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Search results 1 to 100 out of 126 for Akap13

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Hits by Pathway

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Hits by Category

Type Details Score
Gene
11214 | AKAP13
Type: gene
Organism: human
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Gene
327519 | akap13
Type: gene
Organism: zebrafish
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Gene
698172 | AKAP13
Type: gene
Organism: macaque, rhesus
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Gene
100485001 | akap13
Type: gene
Organism: frog, western clawed
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Gene
293024 | Akap13
Type: gene
Organism: rat
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Gene
479032 | AKAP13
Type: gene
Organism: dog, domestic
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Gene
743772 | AKAP13
Type: gene
Organism: chimpanzee
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Gene
504288 | AKAP13
Type: gene
Organism: cattle
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Gene
415502 | AKAP13
Type: gene
Organism: chicken
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Protein Domain
IPR028852 | AKAP13
Type: Family
Description: A-kinase anchor protein 13 (AKAP13, also known as AKAP-Lbc) belongs to the AKAP family, which contains functionally related proteins involved in the targeting of the PKA holoenzyme towards specific physiological substrates []. AKAP13 anchors cAMP-dependent protein kinase (PKA) and acts as a guanine nucleotide exchange factor (GEF) that activates the GTPase RhoA []. The Rho-GEF activity of AKAP13 can be inhibited by protein 14-3-3 when it adopts an oligomeric conformation []. AKAP13 has been shown to be essential for cardiac development in mice []. It also plays a role in osteogenesis [].
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Protein Coding Gene
MGI:2676556 | Akap13
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
25892096 | J:231357
First Author: Koide H
Year: 2015
Journal: J Bone Miner Res
Title: Mice Deficient in AKAP13 (BRX) Are Osteoporotic and Have Impaired Osteogenesis.
Volume: 30
Issue: 10
Pages: 1887-95
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Publication
20139090 | J:181087
First Author: Mayers CM
Year: 2010
Journal: J Biol Chem
Title: The Rho guanine nucleotide exchange factor AKAP13 (BRX) is essential for cardiac development in mice.
Volume: 285
Issue: 16
Pages: 12344-54
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Gene
123466214 | AKAP13-AS1
Type: gene
Organism: human
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Publication
24161911 | J:238039
 
First Author: Taglieri DM
Year: 2014
Journal: J Mol Cell Cardiol
Title: The C-terminus of the long AKAP13 isoform (AKAP-Lbc) is critical for development of compensatory cardiac hypertrophy.
Volume: 66
Pages: 27-40
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Publication
23658642 | J:231257
First Author: Spindler MJ
Year: 2013
Journal: PLoS One
Title: AKAP13 Rho-GEF and PKD-binding domain deficient mice develop normally but have an abnormal response to β-adrenergic-induced cardiac hypertrophy.
Volume: 8
Issue: 4
Pages: e62705
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Protein
Q9D9W9
Organism: Mus musculus/domesticus
Length: 228  
Fragment?: false
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Protein
Q924X9
Organism: Mus musculus/domesticus
Length: 934  
Fragment?: true
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Protein
A0A668KL88
Organism: Mus musculus/domesticus
Length: 121  
Fragment?: true
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Protein
A0A140LID7
Organism: Mus musculus/domesticus
Length: 569  
Fragment?: true
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Protein
Q3T998
Organism: Mus musculus/domesticus
Length: 186  
Fragment?: true
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Protein
A0A140LHQ3
Organism: Mus musculus/domesticus
Length: 423  
Fragment?: true
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Protein
A0A140LIX0
Organism: Mus musculus/domesticus
Length: 870  
Fragment?: true
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Protein
Q3TR80
Organism: Mus musculus/domesticus
Length: 238  
Fragment?: false
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Publication
11546812 | -
First Author: Diviani D
Year: 2001
Journal: J Biol Chem
Title: AKAP-Lbc anchors protein kinase A and nucleates Galpha 12-selective Rho-mediated stress fiber formation.
Volume: 276
Issue: 47
Pages: 44247-57
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Publication
16460837 | -
First Author: Diviani D
Year: 2006
Journal: Eur J Cell Biol
Title: AKAP-Lbc: a molecular scaffold for the integration of cyclic AMP and Rho transduction pathways.
Volume: 85
Issue: 7
Pages: 603-10
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Protein
Q3TA34
Organism: Mus musculus/domesticus
Length: 345  
Fragment?: true
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Protein
Q3TZA8
Organism: Mus musculus/domesticus
Length: 360  
Fragment?: true
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Protein
Q8BYV7
Organism: Mus musculus/domesticus
Length: 108  
Fragment?: false
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Protein
E9Q394
Organism: Mus musculus/domesticus
Length: 2776  
Fragment?: false
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Protein
A0A140LJJ5
Organism: Mus musculus/domesticus
Length: 2794  
Fragment?: false
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Protein
Q3UZK5
Organism: Mus musculus/domesticus
Length: 607  
Fragment?: true
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Protein
A0A140LHG3
Organism: Mus musculus/domesticus
Length: 607  
Fragment?: true
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Publication
26192751 | J:244762
First Author: Johnson KR
Year: 2015
Journal: PLoS One
Title: Genome-Wide Gene Expression Analysis Shows AKAP13-Mediated PKD1 Signaling Regulates the Transcriptional Response to Cardiac Hypertrophy.
Volume: 10
Issue: 7
Pages: e0132474
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Protein Coding Gene
MGP_CAROLIEiJ_G0029865 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0032374 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0032353 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0032289 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0032365 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0032078 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2676556 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0032857 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0031406 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0032044 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0032199 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0032154 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0032280 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0032191 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0032875 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0031126 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0031524 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0013087 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0030967 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
1731775 | J:11574
First Author: Tsuchiya T
Year: 1992
Journal: Biochem Biophys Res Commun
Title: In vitro reconstitution of an erythropoietin gene transcription system using its 5'-flanking sequence and a nuclear extract from anemic kidney.
Volume: 182
Issue: 1
Pages: 137-43
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GXD Expression
GXD Expression
   
