| Type |
Details |
Score |
| Publication |
| First Author: |
Casellas J |
| Year: |
2010 |
| Journal: |
J Hered |
| Title: |
Segregation analysis of a sex ratio distortion locus in congenic mice. |
| Volume: |
101 |
| Issue: |
3 |
| Pages: |
351-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bradford GE |
| Year: |
1984 |
| Journal: |
Genet Res |
| Title: |
Evidence for a major gene for rapid postweaning growth in mice. |
| Volume: |
44 |
| Issue: |
3 |
| Pages: |
293-308 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Calvert CC |
| Year: |
1986 |
| Journal: |
J Anim Sci |
| Title: |
Efficiency of growth in mice with a major gene for rapid postweaning gain. |
| Volume: |
62 |
| Issue: |
1 |
| Pages: |
77-85 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Reiser K |
| Year: |
1996 |
| Journal: |
Am J Physiol |
| Title: |
Effects of elevated circulating IGF-1 on the extracellular matrix in "high-growth" C57BL/6J mice. |
| Volume: |
271 |
| Issue: |
3 Pt 2 |
| Pages: |
R696-703 |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Mohg1/Mohg1 Socs2/Socs2 |
| Background: |
involves: C57BL/6J * CAST/EiJ |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Mohg3/Mohg3 Socs2/Socs2 |
| Background: |
involves: C57BL/6J * CAST/EiJ |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Mohg3/Mohg3 Socs2/Socs2 |
| Background: |
involves: C57BL/6J * CAST/EiJ |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Socs2/Socs2 |
| Background: |
involves: AKR/J * C3H/HeJ * C57BL/6J * DBA/2J |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Pearson JS |
| Year: |
2017 |
| Journal: |
Nat Microbiol |
| Title: |
EspL is a bacterial cysteine protease effector that cleaves RHIM proteins to block necroptosis and inflammation. |
| Volume: |
2 |
|
| Pages: |
16258 |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Domain |
| Description: |
This domain is present in the N-terminal region of the ShET2 enterotoxin produced by Shigella flexneri () and Escherichia coli (). This protein was found to confer toxigenicity in Ussing chamber assays, and the N-terminal region was found to be important for its enterotoxic effect. The N-terminal domain is a cysteine-type peptidase with a Cys/His/Asp catalytic triad that cleaves within the receptor-interacting protein homotypic interaction motifs found within host adaptor proteins such as receptor-interacting serine/threonine protein kinases RIPK1 and RIPK3, TIR-domain-containing adapter-inducing interferon beta and Z-DNA-binding protein 1, inactivating them and thus inhibiting necroptosis and inflammatory signalling []. The toxin is injected into the host cell by the type III secretion system [].Most proteins containing this domain are annotated as putative enterotoxins, but one member () is a regulator of acetyl CoA synthetase, and another two members (and ) are annotated as ankyrin-like regulatory proteins and contain Ank repeats (). |
|
•
•
•
•
•
|
| HT Experiment |
|
| Experiment Type: |
RNA-Seq |
| Study Type: |
WT vs. Mutant |
| Source: |
GEO |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
congenic, mutant strain, spontaneous mutation, deletion |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
congenic, mutant strain, spontaneous mutation, deletion, QTL |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
congenic, mutant strain, deletion, spontaneous mutation |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wu R |
| Year: |
2005 |
| Journal: |
Genetics |
| Title: |
Functional mapping of quantitative trait loci that interact with the hg mutation to regulate growth trajectories in mice. |
| Volume: |
171 |
| Issue: |
1 |
| Pages: |
239-49 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Farber CR |
| Year: |
2008 |
| Journal: |
BMC Genet |
| Title: |
Overexpression of Scg5 increases enzymatic activity of PCSK2 and is inversely correlated with body weight in congenic mice. |
| Volume: |
9 |
|
| Pages: |
34 |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Mohg1/Mohg1 Socs2/Socs2 |
| Background: |
involves: C57BL/6J * CAST/EiJ |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Mohg2/Mohg2 Socs2/Socs2 |
| Background: |
involves: C57BL/6J * CAST/EiJ |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Stennicke HR |
| Year: |
2000 |
