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Search results 901 to 1000 out of 2287 for Mx1

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Type Details Score
Publication
First Author: Burgess MR
Year: 2014
Journal: Blood
Title: Preclinical efficacy of MEK inhibition in Nras-mutant AML.
Volume: 124
Issue: 26
Pages: 3947-55
Publication
First Author: Sabnis AJ
Year: 2009
Journal: PLoS Biol
Title: Oncogenic Kras initiates leukemia in hematopoietic stem cells.
Volume: 7
Issue: 3
Pages: e59
Publication
First Author: Hönes JM
Year: 2017
Journal: Sci Rep
Title: Enforced GFI1 expression impedes human and murine leukemic cell growth.
Volume: 7
Issue: 1
Pages: 15720
Publication
First Author: Quivoron C
Year: 2011
Journal: Cancer Cell
Title: TET2 inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis.
Volume: 20
Issue: 1
Pages: 25-38
Publication
First Author: Møller AMJ
Year: 2018
Journal: Sci Rep
Title: Septins are critical regulators of osteoclastic bone resorption.
Volume: 8
Issue: 1
Pages: 13016
Publication
First Author: Zhang J
Year: 2009
Journal: Blood
Title: Oncogenic Kras-induced leukemogeneis: hematopoietic stem cells as the initial target and lineage-specific progenitors as the potential targets for final leukemic transformation.
Volume: 113
Issue: 6
Pages: 1304-14
Publication
First Author: Velasco-Hernandez T
Year: 2014
Journal: Blood
Title: HIF-1α can act as a tumor suppressor gene in murine acute myeloid leukemia.
Volume: 124
Issue: 24
Pages: 3597-607
Publication
First Author: Buxadé M
Year: 2018
Journal: J Exp Med
Title: Macrophage-specific MHCII expression is regulated by a remote Ciita enhancer controlled by NFAT5.
Volume: 215
Issue: 11
Pages: 2901-2918
Publication  
First Author: Edrees MAH
Year: 2019
Journal: Mol Immunol
Title: Ubc9 deficiency selectively impairs the functionality of common lymphoid progenitors (CLPs) during bone marrow hematopoiesis.
Volume: 114
Pages: 314-322
Publication
First Author: Volarevic S
Year: 2000
Journal: Science
Title: Proliferation, but not growth, blocked by conditional deletion of 40S ribosomal protein S6.
Volume: 288
Issue: 5473
Pages: 2045-7
Publication  
First Author: Coppo M
Year: 2016
Journal: Nat Commun
Title: The transcriptional coregulator GRIP1 controls macrophage polarization and metabolic homeostasis.
Volume: 7
Pages: 12254
Publication
First Author: Yuan X
Year: 2015
Journal: Cell Death Differ
Title: Regulators of G protein signaling 12 promotes osteoclastogenesis in bone remodeling and pathological bone loss.
Volume: 22
Issue: 12
Pages: 2046-57
Publication
First Author: Akada H
Year: 2014
Journal: Leukemia
Title: Loss of wild-type Jak2 allele enhances myeloid cell expansion and accelerates myelofibrosis in Jak2V617F knock-in mice.
Volume: 28
Issue: 8
Pages: 1627-35
Publication
First Author: Chan IT
Year: 2004
Journal: J Clin Invest
Title: Conditional expression of oncogenic K-ras from its endogenous promoter induces a myeloproliferative disease.
Volume: 113
Issue: 4
Pages: 528-38
Publication
First Author: Chan WI
Year: 2011
Journal: Mol Cell Biol
Title: The transcriptional coactivator Cbp regulates self-renewal and differentiation in adult hematopoietic stem cells.
Volume: 31
Issue: 24
Pages: 5046-60
Publication
First Author: Suzuki S
Year: 2020
Journal: Am J Physiol Lung Cell Mol Physiol
Title: ADAM17 protects against elastase-induced emphysema by suppressing CD62L+ leukocyte infiltration in mice.
Volume: 318
Issue: 6
Pages: L1172-L1182
Publication
First Author: Sportoletti P
Year: 2013
Journal: Blood
Title: The human NPM1 mutation A perturbs megakaryopoiesis in a conditional mouse model.
