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Search results 901 to 941 out of 941 for Sfrp1

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Type Details Score
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication  
First Author: Lopez-Rios J
Year: 2008
Journal: Neural Dev
Title: The Netrin-related domain of Sfrp1 interacts with Wnt ligands and antagonizes their activity in the anterior neural plate.
Volume: 3
Pages: 19
Allele
Name: secreted frizzled-related protein 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Interaction Experiment
Description: Sfrp1 and Sfrp2 regulate anteroposterior axis elongation and somite segmentation during mouse embryogenesis.
Strain
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
Allele
Name: transgene insertion 1, Paul C Marker
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Strain
Attribute String: transgenic, coisogenic
Genotype
Symbol: Tg(Pbsn-SFRP1)1Pcma/?
Background: FVB/N-Tg(Pbsn-SFRP1)1Pcma
Zygosity: ot
Has Mutant Allele: true
HT Experiment
Series Id: GSE39224
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
Publication
First Author: Choi JH
Year: 2011
Journal: BMB Rep
Title: Downregulation of Foxe1 by HR suppresses Msx1 expression in the hair follicles of Hr(Hp) mice.
Volume: 44
Issue: 7
Pages: 478-83
Publication
First Author: Agostino M
Year: 2017
Journal: J Biol Chem
Title: Structure-based prediction of Wnt binding affinities for Frizzled-type cysteine-rich domains.
Volume: 292
Issue: 27
Pages: 11218-11229
Protein Domain
Type: Domain
Description: The cysteine-rich domain (CRD) is an essential part of the secreted frizzled-related protein 1 (SFRP1), which is an antagonist of the Wnt-Frizzled pathway and is involved in regulating many processes, such as vascular cell proliferation [], heart morphogenesis [], bone trabecular formation []and lung morphogenesis []. SFRP1 is expressed in many tissues and is involved in the regulation of Wnt signaling in osteoblasts, leading to enhanced trabecular bone formation in adults; it has also been shown to control the growth of retinal ganglion cell axons and the elongation of the antero-posterior axis [, ].In general, SFRPs antagonize the activation of Wnt signaling by binding to the CRD domains of frizzled (Fz) proteins, thereby preventing Wnt proteins from binding to these receptors. SFRPs are also known to have functions unrelated to Wnt, as enhancers of procollagen cleavage by the TLD proteinases []. SFRPs and Fz proteins both contain CRD domains, but SFRPs lack the seven-pass transmembrane domain which is an integral part of Fzs [, ].
Publication
First Author: Huang S
Year: 2020
Journal: Cell Rep
Title: Demyelination Regulates the Circadian Transcription Factor BMAL1 to Signal Adult Neural Stem Cells to Initiate Oligodendrogenesis.
Volume: 33
Issue: 7
Pages: 108394
Publication
First Author: Konkimalla A
Year: 2023
Journal: Cell Stem Cell
Title: Transitional cell states sculpt tissue topology during lung regeneration.
Volume: 30
Issue: 11
Pages: 1486-1502.e9
Publication
First Author: Li G
Year: 2012
Journal: Biochem Biophys Res Commun
Title: Receptor for advanced glycation end products inhibits proliferation in osteoblast through suppression of Wnt, PI3K and ERK signaling.
Volume: 423
Issue: 4
Pages: 684-9
Publication
First Author: Carson C
Year: 2020
Journal: Cell Rep
Title: Brown Adipose Expansion and Remission of Glycemic Dysfunction in Obese SM/J Mice.
Volume: 33
Issue: 1
Pages: 108237
HT Experiment
Series Id: GSE14242
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
Publication
First Author: Kamei Y
Year: 2010
Journal: Obesity (Silver Spring)
Title: Increased expression of DNA methyltransferase 3a in obese adipose tissue: studies with transgenic mice.
Volume: 18
Issue: 2
Pages: 314-21
Publication
First Author: Tripurani SK
Year: 2018
Journal: Mol Biol Cell
Title: Suppression of Wnt/β-catenin signaling by EGF receptor is required for hair follicle development.
