| Type |
Details |
Score |
| Publication |
| First Author: |
Zhu L |
| Year: |
2018 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Klotho controls the brain-immune system interface in the choroid plexus. |
| Volume: |
115 |
| Issue: |
48 |
| Pages: |
E11388-E11396 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Man SM |
| Year: |
2014 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Actin polymerization as a key innate immune effector mechanism to control Salmonella infection. |
| Volume: |
111 |
| Issue: |
49 |
| Pages: |
17588-93 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lightfield KL |
| Year: |
2008 |
| Journal: |
Nat Immunol |
| Title: |
Critical function for Naip5 in inflammasome activation by a conserved carboxy-terminal domain of flagellin. |
| Volume: |
9 |
| Issue: |
10 |
| Pages: |
1171-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kajiwara Y |
| Year: |
2014 |
| Journal: |
J Immunol |
| Title: |
A critical role for human caspase-4 in endotoxin sensitivity. |
| Volume: |
193 |
| Issue: |
1 |
| Pages: |
335-43 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Demarco B |
| Year: |
2020 |
| Journal: |
Sci Adv |
| Title: |
Caspase-8-dependent gasdermin D cleavage promotes antimicrobial defense but confers susceptibility to TNF-induced lethality. |
| Volume: |
6 |
| Issue: |
47 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Csóka B |
| Year: |
2015 |
| Journal: |
FASEB J |
| Title: |
Extracellular ATP protects against sepsis through macrophage P2X7 purinergic receptors by enhancing intracellular bacterial killing. |
| Volume: |
29 |
| Issue: |
9 |
| Pages: |
3626-37 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Qiao C |
| Year: |
2017 |
| Journal: |
Mol Neurobiol |
| Title: |
Caspase-1 Deficiency Alleviates Dopaminergic Neuronal Death via Inhibiting Caspase-7/AIF Pathway in MPTP/p Mouse Model of Parkinson's Disease. |
| Volume: |
54 |
| Issue: |
6 |
| Pages: |
4292-4302 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mitchell PS |
| Year: |
2020 |
| Journal: |
Elife |
| Title: |
NAIP-NLRC4-deficient mice are susceptible to shigellosis. |
| Volume: |
9 |
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jamilloux Y |
| Year: |
2013 |
| Journal: |
Glia |
| Title: |
Inflammasome activation restricts Legionella pneumophila replication in primary microglial cells through flagellin detection. |
| Volume: |
61 |
| Issue: |
4 |
| Pages: |
539-49 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang J |
| Year: |
2019 |
| Journal: |
J Immunol |
| Title: |
Gasdermin D Protects from Melioidosis through Pyroptosis and Direct Killing of Bacteria. |
| Volume: |
202 |
| Issue: |
12 |
| Pages: |
3468-3473 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Desbien AL |
| Year: |
2015 |
| Journal: |
Eur J Immunol |
| Title: |
Squalene emulsion potentiates the adjuvant activity of the TLR4 agonist, GLA, via inflammatory caspases, IL-18, and IFN-γ. |
| Volume: |
45 |
| Issue: |
2 |
| Pages: |
407-17 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mariathasan S |
| Year: |
2005 |
| Journal: |
J Exp Med |
| Title: |
Innate immunity against Francisella tularensis is dependent on the ASC/caspase-1 axis. |
| Volume: |
202 |
| Issue: |
8 |
| Pages: |
1043-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cieniewicz B |
| Year: |
2015 |
| Journal: |
J Virol |
| Title: |
Murine Gammaherpesvirus 68 Pathogenesis Is Independent of Caspase-1 and Caspase-11 in Mice and Impairs Interleukin-1β Production upon Extrinsic Stimulation in Culture. |
| Volume: |
89 |
| Issue: |
13 |
| Pages: |
6562-74 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zoccal KF |
| Year: |
2016 |
| Journal: |
Nat Commun |
| Title: |
Opposing roles of LTB4 and PGE2 in regulating the inflammasome-dependent scorpion venom-induced mortality. |