Probe: MGI:5816371
Assay Type: Northern blot
Annotation Date: 2017-01-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:5816372
Age: postnatal
Image: 1
Specimen Label: Heart
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5816371
Assay Type: Northern blot
Annotation Date: 2017-01-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5816372
Age: postnatal
Image: 1
Specimen Label: Brain
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5816371
Assay Type: Northern blot
Annotation Date: 2017-01-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:5816372
Age: postnatal
Image: 1
Specimen Label: Spleen
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:5816371
Assay Type: Northern blot
Annotation Date: 2017-01-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:5816372
Age: postnatal
Image: 1
Specimen Label: Lung
Detected: false
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:5816371
Assay Type: Northern blot
Annotation Date: 2017-01-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:5816372
Age: postnatal
Image: 1
Specimen Label: Liver
Detected: false
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:5816285
Assay Type: RT-PCR
Annotation Date: 2017-01-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:5816468
Age: embryonic day 9.0-9.5
Image: 1
Specimen Label: 1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5816285
Assay Type: RT-PCR
Annotation Date: 2017-01-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:5816468
Age: embryonic day 9.0-9.5
Image: 1
Specimen Label: 3
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:5816285
Assay Type: RT-PCR
Annotation Date: 2017-01-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:5816468
Age: embryonic day 9.0-9.5
Image: 1
Specimen Label: 5
Detected: false
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:5816285
Assay Type: RT-PCR
Annotation Date: 2017-01-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:5816468
Age: embryonic day 9.0-9.5
Image: 1
Specimen Label: 7
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
   
