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Search results 901 to 1000 out of 1057 for Ttr

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Hits by Pathway

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Hits by Strain

Type Details Score
Strain
MGI:6148929 | B6.Cg-Tg(Ttr-Hes6)1Ital/Flmg
Attribute String: mutant strain, transgenic
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Strain
MGI:6354090 | STOCK Tg(Mt1-TTR)MPA56Hsas Tg(Mt1-TTR)MPA59Hsas Tg(Mt1-TTR)MPA60Hsas/HsasRbrc
Attribute String: transgenic, mutant stock
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Strain
MGI:6354093 | STOCK Tg(Mt1-TTR)MPA63Hsas Tg(Mt1-TTR)MPA64Hsas Tg(Mt1-TTR)MPA65Hsas/HsasRbrc
Attribute String: transgenic, mutant stock
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Strain
MGI:6354094 | STOCK Tg(Mt1-TTR)MPA64Hsas Tg(Mt1-TTR)MPA65Hsas Tg(Mt1-TTR)MPA66Hsas/HsasRbrc
Attribute String: transgenic, mutant stock
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Allele
Igs2<em2(Alb-TTR*V50M)Cya> | MGI:7657267
Name: intergenic site 2; endonuclease-mediated mutation 2, Cyagen Biosciences
Allele Type: Endonuclease-mediated
Attribute String: Inserted expressed sequence
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Strain
MGI:7657630 | C57BL/6N-Ttr<tm1(TTR)Cya>/Cya
Attribute String: coisogenic, targeted mutation, mutant strain
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Allele
Tg(Ttr-USP22/ESR1)1Ital | MGI:7856687
Name: transgene insertion 1, Iannis Talianidis
Allele Type: Transgenic
Attribute String: Epitope tag, Humanized sequence, Inserted expressed sequence
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Publication
12354101 | J:81049
First Author: Noguchi H
Year: 2002
Journal: Genes Cells
Title: Naso-maxillary deformity due to frontonasal expression of human transthyretin gene in transgenic mice.
Volume: 7
Issue: 10
Pages: 1087-98
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Publication
2482921 | J:341135
First Author: Sasaki H
Year: 1989
Journal: Mol Biol Med
Title: Activity of a metallothionein-transthyretin fusion gene in transgenic mice. Possible effect of plasmid sequences on tissue-specific expression.
Volume: 6
Issue: 4
Pages: 345-53
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Publication
18357510 | J:140274
First Author: Inoue S
Year: 2008
Journal: Transgenic Res
Title: Specific pathogen free conditions prevent transthyretin amyloidosis in mouse models.
Volume: 17
Issue: 5
Pages: 817-26
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Publication
11713303 | J:106084
First Author: Selfridge J
Year: 2001
Journal: Nucleic Acids Res
Title: Correction of liver dysfunction in DNA repair-deficient mice with an ERCC1 transgene.
Volume: 29
Issue: 22
Pages: 4541-50
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Publication
12466203 | J:80586
First Author: Hsia KT
Year: 2003
Journal: Development
Title: DNA repair gene Ercc1 is essential for normal spermatogenesis and oogenesis and for functional integrity of germ cell DNA in the mouse.
Volume: 130
Issue: 2
Pages: 369-78
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Publication
12713813 | J:341303
First Author: Winter AG
Year: 2003
Journal: DNA Repair (Amst)
Title: The repair and recombination enzyme ERCC1 is not required for immunoglobulin class switching.
Volume: 2
Issue: 5
Pages: 561-9
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Publication
27679560 | J:249704
First Author: Liu Z
Year: 2016
Journal: Diabetes
Title: Growth Hormone Control of Hepatic Lipid Metabolism.
Volume: 65
Issue: 12
Pages: 3598-3609
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Allele
Tg(Ttr-Cdkn1a)36Tvd | MGI:2429747
Name: transgene insertion 36, Terry Van Dyke
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Strain
MGI:2665562 | B6.Cg-Tg(Ttr-Cdkn1a)36Tvd/Mmnc
Attribute String: congenic, mutant strain, transgenic
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Strain
MGI:5056482 | B6.Cg-Tg(Ttr-Cdkn1a)36Tvd
Attribute String: congenic, mutant strain, transgenic
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Publication
8595876 | J:31291
First Author: Wu H
Year: 1996
Journal: Genes Dev
Title: Targeted in vivo expression of the cyclin-dependent kinase inhibitor p21 halts hepatocyte cell-cycle progression, postnatal liver development and regeneration.