| Journal: |
Biochem J |
| Title: |
Internally quenched fluorescent peptide substrates disclose the subsite preferences of human caspases 1, 3, 6, 7 and 8. |
| Volume: |
350 Pt 2 |
|
| Pages: |
563-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nogusa S |
| Year: |
2016 |
| Journal: |
Cell Host Microbe |
| Title: |
RIPK3 Activates Parallel Pathways of MLKL-Driven Necroptosis and FADD-Mediated Apoptosis to Protect against Influenza A Virus. |
| Volume: |
20 |
| Issue: |
1 |
| Pages: |
13-24 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Thapa RJ |
| Year: |
2016 |
| Journal: |
Cell Host Microbe |
| Title: |
DAI Senses Influenza A Virus Genomic RNA and Activates RIPK3-Dependent Cell Death. |
| Volume: |
20 |
| Issue: |
5 |
| Pages: |
674-681 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Rodrigue-Gervais IG |
| Year: |
2014 |
| Journal: |
Cell Host Microbe |
| Title: |
Cellular inhibitor of apoptosis protein cIAP2 protects against pulmonary tissue necrosis during influenza virus infection to promote host survival. |
| Volume: |
15 |
| Issue: |
1 |
| Pages: |
23-35 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Morioka S |
| Year: |
2014 |
| Journal: |
J Cell Biol |
| Title: |
TAK1 kinase switches cell fate from apoptosis to necrosis following TNF stimulation. |
| Volume: |
204 |
| Issue: |
4 |
| Pages: |
607-23 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ito-Kureha T |
| Year: |
2022 |
| Journal: |
Nat Immunol |
| Title: |
The function of Wtap in N6-adenosine methylation of mRNAs controls T cell receptor signaling and survival of T cells. |
| Volume: |
23 |
| Issue: |
8 |
| Pages: |
1208-1221 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yow SJ |
| Year: |
2024 |
| Journal: |
Cell Death Dis |
| Title: |
Differential signalling requirements for RIPK1-dependent pyroptosis in neutrophils and macrophages. |
| Volume: |
15 |
| Issue: |
7 |
| Pages: |
479 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wu YH |
| Year: |
2022 |
| Journal: |
Sci Adv |
| Title: |
Caspase-8 inactivation drives autophagy-dependent inflammasome activation in myeloid cells. |
| Volume: |
8 |
| Issue: |
45 |
| Pages: |
eabn9912 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Naito MG |
| Year: |
2020 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Sequential activation of necroptosis and apoptosis cooperates to mediate vascular and neural pathology in stroke. |
| Volume: |
117 |
| Issue: |
9 |
| Pages: |
4959-4970 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kang TB |
| Year: |
2013 |
| Journal: |
Immunity |
| Title: |
Caspase-8 blocks kinase RIPK3-mediated activation of the NLRP3 inflammasome. |
| Volume: |
38 |
| Issue: |
1 |
| Pages: |
27-40 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kattah MG |
| Year: |
2018 |
| Journal: |
J Exp Med |
| Title: |
A20 and ABIN-1 synergistically preserve intestinal epithelial cell survival. |
| Volume: |
215 |
| Issue: |
7 |
| Pages: |
1839-1852 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Pajuelo D |
| Year: |
2018 |
| Journal: |
Cell Rep |
| Title: |
NAD+ Depletion Triggers Macrophage Necroptosis, a Cell Death Pathway Exploited by Mycobacterium tuberculosis. |
| Volume: |
24 |
| Issue: |
2 |
| Pages: |
429-440 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kitur K |
| Year: |
2016 |
| Journal: |
Cell Rep |
| Title: |
Necroptosis Promotes Staphylococcus aureus Clearance by Inhibiting Excessive Inflammatory Signaling. |
| Volume: |
16 |
| Issue: |
8 |
| Pages: |
2219-2230 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Alvarez-Diaz S |
| Year: |
2016 |
| Journal: |
Immunity |
| Title: |
The Pseudokinase MLKL and the Kinase RIPK3 Have Distinct Roles in Autoimmune Disease Caused by Loss of Death-Receptor-Induced Apoptosis. |
| Volume: |
45 |
| Issue: |
3 |
| Pages: |
513-526 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Duprez L |
| Year: |
2011 |
| Journal: |
Immunity |
| Title: |
RIP kinase-dependent necrosis drives lethal systemic inflammatory response syndrome. |
| Volume: |
35 |
| Issue: |
6 |
| Pages: |
908-18 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang JJ |
| Year: |
2020 |
| Journal: |
Nat Commun |
| Title: |
Disruption of auto-inhibition underlies conformational signaling of ASIC1a to induce neuronal necroptosis. |