Volume: 121
Issue: 17
Pages: 3447-58
Publication
First Author: Kawagoe H
Year: 2005
Journal: Blood
Title: MN1-TEL myeloid oncoprotein expressed in multipotent progenitors perturbs both myeloid and lymphoid growth and causes T-lymphoid tumors in mice.
Volume: 106
Issue: 13
Pages: 4278-86
Publication  
First Author: Bombaci G
Year: 2022
Journal: Life Sci Alliance
Title: LRR-protein RNH1 dampens the inflammasome activation and is associated with COVID-19 severity.
Volume: 5
Issue: 6
Publication  
First Author: Stremmel C
Year: 2018
Journal: J Immunol Methods
Title: Inducible disruption of the c-myb gene allows allogeneic bone marrow transplantation without irradiation.
Volume: 457
Pages: 66-72
Publication
First Author: Cutts BA
Year: 2009
Journal: Blood
Title: Nf1 deficiency cooperates with oncogenic K-RAS to induce acute myeloid leukemia in mice.
Volume: 114
Issue: 17
Pages: 3629-32
Publication
First Author: Chinenov Y
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Role of transcriptional coregulator GRIP1 in the anti-inflammatory actions of glucocorticoids.
Volume: 109
Issue: 29
Pages: 11776-81
Publication
First Author: Wahlstrom AM
Year: 2007
Journal: Blood
Title: Rce1 deficiency accelerates the development of K-RAS-induced myeloproliferative disease.
Volume: 109
Issue: 2
Pages: 763-8
Publication
First Author: Laurenti E
Year: 2008
Journal: Cell Stem Cell
Title: Hematopoietic stem cell function and survival depend on c-Myc and N-Myc activity.
Volume: 3
Issue: 6
Pages: 611-24
Publication
First Author: Kong G
Year: 2014
Journal: J Clin Invest
Title: Combined MEK and JAK inhibition abrogates murine myeloproliferative neoplasm.
Volume: 124
Issue: 6
Pages: 2762-73
Publication
First Author: Leuenroth SJ
Year: 2010
Journal: Nephrol Dial Transplant
Title: Triptolide reduces cyst formation in a neonatal to adult transition Pkd1 model of ADPKD.
Volume: 25
Issue: 7
Pages: 2187-94
Publication
First Author: Du J
Year: 2012
Journal: Blood
Title: HIF-1α deletion partially rescues defects of hematopoietic stem cell quiescence caused by Cited2 deficiency.
Volume: 119
Issue: 12
Pages: 2789-98
Publication
First Author: Ricote M
Year: 2006
Journal: J Leukoc Biol
Title: Normal hematopoiesis after conditional targeting of RXRalpha in murine hematopoietic stem/progenitor cells.
Volume: 80
Issue: 4
Pages: 850-61
Publication  
First Author: Cao S
Year: 2021
Journal: Front Immunol
Title: The Transcription Factor FRA-1/AP-1 Controls Lipocalin-2 Expression and Inflammation in Sepsis Model.
Volume: 12
Pages: 701675
Publication
First Author: Brooks R
Year: 2010
Journal: J Immunol
Title: SHIP1 inhibition increases immunoregulatory capacity and triggers apoptosis of hematopoietic cancer cells.
Volume: 184
Issue: 7
Pages: 3582-9
Publication
First Author: Volpe G
Year: 2015
Journal: PLoS One
Title: Regulation of the Flt3 Gene in Haematopoietic Stem and Early Progenitor Cells.
Volume: 10
Issue: 9
Pages: e0138257
Publication
First Author: Silva VRR
Year: 2022
Journal: FASEB J
Title: Somatic ablation of IKKβ in liver and leukocytes is not tolerated in obese mice but hepatic IKKβ deletion improves fatty liver and insulin sensitivity.
Volume: 36
Issue: 9
Pages: e22512
Publication
First Author: Ng CE
Year: 2014
Journal: Leukemia
Title: KRas(G12D)-evoked leukemogenesis does not require β-catenin.