Volume: 10
Issue: 3
Pages: 245-60
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Publication
10567581 | J:58603
First Author: Ye H
Year: 1999
Journal: Mol Cell Biol
Title: Premature expression of the winged helix transcription factor HFH-11B in regenerating mouse liver accelerates hepatocyte entry into S phase.
Volume: 19
Issue: 12
Pages: 8570-80
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Publication
11391529 | J:81376
First Author: Wang X
Year: 2001
Journal: Hepatology
Title: Earlier expression of the transcription factor HFH-11B diminishes induction of p21(CIP1/WAF1) levels and accelerates mouse hepatocyte entry into S-phase following carbon tetrachloride liver injury.
Volume: 33
Issue: 6
Pages: 1404-14
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Publication
13679865 | J:85966
First Author: Kalinina OA
Year: 2003
Journal: Oncogene
Title: Sustained hepatic expression of FoxM1B in transgenic mice has minimal effects on hepatocellular carcinoma development but increases cell proliferation rates in preneoplastic and early neoplastic lesions.
Volume: 22
Issue: 40
Pages: 6266-76
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Strain
MGI:4456084 | FVB.Cg-Igf1<tm1.1Dlr> Tg(Ttr-IGF1)1Sykr
Attribute String: mutant strain, congenic, targeted mutation, transgenic
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Publication
20200935 | J:169833
First Author: Elis S
Year: 2010
Journal: J Bone Miner Res
Title: Elevated serum levels of IGF-1 are sufficient to establish normal body size and skeletal properties even in the absence of tissue IGF-1.
Volume: 25
Issue: 6
Pages: 1257-66
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Publication
20926579 | J:169499
First Author: Cannata D
Year: 2010
Journal: Endocrinology
Title: Elevated circulating IGF-I promotes mammary gland development and proliferation.
Volume: 151
Issue: 12
Pages: 5751-61
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Publication
19497975 | J:157350
First Author: Wu Y
Year: 2009
Journal: Endocrinology
Title: Elevated levels of insulin-like growth factor (IGF)-I in serum rescue the severe growth retardation of IGF-I null mice.
Volume: 150
Issue: 9
Pages: 4395-403
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Allele
Tg(Ttr-Foxo1)305Dac | MGI:3521642
Name: transgene insertion 305, Domenico Accili
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Ttr-Foxo1)307Dac | MGI:3521643
Name: transgene insertion 307, Domenico Accili
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Publication
18268048 | J:135248
First Author: Moh A
Year: 2008
Journal: Diabetes
Title: STAT3 sensitizes insulin signaling by negatively regulating glycogen synthase kinase-3 beta.
Volume: 57
Issue: 5
Pages: 1227-35
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Allele
Tg(TTR-Igf1)1Jxu | MGI:3771966
Name: transgene insertion 1, Jianming Xu
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Publication
28827407 | J:245627
First Author: Oka M
Year: 2017
Journal: J Cell Sci
Title: Arl8b is required for lysosomal degradation of maternal proteins in the visceral yolk sac endoderm of mouse embryos.
Volume: 130
Issue: 20
Pages: 3568-3577
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Allele
Ttr<tm3(TTR*)Kymm> | MGI:3838183
Name: transthyretin; targeted mutation 3, Ken-ichi Yamamura
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence, RMCE-ready
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Allele
Tg(Ttr-Retn)1Laz | MGI:4462407
Name: transgene insertion 1, Mitchell A Lazar
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Strain
MGI:4462826 | B6.Cg-Tg(Ttr-Retn)1Laz/Mmmh
Attribute String: transgenic, mutant strain, congenic
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Publication
15189975 | J:91890
First Author: Rangwala SM
Year: 2004
Journal: Diabetes
Title: Abnormal glucose homeostasis due to chronic hyperresistinemia.
