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Search results 1 to 100 out of 990 for Ace2

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
GXD Expression
Probe: MGI:1579505
Assay Type: RNA in situ
Annotation Date: 2009-01-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3274322
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3826156
Age: embryonic day 14.5
Image: Additional file 4 Ace2
Note: Expression was in the vasculature of the pancreas.
Specimen Label: Additional file 4 Ace2
Detected: true
Specimen Num: 1
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Publication    
First Author: Cao X
Year: 2022
Journal: Elife
Title: ACE2 pathway regulates thermogenesis and energy metabolism.
Volume: 11
Publication
First Author: Jia H
Year: 2020
Journal: Nat Commun
Title: ACE2 mouse models: a toolbox for cardiovascular and pulmonary research.
Volume: 11
Issue: 1
Pages: 5165
Publication
First Author: Wysocki J
Year: 2006
Journal: Diabetes
Title: ACE and ACE2 activity in diabetic mice.
Volume: 55
Issue: 7
Pages: 2132-9
Publication
First Author: Qin WH
Year: 2021
Journal: Cell Mol Gastroenterol Hepatol
Title: Gut ACE2 Expression, Tryptophan Deficiency, and Inflammatory Responses The Potential Connection That Should Not Be Ignored During SARS-CoV-2 Infection.
Volume: 12
Issue: 4
Pages: 1514-1516.e4
Publication
First Author: Wysocki J
Year: 2013
Journal: Am J Physiol Renal Physiol
Title: Regulation of urinary ACE2 in diabetic mice.
Volume: 305
Issue: 4
Pages: F600-11
Publication
First Author: Fang F
Year: 2013
Journal: PLoS One
Title: Loss of ACE2 exacerbates murine renal ischemia-reperfusion injury.
Volume: 8
Issue: 8
Pages: e71433
Publication
First Author: Bernardi S
Year: 2015
Journal: Metabolism
Title: ACE2 deficiency shifts energy metabolism towards glucose utilization.
Volume: 64
Issue: 3
Pages: 406-15
Publication
First Author: Donoghue M
Year: 2003
Journal: J Mol Cell Cardiol
Title: Heart block, ventricular tachycardia, and sudden death in ACE2 transgenic mice with downregulated connexins.
Volume: 35
Issue: 9
Pages: 1043-53
Publication
First Author: Yu W
Year: 2020
Journal: Biochem Biophys Res Commun
Title: ACE2 contributes to the maintenance of mouse epithelial barrier function.
Volume: 533
Issue: 4
Pages: 1276-1282
Publication
First Author: Wysocki J
Year: 2014
Journal: Physiol Rep
Title: ACE2 deficiency increases NADPH-mediated oxidative stress in the kidney.
Volume: 2
Issue: 3
Pages: e00264
Publication  
First Author: Li S
Year: 2020
Journal: Drug Des Devel Ther
Title: ACE2 Attenuates Epithelial-Mesenchymal Transition in MLE-12 Cells Induced by Silica.
Volume: 14
Pages: 1547-1559
Publication
First Author: Winkler ES
Year: 2022
Journal: J Virol
Title: SARS-CoV-2 Causes Lung Infection without Severe Disease in Human ACE2 Knock-In Mice.
Volume: 96
Issue: 1
Pages: e0151121
Publication
First Author: Mukerjee S
Year: 2019
Journal: Hypertension
Title: ACE2 and ADAM17 Interaction Regulates the Activity of Presympathetic Neurons.
Volume: 74
Issue: 5
Pages: 1181-1191
Publication
First Author: Sato T
Year: 2013
Journal: J Clin Invest
Title: Apelin is a positive regulator of ACE2 in failing hearts.
Volume: 123
Issue: 12
Pages: 5203-11
Publication
First Author: Singer D
Year: 2012
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Defective intestinal amino acid absorption in Ace2 null mice.
Volume: 303
Issue: 6
Pages: G686-95
Publication
First Author: Hennighausen L
Year: 2020
Journal: Cell Rep
Title: Activation of the SARS-CoV-2 Receptor Ace2 through JAK/STAT-Dependent Enhancers during Pregnancy.
Volume: 32
Issue: 13
Pages: 108199
Publication
First Author: Tang AT
Year: 2023
Journal: PLoS Biol
Title: Cell-autonomous requirement for ACE2 across organs in lethal mouse SARS-CoV-2 infection.
Volume: 21
Issue: 2
Pages: e3001989
Publication
First Author: Peña Silva RA
Year: 2012
Journal: Stroke
Title: Impact of ACE2 deficiency and oxidative stress on cerebrovascular function with aging.
