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Search results 9601 to 9700 out of 15062 for F2

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Type Details Score
Publication
First Author: Lamia SN
Year: 2024
Journal: FASEB J
Title: Overexpression of enhanced yellow fluorescent protein fused with Channelrhodopsin-2 causes contractile dysfunction in skeletal muscle.
Volume: 38
Issue: 22
Pages: e70185
Publication
First Author: Hsu W
Year: 2001
Journal: J Cell Biol
Title: Impaired mammary gland and lymphoid development caused by inducible expression of Axin in transgenic mice.
Volume: 155
Issue: 6
Pages: 1055-64
Publication      
First Author: Griffith AJ
Year: 2011
Journal: MGI Direct Data Submission
Title: Tet effector and responder transgenes to regulate Slc26a4 expression
Publication
First Author: Zappulla JP
Year: 2005
Journal: J Exp Med
Title: Mastocytosis in mice expressing human Kit receptor with the activating Asp816Val mutation.
Volume: 202
Issue: 12
Pages: 1635-41
Publication  
First Author: Bisetto S
Year: 2019
Journal: iScience
Title: New Insights into the Lactate Shuttle: Role of MCT4 in the Modulation of the Exercise Capacity.
Volume: 22
Pages: 507-518
Publication
First Author: Whitebirch AC
Year: 2023
Journal: J Neurosci
Title: Reduced Cholecystokinin-Expressing Interneuron Input Contributes to Disinhibition of the Hippocampal CA2 Region in a Mouse Model of Temporal Lobe Epilepsy.
Volume: 43
Issue: 41
Pages: 6930-6949
Publication  
First Author: ElSayed S
Year: 2021
Journal: Front Immunol
Title: Recombinant Human Proteoglycan 4 Regulates Phagocytic Activation of Monocytes and Reduces IL-1β Secretion by Urate Crystal Stimulated Gout PBMCs.
Volume: 12
Pages: 771677
Publication
First Author: Park S
Year: 2020
Journal: Biol Reprod
Title: CRISPR/Cas9-mediated genome-edited mice reveal 10 testis-enriched genes are dispensable for male fecundity.
Volume: 103
Issue: 2
Pages: 195-204
Publication  
First Author: Zhang X
Year: 2021
Journal: J Cell Sci
Title: LRRC23 is a conserved component of the radial spoke that is necessary for sperm motility and male fertility in mice.
Volume: 134
Issue: 20
Publication
First Author: Ainscough JF
Year: 2000
Journal: Mech Dev
Title: Appropriate expression of the mouse H19 gene utilises three or more distinct enhancer regions spread over more than 130 kb.
Volume: 91
Issue: 1-2
Pages: 365-8
Publication
First Author: Rodriguez MR
Year: 2009
Journal: Mamm Genome
Title: A Cmv2 QTL on chromosome X affects MCMV resistance in New Zealand male mice.
Volume: 20
Issue: 7
Pages: 414-23
Publication
First Author: Pizzolla A
Year: 2011
Journal: Eur J Immunol
Title: CD68-expressing cells can prime T cells and initiate autoimmune arthritis in the absence of reactive oxygen species.
Volume: 41
Issue: 2
Pages: 403-12
Publication
First Author: Galliciotti G
Year: 2007
Journal: Am J Pathol
Title: Accumulation of mutant neuroserpin precedes development of clinical symptoms in familial encephalopathy with neuroserpin inclusion bodies.
Volume: 170
Issue: 4
Pages: 1305-13
Publication
First Author: Tobita T
Year: 2019
Journal: J Reprod Dev
Title: Lvrn expression is not critical for mouse placentation.
Volume: 65
Issue: 3
Pages: 239-244
Publication
First Author: López-Luque J
Year: 2016
Journal: Hepatology
Title: Dissecting the role of epidermal growth factor receptor catalytic activity during liver regeneration and hepatocarcinogenesis.
Volume: 63
Issue: 2
Pages: 604-19
Publication
First Author: Oura S
Year: 2022
Journal: Sci Rep
Title: Proximity-dependent biotin labeling in testicular germ cells identified TESMIN-associated proteins.
