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Search results 901 to 1000 out of 2308 for Lep

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Type Details Score
Publication
39187042 | J:355016
First Author: Wang Y
Year: 2024
Journal: J Lipid Res
Title: Therapeutic siRNA targeting PLIN2 ameliorates steatosis, inflammation, and fibrosis in steatotic liver disease models.
Volume: 65
Issue: 10
Pages: 100635
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Publication
17003333 | J:116580
First Author: Lijnen HR
Year: 2006
Journal: Diabetes
Title: Impaired adipose tissue development in mice with inactivation of placental growth factor function.
Volume: 55
Issue: 10
Pages: 2698-704
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Publication
25370851 | J:218529
First Author: Rulifson IC
Year: 2014
Journal: Am J Physiol Endocrinol Metab
Title: Inhibition of secreted frizzled-related protein 5 improves glucose metabolism.
Volume: 307
Issue: 12
Pages: E1144-52
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Publication
21270263 | J:169785
First Author: Koenen TB
Year: 2011
Journal: Diabetes
Title: Hyperglycemia activates caspase-1 and TXNIP-mediated IL-1beta transcription in human adipose tissue.
Volume: 60
Issue: 2
Pages: 517-24
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Publication
28698385 | J:246042
First Author: Liu Y
Year: 2017
Journal: J Biol Chem
Title: Retinoic acid receptor-related orphan receptor α stimulates adipose tissue inflammation by modulating endoplasmic reticulum stress.
Volume: 292
Issue: 34
Pages: 13959-13969
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Publication
32603429 | J:295989
 
First Author: Fu Y
Year: 2020
Journal: Endocrinology
Title: Gut Hormone GIP Induces Inflammation and Insulin Resistance in the Hypothalamus.
Volume: 161
Issue: 9
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Publication
24123166 | J:347377
First Author: Wang XA
Year: 2014
Journal: Hepatology
Title: Interferon regulatory factor 3 constrains IKKβ/NF-κB signaling to alleviate hepatic steatosis and insulin resistance.
Volume: 59
Issue: 3
Pages: 870-85
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Publication
22541436 | J:186193
First Author: Grueter CE
Year: 2012
Journal: Cell
Title: A cardiac microRNA governs systemic energy homeostasis by regulation of MED13.
Volume: 149
Issue: 3
Pages: 671-83
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Publication
28844948 | J:253886
First Author: Li J
Year: 2017
Journal: Biochim Biophys Acta
Title: Inhibition of insulin/PI3K/AKT signaling decreases adipose Sortilin 1 in mice and 3T3-L1 adipocytes.
Volume: 1863
Issue: 11
Pages: 2924-2933
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Publication
28096235 | J:274525
First Author: López-Yoldi M
Year: 2017
Journal: FASEB J
Title: Role of cardiotrophin-1 in the regulation of metabolic circadian rhythms and adipose core clock genes in mice and characterization of 24-h circulating CT-1 profiles in normal-weight and overweight/obese subjects.
Volume: 31
Issue: 4
Pages: 1639-1649
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Publication
26527067 | J:230841
First Author: Pisani DF
Year: 2016
Journal: FASEB J
Title: The K+ channel TASK1 modulates β-adrenergic response in brown adipose tissue through the mineralocorticoid receptor pathway.
Volume: 30
Issue: 2
Pages: 909-22
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Publication
29208957 | J:257771
First Author: Yamamoto J
Year: 2017
Journal: Nat Commun
Title: Neuronal signals regulate obesity induced β-cell proliferation by FoxM1 dependent mechanism.
Volume: 8
Issue: 1
Pages: 1930
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Publication
21576825 | J:173902
First Author: Bezy O
Year: 2011
Journal: J Clin Invest
Title: PKCδ regulates hepatic insulin sensitivity and hepatosteatosis in mice and humans.
Volume: 121
Issue: 6
Pages: 2504-17
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Publication
25255859 | J:274570
 