Volume: 53
Issue: 8
Pages: 1937-41
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Allele
Tg(TTR-INSR)L1Dac | MGI:4831145
Name: transgene insertion L1, Domenico Accili
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(TTR-INSR)L2Dac | MGI:4831146
Name: transgene insertion L2, Dominico Accili
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(TTR-INSR)L3Dac | MGI:4831147
Name: transgene insertion L3, Dominico Accili
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(TTR-INSR)#Dac | MGI:4838213
Name: transgene insertion, Domenico Accili
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Strain
MGI:5004248 | STOCK Tg(Ttr-EGFP)NE84Gsat/Mmucd
Attribute String: mutant stock, transgenic
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Strain
MGI:6333230 | B6;CBA-Ttr<tm2.1(TTR)Kymm>/Imeg
Attribute String: targeted mutation, mutant stock
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Strain
MGI:6333231 | B6;CBA-Ttr<tm2.1(TTR)Kymm>/2Imeg
Attribute String: targeted mutation, mutant stock
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Allele
Ttr<em1(TTR)Kymm> | MGI:6885604
Name: transthyretin; endonuclease-mediated mutation 1, Ken-ichi Yamamura
Allele Type: Endonuclease-mediated
Attribute String: Humanized sequence, Inserted expressed sequence
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Strain
MGI:7657639 | C57BL/6N-Igs2<em2(Alb-TTR*V50M)Cya>/Cya
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Strain
MGI:6335864 | STOCK Tg(Ttr-USP22/ESR1)1Ital/Flmg
Attribute String: mutant strain, transgenic
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Genotype
Genotype
Symbol: Ercc1/Ercc1 Tg(Ttr-Ercc1)17Dwm/?
Background: involves: 129P2/OlaHsd * BALB/c
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Hfe/Hfe Tg(Ttr-Hfe)1Nca/?
Background: involves: 129S6/SvEvTac * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Igf1/Igf1 Tg(Ttr-IGF1)1Sykr/?
Background: FVB.Cg-Igf1 Tg(Ttr-IGF1)1Sykr
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Ttr-Retn)1Laz/?
Background: involves: C57BL/6 * SJL
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Ttr-Cdkn1a)36Tvd/?
Background: B6.Cg-Tg(Ttr-Cdkn1a)36Tvd
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Aurka/Aurka<+> Tg(Ttr-cre)1Hadj/?
Background: involves: 129P2/OlaHsd * C57BL/6J * CBA/J
Zygosity: cn
Has Mutant Allele: true
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Publication
17912366 | J:130019
First Author: Paul C
Year: 2007
Journal: PLoS One
Title: Deletion of genes implicated in protecting the integrity of male germ cells has differential effects on the incidence of DNA breaks and germ cell loss.
Volume: 2
Issue: 10
Pages: e989
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Publication
23456957 | J:233253
First Author: Wu Y
Year: 2013
Journal: J Bone Miner Res
Title: Serum IGF-1 is insufficient to restore skeletal size in the total absence of the growth hormone receptor.
Volume: 28
Issue: 7
Pages: 1575-86
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Publication
16709615 | J:129478
First Author: Liao L
Year: 2006
Journal: Endocrinology
Title: Liver-specific overexpression of the insulin-like growth factor-I enhances somatic growth and partially prevents the effects of growth hormone deficiency.
Volume: 147
Issue: 8
Pages: 3877-88
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Allele
Ttr<tm2(TTR)Kymm> | MGI:3838182
Name: transthyretin; targeted mutation 2, Ken-ichi Yamamura
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence, RMCE-ready
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Strain
MGI:6885749 | C57BL/6-Ttr<em1(TTR)Kymm>/Kymm
Attribute String: mutant strain, coisogenic, endonuclease-mediated mutation
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Genotype
Genotype
Symbol: Tg(Ttr-Foxo1)307Dac/?
Background: involves: C57BL/6J
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Ttr-Foxo1)307Dac/?
Background: involves: FVB * C57BL/6
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rab7/Rab7 Tg(Ttr-cre)1Hadj/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * CBA/J
Zygosity: cn
Has Mutant Allele: true
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Publication
21204266 | J:232313
First Author: Park HJ
Year: 2011
Journal: EMBO Mol Med
Title: Deregulation of FoxM1b leads to tumour metastasis.
