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Search results 1 to 100 out of 200 for Adam2

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0.038s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: rabbit, European
Gene
Type: gene
Organism: guinea pig
Protein Domain
Type: Family
Description: The ADAM2 protein (also known as fertilin beta or PH30 beta; MEROPS identifier M12.950) is a non-peptidase homologue in peptidase family M12. ADAM2 is found in sperm as a heterodimer with ADAM1 (fertilin alpha; MEROPS identifier M12.201) []. The ADAM2 protein consists of a propeptide, a reprolysin-like metallopeptidase domain, a disintegrin domain, a cysteine-rich region, a epidermal growth factor-like domain, a transmembrane region and a cytoplasmic tail []. The disintegrin domain has been shown to be important during fertilization by binding to an oolemmal integrin receptor []. ADAM2 is processed during epididymal maturation to remove N- and C-terminal propeptides [].
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Cho C
Year: 2000
Journal: Dev Biol
Title: Analysis of mouse fertilin in wild-type and fertilin beta(-/-) sperm: evidence for C-terminal modification, alpha/beta dimerization, and lack of essential role of fertilin alpha in sperm-egg fusion.
Volume: 222
Issue: 2
Pages: 289-95
Publication
First Author: Waters SI
Year: 1997
Journal: Biol Reprod
Title: Biochemical and molecular characterization of bovine fertilin alpha and beta (ADAM 1 and ADAM 2): a candidate sperm-egg binding/fusion complex.
Volume: 56
Issue: 5
Pages: 1245-54
Publication
First Author: Bronson RA
Year: 1999
Journal: Mol Hum Reprod
Title: Evidence that a functional fertilin-like ADAM plays a role in human sperm-oolemmal interactions.
Volume: 5
Issue: 5
Pages: 433-40
Protein
Organism: Mus musculus/domesticus
Length: 111  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 111  
Fragment?: true
Publication
First Author: Blobel CP
Year: 1992
Journal: Nature
Title: A potential fusion peptide and an integrin ligand domain in a protein active in sperm-egg fusion.
Volume: 356
Issue: 6366
Pages: 248-52
Publication
First Author: Choi H
Year: 2016
Journal: PLoS One
Title: Characterization of Mammalian ADAM2 and Its Absence from Human Sperm.
Volume: 11
Issue: 6
Pages: e0158321
Publication
First Author: Murase S
Year: 2008
Journal: Eur J Neurosci
Title: ADAM2 promotes migration of neuroblasts in the rostral migratory stream to the olfactory bulb.
Volume: 27
Issue: 7
Pages: 1585-95
Protein
Organism: Mus musculus/domesticus
Length: 735  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 735  
Fragment?: true
Publication
First Author: Stein KK
Year: 2005
Journal: Biol Reprod
Title: Defects in secretory pathway trafficking during sperm development in Adam2 knockout mice.
Volume: 73
Issue: 5
Pages: 1032-8
Publication
First Author: Desiderio UV
Year: 2010
Journal: PLoS One
Title: ADAM2 interactions with mouse eggs and cell lines expressing α4/α9 (ITGA4/ITGA9) integrins: implications for integrin-based adhesion and fertilization.
Volume: 5
Issue: 10
Pages: e13744
Publication
First Author: Kim E
Year: 2006
Journal: J Biol Chem
Title: Mouse sperm lacking ADAM1b/ADAM2 fertilin can fuse with the egg plasma membrane and effect fertilization.
Volume: 281
Issue: 9
Pages: 5634-9
Publication
First Author: Nishimura H
Year: 2007
Journal: J Biol Chem
Title: Identification of an ADAM2-ADAM3 complex on the surface of mouse testicular germ cells and cauda epididymal sperm.
Volume: 282
Issue: 24
Pages: 17900-7
Publication
First Author: Han C
Year: 2009
Journal: Biol Reprod
Title: Comprehensive analysis of reproductive ADAMs: relationship of ADAM4 and ADAM6 with an ADAM complex required for fertilization in mice.
Volume: 80
Issue: 5
Pages: 1001-8
Publication
First Author: Kim T
Year: 2006
Journal: Biol Reprod
Title: Expression and relationship of male reproductive ADAMs in mouse.
Volume: 74
Issue: 4
Pages: 744-50
Publication
First Author: Choi H
Year: 2015
Journal: Biol Reprod
Title: Reduced Fertility and Altered Epididymal and Sperm Integrity in Mice Lacking ADAM7.
