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Search results 1 to 100 out of 518 for Abcb1a

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0.057s
Type Details Score
Gene
Type: gene
Organism: rat
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Zhang G
Year: 2008
Journal: Exp Anim
Title: Senescence-Accelerated Mouse (SAM) strains have a spontaneous mutation in the Abcb1a gene.
Volume: 57
Issue: 4
Pages: 413-7
Publication
First Author: Carrier I
Year: 2008
Journal: FEBS J
Title: Investigating the role of the invariant carboxylate residues E552 and E1197 in the catalytic activity of Abcb1a (mouse Mdr3).
Volume: 275
Issue: 13
Pages: 3312-24
Publication
First Author: Li J
Year: 2017
Journal: Food Chem Toxicol
Title: Abcb1a but not Abcg2 played a predominant role in limiting the brain distribution of Huperzine A in mice.
Volume: 107
Issue: Pt A
Pages: 68-73
Publication
First Author: Kalabis GM
Year: 2005
Journal: Biol Reprod
Title: Multidrug resistance phosphoglycoprotein (ABCB1) in the mouse placenta: fetal protection.
Volume: 73
Issue: 4
Pages: 591-7
Publication
First Author: Margier M
Year: 2019
Journal: FASEB J
Title: ABCB1 (P-glycoprotein) regulates vitamin D absorption and contributes to its transintestinal efflux.
Volume: 33
Issue: 2
Pages: 2084-2094
Publication
First Author: Izawa A
Year: 2010
Journal: Biochem Biophys Res Commun
Title: A novel in vivo regulatory role of P-glycoprotein in alloimmunity.
Volume: 394
Issue: 3
Pages: 646-52
Publication
First Author: Uhr M
Year: 2003
Journal: Biol Psychiatry
Title: Differential enhancement of antidepressant penetration into the brain in mice with abcb1ab (mdr1ab) P-glycoprotein gene disruption.
Volume: 54
Issue: 8
Pages: 840-6
Publication
First Author: Huls M
Year: 2007
Journal: Kidney Int
Title: P-glycoprotein-deficient mice have proximal tubule dysfunction but are protected against ischemic renal injury.
Volume: 72
Issue: 10
Pages: 1233-41
Publication
First Author: Müller MB
Year: 2003
Journal: Neuropsychopharmacology
Title: ABCB1 (MDR1)-type P-glycoproteins at the blood-brain barrier modulate the activity of the hypothalamic-pituitary-adrenocortical system: implications for affective disorder.
Volume: 28
Issue: 11
Pages: 1991-9
Publication
First Author: Foucaud-Vignault M
Year: 2011
Journal: PLoS One
Title: P-glycoprotein dysfunction contributes to hepatic steatosis and obesity in mice.
Volume: 6
Issue: 9
Pages: e23614
Publication
First Author: Kannan P
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Lysosomal trapping of a radiolabeled substrate of P-glycoprotein as a mechanism for signal amplification in PET.
Volume: 108
Issue: 6
Pages: 2593-8
Publication
First Author: Tsuruoka S
Year: 2001
Journal: J Am Soc Nephrol
Title: P-glycoprotein-mediated drug secretion in mouse proximal tubule perfused in vitro.
Volume: 12
Issue: 1
Pages: 177-81
Publication
First Author: Miyata Y
Year: 2001
Journal: Am J Physiol Renal Physiol
Title: Effects of P-glycoprotein on cell volume regulation in mouse proximal tubule.
Volume: 280
Issue: 5
Pages: F829-37
Publication
First Author: Smit JW
Year: 1999
Journal: J Clin Invest
Title: Absence or pharmacological blocking of placental P-glycoprotein profoundly increases fetal drug exposure.
Volume: 104
Issue: 10
Pages: 1441-7
Publication
First Author: Bardelmeijer HA
Year: 2000
Journal: Clin Cancer Res
Title: Increased oral bioavailability of paclitaxel by GF120918 in mice through selective modulation of P-glycoprotein.
Volume: 6
Issue: 11
Pages: 4416-21
Publication
First Author: Miyata Y
Year: 2002
Journal: Am J Physiol Renal Physiol
Title: P-gp-induced modulation of regulatory volume increase occurs via PKC in mouse proximal tubule.