Volume: 29
Issue: 22
Pages: 2784-2799
Publication
First Author: Balli D
Year: 2011
Journal: Cancer Res
Title: Endothelial cell-specific deletion of transcription factor FoxM1 increases urethane-induced lung carcinogenesis.
Volume: 71
Issue: 1
Pages: 40-50
Publication
First Author: Bernichtein S
Year: 2008
Journal: Endocrinology
Title: Adrenal gland tumorigenesis after gonadectomy in mice is a complex genetic trait driven by epistatic loci.
Volume: 149
Issue: 2
Pages: 651-61
Publication  
First Author: Kim BK
Year: 2010
Journal: BMC Genomics
Title: Gene expression profile of the skin in the 'hairpoor' (HrHp) mice by microarray analysis.
Volume: 11
Pages: 640
Publication
First Author: He W
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Exogenously administered secreted frizzled related protein 2 (Sfrp2) reduces fibrosis and improves cardiac function in a rat model of myocardial infarction.
Volume: 107
Issue: 49
Pages: 21110-5
Publication
First Author: Gaur T
Year: 2005
Journal: J Biol Chem
Title: Canonical WNT signaling promotes osteogenesis by directly stimulating Runx2 gene expression.
Volume: 280
Issue: 39
Pages: 33132-40
Publication
First Author: Fromigué O
Year: 2010
Journal: J Biol Chem
Title: Essential role of nuclear factor of activated T cells (NFAT)-mediated Wnt signaling in osteoblast differentiation induced by strontium ranelate.
Volume: 285
Issue: 33
Pages: 25251-8
Publication
First Author: Wang L
Year: 2018
Journal: FASEB J
Title: GSK3-activated STAT5 regulates expression of SFRPs to modulate adipogenesis.
Volume: 32
Issue: 9
Pages: 4714-4726
Publication
First Author: Mosa MH
Year: 2020
Journal: Cancer Res
Title: A Wnt-Induced Phenotypic Switch in Cancer-Associated Fibroblasts Inhibits EMT in Colorectal Cancer.
Volume: 80
Issue: 24
Pages: 5569-5582
Publication
First Author: Vigneron F
Year: 2011
Journal: Cardiovasc Res
Title: GSK-3β at the crossroads in the signalling of heart preconditioning: implication of mTOR and Wnt pathways.
Volume: 90
Issue: 1
Pages: 49-56
Publication
First Author: Yao W
Year: 2010
Journal: J Bone Miner Res
Title: Overexpression of secreted frizzled-related protein 1 inhibits bone formation and attenuates parathyroid hormone bone anabolic effects.
Volume: 25
Issue: 2
Pages: 190-9
Publication
First Author: Calabrese G
Year: 2012
Journal: PLoS Genet
Title: Systems genetic analysis of osteoblast-lineage cells.
Volume: 8
Issue: 12
Pages: e1003150
Publication
First Author: Bernichtein S
Year: 2009
Journal: Mol Cell Endocrinol
Title: Adrenal hyperplasia and tumours in mice in connection with aberrant pituitary-gonadal function.
Volume: 300
Issue: 1-2
Pages: 164-8
Publication
First Author: Haÿ E
Year: 2009
Journal: PLoS One
Title: N-cadherin negatively regulates osteoblast proliferation and survival by antagonizing Wnt, ERK and PI3K/Akt signalling.
Volume: 4
Issue: 12
Pages: e8284
Publication
First Author: Bovolenta P
Year: 2008
Journal: J Cell Sci
Title: Beyond Wnt inhibition: new functions of secreted Frizzled-related proteins in development and disease.
Volume: 121
Issue: Pt 6
Pages: 737-46
Publication
First Author: Bhat RA
Year: 2007
Journal: J Cell Biochem
Title: Structure-function analysis of secreted frizzled-related protein-1 for its Wnt antagonist function.
Volume: 102
Issue: 6
Pages: 1519-28
Publication
First Author: Dann CE
Year: 2001
Journal: Nature
Title: Insights into Wnt binding and signalling from the structures of two Frizzled cysteine-rich domains.
Volume: 412
Issue: 6842
Pages: 86-90