First Author: Lim YM
Year: 2014
Journal: Nat Commun
Title: Systemic autophagy insufficiency compromises adaptation to metabolic stress and facilitates progression from obesity to diabetes.
Volume: 5
Pages: 4934
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Publication
23471885 | J:310033
First Author: Wang XA
Year: 2013
Journal: Hepatology
Title: Interferon regulatory factor 9 protects against hepatic insulin resistance and steatosis in male mice.
Volume: 58
Issue: 2
Pages: 603-16
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Publication
24374218 | J:210550
First Author: Amano SU
Year: 2014
Journal: Cell Metab
Title: Local proliferation of macrophages contributes to obesity-associated adipose tissue inflammation.
Volume: 19
Issue: 1
Pages: 162-171
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Publication
27544029 | J:238937
First Author: Li R
Year: 2016
Journal: Biochem Biophys Res Commun
Title: Metformin ameliorates obesity-associated hypertriglyceridemia in mice partly through the apolipoprotein A5 pathway.
Volume: 478
Issue: 3
Pages: 1173-8
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Publication
30340828 | J:270747
First Author: Wang YM
Year: 2018
Journal: Biochem Biophys Res Commun
Title: 9-PAHSA promotes browning of white fat via activating G-protein-coupled receptor 120 and inhibiting lipopolysaccharide / NF-kappa B pathway.
Volume: 506
Issue: 1
Pages: 153-160
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Publication
27520373 | J:238957
First Author: Baldini SF
Year: 2016
Journal: Biochem Biophys Res Commun
Title: Glucokinase expression is regulated by glucose through O-GlcNAc glycosylation.
Volume: 478
Issue: 2
Pages: 942-8
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Publication
25337938 | J:222449
First Author: Patsouris D
Year: 2014
Journal: PLoS One
Title: Insulin resistance is associated with MCP1-mediated macrophage accumulation in skeletal muscle in mice and humans.
Volume: 9
Issue: 10
Pages: e110653
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Publication
27064285 | J:234937
First Author: Dai C
Year: 2016
Journal: J Clin Invest
Title: Stress-impaired transcription factor expression and insulin secretion in transplanted human islets.
Volume: 126
Issue: 5
Pages: 1857-70
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Publication
20953578 | J:165782
First Author: Jager J
Year: 2011
Journal: Diabetologia
Title: Deficiency in the extracellular signal-regulated kinase 1 (ERK1) protects leptin-deficient mice from insulin resistance without affecting obesity.
Volume: 54
Issue: 1
Pages: 180-9
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Publication
7784267 | J:24888
First Author: Evans AA
Year: 1995
Journal: Peptides
Title: Delta-opioid peptide receptors in muscles from obese diabetic and normal mice.
Volume: 16
Issue: 2
Pages: 361-4
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23904453 | J:202622
First Author: Bi L
Year: 2013
Journal: J Lipid Res
Title: Saturated fatty acids activate ERK signaling to downregulate hepatic sortilin 1 in obese and diabetic mice.
Volume: 54
Issue: 10
Pages: 2754-62
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Publication
36535401 | J:334684
 
First Author: Shintani T
Year: 2023
Journal: Life Sci
Title: Deletion or inhibition of PTPRO prevents ectopic fat accumulation and induces healthy obesity with markedly reduced systemic inflammation.
Volume: 313
Pages: 121292
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Publication
23178931 | J:194636
First Author: Panzhinskiy E
Year: 2013
Journal: Diabetologia
Title: Endoplasmic reticulum stress upregulates protein tyrosine phosphatase 1B and impairs glucose uptake in cultured myotubes.
Volume: 56
Issue: 3
Pages: 598-607
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Publication
29750244 | J:262946
First Author: Maier MT
Year: 2018
Journal: Endocrinology
Title: Regulation of Hepatic Lipid Accumulation and Distribution by Agouti-Related Protein in Male Mice.
Volume: 159
Issue: 6
Pages: 2408-2420
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Publication
26529285 | J:256822
First Author: Coombes JD
Year: 2016
Journal: Biochim Biophys Acta
Title: Osteopontin is a proximal effector of leptin-mediated non-alcoholic steatohepatitis (NASH) fibrosis.
Volume: 1862
Issue: 1
Pages: 135-44
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Publication
25236782 | J:288016
 