Probe: MGI:5816287
Assay Type: RT-PCR
Annotation Date: 2017-01-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610514
Stage: TS14
Assay Id: MGI:5816485
Age: embryonic day 9.0
Image: 6
Specimen Label: WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5816287
Assay Type: RT-PCR
Annotation Date: 2017-01-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610514
Stage: TS14
Assay Id: MGI:5816485
Age: embryonic day 9.0
Image: 6
Specimen Label: +/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5816287
Assay Type: RT-PCR
Annotation Date: 2017-01-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610514
Stage: TS14
Assay Id: MGI:5816485
Age: embryonic day 9.0
Image: 6
Specimen Label: -/-
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:5816294
Assay Type: Immunohistochemistry
Annotation Date: 2017-01-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1611815
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:5816470
Age: embryonic day 9.0-9.5
Image: 2E
Specimen Label: 2E
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5816294
Assay Type: Immunohistochemistry
Annotation Date: 2017-01-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640515
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:5816470
Age: embryonic day 9.0-9.5
Image: 2E
Specimen Label: 2E
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5816294
Assay Type: Immunohistochemistry
Annotation Date: 2017-01-03
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3268815
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:5816470
Age: embryonic day 9.0-9.5
Image: 2E
Specimen Label: 2E
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5816294
Assay Type: Immunohistochemistry
Annotation Date: 2017-01-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3268815
Stage: TS15
Assay Id: MGI:5816470
Age: embryonic day 9.0-9.5
Image: 2F
Specimen Label: 2F
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:5816294
Assay Type: Immunohistochemistry
Annotation Date: 2017-01-03
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3268828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5816470
Age: postnatal adult
Image: S2A
Specimen Label: S2A
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
Probe: MGI:5816294
Assay Type: Immunohistochemistry
Annotation Date: 2017-01-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3268828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5816470
Age: postnatal adult
Image: S2C
Note: Expression is localized to sarcomeres.
Specimen Label: S2C
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
Probe: MGI:5816294
Assay Type: Immunohistochemistry
Annotation Date: 2017-01-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3268816
Pattern: Not Specified
Stage: TS16
Assay Id: MGI:5816487
Age: embryonic day 9.5-10.0
Image: S2E
Note: Expression is at the Z-discs of sarcomeres.
Specimen Label: S2E
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5816294
Assay Type: Immunohistochemistry
Annotation Date: 2017-01-03
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1610517
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:5816470
Age: embryonic day 10.0-10.5
Image: 2G
Specimen Label: 2G
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:5816294
Assay Type: Immunohistochemistry
Annotation Date: 2017-01-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610517
Stage: TS17
Assay Id: MGI:5816470
Age: embryonic day 10.0-10.5
Image: 2H
Specimen Label: 2H
Detected: false
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:5816294
Assay Type: Immunohistochemistry
Annotation Date: 2017-01-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1664015
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:5816470
Age: embryonic day 9.0-9.5
Image: 2E
Specimen Label: 2E
Detected: true
Specimen Num: 1
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Publication
16469733 | J:111574
First Author: Kino T
Year: 2006
Journal: J Biol Chem
Title: Rho family Guanine nucleotide exchange factor Brx couples extracellular signals to the glucocorticoid signaling system.
Volume: 281
Issue: 14
Pages: 9118-26
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Publication
19211510 | J:181088
First Author: Kino T
Year: 2009
Journal: Sci Signal
Title: Brx mediates the response of lymphocytes to osmotic stress through the activation of NFAT5.
Volume: 2
Issue: 57
Pages: ra5
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Publication
23716597 | J:204574
First Author: Pérez López I
Year: 2013
Journal: Mol Cell Biol
Title: A-kinase anchoring protein Lbc coordinates a p38 activating signaling complex controlling compensatory cardiac hypertrophy.
Volume: 33
Issue: 15
Pages: 2903-17
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Publication
29298866 | J:254437
 
First Author: Serr I
Year: 2018
Journal: Sci Transl Med
Title: A miRNA181a/NFAT5 axis links impaired T cell tolerance induction with autoimmune type 1 diabetes.
Volume: 10
Issue: 422
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Publication
31541165 | J:284228
First Author: Ikegami K
Year: 2019
Journal: Sci Rep
Title: Effect of expression alteration in flanking genes on phenotypes of St8sia2-deficient mice.
Volume: 9
Issue: 1
Pages: 13634
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Publication
26921296 | J:244712
First Author: Navarro N
Year: 2016
Journal: G3 (Bethesda)
Title: Does 3D Phenotyping Yield Substantial Insights in the Genetics of the Mouse Mandible Shape?
Volume: 6
Issue: 5
Pages: 1153-63
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
15741177 | J:126097
First Author: Cobellis G
Year: 2005
Journal: Nucleic Acids Res
Title: Tagging genes with cassette-exchange sites.
Volume: 33
Issue: 4
Pages: e44
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Publication
- | J:66660
       
First Author: Mouse Genome Database and National Center for Biotechnology Information Editorial Staff Collaboration
Year: 2001
Title: LocusLink Collaboration
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Publication
- | J:81858
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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