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Search results 1 to 83 out of 83 for Adamtsl1

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Type Details Score
Gene
Type: gene
Organism: human
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Gene
Type: gene
Organism: frog, western clawed
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Gene
Type: gene
Organism: rat
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Gene
Type: gene
Organism: chimpanzee
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Gene
Type: gene
Organism: dog, domestic
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Gene
Type: gene
Organism: chicken
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Gene
Type: gene
Organism: macaque, rhesus
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Gene
Type: gene
Organism: cattle
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression      
Probe: MGI:5002555
Assay Type: RT-PCR
Annotation Date: 2011-06-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603911
Stage: TS11
Assay Id: MGI:5002871
Age: embryonic day 7.5
Specimen Label: E7.5
Detected: false
Specimen Num: 1
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Publication
First Author: Hall NG
Year: 2003
Journal: Matrix Biol
Title: ADAMTSL-3/punctin-2, a novel glycoprotein in extracellular matrix related to the ADAMTS family of metalloproteases.
Volume: 22
Issue: 6
Pages: 501-10
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Publication
First Author: Du J
Year: 2010
Journal: Dev Biol
Title: O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.
Volume: 346
Issue: 1
Pages: 25-38
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Publication  
First Author: Naba A
Year: 2017
Journal: Sci Rep
Title: Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.
Volume: 7
Pages: 40495
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Publication
First Author: Naba A
Year: 2012
Journal: Mol Cell Proteomics
Title: The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.
Volume: 11
Issue: 4
Pages: M111.014647
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Publication
First Author: Tang T
Year: 2010
Journal: Nat Biotechnol
Title: A mouse knockout library for secreted and transmembrane proteins.
Volume: 28
Issue: 7
Pages: 749-55
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Publication      
First Author: Lexicon Genetics, Inc
Year: 2011
Journal: Database Download
Title: MGI download of Lexicon knockout data
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Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: FANTOM2 Data Curation in Mouse Genome Informatics
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Publication
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
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Publication      
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication        
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication      
First Author: Mouse Genome Informatics and Ensembl Genome Database Project
Year: 2026
Journal: Database Release
Title: MGI Strain Genome Feature and Gene Model Load from Ensembl.
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Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Allele
Name: ADAMTS-like 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Publication
First Author: Yim AKY
Year: 2022
Journal: Nat Neurosci
Title: Disentangling glial diversity in peripheral nerves at single-nuclei resolution.
Volume: 25
Issue: 2
Pages: 238-251
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Protein
Organism: Mus musculus/domesticus
Length: 429  
Fragment?: false
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Protein
Organism: Mus musculus/domesticus
Length: 429  
Fragment?: false
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Protein
Organism: Mus musculus/domesticus
Length: 170  
Fragment?: true
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Protein
Organism: Mus musculus/domesticus
Length: 209  
Fragment?: true
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Protein
Organism: Mus musculus/domesticus
Length: 168  
Fragment?: false
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Protein
Organism: Mus musculus/domesticus
Length: 429  
Fragment?: false
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Protein
Organism: Mus musculus/domesticus
Length: 164  
Fragment?: true
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Publication
First Author: Chen CI
Year: 2012
Journal: EMBO J
Title: Structure of human POFUT2: insights into thrombospondin type 1 repeat fold and O-fucosylation.
Volume: 31
Issue: 14
Pages: 3183-97
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Publication  
First Author: Berardinelli SJ
Year: 2020
Journal: Methods Mol Biol
Title: Analyzing the Effects of O-Fucosylation on Secretion of ADAMTS Proteins Using Cell-Based Assays.
Volume: 2043
Pages: 25-43
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Publication
First Author: Ricketts LM
Year: 2007
Journal: J Biol Chem
Title: O-fucosylation is required for ADAMTS13 secretion.
Volume: 282
Issue: 23
Pages: 17014-23
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Publication
First Author: Voxeur A
Year: 2012
Journal: PLoS One
Title: Identification of putative rhamnogalacturonan-II specific glycosyltransferases in Arabidopsis using a combination of bioinformatics approaches.
Volume: 7
Issue: 12
Pages: e51129
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Publication
First Author: Wang LW
Year: 2007
Journal: J Biol Chem
Title: O-fucosylation of thrombospondin type 1 repeats in ADAMTS-like-1/punctin-1 regulates secretion: implications for the ADAMTS superfamily.
Volume: 282
Issue: 23
Pages: 17024-31
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Publication
First Author: Nofiani R
Year: 2018
Journal: Nat Commun
Title: Strobilurin biosynthesis in Basidiomycete fungi.
Volume: 9
Issue: 1
Pages: 3940
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Protein Domain
Type: Family
Description: This entry represents protein O-fucosyltransferase 2 (POFUT2), a GDP-fucose protein O-fucosyltransferase involved in one of the two pathways responsible for protein O-linked fucosylation, a post-translational modification that regulates various biological functions in cysteine-knotted proteins []. This pathway targets proteins bearing Thrombospondin type-1 (TSP1) repeats (TSRs) in the endoplasmic reticulum.POFUT2 catalyses the attachment of fucose through an O-glycosidic linkage to a conserved serine or threonine residue within the consensus sequence C1-X-X-S/T-C2 of TSRs, where C1 and C2 are the first and second cysteines of the repeat, respectively []. It O-fucosylates members of several protein families, including the ADAMTS, thrombospondin (TSP) and spondin families [].POFUT2 is required for the proper secretion of ADAMTS (a disintegrin and metalloproteinase with thrombospondin type 1 repeats) family members such as ADAMTSL1 and ADAMTS13 [, , ]. Additionally, O-fucosylation of TSRs is required for restricting epithelial to mesenchymal transition (EMT), maintaining correct patterning of mesoderm and localisation of the definitive endoderm.This entry also includes strobilurin A biosynthesis cluster protein Stl1, a component of the gene cluster mediating the biosynthesis of strobilurin A, an antifungal polyketide characterised by a beta-methoxyacrylate toxophore that targets complex III of the mitochondrial electron transport chain [].Strobilurin A biosynthesis is initiated by the construction of benzoyl CoA from phenylalanine through sequential reactions involving a phenylalanine ammonia-lyase (Str11), an oxygenase (Str8), and a retro-Claisen reaction to yield benzoic acid, which is then activated to benzoyl CoA by the CoA ligase Str10. Benzoyl CoA serves as the starter unit for the highly reducing polyketide synthase StPKS1, which produces the intermediate prestrobilutin A. The FAD-dependent oxygenase Str9 then catalyses the key oxidative rearrangement that generates the beta-methoxyacrylate toxophore, likely through epoxidation of the 2,3 olefin of prestrobilutin A followed by Meinwald rearrangement. Final methylations by Str2 and Str3 complete the synthesis of strobilurin A, while the dehydrogenases Stl2 and Str4 are involved in a shunt pathway leading to the production of bolineol [].This entry also includes some O-fucosyltransferase (5, 14, 36) from plants. These proteins are involved in glycan metabolism [].
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