Volume: 12
Issue: 1
Pages: 22198
Publication
First Author: Larasati T
Year: 2020
Journal: Biol Reprod
Title: Tmprss12 is required for sperm motility and uterotubal junction migration in mice†.
Volume: 103
Issue: 2
Pages: 254-263
Allele
Name: PR domain containing 9; endonuclease-mediated mutation 2, Kenneth Paigen
Allele Type: Endonuclease-mediated
Attribute String: Hypomorph
Publication
First Author: Nozawa K
Year: 2020
Journal: Biol Reprod
Title: Knockout of serine-rich single-pass membrane protein 1 (Ssmem1) causes globozoospermia and sterility in male mice†.
Volume: 103
Issue: 2
Pages: 244-253
Publication
First Author: Brockmann GA
Year: 2009
Journal: Physiol Genomics
Title: Genetic factors contributing to obesity and body weight can act through mechanisms affecting muscle weight, fat weight, or both.
Volume: 36
Issue: 2
Pages: 114-26
Publication  
First Author: Pan Y
Year: 2016
Journal: Sci Rep
Title: Insertion of a knockout-first cassette in Ampd1 gene leads to neonatal death by disruption of neighboring genes expression.
Volume: 6
Pages: 35970
Publication  
First Author: Cochard LM
Year: 2021
Journal: Front Neurosci
Title: Manipulation of EGFR-Induced Signaling for the Recruitment of Quiescent Neural Stem Cells in the Adult Mouse Forebrain.
Volume: 15
Pages: 621076
Allele
Name: transgene insertion 1, Brian L Black
Allele Type: Transgenic
Attribute String: Reporter
Strain
Attribute String: congenic, mutant strain, transgenic
Allele
Name: gasdermin D; endonuclease-mediated mutation 1, Genentech
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Allele
Name: retinal degeneration 24
Allele Type: Spontaneous
Attribute String: Not Specified
Genotype
Symbol: iec/iec
Background: involves: HRS/J * Swiss albino
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: di/di
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
Publication
First Author: Malin D
Year: 2007
Journal: Mol Cell Biol
Title: Forkhead box F1 is essential for migration of mesenchymal cells and directly induces integrin-beta3 expression.
Volume: 27
Issue: 7
Pages: 2486-98
Publication
First Author: Milewski D
Year: 2017
Journal: Oncogene
Title: FoxF1 and FoxF2 transcription factors synergistically promote rhabdomyosarcoma carcinogenesis by repressing transcription of p21Cip1 CDK inhibitor.
Volume: 36
Issue: 6
Pages: 850-862
Publication
First Author: Dudeffant C
Year: 2017
Journal: Sci Rep
Title: Contrast-enhanced MR microscopy of amyloid plaques in five mouse models of amyloidosis and in human Alzheimer's disease brains.
Volume: 7
Issue: 1
Pages: 4955
Publication  
First Author: Findley CA
Year: 2019
Journal: ASN Neuro
Title: Amyloid Beta-Related Alterations to Glutamate Signaling Dynamics During Alzheimer's Disease Progression.
Volume: 11
Pages: 1759091419855541
Publication
First Author: Ishii M
Year: 2015
Journal: Cell Metab
Title: Metabolic and Non-Cognitive Manifestations of Alzheimer's Disease: The Hypothalamus as Both Culprit and Target of Pathology.
Volume: 22
Issue: 5
Pages: 761-76
Publication
First Author: Reinert J
Year: 2014
Journal: J Alzheimers Dis
Title: Aβ38 in the brains of patients with sporadic and familial Alzheimer's disease and transgenic mouse models.
Volume: 39
Issue: 4
Pages: 871-81
Publication
First Author: Bevan RJ
Year: 2020
Journal: Acta Neuropathol Commun
Title: Retinal ganglion cell degeneration correlates with hippocampal spine loss in experimental Alzheimer's disease.
Volume: 8
Issue: 1
Pages: 216
HT Experiment
Series Id: GSE23310
Experiment Type: transcription profiling by array
Study Type: Baseline
Source: ArrayExpress
HT Experiment
Series Id: GSE27236
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
HT Experiment
Series Id: GSE20724
Experiment Type: transcription profiling by array
Study Type: Baseline
Source: ArrayExpress
Publication
First Author: Song G
Year: 2020
Journal: Sci Rep
Title: Multimodal Coherent Imaging of Retinal Biomarkers of Alzheimer's Disease in a Mouse Model.