Volume: 93
Issue: 3
Pages: 70
Publication
First Author: Nishimura H
Year: 2004
Journal: J Biol Chem
Title: Possible function of the ADAM1a/ADAM2 Fertilin complex in the appearance of ADAM3 on the sperm surface.
Volume: 279
Issue: 33
Pages: 34957-62
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication  
First Author: Evans JP
Year: 1995
Journal: J Cell Sci
Title: Mouse sperm-egg plasma membrane interactions: analysis of roles of egg integrins and the mouse sperm homologue of PH-30 (fertilin) beta.
Volume: 108 ( Pt 10)
Pages: 3267-78
Publication
First Author: Cho C
Year: 1998
Journal: Science
Title: Fertilization defects in sperm from mice lacking fertilin beta.
Volume: 281
Issue: 5384
Pages: 1857-9
Publication
First Author: Zhu X
Year: 2000
Journal: J Biol Chem
Title: Identification of key functional amino acids of the mouse fertilin beta (ADAM2) disintegrin loop for cell-cell adhesion during fertilization.
Volume: 275
Issue: 11
Pages: 7677-83
Publication
First Author: Gupta SK
Year: 1996
Journal: Biochem Biophys Res Commun
Title: Molecular cloning of the human fertilin beta subunit.
Volume: 224
Issue: 2
Pages: 318-26
Publication
First Author: Hardy CM
Year: 1996
Journal: Mol Reprod Dev
Title: Cloning and expression of recombinant rabbit fertilin.
Volume: 45
Issue: 2
Pages: 107-16
Publication
First Author: Vidaeus CM
Year: 1997
Journal: Mol Reprod Dev
Title: Human fertilin beta: identification, characterization, and chromosomal mapping of an ADAM gene family member.
Volume: 46
Issue: 3
Pages: 363-9
Publication
First Author: Evans JP
Year: 1997
Journal: Dev Biol
Title: Characterization of the binding of recombinant mouse sperm fertilin beta subunit to mouse eggs: evidence for adhesive activity via an egg beta1 integrin-mediated interaction.
Volume: 187
Issue: 1
Pages: 79-93
Publication
First Author: Frayne J
Year: 1999
Journal: Bioessays
Title: Mammalian sperm-egg recognition: does fertilin beta have a major role to play?
Volume: 21
Issue: 3
Pages: 183-7
Publication
First Author: Bigler D
Year: 1997
Journal: Trends Cell Biol
Title: A model for sperm-egg binding and fusion based on ADAMs and integrins.
Volume: 7
Issue: 6
Pages: 220-5
GXD Expression    
Probe: MGI:1204988
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:1204990
Age: postnatal week 6-8
Image: st96_352
Specimen Label: None
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:1204988
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:1204990
Age: postnatal week 6-8
Image: st96_352
Specimen Label: None
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:1204988
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3284528
Stage: TS28
Assay Id: MGI:1204990
Age: postnatal week 6-8
Image: st96_352
Specimen Label: None
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:1204988
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Pooled
Emaps: EMAPS:1697428
Stage: TS28
Assay Id: MGI:1204990
Age: postnatal week 6-8
Image: st96_352
Specimen Label: None
Detected: false
Specimen Num: 4
GXD Expression    
Probe: MGI:1204988
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Pooled
Emaps: EMAPS:1754928
Stage: TS28
Assay Id: MGI:1204990
Age: postnatal week 6-8
Image: st96_352
Specimen Label: None
Detected: false
Specimen Num: 5
GXD Expression    
Probe: MGI:1204988
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3280928
Stage: TS28
Assay Id: MGI:1204990
Age: postnatal week 6-8
Image: st96_352
Specimen Label: None
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:1204988
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Pooled
Emaps: EMAPS:1778728
Stage: TS28
Assay Id: MGI:1204990
Age: postnatal week 6-8
Image: st96_352
Specimen Label: None
Detected: false
Specimen Num: 7
GXD Expression    
Probe: MGI:1204988
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1757728
Stage: TS28
Assay Id: MGI:1204990
Age: postnatal week 6-8
Image: st96_352
Specimen Label: None
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:1204988
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Pooled
Emaps: EMAPS:3599828
Stage: TS28
Assay Id: MGI:1204990
Age: postnatal week 6-8
Image: st96_352
Specimen Label: None
Detected: false
Specimen Num: 9
GXD Expression    