First Author: Tanaka M
Year: 2014
Journal: Nat Commun
Title: Macrophage-inducible C-type lectin underlies obesity-induced adipose tissue fibrosis.
Volume: 5
Pages: 4982
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Publication
16809344 | J:116947
First Author: Kamei N
Year: 2006
Journal: J Biol Chem
Title: Overexpression of monocyte chemoattractant protein-1 in adipose tissues causes macrophage recruitment and insulin resistance.
Volume: 281
Issue: 36
Pages: 26602-14
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Publication
10965911 | J:108811
First Author: Uysal KT
Year: 2000
Journal: Endocrinology
Title: Improved glucose and lipid metabolism in genetically obese mice lacking aP2.
Volume: 141
Issue: 9
Pages: 3388-96
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Publication
34954499 | J:321661
 
First Author: Yuan J
Year: 2022
Journal: Redox Biol
Title: Inhibition of GCN2 alleviates hepatic steatosis and oxidative stress in obese mice: Involvement of NRF2 regulation.
Volume: 49
Pages: 102224
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Publication
212501 | J:6045
First Author: Ruddle NH
Year: 1978
Journal: J Exp Med
Title: Assignment of the receptor for ecotropic murine leukemia virus to mouse chromosome 5.
Volume: 148
Issue: 2
Pages: 451-65
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Publication
33324349 | J:311676
 
First Author: Ferreira SM
Year: 2020
Journal: Front Endocrinol (Lausanne)
Title: ARHGAP21 Acts as an Inhibitor of the Glucose-Stimulated Insulin Secretion Process.
Volume: 11
Pages: 599165
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Publication
31346174 | J:279450
First Author: Pasquier A
Year: 2019
Journal: Nat Commun
Title: Lysosomal degradation of newly formed insulin granules contributes to β cell failure in diabetes.
Volume: 10
Issue: 1
Pages: 3312
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Publication
22628617 | J:186560
First Author: Wang CY
Year: 2012
Journal: J Lipid Res
Title: Tsc2, a positional candidate gene underlying a quantitative trait locus for hepatic steatosis.
Volume: 53
Issue: 8
Pages: 1493-501
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Publication
15369800 | J:92476
First Author: Rondinone CM
Year: 2004
Journal: Biochem Biophys Res Commun
Title: Reduction of PTP1B induces differential expression of PI3-kinase (p85alpha) isoforms.
Volume: 323
Issue: 2
Pages: 652-9
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Publication
19114551 | J:145762
First Author: Khan T
Year: 2009
Journal: Mol Cell Biol
Title: Metabolic dysregulation and adipose tissue fibrosis: role of collagen VI.
Volume: 29
Issue: 6
Pages: 1575-91
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Publication
23185367 | J:194789
First Author: Mu J
Year: 2012
Journal: PLoS One
Title: Anti-diabetic efficacy and impact on amino acid metabolism of GRA1, a novel small-molecule glucagon receptor antagonist.
Volume: 7
Issue: 11
Pages: e49572
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Publication
26256903 | J:324512
First Author: Sutter AG
Year: 2015
Journal: Ann Hepatol
Title: Development of steatohepatitis in Ob/Ob mice is dependent on Toll-like receptor 4.
Volume: 14
Issue: 5
Pages: 735-43
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14551222 | J:96671
First Author: Albarado DC
Year: 2004
Journal: Endocrinology
Title: Impaired coordination of nutrient intake and substrate oxidation in melanocortin-4 receptor knockout mice.
Volume: 145
Issue: 1
Pages: 243-52
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Publication
21437772 | J:170306
First Author: Meissburger B
Year: 2011
Journal: Diabetologia
Title: Tissue inhibitor of matrix metalloproteinase 1 (TIMP1) controls adipogenesis in obesity in mice and in humans.
Volume: 54
Issue: 6
Pages: 1468-79
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Publication
33691105 | J:304292
First Author: Alvarez-Guaita A
Year: 2021
Journal: Cell Rep
Title: Phenotypic characterization of Adig null mice suggests roles for adipogenin in the regulation of fat mass accrual and leptin secretion.
Volume: 34
Issue: 10
Pages: 108810
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Publication
17643114 | J:129484
First Author: Yang M
Year: 2007
Journal: Nat Cell Biol
Title: Cathepsin L activity controls adipogenesis and glucose tolerance.
Volume: 9
Issue: 8
Pages: 970-7
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27214655 | J:337647
First Author: Kim GW
Year: 2016
Journal: Nutr Diabetes
Title: Calorie-induced ER stress suppresses uroguanylin satiety signaling in diet-induced obesity.
Volume: 6
Issue: 5
Pages: e211
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Publication
24038081 | J:275838
First Author: Kim SC
Year: 2014
Journal: Hepatology
Title: All-trans-retinoic acid ameliorates hepatic steatosis in mice by a novel transcriptional cascade.
Volume: 59
Issue: 5
Pages: 1750-60
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Publication
32439965 | J:292058
First Author: Locatelli M
Year: 2020
Journal: Sci Rep
Title: Manipulating Sirtuin 3 pathway ameliorates renal damage in experimental diabetes.
Volume: 10
Issue: 1
Pages: 8418
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Publication
25144618 | J:219118
First Author: Ikels K
Year: 2014
Journal: PLoS One
Title: FTO is a relevant factor for the development of the metabolic syndrome in mice.
Volume: 9
Issue: 8
Pages: e105349
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Publication
25391656 | J:302802
First Author: Filios SR
Year: 2014
Journal: J Biol Chem
Title: MicroRNA-200 is induced by thioredoxin-interacting protein and regulates Zeb1 protein signaling and beta cell apoptosis.
Volume: 289
Issue: 52
Pages: 36275-83
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Publication
23640861 | J:206893
First Author: Seth RK
Year: 2013
Journal: Toxicol Sci
Title: Environmental toxin-linked nonalcoholic steatohepatitis and hepatic metabolic reprogramming in obese mice.
Volume: 134
Issue: 2
Pages: 291-303
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Publication
25968479 | J:325868
First Author: Lizarbe B
Year: 2015
Journal: Neurochem Res
Title: fDWI Evaluation of Hypothalamic Appetite Regulation Pathways in Mice Genetically Deficient in Leptin or Neuropeptide Y.
Volume: 40
Issue: 12
Pages: 2628-38
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Publication
35917179 | J:335840
 
