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Search results 901 to 1000 out of 1089 for Jak2

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Type Details Score
Publication
34678207 | J:331244
First Author: Muggeo S
Year: 2021
Journal: Stem Cell Reports
Title: PBX1-directed stem cell transcriptional program drives tumor progression in myeloproliferative neoplasm.
Volume: 16
Issue: 11
Pages: 2607-2616
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35294228 | J:322875
First Author: Lee Y
Year: 2022
Journal: Sci Adv
Title: Hematopoietic stem cells temporally transition to thrombopoietin dependence in the fetal liver.
Volume: 8
Issue: 11
Pages: eabm7688
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Publication
35198891 | J:343968
First Author: Wang R
Year: 2022
Journal: iScience
Title: Abi1 mediates airway smooth muscle cell proliferation and airway remodeling via Jak2/STAT3 signaling.
Volume: 25
Issue: 2
Pages: 103833
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Publication
36396719 | J:338366
First Author: Cao HJ
Year: 2023
Journal: Cell Death Differ
Title: ARID2 mitigates hepatic steatosis via promoting the ubiquitination of JAK2.
Volume: 30
Issue: 2
Pages: 383-396
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Publication
30005133 | J:268532
First Author: Zhang Y
Year: 2018
Journal: Stem Cells
Title: JAK2V617F Megakaryocytes Promote Hematopoietic Stem/Progenitor Cell Expansion in Mice Through Thrombopoietin/MPL Signaling.
Volume: 36
Issue: 11
Pages: 1676-1684
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Publication
9551546 | -
First Author: Barford D
Year: 1998
Journal: Structure
Title: Revealing mechanisms for SH2 domain mediated regulation of the protein tyrosine phosphatase SHP-2.
Volume: 6
Issue: 3
Pages: 249-54
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Publication
25043017 | J:217117
First Author: Arranz L
Year: 2014
Journal: Nature
Title: Neuropathy of haematopoietic stem cell niche is essential for myeloproliferative neoplasms.
Volume: 512
Issue: 7512
Pages: 78-81
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Publication
10531356 | J:58151
First Author: Pollack BP
Year: 1999
Journal: J Biol Chem
Title: The human homologue of the yeast proteins Skb1 and Hsl7p interacts with Jak kinases and contains protein methyltransferase activity.
Volume: 274
Issue: 44
Pages: 31531-42
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Publication
10880228 | J:67142
First Author: Gregory RC
Year: 2000
Journal: Cytokine
Title: Subtraction cloning and initial characterization of novel epo-immediate response genes.
Volume: 12
Issue: 7
Pages: 845-57
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Publication
21700930 | J:186600
First Author: Yu L
Year: 2011
Journal: Circ Res
Title: AIP1 prevents graft arteriosclerosis by inhibiting interferon-γ-dependent smooth muscle cell proliferation and intimal expansion.
Volume: 109
Issue: 4
Pages: 418-27
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Publication
14970183 | J:90889
First Author: Shibayama H
Year: 2004
Journal: J Exp Med
Title: Identification of a cytokine-induced antiapoptotic molecule anamorsin essential for definitive hematopoiesis.
Volume: 199
Issue: 4
Pages: 581-92
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Publication
7568026 | J:29298
First Author: Liu X
Year: 1995
Journal: Proc Natl Acad Sci U S A
Title: Cloning and expression of Stat5 and an additional homologue (Stat5b) involved in prolactin signal transduction in mouse mammary tissue.
Volume: 92
Issue: 19
Pages: 8831-5
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Publication
9202127 | J:43734
First Author: Naka T
Year: 1997
Journal: Nature
Title: Structure and function of a new STAT-induced STAT inhibitor.
Volume: 387
Issue: 6636
Pages: 924-9
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Publication
11522790 | J:159012
First Author: Hanada T
Year: 2001
Journal: J Biol Chem
Title: A mutant form of JAB/SOCS1 augments the cytokine-induced JAK/STAT pathway by accelerating degradation of wild-type JAB/CIS family proteins through the SOCS-box.