| Volume: |
7 |
|
| Pages: |
10760 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yang Q |
| Year: |
2015 |
| Journal: |
Am J Pathol |
| Title: |
Type I interferon contributes to noncanonical inflammasome activation, mediates immunopathology, and impairs protective immunity during fatal infection with lipopolysaccharide-negative ehrlichiae. |
| Volume: |
185 |
| Issue: |
2 |
| Pages: |
446-61 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sarkar A |
| Year: |
2006 |
| Journal: |
Am J Respir Crit Care Med |
| Title: |
Caspase-1 regulates Escherichia coli sepsis and splenic B cell apoptosis independently of interleukin-1beta and interleukin-18. |
| Volume: |
174 |
| Issue: |
9 |
| Pages: |
1003-10 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Shigeoka AA |
| Year: |
2010 |
| Journal: |
J Immunol |
| Title: |
An inflammasome-independent role for epithelial-expressed Nlrp3 in renal ischemia-reperfusion injury. |
| Volume: |
185 |
| Issue: |
10 |
| Pages: |
6277-85 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
van de Veerdonk FL |
| Year: |
2011 |
| Journal: |
Eur J Immunol |
| Title: |
The inflammasome drives protective Th1 and Th17 cellular responses in disseminated candidiasis. |
| Volume: |
41 |
| Issue: |
8 |
| Pages: |
2260-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gris D |
| Year: |
2010 |
| Journal: |
J Immunol |
| Title: |
NLRP3 plays a critical role in the development of experimental autoimmune encephalomyelitis by mediating Th1 and Th17 responses. |
| Volume: |
185 |
| Issue: |
2 |
| Pages: |
974-81 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Carter JJ |
| Year: |
2021 |
| Journal: |
Exp Eye Res |
| Title: |
Atypical cytomegalovirus retinal disease in pyroptosis-deficient mice with murine acquired immunodeficiency syndrome. |
| Volume: |
209 |
|
| Pages: |
108651 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Li X |
| Year: |
2017 |
| Journal: |
Clin Immunol |
| Title: |
Skin inflammation induced by lupus serum was inhibited in IL-1R deficient mice. |
| Volume: |
180 |
|
| Pages: |
63-68 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Linz BM |
| Year: |
2017 |
| Journal: |
J Immunol |
| Title: |
Innate Immune Cell Recovery Is Positively Regulated by NLRP12 during Emergency Hematopoiesis. |
| Volume: |
198 |
| Issue: |
6 |
| Pages: |
2426-2433 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hsu LC |
| Year: |
2011 |
| Journal: |
Nat Immunol |
| Title: |
IL-1β-driven neutrophilia preserves antibacterial defense in the absence of the kinase IKKβ. |
| Volume: |
12 |
| Issue: |
2 |
| Pages: |
144-50 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Labbé K |
| Year: |
2011 |
| Journal: |
Immunity |
| Title: |
Cellular inhibitors of apoptosis proteins cIAP1 and cIAP2 are required for efficient caspase-1 activation by the inflammasome. |
| Volume: |
35 |
| Issue: |
6 |
| Pages: |
897-907 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hu B |
| Year: |
2010 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Inflammation-induced tumorigenesis in the colon is regulated by caspase-1 and NLRC4. |
| Volume: |
107 |
| Issue: |
50 |
| Pages: |
21635-40 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ippagunta SK |
| Year: |
2010 |
| Journal: |
J Biol Chem |
| Title: |
Inflammasome-independent role of apoptosis-associated speck-like protein containing a CARD (ASC) in T cell priming is critical for collagen-induced arthritis. |
| Volume: |
285 |
| Issue: |
16 |
| Pages: |
12454-62 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Segovia M |
| Year: |
2019 |
| Journal: |
Cancer Cell |
| Title: |
Targeting TMEM176B Enhances Antitumor Immunity and Augments the Efficacy of Immune Checkpoint Blockers by Unleashing Inflammasome Activation. |