Volume: 3
Issue: 1
Pages: 21-34
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Publication
21355094 | J:172826
First Author: Finberg KE
Year: 2011
Journal: Blood
Title: Tmprss6 is a genetic modifier of the Hfe-hemochromatosis phenotype in mice.
Volume: 117
Issue: 17
Pages: 4590-9
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Publication
17660847 | J:128719
First Author: Moh A
Year: 2007
Journal: Lab Invest
Title: Role of STAT3 in liver regeneration: survival, DNA synthesis, inflammatory reaction and liver mass recovery.
Volume: 87
Issue: 10
Pages: 1018-28
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Allele
Tg(TTR-V30M)14Imeg | MGI:3053585
Name: transgene insertion 14, Institute of Molecular Embryology and Genetics
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(TTR-V30M)<dl>14Imeg | MGI:3053710
Name: transgene insertion dl (deleted) 14, Institute of Molecular Embryology and Genetics
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Publication
16644672 | J:108626
First Author: Buteau J
Year: 2006
Journal: Diabetes
Title: Transcription factor FoxO1 mediates glucagon-like peptide-1 effects on pancreatic beta-cell mass.
Volume: 55
Issue: 5
Pages: 1190-6
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Strain
MGI:3838316 | B6.Cg-Ttr<tm2(TTR)Kymm>
Attribute String: targeted mutation, congenic
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Strain
MGI:3838318 | B6.Cg-Ttr<tm3(TTR*)Kymm>
Attribute String: targeted mutation, congenic
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Genotype
Genotype
Symbol: Tg(Ttr-Foxo1)305Dac/?
Background: involves: FVB * C57BL/6
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Stat3/Stat3 Tg(Ttr-cre)10-3Xyfu/?
Background: involves: 129S1/Sv * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ttr/Ttr<+>
Background: B6.Cg-Ttr
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ttr/Ttr
Background: B6.Cg-Ttr
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ttr/Ttr
Background: B6.Cg-Ttr
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Insr/Insr Tg(TTR-INSR)L1Dac/?
Background: involves: 129S4/SvJae * C57BL/6 * FVB
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Insr/Insr Tg(TTR-INSR)L2Dac/?
Background: involves: 129S4/SvJae * C57BL/6 * FVB
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Insr/Insr Tg(TTR-INSR)L3Dac/?
Background: involves: 129S4/SvJae * C57BL/6 * FVB
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Porcn/Porcn<+> Tg(Ttr-cre)1Hadj/?
Background: involves: 129S6/SvEvTac * C57BL/6J * C57BL/6NCr * CBA/J
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Aurka/Aurka Tg(Ttr-cre)1Hadj/?
Background: involves: 129P2/OlaHsd * C57BL/6J * CBA/J
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Itgb1/Itgb1 Tg(Ttr-cre)1Hadj/?
Background: involves: 129X1/SvJ * C57BL/6J * CBA/J
Zygosity: cn
Has Mutant Allele: true
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Publication
18485534 | J:156658
First Author: Santos SD
Year: 2010
Journal: Neurobiol Aging
Title: The heat shock response modulates transthyretin deposition in the peripheral and autonomic nervous systems.
Volume: 31
Issue: 2
Pages: 280-9
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Publication
1992765 | J:80880
First Author: Yi S
Year: 1991
Journal: Am J Pathol
Title: Systemic amyloidosis in transgenic mice carrying the human mutant transthyretin (Met30) gene. Pathologic similarity to human familial amyloidotic polyneuropathy, type I.
Volume: 138
Issue: 2
Pages: 403-12
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Publication
2560117 | J:10319
First Author: Shimada K
Year: 1989
Journal: Mol Biol Med
Title: Transgenic mouse model of familial amyloidotic polyneuropathy.
Volume: 6
Issue: 4
Pages: 333-43
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Publication
1497094 | J:1825
First Author: Murakami T
Year: 1992
Journal: Am J Pathol
Title: Effect of serum amyloid P component level on transthyretin-derived amyloid deposition in a transgenic mouse model of familial amyloidotic polyneuropathy.
Volume: 141
Issue: 2
Pages: 451-6
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Publication
18497885 | J:137715
First Author: Kamagate A
Year: 2008
Journal: J Clin Invest
Title: FoxO1 mediates insulin-dependent regulation of hepatic VLDL production in mice.