Volume: 10
Issue: 1
Pages: 7912
Publication
First Author: Vande Vyver M
Year: 2022
Journal: Epilepsia
Title: Higher susceptibility to 6 Hz corneal kindling and lower responsiveness to antiseizure drugs in mouse models of Alzheimer's disease.
Volume: 63
Issue: 10
Pages: 2703-2715
Publication      
First Author: Kong Y
Year: 2024
Journal: Mol Neurobiol
Title: Relationship Between Reactive Astrocytes, by [(18)F]SMBT-1 Imaging, with Amyloid-Beta, Tau, Glucose Metabolism, and TSPO in Mouse Models of Alzheimer's Disease.
Publication  
First Author: Zhao J
Year: 2020
Journal: Front Immunol
Title: Administration of Amyloid Precursor Protein Gene Deleted Mouse ESC-Derived Thymic Epithelial Progenitors Attenuates Alzheimer's Pathology.
Volume: 11
Pages: 1781
Publication
First Author: Cota CD
Year: 2006
Journal: Dev Dyn
Title: Mice with mutations in Mahogunin ring finger-1 (Mgrn1) exhibit abnormal patterning of the left-right axis.
Volume: 235
Issue: 12
Pages: 3438-47
Publication
First Author: Sun K
Year: 2007
Journal: Neurobiol Aging
Title: Mitochondrial dysfunction precedes neurodegeneration in mahogunin (Mgrn1) mutant mice.
Volume: 28
Issue: 12
Pages: 1840-52
Publication
First Author: Jiao J
Year: 2009
Journal: Biochim Biophys Acta
Title: Abnormal regulation of TSG101 in mice with spongiform neurodegeneration.
Volume: 1792
Issue: 10
Pages: 1027-35
Publication
First Author: Jiao J
Year: 2009
Journal: Genesis
Title: Transgenic analysis of the physiological functions of Mahogunin Ring Finger-1 isoforms.
Volume: 47
Issue: 8
Pages: 524-34
Publication
First Author: Fujikura K
Year: 2013
Journal: PLoS One
Title: Kif14 mutation causes severe brain malformation and hypomyelination.
Volume: 8
Issue: 1
Pages: e53490
Publication  
First Author: Yunus J
Year: 2014
Journal: Neuroscience
Title: Cytoarchitecture of the olfactory bulb in the laggard mutant mouse.
Volume: 275
Pages: 259-71
Strain
Attribute String: chemically induced mutation, congenic, mutant strain
Strain
Attribute String: mutant strain, congenic, chemically induced mutation
Strain
Attribute String: chemically induced mutation, mutant stock
Publication  
First Author: LYON MF
Year: 1962
Journal: Z Vererbungsl
Title: A test for mutagenicity of caffeine in mice.
Volume: 93
Pages: 7-13
Publication
First Author: Kong JH
Year: 2020
Journal: Dev Cell
Title: A Membrane-Tethered Ubiquitination Pathway Regulates Hedgehog Signaling and Heart Development.
Volume: 55
Issue: 4
Pages: 432-449.e12
Publication
First Author: Gunn TM
Year: 2019
Journal: Mamm Genome
Title: Chronic and age-dependent effects of the spongiform neurodegeneration-associated MGRN1 E3 ubiquitin ligase on mitochondrial homeostasis.
Volume: 30
Issue: 5-6
Pages: 151-165
Publication  
First Author: Phillips RJS
Year: 1971
Journal: Mouse News Lett
Title: Non-agouti curly (nc)
Volume: 45
Pages: 25
Publication
First Author: Silvius D
Year: 2013
Journal: PLoS One
Title: Levels of the Mahogunin Ring Finger 1 E3 ubiquitin ligase do not influence prion disease.