| Volume: |
35 |
| Issue: |
5 |
| Pages: |
767-781.e6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Pierini R |
| Year: |
2013 |
| Journal: |
J Immunol |
| Title: |
ASC controls IFN-γ levels in an IL-18-dependent manner in caspase-1-deficient mice infected with Francisella novicida. |
| Volume: |
191 |
| Issue: |
7 |
| Pages: |
3847-57 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lamkanfi M |
| Year: |
2009 |
| Journal: |
Blood |
| Title: |
Caspase-7 deficiency protects from endotoxin-induced lymphocyte apoptosis and improves survival. |
| Volume: |
113 |
| Issue: |
12 |
| Pages: |
2742-5 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Goldberg EL |
| Year: |
2017 |
| Journal: |
Cell Rep |
| Title: |
β-Hydroxybutyrate Deactivates Neutrophil NLRP3 Inflammasome to Relieve Gout Flares. |
| Volume: |
18 |
| Issue: |
9 |
| Pages: |
2077-2087 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chehade L |
| Year: |
2022 |
| Journal: |
Front Cell Neurosci |
| Title: |
Suppression of the necroptotic cell death pathways improves survival in Smn 2B/- mice. |
| Volume: |
16 |
|
| Pages: |
972029 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Thomas PG |
| Year: |
2009 |
| Journal: |
Immunity |
| Title: |
The intracellular sensor NLRP3 mediates key innate and healing responses to influenza A virus via the regulation of caspase-1. |
| Volume: |
30 |
| Issue: |
4 |
| Pages: |
566-75 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Buschor S |
| Year: |
2017 |
| Journal: |
PLoS Pathog |
| Title: |
Innate immunity restricts Citrobacter rodentium A/E pathogenesis initiation to an early window of opportunity. |
| Volume: |
13 |
| Issue: |
6 |
| Pages: |
e1006476 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Inoue H |
| Year: |
2008 |
| Journal: |
Bone |
| Title: |
High levels of serum IL-18 promote cartilage loss through suppression of aggrecan synthesis. |
| Volume: |
42 |
| Issue: |
6 |
| Pages: |
1102-10 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yan S |
| Year: |
2018 |
| Journal: |
J Immunol |
| Title: |
Deficiency of the AIM2-ASC Signal Uncovers the STING-Driven Overreactive Response of Type I IFN and Reciprocal Depression of Protective IFN-γ Immunity in Mycobacterial Infection. |
| Volume: |
200 |
| Issue: |
3 |
| Pages: |
1016-1026 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Burkovetskaya M |
| Year: |
2019 |
| Journal: |
J Neurochem |
| Title: |
Caspase 1 activity influences juvenile Batten disease (CLN3) pathogenesis. |
| Volume: |
148 |
| Issue: |
5 |
| Pages: |
652-668 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Pires S |
| Year: |
2018 |
| Journal: |
Eur J Immunol |
| Title: |
IL-1β activation in response to Staphylococcus aureus lung infection requires inflammasome-dependent and independent mechanisms. |
| Volume: |
48 |
| Issue: |
10 |
| Pages: |
1707-1716 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Shutinoski B |
| Year: |
2020 |
| Journal: |
Microbes Infect |
| Title: |
Ripk3 licenced protection against microbial infection in the absence of Caspase1-11 inflammasome. |
| Volume: |
22 |
| Issue: |
1 |
| Pages: |
40-45 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
He M |
| Year: |
2020 |
| Journal: |
Cell Metab |
| Title: |
An Acetylation Switch of the NLRP3 Inflammasome Regulates Aging-Associated Chronic Inflammation and Insulin Resistance. |
| Volume: |
31 |
| Issue: |
3 |
| Pages: |
580-591.e5 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang L |
| Year: |
2021 |
| Journal: |
J Exp Med |
| Title: |
Type I interferon signaling mediates Mycobacterium tuberculosis-induced macrophage death. |
| Volume: |
218 |
| Issue: |
2 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Shaw PJ |
| Year: |
2010 |
| Journal: |
