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Search results 1 to 100 out of 139 for Adamts13

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Hits by Pathway

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Hits by Strain

Type Details Score
Gene
11093 | ADAMTS13
Type: gene
Organism: human
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Gene
100485801 | adamts13
Type: gene
Organism: frog, western clawed
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Gene
473153 | ADAMTS13
Type: gene
Organism: chimpanzee
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Gene
532272 | ADAMTS13
Type: gene
Organism: cattle
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Gene
100630922 | ADAMTS13
Type: gene
Organism: dog, domestic
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Gene
417152 | ADAMTS13
Type: gene
Organism: chicken
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Gene
100320289 | adamts13
Type: gene
Organism: zebrafish
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Gene
722202 | ADAMTS13
Type: gene
Organism: macaque, rhesus
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Gene
102554393 | Adamts13
Type: gene
Organism: rat
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Protein Coding Gene
MGI:2685556 | Adamts13
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
21720563 | J:174381
First Author: Tati R
Year: 2011
Journal: PLoS One
Title: Phenotypic expression of ADAMTS13 in glomerular endothelial cells.
Volume: 6
Issue: 6
Pages: e21587
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Publication
22983446 | J:192128
First Author: Gandhi C
Year: 2012
Journal: Blood
Title: ADAMTS13 deficiency exacerbates VWF-dependent acute myocardial ischemia/reperfusion injury in mice.
Volume: 120
Issue: 26
Pages: 5224-30
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Publication
25813552 | J:230548
First Author: Geys L
Year: 2015
Journal: Biochim Biophys Acta
Title: ADAMTS13 deficiency in mice does not affect adipose tissue development.
Volume: 1850
Issue: 7
Pages: 1368-74
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Publication
23515928 | J:197915
First Author: Jin SY
Year: 2013
Journal: Blood
Title: AAV-mediated expression of an ADAMTS13 variant prevents shigatoxin-induced thrombotic thrombocytopenic purpura.
Volume: 121
Issue: 19
Pages: 3825-9, S1-3
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Publication
22915644 | J:192140
First Author: De Meyer SF
Year: 2012
Journal: Blood
Title: Protective anti-inflammatory effect of ADAMTS13 on myocardial ischemia/reperfusion injury in mice.
Volume: 120
Issue: 26
Pages: 5217-23
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Publication
25800050 | J:222270
First Author: Pickens B
Year: 2015
Journal: Blood
Title: Platelet-delivered ADAMTS13 inhibits arterial thrombosis and prevents thrombotic thrombocytopenic purpura in murine models.
Volume: 125
Issue: 21
Pages: 3326-34
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Publication
19141866 | J:146165
First Author: Laje P
Year: 2009
Journal: Blood
Title: Correction of murine ADAMTS13 deficiency by hematopoietic progenitor cell-mediated gene therapy.
Volume: 113
Issue: 10
Pages: 2172-80
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Publication
29976618 | J:267165
First Author: Cassis P
Year: 2018
Journal: Diabetes
Title: ADAMTS13 Deficiency Shortens the Life Span of Mice With Experimental Diabetes.
Volume: 67
Issue: 10
Pages: 2069-2083
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Publication
23878316 | J:205823
First Author: Tati R
Year: 2013
Journal: J Immunol
Title: Complement activation associated with ADAMTS13 deficiency in human and murine thrombotic microangiopathy.
Volume: 191
Issue: 5
Pages: 2184-93
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Publication
19541819 | J:152263
First Author: Raife TJ
Year: 2009
Journal: Blood
Title: Leukocyte proteases cleave von Willebrand factor at or near the ADAMTS13 cleavage site.
Volume: 114
Issue: 8
Pages: 1666-74
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Publication
39794345 | J:361425
First Author: Kwak H
Year: 2025
Journal: Sci Rep
Title: GC1126A, a novel ADAMTS13 mutein, evades autoantibodies in immune-mediated thrombotic thrombocytopenic purpura.