Volume: 8
Issue: 1
Pages: e55575
Publication
First Author: Matsui R
Year: 2006
Journal: Arterioscler Thromb Vasc Biol
Title: Glucose-6-phosphate dehydrogenase deficiency decreases vascular superoxide and atherosclerotic lesions in apolipoprotein E(-/-) mice.
Volume: 26
Issue: 4
Pages: 910-6
Allele  
Name: atherosclerosis susceptibility QTL 1; C57BL/6J
Allele Type: QTL
Strain
Attribute String: mutant strain, coisogenic, spontaneous mutation
Publication
First Author: Beamer WG
Year: 2000
Journal: Bone
Title: Spontaneous fracture (sfx): a mouse genetic model of defective peripubertal bone formation.
Volume: 27
Issue: 5
Pages: 619-26
Publication
First Author: Mohan S
Year: 2005
Journal: J Bone Miner Res
Title: Spontaneous fractures in the mouse mutant sfx are caused by deletion of the gulonolactone oxidase gene, causing vitamin C deficiency.
Volume: 20
Issue: 9
Pages: 1597-610
Publication
First Author: Lindsey RC
Year: 2019
Journal: PLoS One
Title: Vitamin C effects on 5-hydroxymethylcytosine and gene expression in osteoblasts and chondrocytes: Potential involvement of PHD2.
Volume: 14
Issue: 8
Pages: e0220653
Publication
First Author: Jiao Y
Year: 2005
Journal: Mamm Genome
Title: A deletion causing spontaneous fracture identified from a candidate region of mouse Chromosome 14.
Volume: 16
Issue: 1
Pages: 20-31
Publication
First Author: Phelan SA
Year: 2002
Journal: Mamm Genome
Title: Confirmation and high resolution mapping of an atherosclerosis susceptibility gene in mice on Chromosome 1.
Volume: 13
Issue: 10
Pages: 548-53
Publication
First Author: Paigen B
Year: 1989
Journal: Genetics
Title: Ath-2, a second gene determining atherosclerosis susceptibility and high density lipoprotein levels in mice.
Volume: 122
Issue: 1
Pages: 163-8
Allele  
Name: body weight 1; HRS/J
Allele Type: QTL
Publication
First Author: Gurley KA
Year: 2006
Journal: Am J Hum Genet
Title: Biochemical and genetic analysis of ANK in arthritis and bone disease.
Volume: 79
Issue: 6
Pages: 1017-29
Allele  
Name: atherosclerosis susceptibility QTL 3; C3H/HeJ
Allele Type: QTL
Publication
First Author: Watanabe T
Year: 2009
Journal: PLoS One
Title: Genetic and molecular analysis of wild-derived arrhythmic mice.
Volume: 4
Issue: 1
Pages: e4301
Strain
Attribute String: congenic, mutant strain, spontaneous mutation
Strain
Attribute String: mutant strain, coisogenic, spontaneous mutation
Allele    
Name: atherosclerosis susceptibility QTL 3; C57BL/6J
Genotype
Symbol: Gulo/Gulo
Background: BALB/cBy-Gulo/J
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Pgis1/Pgis1 Pgis2/Pgis2
Background: involves: BALB/c * DBA/2
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Pgis1/Pgis1 Pgis2/Pgis2
Background: involves: BALB/c * DBA/2
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Lmr16/Lmr16 Lmr18/Lmr18
Background: involves: BALB/cHeA * STS/A
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: C1qa/C1qa Sle21<129P2/Ola>/? Sle18/Sle18
Background: involves: 129P2/Ola * 129S/SvEv * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Mgrn1/Mgrn1
Background: C3.Cg-Mgrn1
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Mgrn1/Mgrn1
Background: 129S1.Cg-Mgrn1
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Mgrn1/Mgrn1
Background: involves: 101/H * C3H/HeH
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Arrh2/Arrh2 Arrh3/Arrh3
Background: involves: C57BL/6JJcl * M. m. castaneus
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Kif14/Kif14 Tg(CAG-Kif14)28LTskk/?
Background: involves: 129X1/SvJ * C57BL/6JJmsSlc * C57BL/6NJcl * DBA/2NJcl
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Kif14/Kif14
Background: B6.D2(129X1)-Kif14
Zygosity: hm
Has Mutant Allele: true
Publication
First Author: Kumar S
Year: 2020
Journal: Acta Neuropathol Commun
Title: Phosphorylated Aβ peptides in human Down syndrome brain and different Alzheimer's-like mouse models.