First Author: Hwang E
Year: 2022
Journal: JCI Insight
Title: Sustained inhibition of NPY/AgRP neuronal activity by FGF1.
Volume: 7
Issue: 17
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Publication
30865891 | J:282319
First Author: Kluth O
Year: 2019
Journal: Cell Rep
Title: Decreased Expression of Cilia Genes in Pancreatic Islets as a Risk Factor for Type 2 Diabetes in Mice and Humans.
Volume: 26
Issue: 11
Pages: 3027-3036.e3
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Publication
15306821 | J:92663
First Author: Um SH
Year: 2004
Journal: Nature
Title: Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity.
Volume: 431
Issue: 7005
Pages: 200-5
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Publication
29596828 | J:270166
First Author: Liao MJ
Year: 2018
Journal: Biochem Biophys Res Commun
Title: NFATc3 deficiency protects against high fat diet (HFD)-induced hypothalamus inflammation and apoptosis via p38 and JNK suppression.
Volume: 499
Issue: 4
Pages: 743-750
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Publication
23562077 | J:198973
First Author: Mansuy-Aubert V
Year: 2013
Journal: Cell Metab
Title: Imbalance between neutrophil elastase and its inhibitor α1-antitrypsin in obesity alters insulin sensitivity, inflammation, and energy expenditure.
Volume: 17
Issue: 4
Pages: 534-48
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Publication
16469807 | J:129662
First Author: Ukropec J
Year: 2006
Journal: Endocrinology
Title: Leptin is required for uncoupling protein-1-independent thermogenesis during cold stress.
Volume: 147
Issue: 5
Pages: 2468-80
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Publication
11970899 | J:75969
First Author: Cheng A
Year: 2002
Journal: Dev Cell
Title: Attenuation of leptin action and regulation of obesity by protein tyrosine phosphatase 1B.
Volume: 2
Issue: 4
Pages: 497-503
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22395110 | J:186860
First Author: Bie J
Year: 2012
Journal: Am J Physiol Endocrinol Metab
Title: Macrophage-specific transgenic expression of cholesteryl ester hydrolase attenuates hepatic lipid accumulation and also improves glucose tolerance in ob/ob mice.
Volume: 302
Issue: 10
Pages: E1283-91
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Publication
19513120 | J:150201
First Author: Deveaux V
Year: 2009
Journal: PLoS One
Title: Cannabinoid CB2 receptor potentiates obesity-associated inflammation, insulin resistance and hepatic steatosis.
Volume: 4
Issue: 6
Pages: e5844
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Publication
28297678 | J:254556
First Author: Miyachi Y
Year: 2017
Journal: Cell Rep
Title: Roles for Cell-Cell Adhesion and Contact in Obesity-Induced Hepatic Myeloid Cell Accumulation and Glucose Intolerance.
Volume: 18
Issue: 11
Pages: 2766-2779
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Publication
33833312 | J:313764
First Author: Sandovici I
Year: 2021
Journal: Sci Rep
Title: Autocrine IGF2 programmes β-cell plasticity under conditions of increased metabolic demand.
Volume: 11
Issue: 1
Pages: 7717
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Publication
27793638 | J:259162
 