Volume: 282
Issue: 1
Pages: F65-76
Publication
First Author: Kooij G
Year: 2009
Journal: PLoS One
Title: P-glycoprotein acts as an immunomodulator during neuroinflammation.
Volume: 4
Issue: 12
Pages: e8212
Publication
First Author: Gollapudi S
Year: 2000
Journal: Genes Immun
Title: P-glycoprotein (encoded by multidrug resistance genes) is not required for interleukin-2 secretion in mice and humans.
Volume: 1
Issue: 6
Pages: 371-9
Publication
First Author: Eisenbraun MD
Year: 2000
Journal: Dev Comp Immunol
Title: Altered development of intestinal intraepithelial lymphocytes in P-glycoprotein-deficient mice.
Volume: 24
Issue: 8
Pages: 783-95
Publication
First Author: Israeli D
Year: 2007
Journal: Exp Cell Res
Title: Expression of mdr1 is required for efficient long term regeneration of dystrophic muscle.
Volume: 313
Issue: 11
Pages: 2438-50
Publication
First Author: Jin M
Year: 2006
Journal: Biochem Pharmacol
Title: Site-dependent contributions of P-glycoprotein and CYP3A to cyclosporin A absorption, and effect of dexamethasone in small intestine of mice.
Volume: 72
Issue: 8
Pages: 1042-50
Publication
First Author: Schuetz EG
Year: 2000
Journal: Mol Pharmacol
Title: Altered expression of hepatic cytochromes P-450 in mice deficient in one or more mdr1 genes.
Volume: 57
Issue: 1
Pages: 188-97
Publication
First Author: Wen X
Year: 2014
Journal: Toxicol Sci
Title: MDR1 transporter protects against paraquat-induced toxicity in human and mouse proximal tubule cells.
Volume: 141
Issue: 2
Pages: 475-83
Publication
First Author: Thompson SJ
Year: 2000
Journal: Anesthesiology
Title: Opiate-induced analgesia is increased and prolonged in mice lacking P-glycoprotein.
Volume: 92
Issue: 5
Pages: 1392-9
Publication
First Author: Johnson DR
Year: 2001
Journal: Cancer Res
Title: The pharmacological phenotype of combined multidrug-resistance mdr1a/1b- and mrp1-deficient mice.
Volume: 61
Issue: 4
Pages: 1469-76
Publication
First Author: Cho HY
Year: 2010
Journal: Neuroscience
Title: Influence of ABCB1 genetic polymorphisms on the pharmacokinetics of levosulpiride in healthy subjects.
Volume: 169
Issue: 1
Pages: 378-87
Publication
First Author: Perry A
Year: 2019
Journal: G3 (Bethesda)
Title: Long-Term Combinatorial Exposure to Trichloroethylene and Inorganic Arsenic in Genetically Heterogeneous Mice Results in Renal Tubular Damage and Cancer-Associated Molecular Changes.
Volume: 9
Issue: 5
Pages: 1729-1737
Publication
First Author: Smit JW
Year: 1998
Journal: Br J Pharmacol
Title: Hepatobiliary and intestinal clearance of amphiphilic cationic drugs in mice in which both mdr1a and mdr1b genes have been disrupted.
Volume: 124
Issue: 2
Pages: 416-24
Publication
First Author: Tsuruoka S
Year: 2001
Journal: Pflugers Arch
Title: Protein kinase C and phosphatidylinositol 3-kinase independently contribute to P-glycoprotein-mediated drug secretion in the mouse proximal tubule.
Volume: 442
Issue: 3
Pages: 321-8
Publication
First Author: Zou L
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Bacterial metabolism rescues the inhibition of intestinal drug absorption by food and drug additives.
Volume: 117
Issue: 27
Pages: 16009-16018
Publication
First Author: Mason BL
Year: 2008
Journal: Endocrinology
Title: A revised role for P-glycoprotein in the brain distribution of dexamethasone, cortisol, and corticosterone in wild-type and ABCB1A/B-deficient mice.
Volume: 149
Issue: 10
Pages: 5244-53
Publication
First Author: Sawicki WT
Year: 2006
Journal: Gene Expr Patterns
Title: Temporal/spatial expression and efflux activity of ABC transporter, P-glycoprotein/Abcb1 isoforms and Bcrp/Abcg2 during early murine development.