Probe: MGI:1204988
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1619828
Stage: TS28
Assay Id: MGI:1204990
Age: postnatal week 6-8
Image: st96_352
Specimen Label: None
Detected: true
Specimen Num: 10
GXD Expression    
Probe: MGI:1204988
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:1204990
Age: postnatal week 6-8
Image: st96_352
Specimen Label: None
Detected: true
Specimen Num: 11
GXD Expression    
Probe: MGI:1204988
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Pooled
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:1204990
Age: postnatal week 6-8
Image: st96_352
Specimen Label: None
Detected: false
Specimen Num: 12
GXD Expression    
Probe: MGI:1204988
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Pooled
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:1204990
Age: postnatal week 6-8
Image: st96_352
Specimen Label: None
Detected: false
Specimen Num: 13
GXD Expression    
Probe: MGI:1204988
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Pooled
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:1204990
Age: postnatal week 6-8
Image: st96_352
Specimen Label: None
Detected: false
Specimen Num: 14
GXD Expression    
Probe: MGI:1204988
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Pooled
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:1204990
Age: postnatal week 6-8
Image: st96_352
Specimen Label: None
Detected: false
Specimen Num: 15
GXD Expression    
Probe: MGI:1204988
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Pooled
Emaps: EMAPS:1720228
Stage: TS28
Assay Id: MGI:1204990
Age: postnatal week 6-8
Image: st96_352
Specimen Label: None
Detected: false
Specimen Num: 16
GXD Expression    
Probe: MGI:1204988
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Pooled
Emaps: EMAPS:1750328
Stage: TS28
Assay Id: MGI:1204990
Age: postnatal week 6-8
Image: st96_352
Specimen Label: None
Detected: false
Specimen Num: 17
GXD Expression    
Probe: MGI:1204988
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:1204990
Age: postnatal week 6-8
Image: st96_352
Specimen Label: None
Detected: true
Specimen Num: 18
GXD Expression    
Probe: MGI:1204988
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1832128
Stage: TS28
Assay Id: MGI:1204990
Age: postnatal week 6-8
Image: st96_352
Specimen Label: None
Detected: true
Specimen Num: 19
GXD Expression    
Probe: MGI:1204988
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Pooled
Emaps: EMAPS:1842628
Stage: TS28
Assay Id: MGI:1204990
Age: postnatal week 6-8
Image: st96_352
Specimen Label: None
Detected: false
Specimen Num: 20
GXD Expression    
Probe: MGI:1204988
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Pooled
Emaps: EMAPS:1752528
Stage: TS28
Assay Id: MGI:1204990
Age: postnatal week 6-8
Image: st96_352
Specimen Label: None
Detected: false
Specimen Num: 21
GXD Expression    
Probe: MGI:1204988
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Pooled
Emaps: EMAPS:3511228
Stage: TS28
Assay Id: MGI:1204990
Age: postnatal week 6-8
Image: st96_352
Specimen Label: None
Detected: false
Specimen Num: 22
GXD Expression    
Probe: MGI:1204988
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Pooled
Emaps: EMAPS:1914328
Stage: TS28
Assay Id: MGI:1204990
Age: postnatal week 6-8
Image: st96_352
Specimen Label: None
Detected: false
Specimen Num: 23
GXD Expression    
Probe: MGI:1204988
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Pooled
Emaps: EMAPS:1742828
Stage: TS28
Assay Id: MGI:1204990
Age: postnatal week 6-8
Image: st96_352
Specimen Label: None
Detected: false
Specimen Num: 24
GXD Expression    
Probe: MGI:1204988
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Pooled
Emaps: EMAPS:3288928
Stage: TS28
Assay Id: MGI:1204990
Age: postnatal week 6-8
Image: st96_352
Specimen Label: None
Detected: false
Specimen Num: 25
GXD Expression    
Probe: MGI:1204988
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Pooled
Emaps: EMAPS:1718528
Stage: TS28
Assay Id: MGI:1204990
Age: postnatal week 6-8
Image: st96_352
Specimen Label: None
Detected: false
Specimen Num: 26
GXD Expression    
Probe: MGI:1204988
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Pooled
Emaps: EMAPS:1775128
Stage: TS28
Assay Id: MGI:1204990