Volume: 43
Issue: 12
Pages: 3358-63
Publication
First Author: Niu S
Year: 2021
Journal: EMBO J
Title: Molecular basis of cross-species ACE2 interactions with SARS-CoV-2-like viruses of pangolin origin.
Volume: 40
Issue: 16
Pages: e107786
Publication  
First Author: Chen J
Year: 2020
Journal: Aging Cell
Title: Individual variation of the SARS-CoV-2 receptor ACE2 gene expression and regulation.
Volume: 19
Issue: 7
Publication
First Author: Tikellis C
Year: 2008
Journal: Diabetes
Title: ACE2 deficiency modifies renoprotection afforded by ACE inhibition in experimental diabetes.
Volume: 57
Issue: 4
Pages: 1018-25
Publication  
First Author: Adams LE
Year: 2021
Journal: mBio
Title: Critical ACE2 Determinants of SARS-CoV-2 and Group 2B Coronavirus Infection and Replication.
Volume: 12
Issue: 2
Publication
First Author: Camargo SM
Year: 2009
Journal: Gastroenterology
Title: Tissue-specific amino acid transporter partners ACE2 and collectrin differentially interact with hartnup mutations.
Volume: 136
Issue: 3
Pages: 872-82
Publication
First Author: Clotet-Freixas S
Year: 2018
Journal: Lab Invest
Title: Sex dimorphism in ANGII-mediated crosstalk between ACE2 and ACE in diabetic nephropathy.
Volume: 98
Issue: 9
Pages: 1237-1249
Publication  
First Author: Li JX
Year: 2024
Journal: Redox Biol
Title: Myeloid ACE2 protects against septic hypotension and vascular dysfunction through Ang-(1-7)-Mas-mediated macrophage polarization.
Volume: 69
Pages: 103004
Publication
First Author: Jin HY
Year: 2012
Journal: PLoS One
Title: ACE2 deficiency enhances angiotensin II-mediated aortic profilin-1 expression, inflammation and peroxynitrite production.
Volume: 7
Issue: 6
Pages: e38502
Publication
First Author: Hashimoto T
Year: 2012
Journal: Nature
Title: ACE2 links amino acid malnutrition to microbial ecology and intestinal inflammation.
Volume: 487
Issue: 7408
Pages: 477-81
Publication
First Author: Pedersen KB
Year: 2011
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Species-specific inhibitor sensitivity of angiotensin-converting enzyme 2 (ACE2) and its implication for ACE2 activity assays.
Volume: 301
Issue: 5
Pages: R1293-9
Publication
First Author: Liu C
Year: 2019
Journal: Sheng Li Xue Bao
Title: [Establishment of Ace2 knockout mouse model with CRISPR/Cas9 gene targeting technology].
Volume: 71
Issue: 4
Pages: 588-596
Publication
First Author: Patel VB
Year: 2016
Journal: Diabetes
Title: ACE2 Deficiency Worsens Epicardial Adipose Tissue Inflammation and Cardiac Dysfunction in Response to Diet-Induced Obesity.
Volume: 65
Issue: 1
Pages: 85-95
Publication
First Author: Shiota A
Year: 2010
Journal: Hypertens Res
Title: Loss of ACE2 accelerates time-dependent glomerular and tubulointerstitial damage in streptozotocin-induced diabetic mice.
Volume: 33
Issue: 4
Pages: 298-307
Publication
First Author: Moritani T
Year: 2013
Journal: J Am Soc Hypertens
Title: ACE2 deficiency induced perivascular fibrosis and cardiac hypertrophy during postnatal development in mice.
Volume: 7
Issue: 4
Pages: 259-66
Publication
First Author: Snouwaert JN
Year: 2023
Journal: PLoS Pathog
Title: Human ACE2 expression, a major tropism determinant for SARS-CoV-2, is regulated by upstream and intragenic elements.
Volume: 19
Issue: 2
Pages: e1011168
Publication
First Author: Doobay MF
Year: 2007
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Differential expression of neuronal ACE2 in transgenic mice with overexpression of the brain renin-angiotensin system.
Volume: 292
Issue: 1
Pages: R373-81
Publication
First Author: Shoemaker R
Year: 2015
Journal: Am J Physiol Endocrinol Metab
Title: ACE2 deficiency reduces β-cell mass and impairs β-cell proliferation in obese C57BL/6 mice.
Volume: 309
Issue: 7
Pages: E621-31
Publication
First Author: Chodavarapu H
Year: 2016
Journal: Am J Physiol Regul Integr Comp Physiol
Title: High-fat diet-induced glucose dysregulation is independent of changes in islet ACE2 in mice.
