Type |
Details |
Score |
Publication |
First Author: |
Baek JA |
Year: |
2011 |
Journal: |
Dev Biol |
Title: |
Bmpr1a signaling plays critical roles in palatal shelf growth and palatal bone formation. |
Volume: |
350 |
Issue: |
2 |
Pages: |
520-31 |
|
•
•
•
•
•
|
Publication |
First Author: |
Huang X |
Year: |
2008 |
Journal: |
PLoS Biol |
Title: |
Inhibitory phosphorylation of separase is essential for genome stability and viability of murine embryonic germ cells. |
Volume: |
6 |
Issue: |
1 |
Pages: |
e15 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dinsmore CJ |
Year: |
2022 |
Journal: |
Elife |
Title: |
Differential regulation of cranial and cardiac neural crest by serum response factor and its cofactors. |
Volume: |
11 |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Guimarães-Camboa N |
Year: |
2015 |
Journal: |
Dev Cell |
Title: |
HIF1α Represses Cell Stress Pathways to Allow Proliferation of Hypoxic Fetal Cardiomyocytes. |
Volume: |
33 |
Issue: |
5 |
Pages: |
507-21 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lu CC |
Year: |
2004 |
Journal: |
Dev Biol |
Title: |
Multiple roles for Nodal in the epiblast of the mouse embryo in the establishment of anterior-posterior patterning. |
Volume: |
273 |
Issue: |
1 |
Pages: |
149-59 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rocque BL |
Year: |
2015 |
Journal: |
J Am Soc Nephrol |
Title: |
Deficiency of the planar cell polarity protein Vangl2 in podocytes affects glomerular morphogenesis and increases susceptibility to injury. |
Volume: |
26 |
Issue: |
3 |
Pages: |
576-86 |
|
•
•
•
•
•
|
Publication |
First Author: |
Murray SA |
Year: |
2006 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Snail family genes are required for left-right asymmetry determination, but not neural crest formation, in mice. |
Volume: |
103 |
Issue: |
27 |
Pages: |
10300-4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Vinagre T |
Year: |
2010 |
Journal: |
Dev Cell |
Title: |
Evidence for a myotomal Hox/Myf cascade governing nonautonomous control of rib specification within global vertebral domains. |
Volume: |
18 |
Issue: |
4 |
Pages: |
655-61 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kuta A |
Year: |
2016 |
Journal: |
Development |
Title: |
Fat4-Dchs1 signalling controls cell proliferation in developing vertebrae. |
Volume: |
143 |
Issue: |
13 |
Pages: |
2367-75 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rumballe BA |
Year: |
2011 |
Journal: |
Dev Biol |
Title: |
Nephron formation adopts a novel spatial topology at cessation of nephrogenesis. |
Volume: |
360 |
Issue: |
1 |
Pages: |
110-22 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rowton M |
Year: |
2013 |
Journal: |
Dev Dyn |
Title: |
Regulation of mesenchymal-to-epithelial transition by PARAXIS during somitogenesis. |
Volume: |
242 |
Issue: |
11 |
Pages: |
1332-44 |
|
•
•
•
•
•
|
Publication |
First Author: |
Anderson C |
Year: |
2012 |
Journal: |
Genes Dev |
Title: |
Sonic hedgehog acts cell-autonomously on muscle precursor cells to generate limb muscle diversity. |
Volume: |
26 |
Issue: |
18 |
Pages: |
2103-17 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lee Y |
Year: |
2012 |
Journal: |
EMBO J |
Title: |
ATR maintains select progenitors during nervous system development. |
Volume: |
31 |
Issue: |
5 |
Pages: |
1177-89 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lee Y |
Year: |
2009 |
Journal: |
Nat Neurosci |
Title: |
The genesis of cerebellar interneurons and the prevention of neural DNA damage require XRCC1. |
Volume: |
12 |
Issue: |
8 |
Pages: |
973-80 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ray AT |
Year: |
2020 |
Journal: |
Genes Dev |
Title: |
FGF signaling regulates development by processes beyond canonical pathways. |
Volume: |
34 |
Issue: |
23-24 |
Pages: |
1735-1752 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fossat N |
Year: |
2015 |
Journal: |
Development |
Title: |
Context-specific function of the LIM homeobox 1 transcription factor in head formation of the mouse embryo. |
Volume: |
142 |
Issue: |
11 |
Pages: |
2069-79 |
|
•
•
•
•
•
|
Publication |
First Author: |
Grote D |
Year: |
2006 |
Journal: |
Development |
Title: |
Pax 2/8-regulated Gata 3 expression is necessary for morphogenesis and guidance of the nephric duct in the developing kidney. |
Volume: |
133 |
Issue: |
1 |
Pages: |
53-61 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lin C |
Year: |
2011 |
Journal: |
Dev Biol |
Title: |
The inductive role of Wnt-β-Catenin signaling in the formation of oral apparatus. |
Volume: |
356 |
Issue: |
1 |
Pages: |
40-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fairchild CL |
Year: |
2018 |
Journal: |
Development |
Title: |
RBX2 maintains final retinal cell position in a DAB1-dependent and -independent fashion. |
Volume: |
145 |
Issue: |
3 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Patterson ES |
Year: |
2014 |
Journal: |
Dev Biol |
Title: |
Geminin loss causes neural tube defects through disrupted progenitor specification and neuronal differentiation. |
Volume: |
393 |
Issue: |
1 |
Pages: |
44-56 |
|
•
•
•
•
•
|
Publication |
First Author: |
Funato N |
Year: |
2012 |
Journal: |
Hum Mol Genet |
Title: |
Tbx1 regulates oral epithelial adhesion and palatal development. |
Volume: |
21 |
Issue: |
11 |
Pages: |
2524-37 |
|
•
•
•
•
•
|
Publication |
First Author: |
López-Tello J |
Year: |
2019 |
Journal: |
Elife |
Title: |
Fetal and trophoblast PI3K p110α have distinct roles in regulating resource supply to the growing fetus in mice. |
Volume: |
8 |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bolt CC |
Year: |
2016 |
Journal: |
PLoS One |
Title: |
Tbx18 Regulates the Differentiation of Periductal Smooth Muscle Stroma and the Maintenance of Epithelial Integrity in the Prostate. |
Volume: |
11 |
Issue: |
4 |
Pages: |
e0154413 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sandovici I |
Year: |
2022 |
Journal: |
Dev Cell |
Title: |
The imprinted Igf2-Igf2r axis is critical for matching placental microvasculature expansion to fetal growth. |
Volume: |
57 |
Issue: |
1 |
Pages: |
63-79.e8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Funato N |