Volume: 276
Issue: 44
Pages: 40746-54
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Publication
8007943 | J:18883
First Author: Yamamoto K
Year: 1994
Journal: Mol Cell Biol
Title: Stat4, a novel gamma interferon activation site-binding protein expressed in early myeloid differentiation.
Volume: 14
Issue: 7
Pages: 4342-9
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Publication
24645678 | J:214138
First Author: Chen Z
Year: 2014
Journal: Mol Endocrinol
Title: SH2B1 in β-cells promotes insulin expression and glucose metabolism in mice.
Volume: 28
Issue: 5
Pages: 696-705
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10585417 | J:58894
First Author: Kline JB
Year: 1999
Journal: J Biol Chem
Title: Functional characterization of the intermediate isoform of the human prolactin receptor.
Volume: 274
Issue: 50
Pages: 35461-8
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20601111 | J:165456
First Author: Akasaka Y
Year: 2010
Journal: Biochim Biophys Acta
Title: Direct evidence for leptin-induced lipid oxidation independent of long-form leptin receptor.
Volume: 1801
Issue: 10
Pages: 1115-22
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Publication
29204732 | J:327530
First Author: Hu ZJ
Year: 2018
Journal: Neurosci Bull
Title: Peripheral Leptin Signaling Mediates Formalin-Induced Nociception.
Volume: 34
Issue: 2
Pages: 321-329
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Publication
18097472 | J:130891
First Author: Xu L
Year: 2008
Journal: J Clin Invest
Title: Leptin inhibits 4-aminopyridine- and pentylenetetrazole-induced seizures and AMPAR-mediated synaptic transmission in rodents.
Volume: 118
Issue: 1
Pages: 272-80
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Publication
15634925 | J:95832
First Author: Yu WM
Year: 2005
Journal: J Immunol
Title: Abnormal Th1 cell differentiation and IFN-gamma production in T lymphocytes from motheaten viable mice mutant for Src homology 2 domain-containing protein tyrosine phosphatase-1.
Volume: 174
Issue: 2
Pages: 1013-9
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Publication
29535264 | J:260231
 
First Author: Rochman Y
Year: 2018
Journal: Sci Signal
Title: TSLP signaling in CD4+ T cells programs a pathogenic T helper 2 cell state.
Volume: 11
Issue: 521
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Publication
27784744 | J:238005
First Author: Chen Y
Year: 2017
Journal: Cancer Res
Title: Alox5 Blockade Eradicates JAK2V617F-Induced Polycythemia Vera in Mice.
Volume: 77
Issue: 1
Pages: 164-174
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Publication
20980634 | J:166149
First Author: Jeon SB
Year: 2010
Journal: J Immunol
Title: Galectin-3 exerts cytokine-like regulatory actions through the JAK-STAT pathway.
Volume: 185
Issue: 11
Pages: 7037-46
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Publication
30348900 | J:272880
First Author: Rani R
Year: 2018
Journal: J Biol Chem
Title: Mechanisms of concanavalin A-induced cytokine synthesis by hepatic stellate cells: Distinct roles of interferon regulatory factor-1 in liver injury.
Volume: 293
Issue: 48
Pages: 18466-18476
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Publication
34479964 | J:314034
First Author: Yang L
Year: 2021
Journal: Cancer Res
Title: Oxidized Low-Density Lipoprotein Links Hypercholesterolemia and Bladder Cancer Aggressiveness by Promoting Cancer Stemness.
Volume: 81
Issue: 22
Pages: 5720-5732
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Publication
38446698 | J:350972
First Author: Keenan C
Year: 2024
Journal: Blood
Title: Differential effects of itacitinib, fedratinib, and ruxolitinib in mouse models of hemophagocytic lymphohistiocytosis.
Volume: 143
Issue: 23
Pages: 2386-2400
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Publication
12805384 | J:85186
First Author: Chang HC
Year: 2003
Journal: J Biol Chem
Title: STAT4 requires the N-terminal domain for efficient phosphorylation.