Volume: 311
Issue: 6
Pages: R1223-R1233
Publication
First Author: Koester ST
Year: 2021
Journal: PLoS One
Title: Variability in digestive and respiratory tract Ace2 expression is associated with the microbiome.
Volume: 16
Issue: 3
Pages: e0248730
Publication
First Author: Riera M
Year: 2014
Journal: PLoS One
Title: Effect of insulin on ACE2 activity and kidney function in the non-obese diabetic mouse.
Volume: 9
Issue: 1
Pages: e84683
Publication
First Author: Shoemaker R
Year: 2019
Journal: Biol Sex Differ
Title: Adipocyte deficiency of ACE2 increases systolic blood pressures of obese female C57BL/6 mice.
Volume: 10
Issue: 1
Pages: 45
Publication
First Author: Wang W
Year: 2014
Journal: J Mol Med (Berl)
Title: Heterozygote loss of ACE2 is sufficient to increase the susceptibility to heart disease.
Volume: 92
Issue: 8
Pages: 847-58
Publication
First Author: Alghamri MS
Year: 2013
Journal: J Cardiovasc Pharmacol Ther
Title: Enhanced angiotensin II-induced cardiac and aortic remodeling in ACE2 knockout mice.
Volume: 18
Issue: 2
Pages: 138-51
Publication
First Author: Xia H
Year: 2015
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Brain ACE2 overexpression reduces DOCA-salt hypertension independently of endoplasmic reticulum stress.
Volume: 308
Issue: 5
Pages: R370-8
Publication
First Author: Liu A
Year: 2021
Journal: J Pathol
Title: Overexpression of the SARS-CoV-2 receptor ACE2 is induced by cigarette smoke in bronchial and alveolar epithelia.
Volume: 253
Issue: 1
Pages: 17-30
Publication
First Author: Sepe S
Year: 2022
Journal: EMBO Rep
Title: DNA damage response at telomeres boosts the transcription of SARS-CoV-2 receptor ACE2 during aging.
Volume: 23
Issue: 2
Pages: e53658
Publication    
First Author: Gawish R
Year: 2022
Journal: Elife
Title: ACE2 is the critical in vivo receptor for SARS-CoV-2 in a novel COVID-19 mouse model with TNF- and IFNγ-driven immunopathology.
Volume: 11
Publication
First Author: Oudit GY
Year: 2007
Journal: Cardiovasc Res
Title: Angiotensin II-mediated oxidative stress and inflammation mediate the age-dependent cardiomyopathy in ACE2 null mice.
Volume: 75
Issue: 1
Pages: 29-39
Publication
First Author: Takeda M
Year: 2013
Journal: Diabetes
Title: Loss of ACE2 exaggerates high-calorie diet-induced insulin resistance by reduction of GLUT4 in mice.
Volume: 62
Issue: 1
Pages: 223-33
Publication
First Author: Riquelme C
Year: 2014
Journal: PLoS One
Title: ACE2 is augmented in dystrophic skeletal muscle and plays a role in decreasing associated fibrosis.
Volume: 9
Issue: 4
Pages: e93449
Publication
First Author: Choi JY
Year: 2020
Journal: Biochem Biophys Res Commun
Title: Altered COVID-19 receptor ACE2 expression in a higher risk group for cerebrovascular disease and ischemic stroke.
Volume: 528
Issue: 3
Pages: 413-419
Publication
First Author: Gupte M
Year: 2008
Journal: Am J Physiol Regul Integr Comp Physiol
Title: ACE2 is expressed in mouse adipocytes and regulated by a high-fat diet.
Volume: 295
Issue: 3
Pages: R781-8
Publication  
First Author: Roca-Ho H
Year: 2017
Journal: Int J Mol Sci
Title: Characterization of ACE and ACE2 Expression within Different Organs of the NOD Mouse.
Volume: 18
Issue: 3
Publication
First Author: Tikellis C
Year: 2012
Journal: Clin Sci (Lond)
Title: Interaction of diabetes and ACE2 in the pathogenesis of cardiovascular disease in experimental diabetes.
Volume: 123
Issue: 8
Pages: 519-29
Publication
First Author: Thomas MC
Year: 2010
Journal: Circ Res
Title: Genetic Ace2 deficiency accentuates vascular inflammation and atherosclerosis in the ApoE knockout mouse.
Volume: 107
Issue: 7
Pages: 888-97
Publication  
First Author: Vergara A
Year: 2021
Journal: Mol Cell Endocrinol
Title: Effect of ramipril on kidney, lung and heart ACE2 in a diabetic mice model.