Volume: 28
Issue: 3
Pages: 698-702
Publication
First Author: Behrens A
Year: 2002
Journal: EMBO J
Title: Impaired postnatal hepatocyte proliferation and liver regeneration in mice lacking c-jun in the liver.
Volume: 21
Issue: 7
Pages: 1782-90
Publication
First Author: Sun S
Year: 2020
Journal: Leukemia
Title: Chromatin remodeler Znhit1 preserves hematopoietic stem cell quiescence by determining the accessibility of distal enhancers.
Volume: 34
Issue: 12
Pages: 3348-3358
Publication
First Author: Li X
Year: 2014
Journal: Stem Cells
Title: Stress hematopoiesis is regulated by the Krüppel-like transcription factor ZBP-89.
Volume: 32
Issue: 3
Pages: 791-801
Publication
First Author: Matsuura S
Year: 2012
Journal: Blood
Title: Expression of the runt homology domain of RUNX1 disrupts homeostasis of hematopoietic stem cells and induces progression to myelodysplastic syndrome.
Volume: 120
Issue: 19
Pages: 4028-37
Publication
First Author: Wang J
Year: 2013
Journal: Blood
Title: Nras(G12D/+) promotes leukemogenesis by aberrantly regulating hematopoietic stem cell functions.
Volume: 121
Issue: 26
Pages: 5203-7
Publication  
First Author: Rao TN
Year: 2018
Journal: EMBO J
Title: Attenuation of PKCδ enhances metabolic activity and promotes expansion of blood progenitors.
Volume: 37
Issue: 24
Publication
First Author: Beier F
Year: 2012
Journal: Blood
Title: Conditional TRF1 knockout in the hematopoietic compartment leads to bone marrow failure and recapitulates clinical features of dyskeratosis congenita.
Volume: 120
Issue: 15
Pages: 2990-3000
Publication  
First Author: Spinner CA
Year: 2015
Journal: Sci Rep
Title: Substrates of the ASB2α E3 ubiquitin ligase in dendritic cells.
Volume: 5
Pages: 16269
Publication
First Author: Jutzi JS
Year: 2023
Journal: Leukemia
Title: CALR-mutated cells are vulnerable to combined inhibition of the proteasome and the endoplasmic reticulum stress response.
Volume: 37
Issue: 2
Pages: 359-369
Publication
First Author: Wells CM
Year: 2004
Journal: J Cell Sci
Title: Rac1-deficient macrophages exhibit defects in cell spreading and membrane ruffling but not migration.
Volume: 117
Issue: Pt 7
Pages: 1259-68
Publication
First Author: Vasanthakumar A
Year: 2016
Journal: Blood
Title: Brca1 deficiency causes bone marrow failure and spontaneous hematologic malignancies in mice.
Volume: 127
Issue: 3
Pages: 310-3
Publication
First Author: Nieswandt B
Year: 2007
Journal: J Exp Med
Title: Loss of talin1 in platelets abrogates integrin activation, platelet aggregation, and thrombus formation in vitro and in vivo.
Volume: 204
Issue: 13
Pages: 3113-8
Publication
First Author: Luo B
Year: 2011
Journal: PLoS One
Title: The endoplasmic reticulum chaperone protein GRP94 is required for maintaining hematopoietic stem cell interactions with the adult bone marrow niche.
Volume: 6
Issue: 5
Pages: e20364
Publication
First Author: Luo B
Year: 2013
Journal: Stem Cells Dev
Title: Deficiency of GRP94 in the hematopoietic system alters proliferation regulators in hematopoietic stem cells.
Volume: 22
Issue: 23
Pages: 3062-73
Publication
First Author: Vemula S
Year: 2010
Journal: Blood
Title: Essential role for focal adhesion kinase in regulating stress hematopoiesis.
Volume: 116
Issue: 20
Pages: 4103-15
Publication
First Author: Ni H
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Plasma fibronectin promotes thrombus growth and stability in injured arterioles.
Volume: 100
Issue: 5
Pages: 2415-9
Publication
First Author: Chen Z
Year: 2025
Journal: Cell
Title: YTHDF2 promotes ATP synthesis and immune evasion in B cell malignancies.