Volume: 278
Issue: 34
Pages: 32471-7
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Publication
26282165 | J:225862
First Author: Lau J
Year: 2015
Journal: Cancer Res
Title: STAT3 Blockade Inhibits Radiation-Induced Malignant Progression in Glioma.
Volume: 75
Issue: 20
Pages: 4302-11
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Publication
18209032 | J:131353
First Author: Ha H
Year: 2008
Journal: J Immunol
Title: Stimulation by TLR5 modulates osteoclast differentiation through STAT1/IFN-beta.
Volume: 180
Issue: 3
Pages: 1382-9
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Publication
30979817 | J:274636
First Author: Griesenauer B
Year: 2019
Journal: J Immunol
Title: ST2/MyD88 Deficiency Protects Mice against Acute Graft-versus-Host Disease and Spares Regulatory T Cells.
Volume: 202
Issue: 10
Pages: 3053-3064
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Publication
36452038 | J:332791
 
First Author: de Oliveira Micheletti T
Year: 2022
Journal: Front Physiol
Title: Acute exercise reduces feeding by activating IL-6/Tubby axis in the mouse hypothalamus.
Volume: 13
Pages: 956116
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Publication
23636173 | J:324431
First Author: Hu MC
Year: 2013
Journal: Kidney Int
Title: The erythropoietin receptor is a downstream effector of Klotho-induced cytoprotection.
Volume: 84
Issue: 3
Pages: 468-81
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Publication
20706987 | J:165922
First Author: Peña G
Year: 2010
Journal: Eur J Immunol
Title: Unphosphorylated STAT3 modulates alpha 7 nicotinic receptor signaling and cytokine production in sepsis.
Volume: 40
Issue: 9
Pages: 2580-9
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Publication
19783654 | J:156325
First Author: Tang C
Year: 2009
Journal: J Biol Chem
Title: The macrophage cholesterol exporter ABCA1 functions as an anti-inflammatory receptor.
Volume: 284
Issue: 47
Pages: 32336-43
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Publication
26989082 | J:231656
First Author: Tang C
Year: 2016
Journal: J Lipid Res
Title: Both STAT3 activation and cholesterol efflux contribute to the anti-inflammatory effect of apoA-I/ABCA1 interaction in macrophages.
Volume: 57
Issue: 5
Pages: 848-57
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Publication
24435044 | J:207979
First Author: Zhou B
Year: 2014
Journal: J Clin Invest
Title: Erythropoietin promotes breast tumorigenesis through tumor-initiating cell self-renewal.
Volume: 124
Issue: 2
Pages: 553-63
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Publication
15213094 | J:96513
First Author: Halupa A
Year: 2005
Journal: Blood
Title: A novel role for STAT1 in regulating murine erythropoiesis: deletion of STAT1 results in overall reduction of erythroid progenitors and alters their distribution.
Volume: 105
Issue: 2
Pages: 552-61
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Publication
37846594 | J:341967
 
First Author: Yoshida N
Year: 2023
Journal: Dis Model Mech
Title: The roles of JAK2/STAT3 signaling in fusion of the secondary palate.
Volume: 16
Issue: 10
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Publication
24327953 | J:221309
First Author: Li Z
Year: 2013
Journal: Mol Metab
Title: Phenotypic effects of an induced mutation of the ObRa isoform of the leptin receptor.
Volume: 2
Issue: 4
Pages: 364-75
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Publication
20008276 | J:158438
First Author: Merkel MJ
Year: 2010
Journal: Am J Physiol Heart Circ Physiol
Title: Inhibition of soluble epoxide hydrolase preserves cardiomyocytes: role of STAT3 signaling.
Volume: 298
Issue: 2
Pages: H679-87
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Publication
27694385 | J:237844
First Author: Svoronos N
Year: 2017
Journal: Cancer Discov
Title: Tumor Cell-Independent Estrogen Signaling Drives Disease Progression through Mobilization of Myeloid-Derived Suppressor Cells.