Volume: 118
Issue: 6
Pages: 2347-64
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Publication
16997836 | J:129563
First Author: Qu S
Year: 2006
Journal: Endocrinology
Title: Aberrant Forkhead box O1 function is associated with impaired hepatic metabolism.
Volume: 147
Issue: 12
Pages: 5641-52
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Publication
15546000 | J:94423
First Author: Altomonte J
Year: 2004
Journal: J Clin Invest
Title: Foxo1 mediates insulin action on apoC-III and triglyceride metabolism.
Volume: 114
Issue: 10
Pages: 1493-503
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Publication
19342603 | J:164772
First Author: Symons JD
Year: 2009
Journal: Circ Res
Title: Contribution of insulin and Akt1 signaling to endothelial nitric oxide synthase in the regulation of endothelial function and blood pressure.
Volume: 104
Issue: 9
Pages: 1085-94
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Publication
19933841 | J:156389
First Author: Martinez-Jimenez CP
Year: 2010
Journal: Mol Cell Biol
Title: Hepatocyte nuclear factor 4alpha coordinates a transcription factor network regulating hepatic fatty acid metabolism.
Volume: 30
Issue: 3
Pages: 565-77
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Publication
18212051 | J:134212
First Author: Liao L
Year: 2008
Journal: Mol Cell Biol
Title: Steroid receptor coactivator 3 maintains circulating insulin-like growth factor I (IGF-I) by controlling IGF-binding protein 3 expression.
Volume: 28
Issue: 7
Pages: 2460-9
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Publication
20837779 | J:167407
First Author: Schmidt PJ
Year: 2010
Journal: Blood
Title: Hepcidin induction by transgenic overexpression of Hfe does not require the Hfe cytoplasmic tail, but does require hemojuvelin.
Volume: 116
Issue: 25
Pages: 5679-87
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Publication
21540290 | J:174898
First Author: Zerrad-Saadi A
Year: 2011
Journal: Endocrinology
Title: GH receptor plays a major role in liver regeneration through the control of EGFR and ERK1/2 activation.
Volume: 152
Issue: 7
Pages: 2731-41
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Publication
29339473 | J:257760
First Author: Nagaraj K
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Identification of thioredoxin-interacting protein (TXNIP) as a downstream target for IGF1 action.
Volume: 115
Issue: 5
Pages: 1045-1050
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Publication
31442251 | J:284312
First Author: Gustafson JA
Year: 2019
Journal: PLoS One
Title: Calvarial osteoblast gene expression in patients with craniosynostosis leads to novel polygenic mouse model.
Volume: 14
Issue: 8
Pages: e0221402
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Strain
MGI:3053707 | B6;CClea-Tg(TTR-V30M)14Imeg
Attribute String: mutant stock, transgenic
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Strain
MGI:3053706 | C57BL/6-Tg(TTR-V30M)14Imeg
Attribute String: mutant strain, transgenic, coisogenic
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Strain
MGI:3053745 | C57BL/6-Tg(TTR-V30M)<dl>14Imeg
Attribute String: mutant strain, transgenic, coisogenic
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Strain
MGI:6196485 | B6.Cg-Ttr<tm2(TTR)Kymm> Rbp4<tm1(RBP4)Zhel>
Attribute String: congenic, mutant strain, targeted mutation
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Genotype
Genotype
Symbol: Rac1/Rac1 Tg(Ttr-cre)1Hadj/?
Background: involves: 129S4/SvJae * C3H * C57BL/6 * CBA/J
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Arhgef7/Arhgef7 Tg(Ttr-cre)1Hadj/?
Background: involves: C57BL/6J * C57BL/6N * CBA/J
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Ttr-cre)1Hadj/?
Background: involves: 129S4/SvJaeSor * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(CAG-Bgeo/GFP)21Lbe/? Tg(Ttr-cre)1Hadj/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Publication
25524914 | J:247248
First Author: Zemany L
Year: 2015
Journal: Diabetes
Title: Transthyretin Antisense Oligonucleotides Lower Circulating RBP4 Levels and Improve Insulin Sensitivity in Obese Mice.
Volume: 64
Issue: 5
Pages: 1603-14
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