Volume: 188
Issue: 2
Pages: 331-351.e30
Publication
First Author: Baker SJ
Year: 2019
Journal: Oncotarget
Title: Rigosertib ameliorates the effects of oncogenic KRAS signaling in a murine model of myeloproliferative neoplasia.
Volume: 10
Issue: 20
Pages: 1932-1942
Publication
First Author: Ge J
Year: 2010
Journal: Biochem J
Title: SnoRNA microarray analysis reveals changes in H/ACA and C/D RNA levels caused by dyskerin ablation in mouse liver.
Volume: 429
Issue: 1
Pages: 33-41
Publication
First Author: Lee D
Year: 2011
Journal: Stem Cells
Title: The Er71 is an important regulator of hematopoietic stem cells in adult mice.
Volume: 29
Issue: 3
Pages: 539-48
Publication
First Author: Guo Y
Year: 2009
Journal: Blood
Title: c-Myc-mediated control of cell fate in megakaryocyte-erythrocyte progenitors.
Volume: 114
Issue: 10
Pages: 2097-106
Publication
First Author: Wang J
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Histone demethylase LSD1 regulates hematopoietic stem cells homeostasis and protects from death by endotoxic shock.
Volume: 115
Issue: 2
Pages: E244-E252
Publication
First Author: Dooher JE
Year: 2011
Journal: Mol Cancer Res
Title: C/EBPα, C/EBPα oncoproteins, or C/EBPβ preferentially bind NF-κB p50 compared with p65, focusing therapeutic targeting on the C/EBP:p50 interaction.
Volume: 9
Issue: 10
Pages: 1395-405
Publication
First Author: Deshpande AJ
Year: 2014
Journal: Cancer Cell
Title: AF10 regulates progressive H3K79 methylation and HOX gene expression in diverse AML subtypes.
Volume: 26
Issue: 6
Pages: 896-908
Publication
First Author: Wada T
Year: 2008
Journal: Cell Death Differ
Title: Antagonistic control of cell fates by JNK and p38-MAPK signaling.
Volume: 15
Issue: 1
Pages: 89-93
Publication
First Author: Baena E
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: c-Myc regulates cell size and ploidy but is not essential for postnatal proliferation in liver.
Volume: 102
Issue: 20
Pages: 7286-91
Publication  
First Author: Kan C
Year: 2024
Journal: JCI Insight
Title: Phase separation of SHP2E76K promotes malignant transformation of mesenchymal stem cells by activating mitochondrial complexes.
Volume: 9
Issue: 8
Publication
First Author: Yang ZF
Year: 2011
Journal: Blood
Title: GABP transcription factor is required for myeloid differentiation, in part, through its control of Gfi-1 expression.
Volume: 118
Issue: 8
Pages: 2243-53
Publication
First Author: Mistry PK
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Glucocerebrosidase 2 gene deletion rescues type 1 Gaucher disease.
Volume: 111
Issue: 13
Pages: 4934-9
Publication
First Author: Koumakis E
Year: 2019
Journal: Sci Rep
Title: Novel function of PiT1/SLC20A1 in LPS-related inflammation and wound healing.
Volume: 9
Issue: 1
Pages: 1808
Publication
First Author: Dutta A
Year: 2017
Journal: Blood
Title: Hmga2 promotes the development of myelofibrosis in Jak2V617F knockin mice by enhancing TGF-β1 and Cxcl12 pathways.
Volume: 130
Issue: 7
Pages: 920-932
Publication
First Author: Hu P
Year: 2012
Journal: J Biol Chem
Title: p38α protein negatively regulates T helper type 2 responses by orchestrating multiple T cell receptor-associated signals.
Volume: 287
Issue: 40
Pages: 33215-26
Publication
First Author: Leung CG
Year: 2007
Journal: J Exp Med
Title: Requirements for survivin in terminal differentiation of erythroid cells and maintenance of hematopoietic stem and progenitor cells.
Volume: 204
Issue: 7
Pages: 1603-11
Publication
First Author: Chen H
Year: 2017
Journal: J Neurosci
Title: An Agonist of the Protective Factor SIRT1 Improves Functional Recovery and Promotes Neuronal Survival by Attenuating Inflammation after Spinal Cord Injury.