First Author: Gratuze M
Year: 2017
Journal: Neurobiol Dis
Title: Tau hyperphosphorylation in the brain of ob/ob mice is due to hypothermia: Importance of thermoregulation in linking diabetes and Alzheimer's disease.
Volume: 98
Pages: 1-8
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Publication
27075628 | J:246223
First Author: Ribas V
Year: 2016
Journal: Sci Transl Med
Title: Skeletal muscle action of estrogen receptor α is critical for the maintenance of mitochondrial function and metabolic homeostasis in females.
Volume: 8
Issue: 334
Pages: 334ra54
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Publication
17084710 | J:129745
First Author: Gautam D
Year: 2006
Journal: Cell Metab
Title: Beneficial metabolic effects of M3 muscarinic acetylcholine receptor deficiency.
Volume: 4
Issue: 5
Pages: 363-75
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35977541 | J:329297
First Author: Xue K
Year: 2022
Journal: Cell Metab
Title: The mitochondrial calcium uniporter engages UCP1 to form a thermoporter that promotes thermogenesis.
Volume: 34
Issue: 9
Pages: 1325-1341.e6
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15001430 | J:109323
First Author: Guo KY
Year: 2004
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Effects of obesity on the relationship of leptin mRNA expression and adipocyte size in anatomically distinct fat depots in mice.
Volume: 287
Issue: 1
Pages: R112-9
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Publication
25333972 | J:223438
First Author: Chung JJ
Year: 2014
Journal: PLoS One
Title: Role of NKG2D in obesity-induced adipose tissue inflammation and insulin resistance.
Volume: 9
Issue: 10
Pages: e110108
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Publication
20660304 | J:182843
First Author: Davis DB
Year: 2010
Journal: Mol Endocrinol
Title: FoxM1 is up-regulated by obesity and stimulates beta-cell proliferation.
Volume: 24
Issue: 9
Pages: 1822-34
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Publication
24155240 | J:207207
First Author: Pessentheiner AR
Year: 2013
Journal: J Biol Chem
Title: NAT8L (N-acetyltransferase 8-like) accelerates lipid turnover and increases energy expenditure in brown adipocytes.
Volume: 288
Issue: 50
Pages: 36040-51
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17379835 | J:133901
First Author: Bäck M
Year: 2007
Journal: Circ Res
Title: 5-Lipoxygenase-activating protein: a potential link between innate and adaptive immunity in atherosclerosis and adipose tissue inflammation.
Volume: 100
Issue: 7
Pages: 946-9
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Publication
37318951 | J:338368
First Author: Pellegrinelli V
Year: 2023
Journal: Cell Rep
Title: Defective extracellular matrix remodeling in brown adipose tissue is associated with fibro-inflammation and reduced diet-induced thermogenesis.
Volume: 42
Issue: 6
Pages: 112640
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Publication
22474027 | J:203177
First Author: Kitade H
Year: 2012
Journal: Diabetes
Title: CCR5 plays a critical role in obesity-induced adipose tissue inflammation and insulin resistance by regulating both macrophage recruitment and M1/M2 status.
Volume: 61
Issue: 7
Pages: 1680-90
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Publication
32900697 | J:308014
 