J Immunol |
| Title: |
Cutting edge: critical role for PYCARD/ASC in the development of experimental autoimmune encephalomyelitis. |
| Volume: |
184 |
| Issue: |
9 |
| Pages: |
4610-4 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ocaña-Morgner C |
| Year: |
2011 |
| Journal: |
J Immunol |
| Title: |
Sphingosine 1-phosphate-induced motility and endocytosis of dendritic cells is regulated by SWAP-70 through RhoA. |
| Volume: |
186 |
| Issue: |
9 |
| Pages: |
5345-55 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Williams CD |
| Year: |
2011 |
| Journal: |
Toxicol Appl Pharmacol |
| Title: |
Role of the Nalp3 inflammasome in acetaminophen-induced sterile inflammation and liver injury. |
| Volume: |
252 |
| Issue: |
3 |
| Pages: |
289-97 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Pereira MS |
| Year: |
2011 |
| Journal: |
Front Microbiol |
| Title: |
The Nlrc4 Inflammasome Contributes to Restriction of Pulmonary Infection by Flagellated Legionella spp. that Trigger Pyroptosis. |
| Volume: |
2 |
|
| Pages: |
33 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kolb R |
| Year: |
2019 |
| Journal: |
Oncogene |
| Title: |
Obesity-associated inflammation promotes angiogenesis and breast cancer via angiopoietin-like 4. |
| Volume: |
38 |
| Issue: |
13 |
| Pages: |
2351-2363 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zamboni DS |
| Year: |
2006 |
| Journal: |
Nat Immunol |
| Title: |
The Birc1e cytosolic pattern-recognition receptor contributes to the detection and control of Legionella pneumophila infection. |
| Volume: |
7 |
| Issue: |
3 |
| Pages: |
318-25 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Schneider KS |
| Year: |
2017 |
| Journal: |
Cell Rep |
| Title: |
The Inflammasome Drives GSDMD-Independent Secondary Pyroptosis and IL-1 Release in the Absence of Caspase-1 Protease Activity. |
| Volume: |
21 |
| Issue: |
13 |
| Pages: |
3846-3859 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Smalley C |
| Year: |
2016 |
| Journal: |
PLoS One |
| Title: |
Rickettsia australis Activates Inflammasome in Human and Murine Macrophages. |
| Volume: |
11 |
| Issue: |
6 |
| Pages: |
e0157231 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
den Hartigh AB |
| Year: |
2023 |
| Journal: |
Commun Biol |
| Title: |
Muscimol inhibits plasma membrane rupture and ninjurin-1 oligomerization during pyroptosis. |
| Volume: |
6 |
| Issue: |
1 |
| Pages: |
1010 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kitur K |
| Year: |
2016 |
| Journal: |
Cell Rep |
| Title: |
Necroptosis Promotes Staphylococcus aureus Clearance by Inhibiting Excessive Inflammatory Signaling. |
| Volume: |
16 |
| Issue: |
8 |
| Pages: |
2219-2230 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Huot-Marchand S |
| Year: |
2022 |
| Journal: |
Front Immunol |
| Title: |
Cigarette smoke-induced gasdermin D activation in bronchoalveolar macrophages and bronchial epithelial cells dependently on NLRP3. |
| Volume: |
13 |
|
| Pages: |
918507 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Dupaul-Chicoine J |
| Year: |
2010 |
| Journal: |
Immunity |
| Title: |
Control of intestinal homeostasis, colitis, and colitis-associated colorectal cancer by the inflammatory caspases. |
| Volume: |
32 |
| Issue: |
3 |
| Pages: |
367-78 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chenery AL |
| Year: |
2019 |
| Journal: |
J Immunol |
| Title: |
Inflammasome-Independent Role for NLRP3 in Controlling Innate Antihelminth Immunity and Tissue Repair in the Lung. |
| Volume: |
203 |
| Issue: |
10 |
| Pages: |
2724-2734 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Vaine CA |
| Year: |
2013 |
| Journal: |
J Immunol |
| Title: |
Tuning innate immune activation by surface texturing of polymer microparticles: the role of shape in inflammasome activation. |