Volume: 8
Issue: 1
Pages: 118
Publication
First Author: Li H
Year: 2018
Journal: Biochem Biophys Res Commun
Title: FTO is involved in Alzheimer's disease by targeting TSC1-mTOR-Tau signaling.
Volume: 498
Issue: 1
Pages: 234-239
Publication  
First Author: Weigel TK
Year: 2023
Journal: Front Aging Neurosci
Title: Altered circadian behavior and light sensing in mouse models of Alzheimer's disease.
Volume: 15
Pages: 1218193
Protein
Organism: Mus musculus/domesticus
Length: 75  
Fragment?: true
Publication
First Author: Lee KN
Year: 2004
Journal: Curr Med Chem Cardiovasc Hematol Agents
Title: Alpha2-antiplasmin: potential therapeutic roles in fibrin survival and removal.
Volume: 2
Issue: 4
Pages: 303-10
Protein Domain
Type: Domain
Description: This is an F1 lobe domain consisting of a ubiquitin like fold found in FERM region of Jak-family tyrosine kinases []. Multidomain JAK molecules interact with receptors through their FERM and SH2-like domains, triggering a series of phosphorylation events, resulting in the activation of their kinase domains []. Overall, the FERM region maintains the typical three-lobed architecture, with an F1 lobe consisting of a ubiquitin-like fold, an F2 lobe consisting of an acyl-CoA binding protein fold, and an F3 lobe consisting of a pleckstrin-homology (PH) fold [].
Protein Domain
Type: Domain
Description: Alpha2-antiplasmin (alpha2AP; plasmin inhibitor; MEROPS identifier I04.023) is the primary inhibitor of plasmin, a proteinase that digests fibrin, the main component of blood clots. Alpha2-antiplasmin forms an inactive 1:1 stoichiometric complex with plasmin. It also rapidly crosslinks to fibrin during blood clotting by activated coagulation factor XIII, and as a consequence fibrin becomes more resistant to fibrinolysis. Therefore alpha2AP is important in modulating the effectiveness and persistence of fibrin with respect to its susceptibility to digestion and removal by plasmin [, ]. Alpha2-antiplasmin corresponds to clade F2 of the serpin superfamily (MEROPS family I4) [, ].
Publication
First Author: Yu W
Year: 2020
Journal: Epilepsia
Title: Gabra2 is a genetic modifier of Scn8a encephalopathy in the mouse.
Volume: 61
Issue: 12
Pages: 2847-2856
Allele  
Name: iasi total atrichia
Allele Type: Spontaneous
Publication
First Author: Kang J
Year: 2009
Journal: Dev Biol
Title: Isl1 is a direct transcriptional target of Forkhead transcription factors in second-heart-field-derived mesoderm.
Volume: 334
Issue: 2
Pages: 513-22
Allele
Name: gasdermin D; endonuclease-mediated mutation, Genentech
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Publication
First Author: Volchuk A
Year: 2020
Journal: Nat Commun
Title: Indirect regulation of HMGB1 release by gasdermin D.
Volume: 11
Issue: 1
Pages: 4561
Publication
First Author: Rosli S
Year: 2023
Journal: Cell Death Dis
Title: Gasdermin D promotes hyperinflammation and immunopathology during severe influenza A virus infection.
Volume: 14
Issue: 11
Pages: 727
Publication
First Author: Bulek K
Year: 2020
Journal: J Clin Invest
Title: Epithelial-derived gasdermin D mediates nonlytic IL-1β release during experimental colitis.
Volume: 130
Issue: 8
Pages: 4218-4234
Allele
Name: transgene insertion 2, Ivan Rodriguez
Allele Type: Transgenic
Attribute String: Recombinase, Reporter
Allele
Name: transgene insertion 4, Ivan Rodriguez
Allele Type: Transgenic
Attribute String: Recombinase, Reporter
Strain
Attribute String: congenic, mutant strain, spontaneous mutation