| Volume: |
11 |
| Issue: |
1 |
| Pages: |
475 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Matsuzawa-Ishimoto Y |
| Year: |
2017 |
| Journal: |
J Exp Med |
| Title: |
Autophagy protein ATG16L1 prevents necroptosis in the intestinal epithelium. |
| Volume: |
214 |
| Issue: |
12 |
| Pages: |
3687-3705 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lee SB |
| Year: |
2019 |
| Journal: |
Nat Cell Biol |
| Title: |
The AMPK-Parkin axis negatively regulates necroptosis and tumorigenesis by inhibiting the necrosome. |
| Volume: |
21 |
| Issue: |
8 |
| Pages: |
940-951 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ofengeim D |
| Year: |
2015 |
| Journal: |
Cell Rep |
| Title: |
Activation of necroptosis in multiple sclerosis. |
| Volume: |
10 |
| Issue: |
11 |
| Pages: |
1836-49 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Dagenais M |
| Year: |
2016 |
| Journal: |
Mucosal Immunol |
| Title: |
A critical role for cellular inhibitor of protein 2 (cIAP2) in colitis-associated colorectal cancer and intestinal homeostasis mediated by the inflammasome and survival pathways. |
| Volume: |
9 |
| Issue: |
1 |
| Pages: |
146-58 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Caccamo A |
| Year: |
2017 |
| Journal: |
Nat Neurosci |
| Title: |
Necroptosis activation in Alzheimer's disease. |
| Volume: |
20 |
| Issue: |
9 |
| Pages: |
1236-1246 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
He S |
| Year: |
2009 |
| Journal: |
Cell |
| Title: |
Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha. |
| Volume: |
137 |
| Issue: |
6 |
| Pages: |
1100-11 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Li D |
| Year: |
2020 |
| Journal: |
Elife |
| Title: |
Casein kinase 1G2 suppresses necroptosis-promoted testis aging by inhibiting receptor-interacting kinase 3. |
| Volume: |
9 |
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tanzer MC |
| Year: |
2017 |
| Journal: |
Cell Death Differ |
| Title: |
Combination of IAP antagonist and IFNγ activates novel caspase-10- and RIPK1-dependent cell death pathways. |
| Volume: |
24 |
| Issue: |
3 |
| Pages: |
481-491 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lim J |
| Year: |
2019 |
| Journal: |
Elife |
| Title: |
Autophagy regulates inflammatory programmed cell death via turnover of RHIM-domain proteins. |
| Volume: |
8 |
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang H |
| Year: |
2020 |
| Journal: |
Cell Rep |
| Title: |
Crucial Roles of the RIP Homotypic Interaction Motifs of RIPK3 in RIPK1-Dependent Cell Death and Lymphoproliferative Disease. |
| Volume: |
31 |
| Issue: |
7 |
| Pages: |
107650 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kumari S |
| Year: |
2021 |
| Journal: |
Life Sci Alliance |
| Title: |
NF-κB inhibition in keratinocytes causes RIPK1-mediated necroptosis and skin inflammation. |
| Volume: |
4 |
| Issue: |
6 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zou Y |
| Year: |
2022 |
| Journal: |
Cell Death Dis |
| Title: |
Deficiency of PPP6C protects TNF-induced necroptosis through activation of TAK1. |
| Volume: |
13 |
| Issue: |
7 |
| Pages: |
618 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Li M |
| Year: |
2022 |
| Journal: |
Dev Cell |
| Title: |
Gasdermin D maintains bone mass by rewiring the endo-lysosomal pathway of osteoclastic bone resorption. |
| Volume: |
57 |
| Issue: |
20 |
| Pages: |
2365-2380.e8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Farber CR |
| Year: |
2006 |
| Journal: |
BMC Genomics |
| Title: |
Genome-wide isolation of growth and obesity QTL using mouse speed congenic strains. |
| Volume: |
7 |
|
| Pages: |
102 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Farber CR |
| Year: |
2007 |
| Journal: |
Genetics |
| Title: |
Fine mapping reveals sex bias in quantitative trait loci affecting growth, skeletal size and obesity-related traits on mouse chromosomes 2 and 11. |
| Volume: |
175 |
| Issue: |
1 |
| Pages: |
349-60 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lee S |
| Year: |
2021 |
| Journal: |
Nature |
| Title: |
AIM2 forms a complex with pyrin and ZBP1 to drive PANoptosis and host defence. |
| Volume: |
597 |
| Issue: |
7876 |
| Pages: |
415-419 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Vince JE |