Year: |
2018 |
Journal: |
Arch Oral Biol |
Title: |
Deletion of the T-box transcription factor gene, Tbx1, in mice induces differential expression of genes associated with cleft palate in humans. |
Volume: |
95 |
|
Pages: |
149-155 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fantauzzo KA |
Year: |
2016 |
Journal: |
Genes Dev |
Title: |
PDGFRβ regulates craniofacial development through homodimers and functional heterodimers with PDGFRα. |
Volume: |
30 |
Issue: |
21 |
Pages: |
2443-2458 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hirai M |
Year: |
2017 |
Journal: |
J Clin Invest |
Title: |
Adaptor proteins NUMB and NUMBL promote cell cycle withdrawal by targeting ERBB2 for degradation. |
Volume: |
127 |
Issue: |
2 |
Pages: |
569-582 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ackermann J |
Year: |
2011 |
Journal: |
PLoS One |
Title: |
Loss of ATF2 function leads to cranial motoneuron degeneration during embryonic mouse development. |
Volume: |
6 |
Issue: |
4 |
Pages: |
e19090 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cattaneo P |
Year: |
2022 |
Journal: |
Nat Commun |
Title: |
DOT1L regulates chamber-specific transcriptional networks during cardiogenesis and mediates postnatal cell cycle withdrawal. |
Volume: |
13 |
Issue: |
1 |
Pages: |
7444 |
|
•
•
•
•
•
|
Publication |
First Author: |
Clark JF |
Year: |
2024 |
Journal: |
Genes Dev |
Title: |
Diverse Fgfr1 signaling pathways and endocytic trafficking regulate mesoderm development. |
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|
•
•
•
•
•
|
Publication |
First Author: |
Perea-Gomez A |
Year: |
2019 |
Journal: |
Sci Rep |
Title: |
Loss of Cubilin, the intrinsic factor-vitamin B12 receptor, impairs visceral endoderm endocytosis and endodermal patterning in the mouse. |
Volume: |
9 |
Issue: |
1 |
Pages: |
10168 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu TY |
Year: |
2017 |
Journal: |
Open Biol |
Title: |
Muscle developmental defects in heterogeneous nuclear Ribonucleoprotein A1 knockout mice. |
Volume: |
7 |
Issue: |
1 |
|
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•
•
•
•
•
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Publication |
First Author: |
Dias A |
Year: |
2020 |
Journal: |
Elife |
Title: |
A Tgfbr1/Snai1-dependent developmental module at the core of vertebrate axial elongation. |
Volume: |
9 |
|
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•
•
•
•
•
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Publication |
First Author: |
Mugford JW |
Year: |
2009 |
Journal: |
Dev Biol |
Title: |
High-resolution gene expression analysis of the developing mouse kidney defines novel cellular compartments within the nephron progenitor population. |
Volume: |
333 |
Issue: |
2 |
Pages: |
312-23 |
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•
•
•
•
•
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Publication |
First Author: |
Reginensi A |
Year: |
2013 |
Journal: |
PLoS Genet |
Title: |
Yap- and Cdc42-dependent nephrogenesis and morphogenesis during mouse kidney development. |
Volume: |
9 |
Issue: |
3 |
Pages: |
e1003380 |
|
•
•
•
•
•
|
Publication |
First Author: |
Basta JM |
Year: |
2014 |
Journal: |
Development |
Title: |
Sall1 balances self-renewal and differentiation of renal progenitor cells. |
Volume: |
141 |
Issue: |
5 |
Pages: |
1047-58 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shanghai Model Organisms Center |
Year: |
2017 |
Journal: |
MGI Direct Data Submission |
Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
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•
•
•
•
•
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Publication |
First Author: |
Shimizu H |
Year: |
2013 |
Journal: |
PLoS One |
Title: |
The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo. |
Volume: |
8 |
Issue: |
10 |
Pages: |
e75754 |
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•
•
•
•
•
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Publication |
First Author: |
Chung YC |
Year: |
2011 |
Journal: |
Gene Expr Patterns |
Title: |
Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus. |
Volume: |
11 |
Issue: |
1-2 |
Pages: |
84-92 |
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•
•
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•
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Publication |
First Author: |
Wiese CB |
Year: |
2012 |
Journal: |
Front Neurosci |
Title: |
A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract. |
Volume: |
6 |
|
Pages: |
130 |
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•
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•
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Publication |
First Author: |
International Committee on Standardized Genetic Nomenclature for Mice |
Year: |
1993 |
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Title: |
Nomenclature rule change to delete hyphens and parentheses from mouse locus symbols |
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•
•
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Publication |
First Author: |
Yokoyama S |
Year: |
2009 |
Journal: |
Dev Cell |
Title: |
A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. |
Volume: |
17 |
Issue: |
6 |
Pages: |
836-48 |
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•
•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2001 |
|
Title: |
Gene Ontology Annotation by the MGI Curatorial Staff |
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•
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Publication |
First Author: |
Gray PA |
Year: |
2004 |
Journal: |
Science |
Title: |
Mouse brain organization revealed through direct genome-scale TF expression analysis. |
Volume: |
306 |
Issue: |
5705 |
Pages: |
2255-7 |
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Publication |
First Author: |
Thompson CL |
Year: |
2014 |
Journal: |
Neuron |
Title: |
A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. |
Volume: |
83 |
Issue: |
2 |
Pages: |
309-323 |
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Publication |
First Author: |
Lennon G |
Year: |
1999 |
Journal: |
Database Download |
Title: |
WashU-HHMI Mouse EST Project |