Volume: 37
Issue: 11
Pages: 2916-2930
Publication
First Author: Lyubynska N
Year: 2011
Journal: Sci Transl Med
Title: A MEK inhibitor abrogates myeloproliferative disease in Kras mutant mice.
Volume: 3
Issue: 76
Pages: 76ra27
Publication
First Author: Akbar H
Year: 2011
Journal: PLoS One
Title: Gene targeting implicates Cdc42 GTPase in GPVI and non-GPVI mediated platelet filopodia formation, secretion and aggregation.
Volume: 6
Issue: 7
Pages: e22117
Publication
First Author: Growney JD
Year: 2005
Journal: Blood
Title: Loss of Runx1 perturbs adult hematopoiesis and is associated with a myeloproliferative phenotype.
Volume: 106
Issue: 2
Pages: 494-504
Publication
First Author: Ochi Y
Year: 2020
Journal: Cancer Discov
Title: Combined Cohesin-RUNX1 Deficiency Synergistically Perturbs Chromatin Looping and Causes Myelodysplastic Syndromes.
Volume: 10
Issue: 6
Pages: 836-853
Publication
First Author: Zhang J
Year: 2015
Journal: PLoS One
Title: Loss of IKKβ but Not NF-κB p65 Skews Differentiation towards Myeloid over Erythroid Commitment and Increases Myeloid Progenitor Self-Renewal and Functional Long-Term Hematopoietic Stem Cells.
Volume: 10
Issue: 6
Pages: e0130441
Publication
First Author: Piao X
Year: 2012
Journal: Sci Signal
Title: c-FLIP maintains tissue homeostasis by preventing apoptosis and programmed necrosis.
Volume: 5
Issue: 255
Pages: ra93
Publication
First Author: Nishimichi N
Year: 2011
Journal: J Biol Chem
Title: Osteopontin undergoes polymerization in vivo and gains chemotactic activity for neutrophils mediated by integrin alpha9beta1.
Volume: 286
Issue: 13
Pages: 11170-8
Publication
First Author: Kawelke N
Year: 2011
Journal: PLoS One
Title: Fibronectin protects from excessive liver fibrosis by modulating the availability of and responsiveness of stellate cells to active TGF-β.
Volume: 6
Issue: 11
Pages: e28181
Publication  
First Author: Bopp A
Year: 2013
Journal: Cell Death Dis
Title: Rac1 modulates acute and subacute genotoxin-induced hepatic stress responses, fibrosis and liver aging.
Volume: 4
Pages: e558
Publication
First Author: Akutagawa J
Year: 2016
Journal: Leukemia
Title: Targeting the PI3K/Akt pathway in murine MDS/MPN driven by hyperactive Ras.
Volume: 30
Issue: 6
Pages: 1335-43
Publication
First Author: Yeligar SM
Year: 2010
Journal: J Biol Chem
Title: Ethanol-induced HO-1 and NQO1 are differentially regulated by HIF-1alpha and Nrf2 to attenuate inflammatory cytokine expression.
Volume: 285
Issue: 46
Pages: 35359-73
Publication
First Author: Malik G
Year: 2010
Journal: Cancer Res
Title: Plasma fibronectin promotes lung metastasis by contributions to fibrin clots and tumor cell invasion.
Volume: 70
Issue: 11
Pages: 4327-34
Publication
First Author: Sakai T
Year: 2001
Journal: Nat Med
Title: Plasma fibronectin supports neuronal survival and reduces brain injury following transient focal cerebral ischemia but is not essential for skin-wound healing and hemostasis.
Volume: 7
Issue: 3
Pages: 324-30
Publication
First Author: Hao Z
Year: 2001
Journal: J Exp Med
Title: Homeostasis of peripheral B cells in the absence of B cell influx from the bone marrow.
Volume: 194
Issue: 8
Pages: 1151-64
Publication  
First Author: Krasteva V
Year: 2017
Journal: Exp Hematol
Title: The BAF45a/PHF10 subunit of SWI/SNF-like chromatin remodeling complexes is essential for hematopoietic stem cell maintenance.
