glioblastoma.
Volume: 40
Issue: 1
Pages: 335
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Publication
24451378 | J:332478
First Author: Kumar P
Year: 2014
Journal: J Biol Chem
Title: Histone deacetylase inhibitors modulate the transcriptional regulation of guanylyl cyclase/natriuretic peptide receptor-a gene: interactive roles of modified histones, histone acetyltransferase, p300, AND Sp1.
Volume: 289
Issue: 10
Pages: 6991-7002
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Publication
38062245 | J:345824
First Author: Lospinoso Severini L
Year: 2024
Journal: Cell Death Differ
Title: SALL4 is a CRL3(REN/KCTD11) substrate that drives Sonic Hedgehog-dependent medulloblastoma.
Volume: 31
Issue: 2
Pages: 170-187
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Publication
31849603 | J:288461
 
First Author: Kumar V
Year: 2019
Journal: Front Mol Neurosci
Title: Simvastatin Restores HDAC1/2 Activity and Improves Behavioral Deficits in Angelman Syndrome Model Mouse.
Volume: 12
Pages: 289
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Publication
25581517 | J:227940
First Author: Palumbo-Zerr K
Year: 2015
Journal: Nat Med
Title: Orphan nuclear receptor NR4A1 regulates transforming growth factor-β signaling and fibrosis.
Volume: 21
Issue: 2
Pages: 150-8
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Publication
24015760 | J:203807
First Author: Yeh IJ
Year: 2013
Journal: Biochem J
Title: HEXIM1 down-regulates hypoxia-inducible factor-1α protein stability.
Volume: 456
Issue: 2
Pages: 195-204
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Publication
16621892 | J:347130
First Author: Inoue K
Year: 2006
Journal: J Cell Sci
Title: Inefficient reprogramming of the hematopoietic stem cell genome following nuclear transfer.
Volume: 119
Issue: Pt 10
Pages: 1985-91
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Publication
28249899 | J:242170
First Author: Mishra VK
Year: 2017
Journal: Cancer Res
Title: Krüppel-like Transcription Factor KLF10 Suppresses TGFβ-Induced Epithelial-to-Mesenchymal Transition via a Negative Feedback Mechanism.
Volume: 77
Issue: 9
Pages: 2387-2400
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Publication
18264140 | J:138484
First Author: Yoo YG
Year: 2008
Journal: Oncogene
Title: Hepatitis B virus X protein induces the expression of MTA1 and HDAC1, which enhances hypoxia signaling in hepatocellular carcinoma cells.
Volume: 27
Issue: 24
Pages: 3405-13
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Publication
21467841 | J:303147
First Author: Funasaka T
Year: 2011
Journal: Cell Cycle
Title: RNA export factor RAE1 contributes to NUP98-HOXA9-mediated leukemogenesis.
Volume: 10
Issue: 9
Pages: 1456-67
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Publication
24722245 | J:229877
First Author: Feng B
Year: 2014
Journal: Diabetes
Title: Mitogen-activated protein kinase phosphatase 3 (MKP-3)-deficient mice are resistant to diet-induced obesity.
Volume: 63
Issue: 9
Pages: 2924-34
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Publication
32191636 | J:295467
First Author: Wang Z
Year: 2020
Journal: J Clin Invest
Title: E4BP4-mediated inhibition of T follicular helper cell differentiation is compromised in autoimmune diseases.
Volume: 130
Issue: 7
Pages: 3717-3733
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Publication
19029947 | J:200393
First Author: Gulbagci NT
Year: 2009
Journal: EMBO Rep
Title: SHARP1/DEC2 inhibits adipogenic differentiation by regulating the activity of C/EBP.
Volume: 10
Issue: 1
Pages: 79-86
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Publication
28867608 | J:314648
 
First Author: Li F
Year: 2017
Journal: Eur J Pharmacol
Title: Activation of PPARγ inhibits HDAC1-mediated pulmonary arterial smooth muscle cell proliferation and its potential mechanisms.
Volume: 814
Pages: 324-334
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Publication
12202768 | J:113944
First Author: Deplus R
Year: 2002
Journal: Nucleic Acids Res
Title: Dnmt3L is a transcriptional repressor that recruits histone deacetylase.
Volume: 30
Issue: 17
Pages: 3831-8
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Publication
10655483 | J:60199
First Author: Zhou X
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: Identification of a transcriptional repressor related to the noncatalytic domain of histone deacetylases 4 and 5.
Volume: 97
Issue: 3
Pages: 1056-61
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Publication
10748112 | J:62278
First Author: Hu E
Year: 2000
Journal: J Biol Chem
Title: Cloning and characterization of a novel human class I histone deacetylase that functions as a transcription repressor.
Volume: 275
Issue: 20
Pages: 15254-64
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Publication
9468140 | J:45986
First Author: Magnaghi-Jaulin L
Year: 1998
Journal: Nature
Title: Retinoblastoma protein represses transcription by recruiting a histone deacetylase.
Volume: 391
Issue: 6667
Pages: 601-5
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Publication
10220385 | J:56457
First Author: Grozinger CM
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Three proteins define a class of human histone deacetylases related to yeast Hda1p.
Volume: 96
Issue: 9
Pages: 4868-73
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Publication
12082111 | J:78776
First Author: Tsai SC
Year: 2002
Journal: J Biol Chem
Title: Regulation of histone deacetylase 2 by protein kinase CK2.
Volume: 277
Issue: 35
Pages: 31826-33
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Publication
15606500 | J:94642
First Author: Djabali K
Year: 2004
Journal: Differentiation
Title: Hairless contains a novel nuclear matrix targeting signal and associates with histone deacetylase 3 in nuclear speckles.
Volume: 72
Issue: 8
Pages: 410-8
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Publication
15536134 | J:94731
First Author: Aguilera C
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Recruitment of IkappaBalpha to the hes1 promoter is associated with transcriptional repression.
Volume: 101
Issue: 47
Pages: 16537-42
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Publication
16787918 | J:116885
First Author: Mayanil CS
Year: 2006
Journal: J Biol Chem
Title: Regulation of murine TGFbeta2 by Pax3 during early embryonic development.
Volume: 281
Issue: 34
Pages: 24544-52
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Publication
18625706 | J:142328
First Author: Trivedi CM
Year: 2008
Journal: J Biol Chem
Title: Transgenic overexpression of Hdac3 in the heart produces increased postnatal cardiac myocyte proliferation but does not induce hypertrophy.
Volume: 283
Issue: 39
Pages: 26484-9
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Publication
19661918 | J:152901
First Author: Luo SW
Year: 2009
Journal: EMBO J
Title: Regulation of heterochromatin remodelling and myogenin expression during muscle differentiation by FAK interaction with MBD2.
Volume: 28
Issue: 17
Pages: 2568-82
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Publication
19828821 | J:154056
First Author: Koshibu K
Year: 2009
Journal: J Neurosci
Title: Protein phosphatase 1 regulates the histone code for long-term memory.
Volume: 29
Issue: 41
Pages: 13079-89
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Publication
19619530 | J:154490
First Author: Sandoval R
Year: 2009
Journal: Exp Cell Res
Title: Deletion of the p107/p130-binding domain of Mip130/LIN-9 bypasses the requirement for CDK4 activity for the dissociation of Mip130/LIN-9 from p107/p130-E2F4 complex.
Volume: 315
Issue: 17
Pages: 2914-20
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