Volume: 6
Issue: 7
Pages: 738-46
Publication  
First Author: Petropoulos S
Year: 2010
Journal: Brain Res
Title: Developmental expression of multidrug resistance phosphoglycoprotein (P-gp) in the mouse fetal brain and glucocorticoid regulation.
Volume: 1357
Pages: 9-18
Publication
First Author: Wijnholds J
Year: 2000
Journal: J Clin Invest
Title: Multidrug resistance protein 1 protects the choroid plexus epithelium and contributes to the blood-cerebrospinal fluid barrier.
Volume: 105
Issue: 3
Pages: 279-85
Publication
First Author: Krohn M
Year: 2015
Journal: Brain
Title: Accumulation of murine amyloid-β mimics early Alzheimer's disease.
Volume: 138
Issue: Pt 8
Pages: 2370-82
Publication
First Author: Cirrito JR
Year: 2005
Journal: J Clin Invest
Title: P-glycoprotein deficiency at the blood-brain barrier increases amyloid-beta deposition in an Alzheimer disease mouse model.
Volume: 115
Issue: 11
Pages: 3285-90
Publication
First Author: Hendrikx JJ
Year: 2013
Journal: Int J Cancer
Title: P-glycoprotein and cytochrome P450 3A act together in restricting the oral bioavailability of paclitaxel.
Volume: 132
Issue: 10
Pages: 2439-47
Publication  
First Author: Chen ML
Year: 2020
Journal: J Exp Med
Title: Physiological expression and function of the MDR1 transporter in cytotoxic T lymphocytes.
Volume: 217
Issue: 5
Publication
First Author: Schinkel AH
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: Normal viability and altered pharmacokinetics in mice lacking mdr1-type (drug-transporting) P-glycoproteins.
Volume: 94
Issue: 8
Pages: 4028-33
Publication
First Author: Leggas M
Year: 2006
Journal: Cancer Res
Title: Gefitinib modulates the function of multiple ATP-binding cassette transporters in vivo.
Volume: 66
Issue: 9
Pages: 4802-7
Publication
First Author: van Waterschoot RA
Year: 2009
Journal: Cancer Res
Title: Absence of both cytochrome P450 3A and P-glycoprotein dramatically increases docetaxel oral bioavailability and risk of intestinal toxicity.
Volume: 69
Issue: 23
Pages: 8996-9002
Publication
First Author: Zhou S
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Bcrp1 gene expression is required for normal numbers of side population stem cells in mice, and confers relative protection to mitoxantrone in hematopoietic cells in vivo.
Volume: 99
Issue: 19
Pages: 12339-44
Publication
First Author: Zamek-Gliszczynski MJ
Year: 2006
Journal: Mol Pharmacol
Title: The important role of Bcrp (Abcg2) in the biliary excretion of sulfate and glucuronide metabolites of acetaminophen, 4-methylumbelliferone, and harmol in mice.
Volume: 70
Issue: 6
Pages: 2127-33
Publication
First Author: Eisenbraun MD
Year: 1999
Journal: J Immunol
Title: mdr1a-encoded P-glycoprotein is not required for peripheral T cell proliferation, cytokine release, or cytotoxic effector function in mice.
Volume: 163
Issue: 5
Pages: 2621-7
Publication  
First Author: Furukawa K
Year: 2024
Journal: Environ Health Prev Med
Title: Role of ABCB1 and ABCB4 in renal and biliary excretion of perfluorooctanoic acid in mice.
Volume: 29
Pages: 21
Publication
First Author: Uhr M
Year: 2008
Journal: Neuron
Title: Polymorphisms in the drug transporter gene ABCB1 predict antidepressant treatment response in depression.
Volume: 57
Issue: 2
Pages: 203-9
Publication
First Author: Vlaming ML
Year: 2006
Journal: J Pharmacol Exp Ther
Title: Carcinogen and anticancer drug transport by Mrp2 in vivo: studies using Mrp2 (Abcc2) knockout mice.