Volume: 529
Pages: 111263
Publication
First Author: Dilauro M
Year: 2010
Journal: Am J Physiol Renal Physiol
Title: Effect of ACE2 and angiotensin-(1-7) in a mouse model of early chronic kidney disease.
Volume: 298
Issue: 6
Pages: F1523-32
Publication
First Author: Pedersen KB
Year: 2015
Journal: Endocrinology
Title: Dynamics of ADAM17-Mediated Shedding of ACE2 Applied to Pancreatic Islets of Male db/db Mice.
Volume: 156
Issue: 12
Pages: 4411-25
Publication
First Author: Lin CI
Year: 2018
Journal: Int J Biol Sci
Title: Instillation of particulate matter 2.5 induced acute lung injury and attenuated the injury recovery in ACE2 knockout mice.
Volume: 14
Issue: 3
Pages: 253-265
Publication
First Author: Motta-Santos D
Year: 2016
Journal: Hypertens Res
Title: Effects of ACE2 deficiency on physical performance and physiological adaptations of cardiac and skeletal muscle to exercise.
Volume: 39
Issue: 7
Pages: 506-12
Publication
First Author: Rabelo LA
Year: 2016
Journal: PLoS One
Title: Genetic Deletion of ACE2 Induces Vascular Dysfunction in C57BL/6 Mice: Role of Nitric Oxide Imbalance and Oxidative Stress.
Volume: 11
Issue: 4
Pages: e0150255
Publication
First Author: Liu C
Year: 2015
Journal: Transgenic Res
Title: Generation of outbred Ace2 knockout mice by RNA transfection of TALENs displaying colitis reminiscent pathophysiology and inflammation.
Volume: 24
Issue: 3
Pages: 433-46
Publication      
First Author: Sepe S
Year: 2021
Journal: bioRxiv
Title: DNA damage response at telomeres boost the transcription of SARS-CoV-2 receptor ACE2 during aging.
Publication      
First Author: Deng Q
Year: 2020
Journal: bioRxiv
Title: Targeting androgen regulation of TMPRSS2 and ACE2 as a therapeutic strategy to combat COVID-19.
Publication
First Author: Serfozo P
Year: 2020
Journal: Hypertension
Title: Ang II (Angiotensin II) Conversion to Angiotensin-(1-7) in the Circulation Is POP (Prolyloligopeptidase)-Dependent and ACE2 (Angiotensin-Converting Enzyme 2)-Independent.
Volume: 75
Issue: 1
Pages: 173-182
Publication
First Author: Song J
Year: 2020
Journal: J Med Virol
Title: Systematic analysis of ACE2 and TMPRSS2 expression in salivary glands reveals underlying transmission mechanism caused by SARS-CoV-2.
Volume: 92
Issue: 11
Pages: 2556-2566
Publication  
First Author: Sarver DC
Year: 2021
Journal: Biochem Biophys Res Commun
Title: Obesity alters Ace2 and Tmprss2 expression in lung, trachea, and esophagus in a sex-dependent manner: Implications for COVID-19.
Volume: 538
Pages: 92-96
Publication
First Author: Sodhi CP
Year: 2018
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Attenuation of pulmonary ACE2 activity impairs inactivation of des-Arg9 bradykinin/BKB1R axis and facilitates LPS-induced neutrophil infiltration.
Volume: 314
Issue: 1
Pages: L17-L31
Publication
First Author: Bodiga S
Year: 2011
Journal: Cardiovasc Res
Title: Enhanced susceptibility to biomechanical stress in ACE2 null mice is prevented by loss of the p47(phox) NADPH oxidase subunit.
Volume: 91
Issue: 1
Pages: 151-61
Publication
First Author: Ziegler CGK
Year: 2020
Journal: Cell
Title: SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues.
Volume: 181
Issue: 5
Pages: 1016-1035.e19
Publication  
First Author: Liu Y
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Functional and genetic analysis of viral receptor ACE2 orthologs reveals a broad potential host range of SARS-CoV-2.
Volume: 118
Issue: 12
Publication  
First Author: Sagawa T
Year: 2021
Journal: Environ Res
Title: Exposure to particulate matter upregulates ACE2 and TMPRSS2 expression in the murine lung.
Volume: 195
Pages: 110722
Publication
First Author: Yamaleyeva LM
Year: 2015
Journal: Am J Physiol Endocrinol Metab
Title: Uterine artery dysfunction in pregnant ACE2 knockout mice is associated with placental hypoxia and reduced umbilical blood flow velocity.