| Year: |
2009 |
| Journal: |
J Biol Chem |
| Title: |
TRAF2 must bind to cellular inhibitors of apoptosis for tumor necrosis factor (tnf) to efficiently activate nf-{kappa}b and to prevent tnf-induced apoptosis. |
| Volume: |
284 |
| Issue: |
51 |
| Pages: |
35906-15 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ang RL |
| Year: |
2021 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Immune dysregulation in SHARPIN-deficient mice is dependent on CYLD-mediated cell death. |
| Volume: |
118 |
| Issue: |
50 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Orvedahl A |
| Year: |
2019 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Autophagy genes in myeloid cells counteract IFNγ-induced TNF-mediated cell death and fatal TNF-induced shock. |
| Volume: |
116 |
| Issue: |
33 |
| Pages: |
16497-16506 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Anderton H |
| Year: |
2017 |
| Journal: |
J Invest Dermatol |
| Title: |
Inhibitor of Apoptosis Proteins (IAPs) Limit RIPK1-Mediated Skin Inflammation. |
| Volume: |
137 |
| Issue: |
11 |
| Pages: |
2371-2379 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wei J |
| Year: |
2023 |
| Journal: |
Signal Transduct Target Ther |
| Title: |
Elevated peripheral levels of receptor-interacting protein kinase 1 (RIPK1) and IL-8 as biomarkers of human amyotrophic lateral sclerosis. |
| Volume: |
8 |
| Issue: |
1 |
| Pages: |
451 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang T |
| Year: |
2020 |
| Journal: |
Cell Death Differ |
| Title: |
Necroptosis is dispensable for motor neuron degeneration in a mouse model of ALS. |
| Volume: |
27 |
| Issue: |
5 |
| Pages: |
1728-1739 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Dermentzaki G |
| Year: |
2019 |
| Journal: |
eNeuro |
| Title: |
Deletion of Ripk3 Prevents Motor Neuron Death In Vitro but not In Vivo. |
| Volume: |
6 |
| Issue: |
1 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lu C |
| Year: |
2022 |
| Journal: |
Invest Ophthalmol Vis Sci |
| Title: |
Rapamycin Inhibits Light-Induced Necrosome Activation Occurring in Wild-Type, but not RPE65-Null, Mouse Retina. |
| Volume: |
63 |
| Issue: |
13 |
| Pages: |
19 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Downey J |
| Year: |
2017 |
| Journal: |
PLoS Pathog |
| Title: |
RIPK3 interacts with MAVS to regulate type I IFN-mediated immunity to Influenza A virus infection. |
| Volume: |
13 |
| Issue: |
4 |
| Pages: |
e1006326 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Linkermann A |
| Year: |
2013 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Two independent pathways of regulated necrosis mediate ischemia-reperfusion injury. |
| Volume: |
110 |
| Issue: |
29 |
| Pages: |
12024-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Petersen SL |
| Year: |
2015 |
| Journal: |
Cell Death Differ |
| Title: |
TRAF2 is a biologically important necroptosis suppressor. |
| Volume: |
22 |
| Issue: |
11 |
| Pages: |
1846-57 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Schreiber A |
| Year: |
2017 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Necroptosis controls NET generation and mediates complement activation, endothelial damage, and autoimmune vasculitis. |
| Volume: |
114 |
| Issue: |
45 |
| Pages: |
E9618-E9625 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Seo J |
| Year: |
2016 |
| Journal: |
Nat Cell Biol |
| Title: |
CHIP controls necroptosis through ubiquitylation- and lysosome-dependent degradation of RIPK3. |
| Volume: |
18 |
| Issue: |
3 |
| Pages: |
291-302 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Pavlosky A |
| Year: |
2014 |
| Journal: |
Am J Transplant |
| Title: |
RIPK3-mediated necroptosis regulates cardiac allograft rejection. |
| Volume: |
14 |
| Issue: |
8 |
| Pages: |
1778-90 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jouan-Lanhouet S |
| Year: |
2012 |
| Journal: |
Cell Death Differ |
| Title: |
TRAIL induces necroptosis involving RIPK1/RIPK3-dependent PARP-1 activation. |
| Volume: |
19 |
| Issue: |
12 |
| Pages: |
2003-14 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Xu C |
| Year: |
2021 |
| Journal: |
Theranostics |
| Title: |
TNF-α-dependent neuronal necroptosis regulated in Alzheimer's disease by coordination of RIPK1-p62 complex with autophagic UVRAG. |