Volume: 318
Issue: 1
Pages: 319-27
Publication
First Author: Frijters CM
Year: 1999
Journal: J Lipid Res
Title: The role of different P-glycoproteins in hepatobiliary secretion of fluorescently labeled short-chain phospholipids.
Volume: 40
Issue: 11
Pages: 1950-8
Publication
First Author: Jaspers JE
Year: 2013
Journal: Cancer Discov
Title: Loss of 53BP1 causes PARP inhibitor resistance in Brca1-mutated mouse mammary tumors.
Volume: 3
Issue: 1
Pages: 68-81
Publication
First Author: Cattelotte J
Year: 2009
Journal: J Neurochem
Title: Changes in dipole membrane potential at the mouse blood-brain barrier enhance the transport of 99mTechnetium Sestamibi more than inhibiting Abcb1, Abcc1, or Abcg2.
Volume: 108
Issue: 3
Pages: 767-75
Publication
First Author: Schumacher T
Year: 2012
Journal: PLoS One
Title: ABC transporters B1, C1 and G2 differentially regulate neuroregeneration in mice.
Volume: 7
Issue: 4
Pages: e35613
Publication
First Author: Okamura T
Year: 2013
Journal: Am J Respir Cell Mol Biol
Title: Imaging of activity of multidrug resistance-associated protein 1 in the lungs.
Volume: 49
Issue: 3
Pages: 335-40
Publication
First Author: Chee YC
Year: 2018
Journal: Dev Cell
Title: Intrinsic Xenobiotic Resistance of the Intestinal Stem Cell Niche.
Volume: 46
Issue: 6
Pages: 681-695.e5
Publication
First Author: Bockor L
Year: 2017
Journal: Hum Mol Genet
Title: Modulation of bilirubin neurotoxicity by the Abcb1 transporter in the Ugt1-/- lethal mouse model of neonatal hyperbilirubinemia.
Volume: 26
Issue: 1
Pages: 145-157
Publication
First Author: Dekkers DW
Year: 1998
Journal: Biochemistry
Title: Transbilayer movement of NBD-labeled phospholipids in red blood cell membranes: outward-directed transport by the multidrug resistance protein 1 (MRP1).
Volume: 37
Issue: 42
Pages: 14833-7
Publication
First Author: Boddupalli CS
Year: 2016
Journal: J Clin Invest
Title: ABC transporters and NR4A1 identify a quiescent subset of tissue-resident memory T cells.
Volume: 126
Issue: 10
Pages: 3905-3916
Publication
First Author: Yamada T
Year: 2003
Journal: Cancer Res
Title: Suppression of intestinal polyposis in Mdr1-deficient ApcMin/+ mice.
Volume: 63
Issue: 5
Pages: 895-901
Publication
First Author: Shen J
Year: 2009
Journal: Cancer Res
Title: Compartment-specific roles of ATP-binding cassette transporters define differential topotecan distribution in brain parenchyma and cerebrospinal fluid.
Volume: 69
Issue: 14
Pages: 5885-92
Publication
First Author: Hindle SJ
Year: 2017
Journal: Cell Rep
Title: Evolutionarily Conserved Roles for Blood-Brain Barrier Xenobiotic Transporters in Endogenous Steroid Partitioning and Behavior.
Volume: 21
Issue: 5
Pages: 1304-1316
Publication
First Author: Gavrilova O
Year: 2007
Journal: Biochim Biophys Acta
Title: In vivo relevance of Mrp2-mediated biliary excretion of the Amanita mushroom toxin demethylphalloin.
Volume: 1768
Issue: 9
Pages: 2070-7
Publication
First Author: Tang SC
Year: 2014
Journal: Int J Cancer
Title: Increased oral availability and brain accumulation of the ALK inhibitor crizotinib by coadministration of the P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) inhibitor elacridar.
Volume: 134
Issue: 6
Pages: 1484-94
Publication
First Author: Breedveld P
Year: 2005
Journal: Cancer Res
Title: The effect of Bcrp1 (Abcg2) on the in vivo pharmacokinetics and brain penetration of imatinib mesylate (Gleevec): implications for the use of breast cancer resistance protein and P-glycoprotein inhibitors to enable the brain penetration of imatinib in patients.