Volume: 48
Pages: 58-71.e15
Publication
First Author: Katzerke C
Year: 2013
Journal: Blood
Title: Transcription factor C/EBPα-induced microRNA-30c inactivates Notch1 during granulopoiesis and is downregulated in acute myeloid leukemia.
Volume: 122
Issue: 14
Pages: 2433-42
Publication    
First Author: Domingues AF
Year: 2020
Journal: Elife
Title: Loss of Kat2a enhances transcriptional noise and depletes acute myeloid leukemia stem-like cells.
Volume: 9
Publication  
First Author: Kim H
Year: 2015
Journal: Sci Rep
Title: A novel crosstalk between TLR4- and NOD2-mediated signaling in the regulation of intestinal inflammation.
Volume: 5
Pages: 12018
Publication
First Author: Rius J
Year: 2008
Journal: Nature
Title: NF-kappaB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1alpha.
Volume: 453
Issue: 7196
Pages: 807-11
Publication
First Author: Diaz-Flores E
Year: 2013
Journal: Sci Signal
Title: PLC-γ and PI3K link cytokines to ERK activation in hematopoietic cells with normal and oncogenic Kras.
Volume: 6
Issue: 304
Pages: ra105
Publication
First Author: Hashimoto A
Year: 2000
Journal: J Immunol
Title: Cutting edge: essential role of phospholipase C-gamma 2 in B cell development and function.
Volume: 165
Issue: 4
Pages: 1738-42
Publication
First Author: Lieu YK
Year: 2012
Journal: Cell Cycle
Title: Impaired adult myeloid progenitor CMP and GMP cell function in conditional c-myb-knockout mice.
Volume: 11
Issue: 18
Pages: 3504-12
Publication
First Author: Fenouille N
Year: 2017
Journal: Nat Med
Title: The creatine kinase pathway is a metabolic vulnerability in EVI1-positive acute myeloid leukemia.
Volume: 23
Issue: 3
Pages: 301-313
Publication
First Author: Chen F
Year: 2018
Journal: Biochem Biophys Res Commun
Title: Protein disulfide isomerase enhances tissue factor-dependent thrombin generation.
Volume: 501
Issue: 1
Pages: 172-177
Publication
First Author: Müller TA
Year: 2016
Journal: Leukemia
Title: Lineage-specific STAT5 target gene activation in hematopoietic progenitor cells predicts the FLT3(+)-mediated leukemic phenotype.
Volume: 30
Issue: 8
Pages: 1725-33
Publication
First Author: Wei J
Year: 2018
Journal: Nat Commun
Title: ER-associated ubiquitin ligase HRD1 programs liver metabolism by targeting multiple metabolic enzymes.
Volume: 9
Issue: 1
Pages: 3659
Publication
First Author: Keel SB
Year: 2012
Journal: Exp Hematol
Title: Establishing Rps6 hemizygous mice as a model for studying how ribosomal protein haploinsufficiency impairs erythropoiesis.
Volume: 40
Issue: 4
Pages: 290-4
Publication
First Author: Takeuchi Y
Year: 2002
Journal: J Biol Chem
Title: Interleukin-11 as a stimulatory factor for bone formation prevents bone loss with advancing age in mice.
Volume: 277
Issue: 50
Pages: 49011-8
Genotype
Symbol: Meox1/Meox1 Meox2/Meox2
Background: involves: 129P2/OlaHsd * C3H/HeJ * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Meox1/Meox1
Background: involves: C3H/HeJ * C57BL/6
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Kras/Kras<+> Tg(Mx1-cre)1Cgn/?
Background: involves: 129S4/SvJae * BALB/c * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Dll1/Dll1 Tg(KRT5-cre)1Tak/? Tg(Mx1-cre)1Cgn/?
Background: involves: 129 * C3H * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Csk/Csk Tg(Mx1-cre)1Cgn/?
Background: involves: 129P2/OlaHsd * C57BL/6 * CB20 * CBA
Zygosity: cn
Has Mutant Allele: true