| Volume: |
190 |
| Issue: |
7 |
| Pages: |
3525-32 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kaushal V |
| Year: |
2015 |
| Journal: |
Cell Death Differ |
| Title: |
Neuronal NLRP1 inflammasome activation of Caspase-1 coordinately regulates inflammatory interleukin-1-beta production and axonal degeneration-associated Caspase-6 activation. |
| Volume: |
22 |
| Issue: |
10 |
| Pages: |
1676-86 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Pronin A |
| Year: |
2019 |
| Journal: |
Front Mol Neurosci |
| Title: |
Inflammasome Activation Induces Pyroptosis in the Retina Exposed to Ocular Hypertension Injury. |
| Volume: |
12 |
|
| Pages: |
36 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Fortier A |
| Year: |
2007 |
| Journal: |
Cell Microbiol |
| Title: |
Birc1e/Naip5 rapidly antagonizes modulation of phagosome maturation by Legionella pneumophila. |
| Volume: |
9 |
| Issue: |
4 |
| Pages: |
910-23 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Py BF |
| Year: |
2014 |
| Journal: |
Cell Rep |
| Title: |
Caspase-11 controls interleukin-1β release through degradation of TRPC1. |
| Volume: |
6 |
| Issue: |
6 |
| Pages: |
1122-1128 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kim MK |
| Year: |
2019 |
| Journal: |
J Biol Chem |
| Title: |
Reciprocal negative regulation between the tumor suppressor protein p53 and B cell CLL/lymphoma 6 (BCL6) via control of caspase-1 expression. |
| Volume: |
294 |
| Issue: |
1 |
| Pages: |
299-313 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang H |
| Year: |
2015 |
| Journal: |
Cell Rep |
| Title: |
Reciprocal Regulation between Enterovirus 71 and the NLRP3 Inflammasome. |
| Volume: |
12 |
| Issue: |
1 |
| Pages: |
42-48 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Avbelj M |
| Year: |
2021 |
| Journal: |
Front Immunol |
| Title: |
Cleavage-Mediated Regulation of Myd88 Signaling by Inflammasome-Activated Caspase-1. |
| Volume: |
12 |
|
| Pages: |
790258 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Javanmard Khameneh H |
| Year: |
2019 |
| Journal: |
Front Immunol |
| Title: |
The Inflammasome Adaptor ASC Intrinsically Limits CD4+ T-Cell Proliferation to Help Maintain Intestinal Homeostasis. |
| Volume: |
10 |
|
| Pages: |
1566 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kim LK |
| Year: |
2015 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
AMCase is a crucial regulator of type 2 immune responses to inhaled house dust mites. |
| Volume: |
112 |
| Issue: |
22 |
| Pages: |
E2891-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lipinski S |
| Year: |
2019 |
| Journal: |
EMBO J |
| Title: |
Prdx4 limits caspase-1 activation and restricts inflammasome-mediated signaling by extracellular vesicles. |
| Volume: |
38 |
| Issue: |
20 |
| Pages: |
e101266 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Xiao J |
| Year: |
2018 |
| Journal: |
PLoS Biol |
| Title: |
Gasdermin D mediates the pathogenesis of neonatal-onset multisystem inflammatory disease in mice. |
| Volume: |
16 |
| Issue: |
11 |
| Pages: |
e3000047 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Verhoef PA |
| Year: |
2005 |
| Journal: |
J Immunol |
| Title: |
Inhibitory effects of chloride on the activation of caspase-1, IL-1beta secretion, and cytolysis by the P2X7 receptor. |
| Volume: |
175 |
| Issue: |
11 |
| Pages: |
7623-34 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lv Q |
| Year: |
2021 |
| Journal: |
Acta Pharm Sin B |
| Title: |
Lonicerin targets EZH2 to alleviate ulcerative colitis by autophagy-mediated NLRP3 inflammasome inactivation. |
| Volume: |
11 |
| Issue: |
9 |
| Pages: |
2880-2899 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Strowig T |
| Year: |
2012 |
| Journal: |
Nature |
| Title: |
