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Search results 901 to 1000 out of 1013 for Tbx2

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Type Details Score
Publication
First Author: Voss AK
Year: 2012
Journal: Dev Cell
Title: MOZ regulates the Tbx1 locus, and Moz mutation partially phenocopies DiGeorge syndrome.
Volume: 23
Issue: 3
Pages: 652-63
Publication  
First Author: Seelan RS
Year: 2021
Journal: Differentiation
Title: Gestational folate deficiency alters embryonic gene expression and cell function.
Volume: 117
Pages: 1-15
Publication
First Author: Song L
Year: 2007
Journal: Circ Res
Title: Myocardial smad4 is essential for cardiogenesis in mouse embryos.
Volume: 101
Issue: 3
Pages: 277-85
Publication  
First Author: Gamart J
Year: 2021
Journal: Development
Title: SMAD4 target genes are part of a transcriptional network that integrates the response to BMP and SHH signaling during early limb bud patterning.
Volume: 148
Issue: 23
Publication  
First Author: López SH
Year: 2018
Journal: Dev Biol
Title: Loss of Tbx3 in murine neural crest reduces enteric glia and causes cleft palate, but does not influence heart development or bowel transit.
Volume: 444 Suppl 1
Pages: S337-S351
Publication
First Author: Mori AD
Year: 2006
Journal: Dev Biol
Title: Tbx5-dependent rheostatic control of cardiac gene expression and morphogenesis.
Volume: 297
Issue: 2
Pages: 566-86
Publication  
First Author: Soussi G
Year: 2024
Journal: Development
Title: TBX3 is essential for establishment of the posterior boundary of anterior genes and upregulation of posterior genes together with HAND2 during the onset of limb bud development.
Volume: 151
Issue: 11
Publication
First Author: Itou J
Year: 2012
Journal: Development
Title: Islet1 regulates establishment of the posterior hindlimb field upstream of the Hand2-Shh morphoregulatory gene network in mouse embryos.
Volume: 139
Issue: 9
Pages: 1620-9
Publication
First Author: Mesbah K
Year: 2008
Journal: Circ Res
Title: Tbx3 is required for outflow tract development.
Volume: 103
Issue: 7
Pages: 743-50
Publication
First Author: Gaston-Massuet C
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Transcription factor 7-like 1 is involved in hypothalamo-pituitary axis development in mice and humans.
Volume: 113
Issue: 5
Pages: E548-57
Publication
First Author: Singh N
Year: 2013
Journal: Dev Biol
Title: Murine craniofacial development requires Hdac3-mediated repression of Msx gene expression.
Volume: 377
Issue: 2
Pages: 333-44
Publication
First Author: Prescott K
Year: 2005
Journal: Hum Genet
Title: Microarray analysis of the Df1 mouse model of the 22q11 deletion syndrome.
Volume: 116
Issue: 6
Pages: 486-96
Publication
First Author: Sun Y
Year: 2022
Journal: Cell Rep
Title: Single-cell transcriptomic landscapes of the otic neuronal lineage at multiple early embryonic ages.
Volume: 38
Issue: 12
Pages: 110542
Publication
First Author: Wu CI
Year: 2012
Journal: Development
Title: Function of Wnt/β-catenin in counteracting Tcf3 repression through the Tcf3-β-catenin interaction.
Volume: 139
Issue: 12
Pages: 2118-29
Publication
First Author: Vijayaraj P
Year: 2012
Journal: Development
Title: Erg is a crucial regulator of endocardial-mesenchymal transformation during cardiac valve morphogenesis.
Volume: 139
Issue: 21
Pages: 3973-85
Publication
First Author: Crippa S
Year: 2011
Journal: J Cell Biol
Title: miR669a and miR669q prevent skeletal muscle differentiation in postnatal cardiac progenitors.
Volume: 193
Issue: 7
Pages: 1197-212
Publication  
First Author: Papoutsi T
Year: 2018
Journal: Development
Title: Bmp2 and Notch cooperate to pattern the embryonic endocardium.
Volume: 145
Issue: 13
Publication
First Author: Santos R
Year: 2016
Journal: PLoS Biol
Title: Conditional Creation and Rescue of Nipbl-Deficiency in Mice Reveals Multiple Determinants of Risk for Congenital Heart Defects.
Volume: 14
Issue: 9
Pages: e2000197
Publication
First Author: Ye B
Year: 2015
Journal: J Mol Cell Cardiol
Title: APC controls asymmetric Wnt/β-catenin signaling and cardiomyocyte proliferation gradient in the heart.
Volume: 89
Issue: Pt B
Pages: 287-96
Publication  
First Author: Li F
Year: 2017
Journal: Mol Cell Biol
Title: ISLET1-Dependent β-Catenin/Hedgehog Signaling Is Required for Outgrowth of the Lower Jaw.