| Volume: |
11 |
| Issue: |
19 |
| Pages: |
9452-9469 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang X |
| Year: |
2018 |
| Journal: |
Front Physiol |
| Title: |
Mechanisms of Pancreatic Injury Induced by Basic Amino Acids Differ Between L-Arginine, L-Ornithine, and L-Histidine. |
| Volume: |
9 |
|
| Pages: |
1922 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Pawar M |
| Year: |
2017 |
| Journal: |
Cell Death Differ |
| Title: |
FAS apoptotic inhibitory molecule 2 is a stress-induced intrinsic neuroprotective factor in the retina. |
| Volume: |
24 |
| Issue: |
10 |
| Pages: |
1799-1810 |
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| First Author: |
Tonnus W |
| Year: |
2021 |
| Journal: |
Nat Commun |
| Title: |
Dysfunction of the key ferroptosis-surveilling systems hypersensitizes mice to tubular necrosis during acute kidney injury. |
| Volume: |
12 |
| Issue: |
1 |
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4402 |
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| First Author: |
Xu D |
| Year: |
2020 |
| Journal: |
Nature |
| Title: |
Modulating TRADD to restore cellular homeostasis and inhibit apoptosis. |
| Volume: |
587 |
| Issue: |
7832 |
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133-138 |
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•
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| First Author: |
Bynigeri RR |
| Year: |
2024 |
| Journal: |
BMC Biol |
| Title: |
The protein phosphatase PP6 promotes RIPK1-dependent PANoptosis. |
| Volume: |
22 |
| Issue: |
1 |
| Pages: |
122 |
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•
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| Publication |
| First Author: |
Hu YB |
| Year: |
2019 |
| Journal: |
Cell Death Dis |
| Title: |
miR-425 deficiency promotes necroptosis and dopaminergic neurodegeneration in Parkinson's disease. |
| Volume: |
10 |
| Issue: |
8 |
| Pages: |
589 |
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| First Author: |
Londoño D |
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2011 |
| Journal: |
J Immunol |
| Title: |
IL-10 Prevents apoptosis of brain endothelium during bacteremia. |
| Volume: |
186 |
| Issue: |
12 |
| Pages: |
7176-86 |
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| First Author: |
Zhang C |
| Year: |
2019 |
| Journal: |
Cell Death Dis |
| Title: |
Inhibition of HtrA2 alleviated dextran sulfate sodium (DSS)-induced colitis by preventing necroptosis of intestinal epithelial cells. |
| Volume: |
10 |
| Issue: |
5 |
| Pages: |
344 |
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| Publication |
| First Author: |
Jean-Charles PY |
| Year: |
2018 |
| Journal: |
Arterioscler Thromb Vasc Biol |
| Title: |
USP20 (Ubiquitin-Specific Protease 20) Inhibits TNF (Tumor Necrosis Factor)-Triggered Smooth Muscle Cell Inflammation and Attenuates Atherosclerosis. |
| Volume: |
38 |
| Issue: |
10 |
| Pages: |
2295-2305 |
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| First Author: |
Molnár T |
| Year: |
2021 |
| Journal: |
FEBS J |
| Title: |
Caspase-9 acts as a regulator of necroptotic cell death. |
| Volume: |
288 |
| Issue: |
22 |
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6476-6491 |
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| First Author: |
Lin S |
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2024 |
| Journal: |
Cancer Lett |
| Title: |
Exosomal lncCRLA is predictive for the evolvement and development of lung adenocarcinoma. |
| Volume: |
582 |
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216588 |
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Reed JC |
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2003 |
| Journal: |
Genome Res |
| Title: |
Comparative analysis of apoptosis and inflammation genes of mice and humans. |
| Volume: |
13 |
| Issue: |
6B |
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1376-88 |
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Corva PM |
| Year: |
2001 |
| Journal: |
Mamm Genome |
| Title: |
Quantitative trait loci affecting growth in high growth (hg) mice. |
| Volume: |
12 |
| Issue: |
4 |
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284-90 |
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Lin Q |