Inflammasomes in health and disease. |
| Volume: |
481 |
| Issue: |
7381 |
| Pages: |
278-86 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chavarría-Smith J |
| Year: |
2015 |
| Journal: |
Immunol Rev |
| Title: |
The NLRP1 inflammasomes. |
| Volume: |
265 |
| Issue: |
1 |
| Pages: |
22-34 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Malik A |
| Year: |
2017 |
| Journal: |
J Cell Sci |
| Title: |
Inflammasome activation and assembly at a glance. |
| Volume: |
130 |
| Issue: |
23 |
| Pages: |
3955-3963 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhai Z |
| Year: |
2017 |
| Journal: |
Oncogene |
| Title: |
NLRP1 promotes tumor growth by enhancing inflammasome activation and suppressing apoptosis in metastatic melanoma. |
| Volume: |
36 |
| Issue: |
27 |
| Pages: |
3820-3830 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Häcker G |
| Year: |
1994 |
| Journal: |
Biochem Cell Biol |
| Title: |
Expression of candidate cell death genes in cell lines during apoptosis. |
| Volume: |
72 |
| Issue: |
11-12 |
| Pages: |
451-4 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yin YB |
| Year: |
2005 |
| Journal: |
Acta Biochim Biophys Sin (Shanghai) |
| Title: |
Comparative study of apoptosis-related gene loci in human, mouse and rat genomes. |
| Volume: |
37 |
| Issue: |
5 |
| Pages: |
341-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Islam S |
| Year: |
2006 |
| Journal: |
Biochem Biophys Res Commun |
| Title: |
Lipopolysaccharide prevents apoptosis induced by brefeldin A, an endoplasmic reticulum stress agent, in RAW 264.7 cells. |
| Volume: |
340 |
| Issue: |
2 |
| Pages: |
589-96 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Brough D |
| Year: |
2009 |
| Journal: |
Eur J Immunol |
| Title: |
Pannexin-1-dependent caspase-1 activation and secretion of IL-1beta is regulated by zinc. |
| Volume: |
39 |
| Issue: |
2 |
| Pages: |
352-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mezzaroma E |
| Year: |
2011 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
The inflammasome promotes adverse cardiac remodeling following acute myocardial infarction in the mouse. |
| Volume: |
108 |
| Issue: |
49 |
| Pages: |
19725-30 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hitzler I |
| Year: |
2012 |
| Journal: |
J Immunol |
| Title: |
Caspase-1 has both proinflammatory and regulatory properties in Helicobacter infections, which are differentially mediated by its substrates IL-1β and IL-18. |
| Volume: |
188 |
| Issue: |
8 |
| Pages: |
3594-602 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Karatas H |
| Year: |
2013 |
| Journal: |
Science |
| Title: |
Spreading depression triggers headache by activating neuronal Panx1 channels. |
| Volume: |
339 |
| Issue: |
6123 |
| Pages: |
1092-5 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Breyne K |
| Year: |
2014 |
| Journal: |
PLoS One |
| Title: |
Non-classical proIL-1beta activation during mammary gland infection is pathogen-dependent but caspase-1 independent. |
| Volume: |
9 |
| Issue: |
8 |
| Pages: |
e105680 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Paroli AF |
| Year: |
2018 |
| Journal: |
Front Immunol |
| Title: |
NLRP3 Inflammasome and Caspase-1/11 Pathway Orchestrate Different Outcomes in the Host Protection Against Trypanosoma cruzi Acute Infection. |
| Volume: |
9 |
|
| Pages: |
913 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang C |
| Year: |
2012 |
| Journal: |
Hypertension |
| Title: |
Activation of Nod-like receptor protein 3 inflammasomes turns on podocyte injury and glomerular sclerosis in hyperhomocysteinemia. |
| Volume: |
60 |
| Issue: |
1 |
| Pages: |
154-62 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chen L |
| Year: |
2017 |
| Journal: |
Biomed Res Int |
| Title: |