Volume: 15
Issue: 1
Pages: 1613
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Publication
15136581 | J:98410
First Author: Banno F
Year: 2004
Journal: J Biol Chem
Title: Identification of strain-specific variants of mouse Adamts13 gene encoding von Willebrand factor-cleaving protease.
Volume: 279
Issue: 29
Pages: 30896-903
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Publication
19109562 | J:148975
First Author: Banno F
Year: 2009
Journal: Blood
Title: The distal carboxyl-terminal domains of ADAMTS13 are required for regulation of in vivo thrombus formation.
Volume: 113
Issue: 21
Pages: 5323-9
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Publication
41009700 | J:388061
 
First Author: Baur C
Year: 2025
Journal: Int J Mol Sci
Title: An Expendable Player in Positive Vascular Remodeling? ADAMTS13 Deficiency Does Not Affect Arteriogenesis or Angiogenesis.
Volume: 26
Issue: 18
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Publication
22212812 | J:345736
First Author: Fujioka M
Year: 2012
Journal: Neurol Sci
Title: ADAMTS13 gene deletion enhances plasma high-mobility group box1 elevation and neuroinflammation in brain ischemia-reperfusion injury.
Volume: 33
Issue: 5
Pages: 1107-15
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Publication
19687510 | J:153541
First Author: Zhao BQ
Year: 2009
Journal: Blood
Title: von Willebrand factor-cleaving protease ADAMTS13 reduces ischemic brain injury in experimental stroke.
Volume: 114
Issue: 15
Pages: 3329-34
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Publication
22123843 | J:182469
First Author: Gandhi C
Year: 2012
Journal: Blood
Title: ADAMTS13 reduces vascular inflammation and the development of early atherosclerosis in mice.
Volume: 119
Issue: 10
Pages: 2385-91
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Publication
31409673 | J:280397
First Author: Zheng L
Year: 2019
Journal: Blood
Title: Synergistic effects of ADAMTS13 deficiency and complement activation in pathogenesis of thrombotic microangiopathy.
Volume: 134
Issue: 13
Pages: 1095-1105
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Publication
24261607 | J:280082
First Author: Gandhi C
Year: 2014
Journal: J Thromb Haemost
Title: ADAMTS13 modulates atherosclerotic plaque progression in mice via a VWF-dependent mechanism.
Volume: 12
Issue: 2
Pages: 255-60
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Publication
17426255 | J:145400
First Author: Zhou W
Year: 2007
Journal: Blood
Title: An IAP retrotransposon in the mouse ADAMTS13 gene creates ADAMTS13 variant proteins that are less effective in cleaving von Willebrand factor multimers.
Volume: 110
Issue: 3
Pages: 886-93
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Publication
28254814 | J:263674
First Author: Verhenne S
Year: 2017
Journal: Arterioscler Thromb Vasc Biol
Title: Long-Term Prevention of Congenital Thrombotic Thrombocytopenic Purpura in ADAMTS13 Knockout Mice by Sleeping Beauty Transposon-Mediated Gene Therapy.
Volume: 37
Issue: 5
Pages: 836-844
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Publication
16368888 | J:125786
First Author: Banno F
Year: 2006
Journal: Blood
Title: Complete deficiency in ADAMTS13 is prothrombotic, but it alone is not sufficient to cause thrombotic thrombocytopenic purpura.
Volume: 107
Issue: 8
Pages: 3161-6
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Publication
25442981 | J:345773
First Author: De Cock E
Year: 2015
Journal: J Thromb Haemost
Title: The novel ADAMTS13-p.D187H mutation impairs ADAMTS13 activity and secretion and contributes to thrombotic thrombocytopenic purpura in mice.
Volume: 13
Issue: 2
Pages: 283-92
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Publication
27479501 | J:254416
First Author: Deforche L
Year: 2016
Journal: PLoS One
Title: Generation of Anti-Murine ADAMTS13 Antibodies and Their Application in a Mouse Model for Acquired Thrombotic Thrombocytopenic Purpura.