Volume: 7
Issue: 1
Pages: 72-85
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Publication
24552351 | J:212289
First Author: Slavova-Azmanova NS
Year: 2014
Journal: Biochem J
Title: Lyn kinase plays important roles in erythroid expansion, maturation and erythropoietin receptor signalling by regulating inhibitory signalling pathways that control survival.
Volume: 459
Issue: 3
Pages: 455-66
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Publication
20008137 | J:156484
First Author: Kimura A
Year: 2010
Journal: Am J Pathol
Title: The absence of interleukin-6 enhanced arsenite-induced renal injury by promoting autophagy of tubular epithelial cells with aberrant extracellular signal-regulated kinase activation.
Volume: 176
Issue: 1
Pages: 40-50
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Publication
36356831 | J:331384
 
First Author: Vesting AJ
Year: 2022
Journal: Mol Metab
Title: NIK/MAP3K14 in hepatocytes orchestrates NASH to hepatocellular carcinoma progression via JAK2/STAT5 inhibition.
Volume: 66
Pages: 101626
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Publication
16477024 | J:107314
First Author: Heinonen KM
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Protein tyrosine phosphatase 1B negatively regulates macrophage development through CSF-1 signaling.
Volume: 103
Issue: 8
Pages: 2776-81
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Publication
21056972 | J:167531
First Author: Ng DC
Year: 2011
Journal: J Biol Chem
Title: Opposing actions of extracellular signal-regulated kinase (ERK) and signal transducer and activator of transcription 3 (STAT3) in regulating microtubule stabilization during cardiac hypertrophy.
Volume: 286
Issue: 2
Pages: 1576-87
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Publication
20458146 | J:161643
First Author: Bersenev A
Year: 2010
Journal: J Clin Invest
Title: Lnk constrains myeloproliferative diseases in mice.
Volume: 120
Issue: 6
Pages: 2058-69
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Publication
18618018 | J:140879
First Author: Bersenev A
Year: 2008
Journal: J Clin Invest
Title: Lnk controls mouse hematopoietic stem cell self-renewal and quiescence through direct interactions with JAK2.
Volume: 118
Issue: 8
Pages: 2832-44
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Publication
24297922 | J:205505
First Author: Louria-Hayon I
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Lnk adaptor suppresses radiation resistance and radiation-induced B-cell malignancies by inhibiting IL-11 signaling.
Volume: 110
Issue: 51
Pages: 20599-604
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Publication
21636855 | J:176942
First Author: Cudejko C
Year: 2011
Journal: Blood
Title: p16INK4a deficiency promotes IL-4-induced polarization and inhibits proinflammatory signaling in macrophages.
Volume: 118
Issue: 9
Pages: 2556-66
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Publication
21586612 | J:174088
First Author: Corcoran RB
Year: 2011
Journal: Cancer Res
Title: STAT3 plays a critical role in KRAS-induced pancreatic tumorigenesis.
Volume: 71
Issue: 14
Pages: 5020-9
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Publication
18708442 | J:141315
First Author: Goodman MD
Year: 2008
Journal: Am J Physiol Heart Circ Physiol
Title: Regulating RISK: a role for JAK-STAT signaling in postconditioning?
Volume: 295
Issue: 4
Pages: H1649-56
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26573705 | J:324478
First Author: Qin Q
Year: 2016
Journal: Hypertension
Title: Nrf2-Mediated Cardiac Maladaptive Remodeling and Dysfunction in a Setting of Autophagy Insufficiency.
Volume: 67
Issue: 1
Pages: 107-17
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Publication
21846328 | J:179849
First Author: Handy JA
Year: 2011
Journal: Biochem J
Title: Adiponectin inhibits leptin signalling via multiple mechanisms to exert protective effects against hepatic fibrosis.
Volume: 440
Issue: 3
Pages: 385-95
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21220694 | J:169170
First Author: Liontos LM
Year: 2011
Journal: J Immunol
Title: The Src-like adaptor protein regulates GM-CSFR signaling and monocytic dendritic cell maturation.