Chlamydia muridarum Infection of Macrophages Stimulates IL-1β Secretion and Cell Death via Activation of Caspase-1 in an RIP3-Independent Manner. |
| Volume: |
2017 |
|
| Pages: |
1592365 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
178
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
360
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
166
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
346
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
337
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yamamoto M |
| Year: |
2004 |
| Journal: |
Genes Cells |
| Title: |
ASC is essential for LPS-induced activation of procaspase-1 independently of TLR-associated signal adaptor molecules. |
| Volume: |
9 |
| Issue: |
11 |
| Pages: |
1055-67 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mariathasan S |
| Year: |
2004 |
| Journal: |
Nature |
| Title: |
Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf. |
| Volume: |
430 |
| Issue: |
6996 |
| Pages: |
213-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ippagunta SK |
| Year: |
2011 |
| Journal: |
Nat Immunol |
| Title: |
The inflammasome adaptor ASC regulates the function of adaptive immune cells by controlling Dock2-mediated Rac activation and actin polymerization. |
| Volume: |
12 |
| Issue: |
10 |
| Pages: |
1010-6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Choi YJ |
| Year: |
2019 |
| Journal: |
Nat Immunol |
| Title: |
SERPINB1-mediated checkpoint of inflammatory caspase activation. |
| Volume: |
20 |
| Issue: |
3 |
| Pages: |
276-287 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
He WT |
| Year: |
2015 |
| Journal: |
Cell Res |
| Title: |
Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion. |
| Volume: |
25 |
| Issue: |
12 |
| Pages: |
1285-98 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Shi J |
| Year: |
2015 |
| Journal: |
Nature |
| Title: |
Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death. |
| Volume: |
526 |
| Issue: |
7575 |
| Pages: |
660-5 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kofoed EM |
| Year: |
2011 |
| Journal: |
Nature |
| Title: |
Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity. |
| Volume: |
477 |
| Issue: |
7366 |
| Pages: |
592-5 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Knodler LA |
| Year: |
2014 |
| Journal: |
Cell Host Microbe |
| Title: |
Noncanonical inflammasome activation of caspase-4/caspase-11 mediates epithelial defenses against enteric bacterial pathogens. |
| Volume: |
16 |
| Issue: |
2 |
| Pages: |
249-256 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ip WKE |
| Year: |
2017 |
| Journal: |
Science |
| Title: |
Anti-inflammatory effect of IL-10 mediated by metabolic reprogramming of macrophages. |
| Volume: |
356 |
| Issue: |
6337 |
| Pages: |
513-519 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sutterwala FS |
| Year: |
2007 |
| Journal: |
J Exp Med |
| Title: |
Immune recognition of Pseudomonas aeruginosa mediated by the IPAF/NLRC4 inflammasome. |
| Volume: |
204 |
| Issue: |
13 |
| Pages: |
3235-45 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Akhter A |
| Year: |
2009 |
| Journal: |
PLoS Pathog |
| Title: |
Caspase-7 activation by the Nlrc4/Ipaf inflammasome restricts Legionella pneumophila infection. |
| Volume: |
5 |
| Issue: |
4 |
| Pages: |
e1000361 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
He Y |
| Year: |
2016 |
| Journal: |
Nature |
| Title: |
NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux. |
| Volume: |
530 |
| Issue: |
7590 |
| Pages: |
354-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jayaraman P |
| Year: |
2010 |
| Journal: |
J Exp Med |
| Title: |
Tim3 binding to galectin-9 stimulates antimicrobial immunity. |
| Volume: |
207 |
| Issue: |
11 |
| Pages: |
2343-54 |
|
•
•
•
•
•
|