First Author: Opazo-Ríos L
Year: 2020
Journal: BMJ Open Diabetes Res Care
Title: Anti-inflammatory, antioxidant and renoprotective effects of SOCS1 mimetic peptide in the BTBR ob/ob mouse model of type 2 diabetes.
Volume: 8
Issue: 1
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23695216 | J:203226
First Author: Wang XA
Year: 2013
Journal: Am J Physiol Endocrinol Metab
Title: Interferon regulatory factor 7 deficiency prevents diet-induced obesity and insulin resistance.
Volume: 305
Issue: 4
Pages: E485-95
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Publication
22719268 | J:187067
First Author: Pan D
Year: 2012
Journal: PLoS Genet
Title: The histone demethylase Jhdm1a regulates hepatic gluconeogenesis.
Volume: 8
Issue: 6
Pages: e1002761
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Publication
24639549 | J:207292
First Author: Pang Z
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Therapeutic vaccine against DPP4 improves glucose metabolism in mice.
Volume: 111
Issue: 13
Pages: E1256-63
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36702623 | J:355409
 
First Author: Dassie F
Year: 2023
Journal: Endocrinology
Title: Hematopoietic Stem Cells and Metabolic Deterioration in Alström Syndrome, a Rare Genetic Model of the Metabolic Syndrome.
Volume: 164
Issue: 3
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Publication
19651818 | J:154387
First Author: Latham JR
Year: 2009
Journal: Diabetes
Title: Selective T-type calcium channel blockade alleviates hyperalgesia in ob/ob mice.
Volume: 58
Issue: 11
Pages: 2656-65
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Publication
24519936 | J:326410
First Author: Shi L
Year: 2014
Journal: J Biol Chem
Title: Sustained high protein-tyrosine phosphatase 1B activity in the sperm of obese males impairs the sperm acrosome reaction.
Volume: 289
Issue: 12
Pages: 8432-41
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Publication
29056532 | J:263344
 
First Author: Liao X
Year: 2018
Journal: Mol Cell Endocrinol
Title: LAMP3 regulates hepatic lipid metabolism through activating PI3K/Akt pathway.
Volume: 470
Pages: 160-167
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Publication
24680679 | J:219470
First Author: Xu A
Year: 2014
Journal: Biochem Biophys Res Commun
Title: Mitochondrial translocation of Nur77 induced by ROS contributed to cardiomyocyte apoptosis in metabolic syndrome.
Volume: 446
Issue: 4
Pages: 1184-9
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Publication
20624962 | J:162570
First Author: Ranieri SC
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Mammalian life-span determinant p66shcA mediates obesity-induced insulin resistance.
Volume: 107
Issue: 30
Pages: 13420-5
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Publication
32709874 | J:292279
First Author: Toubal A
Year: 2020
Journal: Nat Commun
Title: Mucosal-associated invariant T cells promote inflammation and intestinal dysbiosis leading to metabolic dysfunction during obesity.
Volume: 11
Issue: 1
Pages: 3755
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Publication
26625958 | J:227694
First Author: Pan D
Year: 2015
Journal: Dev Cell
Title: Jmjd3-Mediated H3K27me3 Dynamics Orchestrate Brown Fat Development and Regulate White Fat Plasticity.
Volume: 35
Issue: 5
Pages: 568-83
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