Volume: 309
Issue: 1
Pages: E84-94
Publication  
First Author: Thatcher SE
Year: 2012
Journal: Int J Hypertens
Title: Deficiency of ACE2 in Bone-Marrow-Derived Cells Increases Expression of TNF-α in Adipose Stromal Cells and Augments Glucose Intolerance in Obese C57BL/6 Mice.
Volume: 2012
Pages: 762094
Publication
First Author: Xiao L
Year: 2013
Journal: Am J Physiol Cell Physiol
Title: Angiotensin II regulates ACE and ACE2 in neurons through p38 mitogen-activated protein kinase and extracellular signal-regulated kinase 1/2 signaling.
Volume: 304
Issue: 11
Pages: C1073-9
Publication      
First Author: Bilinska K
Year: 2021
Journal: bioRxiv
Title: Expression of the ACE2 virus entry protein in the nervus terminalis suggests an alternative route for brain infection in COVID-19.
Publication
First Author: Sodhi CP
Year: 2019
Journal: J Immunol
Title: A Dynamic Variation of Pulmonary ACE2 Is Required to Modulate Neutrophilic Inflammation in Response to Pseudomonas aeruginosa Lung Infection in Mice.
Volume: 203
Issue: 11
Pages: 3000-3012
Publication  
First Author: Bilinska K
Year: 2021
Journal: Front Cell Neurosci
Title: Expression of the ACE2 Virus Entry Protein in the Nervus Terminalis Reveals the Potential for an Alternative Route to Brain Infection in COVID-19.
Volume: 15
Pages: 674123
Publication      
First Author: Biagioli M
Year: 2021
Journal: bioRxiv
Title: Discovery of a AhR flavonoid agonist that counter-regulates ACE2 expression in rodent models of inflammation and attenuates ACE2 - SARS-CoV2 interaction in vitro.
Publication
First Author: Soni S
Year: 2021
Journal: PLoS One
Title: Comparative analysis of ACE2 protein expression in rodent, non-human primate, and human respiratory tract at baseline and after injury: A conundrum for COVID-19 pathogenesis.
Volume: 16
Issue: 2
Pages: e0247510
Publication
First Author: Hung YH
Year: 2016
Journal: Int J Biol Sci
Title: Alternative Roles of STAT3 and MAPK Signaling Pathways in the MMPs Activation and Progression of Lung Injury Induced by Cigarette Smoke Exposure in ACE2 Knockout Mice.
Volume: 12
Issue: 4
Pages: 454-65
Publication
First Author: Wysocki J
Year: 2020
Journal: J Am Soc Nephrol
Title: Kidney and Lung ACE2 Expression after an ACE Inhibitor or an Ang II Receptor Blocker: Implications for COVID-19.
Volume: 31
Issue: 9
Pages: 1941-1943
Publication
First Author: Bilinska K
Year: 2020
Journal: ACS Chem Neurosci
Title: Expression of the SARS-CoV-2 Entry Proteins, ACE2 and TMPRSS2, in Cells of the Olfactory Epithelium: Identification of Cell Types and Trends with Age.
Volume: 11
Issue: 11
Pages: 1555-1562
Publication
First Author: Qiao J
Year: 2020
Journal: Biochem Biophys Res Commun
Title: The expression of SARS-CoV-2 receptor ACE2 and CD147, and protease TMPRSS2 in human and mouse brain cells and mouse brain tissues.
Volume: 533
Issue: 4
Pages: 867-871
Publication
First Author: Duan Y
Year: 2019
Journal: Circ Res
Title: Bone Marrow-Derived Cells Restore Functional Integrity of the Gut Epithelial and Vascular Barriers in a Model of Diabetes and ACE2 Deficiency.
Volume: 125
Issue: 11
Pages: 969-988
Publication
First Author: Song LN
Year: 2020
Journal: FASEB J
Title: Angiotensin-(1-7), the product of ACE2 ameliorates NAFLD by acting through its receptor Mas to regulate hepatic mitochondrial function and glycolipid metabolism.
Volume: 34
Issue: 12
Pages: 16291-16306
Publication      
First Author: Bao L
Year: 2020
Journal: Nature
Title: The pathogenicity of SARS-CoV-2 in hACE2 transgenic mice.
Publication
First Author: Liu D
Year: 2023
Journal: Proc Natl Acad Sci U S A
Title: Mouse models susceptible to HCoV-229E and HCoV-NL63 and cross protection from challenge with SARS-CoV-2.
Volume: 120
Issue: 4
Pages: e2202820120
Publication  
First Author: Xu F
Year: 2020
Journal: Front Immunol
Title: Genetic Dissection of the Regulatory Mechanisms of Ace2 in the Infected Mouse Lung.
Volume: 11
Pages: 607314