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2006 |
| Journal: |
Nucleic Acids Res |
| Title: |
Mutagenesis of diploid mammalian genes by gene entrapment. |
| Volume: |
34 |
| Issue: |
20 |
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e139 |
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| First Author: |
Zoubek ME |
| Year: |
2019 |
| Journal: |
J Pathol |
| Title: |
Protective role of c-Jun N-terminal kinase-2 (JNK2) in ibuprofen-induced acute liver injury. |
| Volume: |
247 |
| Issue: |
1 |
| Pages: |
110-122 |
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| First Author: |
Cao LL |
| Year: |
2021 |
| Journal: |
J Neuroinflammation |
| Title: |
Downregulating expression of OPTN elevates neuroinflammation via AIM2 inflammasome- and RIPK1-activating mechanisms in APP/PS1 transgenic mice. |
| Volume: |
18 |
| Issue: |
1 |
| Pages: |
281 |
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| First Author: |
Canet-Pons J |
| Year: |
2021 |
| Journal: |
Neurobiol Dis |
| Title: |
Atxn2-CAG100-KnockIn mouse spinal cord shows progressive TDP43 pathology associated with cholesterol biosynthesis suppression. |
| Volume: |
152 |
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105289 |
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| First Author: |
Song YF |
| Year: |
2020 |
| Journal: |
Free Radic Biol Med |
| Title: |
The circular RNA TLK1 exacerbates myocardial ischemia/reperfusion injury via targeting miR-214/RIPK1 through TNF signaling pathway. |
| Volume: |
155 |
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69-80 |
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| First Author: |
Arrázola MS |
| Year: |
2019 |
| Journal: |
J Neurosci |
| Title: |
Axonal Degeneration Is Mediated by Necroptosis Activation. |
| Volume: |
39 |
| Issue: |
20 |
| Pages: |
3832-3844 |
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•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
480
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
480
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
480
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
500
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
NIH Mouse Knockout Inventory |
| Year: |
2004 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Information obtained from the NIH Mouse Knockout Inventory |
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•
•
•
•
•
|
| Publication |
| First Author: |
Tang F |
| Year: |
2011 |
| Journal: |
PLoS One |
| Title: |
Deterministic and stochastic allele specific gene expression in single mouse blastomeres. |
| Volume: |
6 |
| Issue: |
6 |
| Pages: |
e21208 |
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•
•
•
•
•
|
| Publication |
| First Author: |
University of California, Davis |
| Year: |
2010 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Alleles produced for the KOMP project by the University of California, Davis |
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•
•
•
•
•
|
| Publication |
| First Author: |
Birgit Meldal and Sandra Orchard (1). (1) European Bioinformatics Institute (EBI), Hinxton, Cambridgeshire, United Kingdom |
| Year: |
2023 |
|
| Title: |
Manual transfer of experimentally-verified manual GO annotation data to homologous complexes by curator judgment of sequence, composition and function similarity |
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•
•
•
•
•
|
| Publication |
| First Author: |
Friedel RH |
| Year: |
2007 |
| Journal: |
Brief Funct Genomic Proteomic |
| Title: |
EUCOMM--the European conditional mouse mutagenesis program. |
| Volume: |
6 |
| Issue: |
3 |
| Pages: |
180-5 |
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•
•
•
•
|
| Publication |
| First Author: |
Hansen J |
| Year: |
2003 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. |
| Volume: |
100 |
| Issue: |
17 |
| Pages: |
9918-22 |
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•
•
•
|
| Publication |
| First Author: |
Stryke D |
| Year: |
2003 |
| Journal: |
Nucleic Acids Res |
| Title: |
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. |
| Volume: |
31 |
| Issue: |
1 |
| Pages: |
278-81 |
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•
•
•
•
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