Volume: 11
Issue: 8
Pages: e0160388
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Publication
28495930 | J:269183
First Author: Dhanesha N
Year: 2017
Journal: Arterioscler Thromb Vasc Biol
Title: ADAMTS13 Retards Progression of Diabetic Nephropathy by Inhibiting Intrarenal Thrombosis in Mice.
Volume: 37
Issue: 7
Pages: 1332-1338
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Publication
18083848 | J:133469
First Author: Chauhan AK
Year: 2008
Journal: Blood
Title: The combined roles of ADAMTS13 and VWF in murine models of TTP, endotoxemia, and thrombosis.
Volume: 111
Issue: 7
Pages: 3452-7
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Publication
22652598 | J:201491
First Author: Jin SY
Year: 2012
Journal: Arterioscler Thromb Vasc Biol
Title: Genetic ablation of Adamts13 gene dramatically accelerates the formation of early atherosclerosis in a murine model.
Volume: 32
Issue: 8
Pages: 1817-23
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Publication
23144461 | J:345734
First Author: Hershko K
Year: 2012
Journal: J Biol Chem
Title: Cyclosporin A impairs the secretion and activity of ADAMTS13 (a disintegrin and metalloprotease with thrombospondin type 1 repeat).
Volume: 287
Issue: 53
Pages: 44361-71
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Publication
30354235 | J:340193
First Author: Abdelgawwad MS
Year: 2018
Journal: Arterioscler Thromb Vasc Biol
Title: Transfusion of Platelets Loaded With Recombinant ADAMTS13 (A Disintegrin and Metalloprotease With Thrombospondin Type 1 Repeats-13) Is Efficacious for Inhibiting Arterial Thrombosis Associated With Thrombotic Thrombocytopenic Purpura.
Volume: 38
Issue: 11
Pages: 2731-2743
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Publication
24357063 | J:318242
First Author: Bao J
Year: 2014
Journal: Arterioscler Thromb Vasc Biol
Title: Carboxyl terminus of ADAMTS13 directly inhibits platelet aggregation and ultra large von Willebrand factor string formation under flow in a free-thiol-dependent manner.
Volume: 34
Issue: 2
Pages: 397-407
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Publication
16200209 | J:101752
First Author: Motto DG
Year: 2005
Journal: J Clin Invest
Title: Shigatoxin triggers thrombotic thrombocytopenic purpura in genetically susceptible ADAMTS13-deficient mice.
Volume: 115
Issue: 10
Pages: 2752-61
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Publication
22529289 | J:188653
First Author: Schiviz A
Year: 2012
Journal: Blood
Title: A new mouse model mimicking thrombotic thrombocytopenic purpura: correction of symptoms by recombinant human ADAMTS13.
Volume: 119
Issue: 25
Pages: 6128-35
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Publication
21799176 | J:191846
First Author: Xiao J
Year: 2011
Journal: Arterioscler Thromb Vasc Biol
Title: Essential domains of a disintegrin and metalloprotease with thrombospondin type 1 repeats-13 metalloprotease required for modulation of arterial thrombosis.
Volume: 31
Issue: 10
Pages: 2261-9
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Publication
31340669 | J:306859
First Author: Adili R
Year: 2019
Journal: Arterioscler Thromb Vasc Biol
Title: Formation and Resolution of Pial Microvascular Thrombosis in a Mouse Model of Thrombotic Thrombocytopenic Purpura.
Volume: 39
Issue: 9
Pages: 1817-1830
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Publication
16533881 | J:123759
First Author: Chauhan AK
Year: 2006
Journal: J Exp Med
Title: Systemic antithrombotic effects of ADAMTS13.
Volume: 203
Issue: 3
Pages: 767-76
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Publication
24713928 | J:213135
First Author: Morioka Y
Year: 2014
Journal: Blood
Title: Expression of a structurally constrained von Willebrand factor variant triggers acute thrombotic thrombocytopenic purpura in mice.