Volume: 186
Issue: 4
Pages: 1923-33
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Publication
16332976 | J:131264
First Author: Menon MP
Year: 2006
Journal: Blood
Title: Core erythropoietin receptor signals for late erythroblast development.
Volume: 107
Issue: 7
Pages: 2662-72
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Publication
15601831 | J:95149
First Author: Rowland JE
Year: 2005
Journal: Mol Cell Biol
Title: In vivo analysis of growth hormone receptor signaling domains and their associated transcripts.
Volume: 25
Issue: 1
Pages: 66-77
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Publication
24804649 | J:217366
First Author: Judd LM
Year: 2014
Journal: PLoS One
Title: Inhibition of the JAK2/STAT3 pathway reduces gastric cancer growth in vitro and in vivo.
Volume: 9
Issue: 5
Pages: e95993
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Publication
24302626 | J:208707
First Author: Gan Y
Year: 2014
Journal: Endocrinology
Title: Functional collaboration of insulin-like growth factor-1 receptor (IGF-1R), but not insulin receptor (IR), with acute GH signaling in mouse calvarial cells.
Volume: 155
Issue: 3
Pages: 1000-9
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Publication
21864028 | J:305930
First Author: Zhang Q
Year: 2011
Journal: J Interferon Cytokine Res
Title: The role of Tyk2 in regulation of breast cancer growth.
Volume: 31
Issue: 9
Pages: 671-7
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Publication
24293409 | J:208182
First Author: Palagani V
Year: 2014
Journal: Carcinogenesis
Title: Combined inhibition of Notch and JAK/STAT is superior to monotherapies and impairs pancreatic cancer progression.
Volume: 35
Issue: 4
Pages: 859-66
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Publication
21527517 | J:174904
First Author: Zheng Y
Year: 2011
Journal: Blood
Title: A CK2-dependent mechanism for activation of the JAK-STAT signaling pathway.
Volume: 118
Issue: 1
Pages: 156-66
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Publication
25481243 | J:324276
 
First Author: Visconte V
Year: 2014
Journal: J Hematol Oncol
Title: Splicing factor 3b subunit 1 (Sf3b1) haploinsufficient mice display features of low risk Myelodysplastic syndromes with ring sideroblasts.
Volume: 7
Pages: 89
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Publication
36618429 | J:352060
 
First Author: Masgrau-Alsina S
Year: 2022
Journal: Front Immunol
Title: MST1 controls murine neutrophil homeostasis via the G-CSFR/STAT3 axis.
Volume: 13
Pages: 1038936
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Publication
26077624 | J:251062
First Author: Wu G
Year: 2015
Journal: Cardiovasc Res
Title: SH2B1 is critical for the regulation of cardiac remodelling in response to pressure overload.
Volume: 107
Issue: 2
Pages: 203-15
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10477719 | J:57634
First Author: Brown MP
Year: 1999
Journal: Blood
Title: Reconstitution of early lymphoid proliferation and immune function in Jak3-deficient mice by interleukin-3.
Volume: 94
Issue: 6
Pages: 1906-14
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14993294 | J:89031
First Author: Carpino N
Year: 2004
Journal: Mol Cell Biol
Title: Absence of an essential role for thymic stromal lymphopoietin receptor in murine B-cell development.
Volume: 24
Issue: 6
Pages: 2584-92
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Publication
28258089 | J:241513
First Author: Zhang X
Year: 2017
Journal: J Lipid Res
Title: Oncostatin M receptor β deficiency attenuates atherogenesis by inhibiting JAK2/STAT3 signaling in macrophages.
Volume: 58
Issue: 5
Pages: 895-906
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Publication
18162139 | J:133411
First Author: Dogan S
Year: 2007
Journal: Breast Cancer Res
Title: Effects of high-fat diet and/or body weight on mammary tumor leptin and apoptosis signaling pathways in MMTV-TGF-alpha mice.
Volume: 9
Issue: 6
Pages: R91
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Publication
39560988 | J:361438
 
First Author: Leonard MR
Year: 2024
Journal: JCI Insight
Title: Aiolos promotes CXCR3 expression on Th1 cells via positive regulation of IFN-γ/STAT1 signaling.