Age: postnatal week 6-8
Image: st96_352
Specimen Label: None
Detected: false
Specimen Num: 27
GXD Expression    
Probe: MGI:1204988
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Pooled
Emaps: EMAPS:1683328
Stage: TS28
Assay Id: MGI:1204990
Age: postnatal week 6-8
Image: st96_352
Specimen Label: None
Detected: false
Specimen Num: 28
GXD Expression    
Probe: MGI:1204988
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Pooled
Emaps: EMAPS:1788628
Stage: TS28
Assay Id: MGI:1204990
Age: postnatal week 6-8
Image: st96_352
Specimen Label: None
Detected: false
Specimen Num: 29
GXD Expression    
Probe: MGI:1204988
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Pooled
Emaps: EMAPS:1789128
Stage: TS28
Assay Id: MGI:1204990
Age: postnatal week 6-8
Image: st96_352
Specimen Label: None
Detected: false
Specimen Num: 30
GXD Expression    
Probe: MGI:1204988
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Pooled
Emaps: EMAPS:1885228
Stage: TS28
Assay Id: MGI:1204990
Age: postnatal week 6-8
Image: st96_352
Specimen Label: None
Detected: false
Specimen Num: 31
GXD Expression    
Probe: MGI:1204988
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Pooled
Emaps: EMAPS:1866628
Stage: TS28
Assay Id: MGI:1204990
Age: postnatal week 6-8
Image: st96_352
Specimen Label: None
Detected: false
Specimen Num: 32
GXD Expression    
Probe: MGI:1204988
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3276428
Stage: TS28
Assay Id: MGI:1204990
Age: postnatal week 6-8
Image: st96_352
Specimen Label: None
Detected: true
Specimen Num: 33
GXD Expression    
Probe: MGI:1204988
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Pooled
Emaps: EMAPS:3519728
Stage: TS28
Assay Id: MGI:1204990
Age: postnatal week 6-8
Image: st96_352
Specimen Label: None
Detected: false
Specimen Num: 34
GXD Expression    
Probe: MGI:1204988
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Pooled
Emaps: EMAPS:3515128
Stage: TS28
Assay Id: MGI:1204990
Age: postnatal week 6-8
Image: st96_352
Specimen Label: None
Detected: false
Specimen Num: 35
GXD Expression    
Probe: MGI:1204988
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Pooled
Emaps: EMAPS:3528528
Stage: TS28
Assay Id: MGI:1204990
Age: postnatal week 6-8
Image: st96_352
Specimen Label: None
Detected: false
Specimen Num: 36
GXD Expression    
Probe: MGI:1204988
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Pooled
Emaps: EMAPS:3514028
Stage: TS28
Assay Id: MGI:1204990
Age: postnatal week 6-8
Image: st96_352
Specimen Label: None
Detected: false
Specimen Num: 37
GXD Expression    
Probe: MGI:1204988
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Pooled
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:1204990
Age: postnatal week 6-8
Image: st96_352
Specimen Label: None
Detected: false
Specimen Num: 38
GXD Expression    
Probe: MGI:1204988
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Female
Emaps: EMAPS:1775928
Stage: TS28
Assay Id: MGI:1204990
Age: postnatal week 6-8
Image: st96_352
Specimen Label: None
Detected: false
Specimen Num: 39
GXD Expression    
Probe: MGI:1204988
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Female
Emaps: EMAPS:1775928
Stage: TS28
Assay Id: MGI:1204990
Age: postnatal week 6-8
Image: st96_352
Specimen Label: None
Detected: false
Specimen Num: 40
GXD Expression    
Probe: MGI:1204988
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:1204990
Age: postnatal week 6-8
Image: st96_352
Specimen Label: None
Detected: true
Specimen Num: 41
GXD Expression    
Probe: MGI:1204988
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Male
Emaps: EMAPS:1929028
Stage: TS28
Assay Id: MGI:1204990
Age: postnatal week 6-8
Image: st96_352
Specimen Label: None
Detected: true
Specimen Num: 42
GXD Expression    
Probe: MGI:1204988
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Female
Emaps: EMAPS:1796228
Stage: TS28
Assay Id: MGI:1204990
Age: postnatal week 6-8
Image: st96_352
Specimen Label: None
Detected: false
Specimen Num: 43
GXD Expression    
Probe: MGI:1204988
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Female
Emaps: EMAPS:2992728
Stage: TS28
Assay Id: MGI:1204990
Age: postnatal week 6-8
Image: st96_352
Specimen Label: None
Detected: false
Specimen Num: 44