Volume: 123
Issue: 21
Pages: 3344-53
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Publication
27444201 | J:247157
First Author: Dhanesha N
Year: 2016
Journal: Arterioscler Thromb Vasc Biol
Title: Endothelial Cell-Derived von Willebrand Factor Is the Major Determinant That Mediates von Willebrand Factor-Dependent Acute Ischemic Stroke by Promoting Postischemic Thrombo-Inflammation.
Volume: 36
Issue: 9
Pages: 1829-37
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Publication
21346256 | J:172829
First Author: Pruss CM
Year: 2011
Journal: Blood
Title: Pathologic mechanisms of type 1 VWD mutations R1205H and Y1584C through in vitro and in vivo mouse models.
Volume: 117
Issue: 16
Pages: 4358-66
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Publication
18695007 | J:142125
First Author: Chauhan AK
Year: 2008
Journal: J Exp Med
Title: ADAMTS13: a new link between thrombosis and inflammation.
Volume: 205
Issue: 9
Pages: 2065-74
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Publication
20200350 | J:161564
First Author: Rayes J
Year: 2010
Journal: Blood
Title: Mutation and ADAMTS13-dependent modulation of disease severity in a mouse model for von Willebrand disease type 2B.
Volume: 115
Issue: 23
Pages: 4870-7
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Publication
25977583 | J:222931
First Author: Bauer AT
Year: 2015
Journal: Blood
Title: von Willebrand factor fibers promote cancer-associated platelet aggregation in malignant melanoma of mice and humans.
Volume: 125
Issue: 20
Pages: 3153-63
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Publication
26929275 | J:233014
First Author: Denorme F
Year: 2016
Journal: Blood
Title: ADAMTS13-mediated thrombolysis of t-PA-resistant occlusions in ischemic stroke in mice.
Volume: 127
Issue: 19
Pages: 2337-45
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Publication
31099973 | J:295783
First Author: Kraisin S
Year: 2019
Journal: J Thromb Haemost
Title: von Willebrand factor in experimental malaria-associated acute respiratory distress syndrome.
Volume: 17
Issue: 8
Pages: 1372-1383
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Publication
27602496 | J:310954
First Author: Goertz L
Year: 2016
Journal: Oncotarget
Title: Heparins that block VEGF-A-mediated von Willebrand factor fiber generation are potent inhibitors of hematogenous but not lymphatic metastasis.
Volume: 7
Issue: 42
Pages: 68527-68545
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Protein Coding Gene
MGP_CAROLIEiJ_G0023333 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0025505 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0025482 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0025452 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0025478 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0025239 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2685556 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0025922 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0024702 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0025217 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0025350 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0025312 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0025436 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0025343 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0025981 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0024450 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0024771 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0024790 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0024250 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
20644116 | J:166480
First Author: Huang J
Year: 2010
Journal: Blood
Title: Shiga toxin B subunits induce VWF secretion by human endothelial cells and thrombotic microangiopathy in ADAMTS13-deficient mice.
Volume: 116
Issue: 18
Pages: 3653-9
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Publication
28011677 | J:240106
First Author: Tersteeg C
Year: 2017
Journal: Blood
Title: N-acetylcysteine in preclinical mouse and baboon models of thrombotic thrombocytopenic purpura.
Volume: 129
Issue: 8
Pages: 1030-1038
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GXD Expression
GXD Expression
     
Probe: MGI:5002547
Assay Type: RT-PCR
Annotation Date: 2011-06-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603911
Stage: TS11
Assay Id: MGI:5002863
Age: embryonic day 7.5
Specimen Label: E7.5
Detected: false
Specimen Num: 1
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Publication
25835743 | J:219914
First Author: Concepcion D
Year: 2015
Journal: PLoS Genet
Title: Nxf1 natural variant E610G is a semi-dominant suppressor of IAP-induced RNA processing defects.
Volume: 11
Issue: 4
Pages: e1005123
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Publication
22915646 | J:191809
First Author: Navarrete AM
Year: 2012
Journal: Blood
Title: A murine model to characterize the antithrombotic effect of molecules targeting human von Willebrand factor.