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Publication |
First Author: |
GUDMAP Consortium |
Year: |
2004 |
Journal: |
www.gudmap.org |
Title: |
GUDMAP: the GenitoUrinary Development Molecular Anatomy Project |
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Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2014 |
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Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
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Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
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Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt |
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Publication |
First Author: |
Magdaleno S |
Year: |
2006 |
Journal: |
PLoS Biol |
Title: |
BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. |
Volume: |
4 |
Issue: |
4 |
Pages: |
e86 |
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Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
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Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
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Title: |
GemPharmatech Website. |
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Publication |
First Author: |
Cyagen Biosciences Inc. |
Year: |
2022 |
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Title: |
Cyagen Biosciences Website. |
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Publication |
First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
Year: |
2011 |
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Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
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Publication |
First Author: |
GOA curators |
Year: |
2016 |
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Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
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Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
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Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
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Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
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Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
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Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
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Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
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Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
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Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
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Title: |
Annotation inferences using phylogenetic trees |
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Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
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Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
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Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
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Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
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•
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•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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•
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•
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Allele |
Name: |
mesenchyme homeobox 2; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Recombinase |
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•
•
•
•
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Strain |
Attribute String: |
coisogenic, mutant strain, endonuclease-mediated mutation |
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•
•
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Publication |
First Author: |
Mohamed JY |
Year: |
2013 |
Journal: |
Am J Hum Genet |
Title: |
Mutations in MEOX1, encoding mesenchyme homeobox 1, cause Klippel-Feil anomaly. |
Volume: |
92 |
Issue: |
1 |
Pages: |
157-61 |
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•
•
•
•
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Publication |
First Author: |
Bayrakli F |
Year: |
2013 |
Journal: |
BMC Genet |
Title: |
Mutation in MEOX1 gene causes a recessive Klippel-Feil syndrome subtype. |
Volume: |
14 |
|
Pages: |
95 |
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•
•
•
•
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Protein Domain |
Type: |
Family |
Description: |
MEOX1 and MEOX2 are homeodomain transcription factors that have been shown to be partially functionally redundant during development. They regulate the cyclin dependent kinase inhibitors p21 and p16 in vascular endothelial cells []. Nevertheless, MEOX1 also plays important, non-redundant roles in maintaining sclerotome polarity and the formation of cranio-cervical joints []. Mutations in the MEOX1 gene cause Klippel-Feil syndrome 2, autosomal recessive (KFS2), a skeletal disorder characterised by congenital fusion of cervical vertebrae [, ]. |
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HT Experiment |
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Experiment Type: |
RNA-Seq |
Study Type: |
Baseline |
Source: |
GEO |
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Publication |
First Author: |
Jin JZ |
Year: |
2014 |
Journal: |
Int J Dev Biol |
Title: |
Regional divergence of palate medial edge epithelium along the anterior to posterior axis. |
Volume: |
58 |
Issue: |
9 |
Pages: |
713-7 |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
253
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Fragment?: |
false |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
303
 |
Fragment?: |
false |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
303
 |
Fragment?: |
false |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
159
 |
Fragment?: |
true |
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