Volume: 65
Issue: 7
Pages: 2577-82
Publication
First Author: Pfister O
Year: 2008
Journal: Circ Res
Title: Role of the ATP-binding cassette transporter Abcg2 in the phenotype and function of cardiac side population cells.
Volume: 103
Issue: 8
Pages: 825-35
Publication
First Author: Kirkinezos IG
Year: 2004
Journal: J Neurochem
Title: An ALS mouse model with a permeable blood-brain barrier benefits from systemic cyclosporine A treatment.
Volume: 88
Issue: 4
Pages: 821-6
Publication  
First Author: Zawatsky CN
Year: 2021
Journal: Front Endocrinol (Lausanne)
Title: Peripheral Hybrid CB1R and iNOS Antagonist MRI-1867 Displays Anti-Fibrotic Efficacy in Bleomycin-Induced Skin Fibrosis.
Volume: 12
Pages: 744857
Publication
First Author: Spiro AS
Year: 2012
Journal: PLoS One
Title: Enhanced brain disposition and effects of Δ9-tetrahydrocannabinol in P-glycoprotein and breast cancer resistance protein knockout mice.
Volume: 7
Issue: 4
Pages: e35937
Publication
First Author: Choi JY
Year: 2016
Journal: Mol Imaging Biol
Title: P-Glycoprotein, not BCRP, Limits the Brain Uptake of [(18)F]Mefway in Rodent Brain.
Volume: 18
Issue: 2
Pages: 267-73
Publication
First Author: Jablonski MR
Year: 2014
Journal: Ann Clin Transl Neurol
Title: Inhibiting drug efflux transporters improves efficacy of ALS therapeutics.
Volume: 1
Issue: 12
Pages: 996-1005
Publication  
First Author: Brayboy LM
Year: 2017
Journal: Reprod Toxicol
Title: Multidrug resistance transporter-1 and breast cancer resistance protein protect against ovarian toxicity, and are essential in ovarian physiology.
Volume: 69
Pages: 121-131
Publication
First Author: Porteous CM
Year: 2013
Journal: Biochim Biophys Acta
Title: P-glycoprotein (Mdr1a/1b) and breast cancer resistance protein (Bcrp) decrease the uptake of hydrophobic alkyl triphenylphosphonium cations by the brain.
Volume: 1830
Issue: 6
Pages: 3458-65
Publication
First Author: Zander SA
Year: 2012
Journal: Cancer Prev Res (Phila)
Title: Lack of ABCG2 shortens latency of BRCA1-deficient mammary tumors and this is not affected by genistein or resveratrol.
Volume: 5
Issue: 8
Pages: 1053-60
Publication
First Author: Yopp AC
Year: 2004
Journal: J Immunol
Title: FTY720-enhanced T cell homing is dependent on CCR2, CCR5, CCR7, and CXCR4: evidence for distinct chemokine compartments.
Volume: 173
Issue: 2
Pages: 855-65
Publication
First Author: Wang Y
Year: 2020
Journal: Br J Pharmacol
Title: OATP1A/1B, CYP3A, ABCB1, and ABCG2 limit oral availability of the NTRK inhibitor larotrectinib, while ABCB1 and ABCG2 also restrict its brain accumulation.
Volume: 177
Issue: 13
Pages: 3060-3074
Publication
First Author: Tam J
Year: 2010
Journal: J Clin Invest
Title: Peripheral CB1 cannabinoid receptor blockade improves cardiometabolic risk in mouse models of obesity.
Volume: 120
Issue: 8
Pages: 2953-66
Publication  
First Author: Foran E
Year: 2016
Journal: Neurobiol Dis
Title: CNS uptake of bortezomib is enhanced by P-glycoprotein inhibition: implications for spinal muscular atrophy.
Volume: 88
Pages: 118-24
Publication
First Author: Krohn M
Year: 2011
Journal: J Clin Invest
Title: Cerebral amyloid-β proteostasis is regulated by the membrane transport protein ABCC1 in mice.
Volume: 121
Issue: 10
Pages: 3924-31
Publication
First Author: Cao W
Year: 2017
Journal: Immunity
Title: The Xenobiotic Transporter Mdr1 Enforces T Cell Homeostasis in the Presence of Intestinal Bile Acids.
Volume: 47
Issue: 6
Pages: 1182-1196.e10
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63