Volume: 120
Issue: 13
Pages: 2723-32
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Publication
16204318 | J:127571
First Author: Bonnefoy A
Year: 2006
Journal: Blood
Title: Thrombospondin-1 controls vascular platelet recruitment and thrombus adherence in mice by protecting (sub)endothelial VWF from cleavage by ADAMTS13.
Volume: 107
Issue: 3
Pages: 955-64
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Publication
21266777 | J:171826
First Author: Chen J
Year: 2011
Journal: J Clin Invest
Title: N-acetylcysteine reduces the size and activity of von Willebrand factor in human plasma and mice.
Volume: 121
Issue: 2
Pages: 593-603
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Publication
29941674 | J:265980
First Author: Wu Y
Year: 2018
Journal: Blood
Title: von Willebrand factor enhances microvesicle-induced vascular leakage and coagulopathy in mice with traumatic brain injury.
Volume: 132
Issue: 10
Pages: 1075-1084
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Publication
25244095 | J:217625
First Author: Zhu Q
Year: 2014
Journal: J Clin Invest
Title: Syntaxin-binding protein STXBP5 inhibits endothelial exocytosis and promotes platelet secretion.
Volume: 124
Issue: 10
Pages: 4503-16
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Publication
25934767 | J:320478
First Author: Onclinx C
Year: 2015
Journal: Haematologica
Title: Deficiency in mouse hyaluronidase 2: a new mechanism of chronic thrombotic microangiopathy.
Volume: 100
Issue: 8
Pages: 1023-30
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Publication
32967458 | J:318568
First Author: Michels A
Year: 2020
Journal: Arterioscler Thromb Vasc Biol
Title: von Willebrand Factor Is a Critical Mediator of Deep Vein Thrombosis in a Mouse Model of Diet-Induced Obesity.
Volume: 40
Issue: 12
Pages: 2860-2874
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Publication
29348121 | J:277976
First Author: Doddapattar P
Year: 2018
Journal: Arterioscler Thromb Vasc Biol
Title: Endothelial Cell-Derived Von Willebrand Factor, But Not Platelet-Derived, Promotes Atherosclerosis in Apolipoprotein E-Deficient Mice.
Volume: 38
Issue: 3
Pages: 520-528
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Publication
17509843 | J:124013
First Author: Koo BH
Year: 2007
Journal: Matrix Biol
Title: ADAMTS-like 2 (ADAMTSL2) is a secreted glycoprotein that is widely expressed during mouse embryogenesis and is regulated during skeletal myogenesis.
Volume: 26
Issue: 6
Pages: 431-41
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Publication
22232208 | J:184379
First Author: Petruzziello-Pellegrini TN
Year: 2012
Journal: J Clin Invest
Title: The CXCR4/CXCR7/SDF-1 pathway contributes to the pathogenesis of Shiga toxin-associated hemolytic uremic syndrome in humans and mice.
Volume: 122
Issue: 2
Pages: 759-76
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Publication
25770910 | J:224408
 
First Author: Dubail J
Year: 2015
Journal: Matrix Biol
Title: Insights on ADAMTS proteases and ADAMTS-like proteins from mammalian genetics.
Volume: 44-46
Pages: 24-37
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Publication
39879696 | J:361964
 
First Author: Wang M
Year: 2025
Journal: Biochem Biophys Res Commun
Title: The secreted protease ADAMTS18 links early isoform transformation and maturation of glomerular basement membrane macromolecules to the integrity of the glomerular filtration barrier.
Volume: 750
Pages: 151386
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Publication
20637190 | J:165751
First Author: Du J
Year: 2010
Journal: Dev Biol
Title: O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.
Volume: 346
Issue: 1
Pages: 25-38
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Publication
- | J:66661
       
First Author: National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health
Year: 2001
Title: GenBank Record Derived Information
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
27626380 | J:236599
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
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Publication
- | J:84900
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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