Volume: 37
Issue: 8
Publication
First Author: Thomas PS
Year: 2014
Journal: Dev Biol
Title: AcvR1-mediated BMP signaling in second heart field is required for arterial pole development: implications for myocardial differentiation and regional identity.
Volume: 390
Issue: 2
Pages: 191-207
Publication
First Author: Kong P
Year: 2014
Journal: Hum Mol Genet
Title: Tbx1 is required autonomously for cell survival and fate in the pharyngeal core mesoderm to form the muscles of mastication.
Volume: 23
Issue: 16
Pages: 4215-31
Publication
First Author: Watanabe Y
Year: 2006
Journal: Development
Title: Activation of Notch1 signaling in cardiogenic mesoderm induces abnormal heart morphogenesis in mouse.
Volume: 133
Issue: 9
Pages: 1625-34
Publication
First Author: Prados B
Year: 2018
Journal: Cell Death Dis
Title: Myocardial Bmp2 gain causes ectopic EMT and promotes cardiomyocyte proliferation and immaturity.
Volume: 9
Issue: 3
Pages: 399
Publication
First Author: Cho E
Year: 2018
Journal: J Biol Chem
Title: Cardiac-specific developmental and epigenetic functions of Jarid2 during embryonic development.
Volume: 293
Issue: 30
Pages: 11659-11673
Publication
First Author: Suzuki A
Year: 2008
Journal: Development
Title: Tbx3 controls the fate of hepatic progenitor cells in liver development by suppressing p19ARF expression.
Volume: 135
Issue: 9
Pages: 1589-95
Publication
First Author: Assenza MR
Year: 2018
Journal: Cardiovasc Res
Title: Critical role of phosphodiesterase 2A in mouse congenital heart defects.
Volume: 114
Issue: 6
Pages: 830-845
Publication  
First Author: Kurz J
Year: 2022
Journal: Development
Title: GATA6 is a crucial factor for Myocd expression in the visceral smooth muscle cell differentiation program of the murine ureter.
Volume: 149
Issue: 15
Publication  
First Author: Wang Y
Year: 2018
Journal: J Mol Cell Cardiol
Title: Myocardial β-Catenin-BMP2 signaling promotes mesenchymal cell proliferation during endocardial cushion formation.
Volume: 123
Pages: 150-158
Publication
First Author: Carreno G
Year: 2017
Journal: Development
Title: Hypothalamic sonic hedgehog is required for cell specification and proliferation of LHX3/LHX4 pituitary embryonic precursors.
Volume: 144
Issue: 18
Pages: 3289-3302
Publication
First Author: Uribe V
Year: 2014
Journal: Development
Title: Arid3b is essential for second heart field cell deployment and heart patterning.
Volume: 141
Issue: 21
Pages: 4168-81
Publication
First Author: Zhu Z
Year: 2024
Journal: Adv Sci (Weinh)
Title: Isl Identifies the Extraembryonic Mesodermal/Allantois Progenitors and is Required for Placenta Morphogenesis and Vasculature Formation.
Volume: 11
Issue: 32
Pages: e2400238
Publication
First Author: Combes AN
Year: 2009
Journal: Dev Dyn
Title: Three-dimensional visualization of testis cord morphogenesis, a novel tubulogenic mechanism in development.
Volume: 238
Issue: 5
Pages: 1033-41
Publication
First Author: Lewandowski JP
Year: 2015
Journal: Dev Biol
Title: Spatiotemporal regulation of GLI target genes in the mammalian limb bud.
Volume: 406
Issue: 1
Pages: 92-103
Publication
First Author: Shimogori T
Year: 2010
Journal: Nat Neurosci
Title: A genomic atlas of mouse hypothalamic development.
Volume: 13
Issue: 6
Pages: 767-75
Publication
First Author: Shimizu H
Year: 2013
Journal: PLoS One
Title: The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo.
Volume: 8
Issue: 10
Pages: e75754
Publication
First Author: Memic F
Year: 2018
Journal: Gastroenterology
Title: Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System.
Volume: 154
Issue: 3
Pages: 624-636
Publication
First Author: Tang F
Year: 2011
Journal: PLoS One
Title: Deterministic and stochastic allele specific gene expression in single mouse blastomeres.
Volume: 6
Issue: 6
Pages: e21208
Publication
First Author: Blackshaw S
Year: 2004
Journal: PLoS Biol
Title: Genomic analysis of mouse retinal development.
Volume: 2
Issue: 9
Pages: E247
Publication
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
Publication
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
Publication
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication      
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Protein
Organism: Mus musculus/domesticus
Length: 711  
Fragment?: false
Publication
First Author: Rowley M
Year: 2004
Journal: J Mammary Gland Biol Neoplasia
Title: The role of Tbx2 and Tbx3 in mammary development and tumorigenesis.