Volume: 10
Issue: 1
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Publication
33372035 | J:302977
 
First Author: Karki P
Year: 2021
Journal: J Biol Chem
Title: SOCS3-microtubule interaction via CLIP-170 and CLASP2 is critical for modulation of endothelial inflammation and lung injury.
Volume: 296
Pages: 100239
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Publication
17235396 | J:118030
First Author: Ren D
Year: 2007
Journal: J Clin Invest
Title: Neuronal SH2B1 is essential for controlling energy and glucose homeostasis.
Volume: 117
Issue: 2
Pages: 397-406
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18716208 | J:138835
First Author: Zearfoss NR
Year: 2008
Journal: J Neurosci
Title: A molecular circuit composed of CPEB-1 and c-Jun controls growth hormone-mediated synaptic plasticity in the mouse hippocampus.
Volume: 28
Issue: 34
Pages: 8502-9
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Publication
24008317 | J:202756
First Author: Vindrieux D
Year: 2013
Journal: Cancer Res
Title: PLA2R1 mediates tumor suppression by activating JAK2.
Volume: 73
Issue: 20
Pages: 6334-45
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Publication
25468568 | J:221386
First Author: Bender M
Year: 2015
Journal: Blood
Title: Dynamin 2-dependent endocytosis is required for normal megakaryocyte development in mice.
Volume: 125
Issue: 6
Pages: 1014-24
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Publication
30728366 | J:307441
First Author: Moore SF
Year: 2019
Journal: Sci Rep
Title: Critical roles for the phosphatidylinositide 3-kinase isoforms p110β and p110γ in thrombopoietin-mediated priming of platelet function.
Volume: 9
Issue: 1
Pages: 1468
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Publication
31750881 | J:285074
First Author: Yue L
Year: 2020
Journal: Blood
Title: HDAC11 deficiency disrupts oncogene-induced hematopoiesis in myeloproliferative neoplasms.
Volume: 135
Issue: 3
Pages: 191-207
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Publication
25070848 | J:317662
First Author: Beswick EJ
Year: 2014
Journal: J Immunol
Title: TLR4 activation enhances the PD-L1-mediated tolerogenic capacity of colonic CD90+ stromal cells.
Volume: 193
Issue: 5
Pages: 2218-29
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Publication
32149730 | J:302653
First Author: Gracey E
Year: 2020
Journal: J Clin Invest
Title: TYK2 inhibition reduces type 3 immunity and modifies disease progression in murine spondyloarthritis.
Volume: 130
Issue: 4
Pages: 1863-1878
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Publication
27561547 | J:283031
 
First Author: Guo L
Year: 2016
Journal: Sci Rep
Title: Cell non-autonomous regulation of hepatic IGF-1 and neonatal growth by Kinase Suppressor of Ras 2 (KSR2).
Volume: 6
Pages: 32093
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Publication
10845925 | J:166206
First Author: Carron C
Year: 2000
Journal: Blood
Title: TEL-JAK2 transgenic mice develop T-cell leukemia.
Volume: 95
Issue: 12
Pages: 3891-9
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Publication
15578097 | J:95477
First Author: Stoiber D
Year: 2004
Journal: J Clin Invest
Title: TYK2 is a key regulator of the surveillance of B lymphoid tumors.
Volume: 114
Issue: 11
Pages: 1650-8
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Publication
35051265 | J:334059
First Author: Bennett C
Year: 2022
Journal: Blood
Title: CRLF3 plays a key role in the final stage of platelet genesis and is a potential therapeutic target for thrombocythemia.
Volume: 139
Issue: 14
Pages: 2227-2239
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Publication
32661325 | J:297893
First Author: Toda J
Year: 2020
Journal: Oncogene
Title: Signal-transducing adapter protein-1 is required for maintenance of leukemic stem cells in CML.
Volume: 39
Issue: 34
Pages: 5601-5615
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Publication
8702683 | J:34907
First Author: Xu BC
Year: 1996
Journal: J Biol Chem
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