Volume: 9
Issue: 2
Pages: 109-18
Publication
First Author: Ribeiro I
Year: 2007
Journal: PLoS One
Title: Tbx2 and Tbx3 regulate the dynamics of cell proliferation during heart remodeling.
Volume: 2
Issue: 4
Pages: e398
HT Experiment  
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
HT Sample
Organism Name: mouse, laboratory
Sex: Female
Age: embryonic day 18.5
Stage: 26
Structure . Name: ureter
Notes: control animals were Cre negative Tbx2 fl/?; Tbx3 fl/?
Curation Status: Curated
HT Sample
Organism Name: mouse, laboratory
Sex: Male
Age: embryonic day 14.5
Stage: 22
Structure . Name: ureter
Notes: control animals were Cre negative Tbx2 fl/?; Tbx3 fl/?
Curation Status: Curated
Protein
Organism: Mus musculus/domesticus
Length: 203  
Fragment?: false
GXD Expression  
Probe: MGI:7707439
Assay Type: RNA in situ
Annotation Date: 2024-08-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1667417
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:7707447
Age: embryonic day 10.5
Note: Expression in dorsal hemisphere of optic cup. Expression domain tightly demarcated within broader Tbx2 expression domain.
Specimen Label: 3F
Detected: true
Specimen Num: 1
Publication
First Author: Liu N
Year: 2018
Journal: Hum Mol Genet
Title: Functional variants in TBX2 are associated with a syndromic cardiovascular and skeletal developmental disorder.
Volume: 27
Issue: 14
Pages: 2454-2465
Allele
Name: transgene insertion 1, Yumiko Saga
Allele Type: Transgenic
Attribute String: Reporter
Allele
Name: hypoxanthine phosphoribosyltransferase 1; targeted mutation 2, Andreas Kispert
Allele Type: Targeted
Attribute String: Conditional ready, Humanized sequence, Inserted expressed sequence, Reporter
Strain
Attribute String: mutant strain, transgenic, congenic
Allele
Name: gene trap ROSA 26, Philippe Soriano; endonuclease-mediated mutation 2, Zhiyong Liu
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, Epitope tag, Inserted expressed sequence, Reporter
HT Experiment  
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
Protein Domain
Type: Domain
Description: This region is found C-terminal to the T-box DNA binding domain in T-box transcription factors 2 and 3, which are highly homologous []. This region may be a transcription activation domain (TAD) and contains two completely conserved residues (S and P) that may be functionally important []. T-box genes are highly conserved and encode transcription factors that are involved in morphogenesis and organogenesis of both invertebrates and vertebrates [, , ]. However, TBX2 is strongly re-expressed in adults which suggests a role in non-developmental processes [].
Allele
Name: T-box 2; targeted mutation 1.1, Vincent M Christoffels
Allele Type: Targeted
Attribute String: Recombinase
Genotype
Symbol: Hprt1/Hprt1<+> Tg(Myh6-cre)2182Mds/?
Background: involves: 129 * FVB/N * NMRI
Zygosity: cn
Has Mutant Allele: true
Strain
Attribute String: endonuclease-mediated mutation, mutant stock
Genotype
Symbol: Tbx2/Tbx2
Background: involves: 129P2/OlaHsd * NMRI
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Tbx2/Tbx2<+>
Background: involves: 129P2/OlaHsd * NMRI
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Tbx2/Tbx2
Background: involves: 129P2/OlaHsd * FVB
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Tbx2/Tbx2
Background: involves: 129P2/OlaHsd
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Tbx2/Tbx2<+> Tbx3/Tbx3
Background: involves: 129P2/OlaHsd * FVB/N * NMRI
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Tbx2/Tbx2 Tbx3/Tbx3<+>
Background: involves: 129P2/OlaHsd * FVB/N * NMRI
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Tbx2/Tbx2<+> Tbx3/Tbx3<+>
Background: involves: 129P2/OlaHsd * FVB/N * NMRI
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Tbx2/Tbx2 Tbx3/Tbx3
Background: involves: 129P2/OlaHsd * FVB/N
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Tbx2/Tbx2 Tbx3/Tbx3
Background: involves: 129P2/OlaHsd
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Tbx2/Tbx2 Tbx20/Tbx20
Background: involves: 129P2/OlaHsd * 129S1/SvImJ
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Yi CH
Year: 2000
Journal: Genomics
Title: Virtual cloning and physical mapping of a human T-box gene, TBX4.
Volume: 67
Issue: 1
Pages: 92-5
Publication
First Author: Kumar S
Year: 2011
Journal: Mol Cell Biol
Title: A pathway for the control of anoikis sensitivity by E-cadherin and epithelial-to-mesenchymal transition.
Volume: 31
Issue: 19
Pages: 4036-51