| Type |
Details |
Score |
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, western clawed |
|
•
•
•
•
•
|
| Gene |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
dog, domestic |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chimpanzee |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
cattle |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Krieg P |
| Year: |
2013 |
| Journal: |
J Invest Dermatol |
| Title: |
Aloxe3 knockout mice reveal a function of epidermal lipoxygenase-3 as hepoxilin synthase and its pivotal role in barrier formation. |
| Volume: |
133 |
| Issue: |
1 |
| Pages: |
172-80 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kinzig A |
| Year: |
1999 |
| Journal: |
Genomics |
| Title: |
cDNA cloning, genomic structure, and chromosomal localization of a novel murine epidermis-type lipoxygenase. |
| Volume: |
58 |
| Issue: |
2 |
| Pages: |
158-64 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yu Z |
| Year: |
2006 |
| Journal: |
Arch Biochem Biophys |
| Title: |
Human and mouse eLOX3 have distinct substrate specificities: implications for their linkage with lipoxygenases in skin. |
| Volume: |
455 |
| Issue: |
2 |
| Pages: |
188-96 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hallenborg P |
| Year: |
2010 |
| Journal: |
Mol Cell Biol |
| Title: |
Epidermis-type lipoxygenase 3 regulates adipocyte differentiation and peroxisome proliferator-activated receptor gamma activity. |
| Volume: |
30 |
| Issue: |
16 |
| Pages: |
4077-91 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Krieg P |
| Year: |
2014 |
| Journal: |
Biochim Biophys Acta |
| Title: |
The role of lipoxygenases in epidermis. |
| Volume: |
1841 |
| Issue: |
3 |
| Pages: |
390-400 |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, western clawed |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, African clawed |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, African clawed |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, African clawed |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus caroli |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus pahari |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus spretus |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6256782 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2018-12-02 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1603910 |
|
| Stage: |
TS10 |
| Assay Id: |
MGI:6258646 |
| Age: |
embryonic day 6.0-7.0 |
|
|
| Specimen Label: |
U46A Gpx4-/-;Alox15-/- |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6256782 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2018-12-02 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1603910 |
|
| Stage: |
TS10 |
| Assay Id: |
MGI:6258646 |
| Age: |
embryonic day 6.0-7.0 |
|
|
| Specimen Label: |
U46A Gpx4-/+;Alox15-/- |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6256782 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2018-12-02 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1603910 |
|
| Stage: |
TS10 |
| Assay Id: |
MGI:6258646 |
| Age: |
embryonic day 6.0-7.0 |
|
|
| Specimen Label: |
U46A Gpx4+/+;Alox15-/- |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6423356 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2020-05-19 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1752826 |
|
| Stage: |
TS26 |
| Assay Id: |
MGI:6423368 |
| Age: |
embryonic day 18.5 |
|
|
| Specimen Label: |
WT |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6423356 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2020-05-19 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1752826 |
|
| Stage: |
TS26 |
| Assay Id: |
MGI:6423368 |
| Age: |
embryonic day 18.5 |
|
|
| Specimen Label: |
KO |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7461598 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2023-04-13 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1752526 |
|
| Stage: |
TS26 |
| Assay Id: |
MGI:7461620 |
| Age: |
embryonic day 18.5 |
|
|
| Specimen Label: |
WT |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7461598 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2023-04-13 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1752526 |
|
| Stage: |
TS26 |
| Assay Id: |
MGI:7461620 |
| Age: |
embryonic day 18.5 |
|
|
| Specimen Label: |
Pnpla1 tm1a |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7543480 |
| Assay Type: |
Western blot |
| Annotation Date: |
2023-10-26 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1752826 |
|
| Stage: |
TS26 |
| Assay Id: |
MGI:7543545 |
| Age: |
embryonic day 18.5 |
|
|
| Specimen Label: |
WT |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7543480 |
| Assay Type: |
Western blot |
| Annotation Date: |
2023-10-26 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1752826 |
|
| Stage: |
TS26 |
| Assay Id: |
MGI:7543545 |
| Age: |
embryonic day 18.5 |
|
|
| Specimen Label: |
Ctip2-/- |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Epp N |
| Year: |
2007 |
| Journal: |
J Cell Biol |
| Title: |
12R-lipoxygenase deficiency disrupts epidermal barrier function. |
| Volume: |
177 |
| Issue: |
1 |
| Pages: |
173-82 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bessho Y |
| Year: |
2001 |
| Journal: |
Genes Cells |
| Title: |
Hes7: a bHLH-type repressor gene regulated by Notch and expressed in the presomitic mesoderm. |
| Volume: |
6 |
| Issue: |
2 |
| Pages: |
175-85 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Brütsch SH |
| Year: |
2015 |
| Journal: |
Antioxid Redox Signal |
| Title: |
Expression of inactive glutathione peroxidase 4 leads to embryonic lethality, and inactivation of the Alox15 gene does not rescue such knock-in mice. |
| Volume: |
22 |
| Issue: |
4 |
| Pages: |
281-93 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Miyamoto M |
| Year: |
2020 |
| Journal: |
J Invest Dermatol |
| Title: |
Severe Skin Permeability Barrier Dysfunction in Knockout Mice Deficient in a Fatty Acid ω-Hydroxylase Crucial to Acylceramide Production. |
| Volume: |
140 |
| Issue: |
2 |
| Pages: |
319-326.e4 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tzeng J |
| Year: |
2015 |
| Journal: |
PLoS One |
| Title: |
An Ideal PPAR Response Element Bound to and Activated by PPARα. |
| Volume: |
10 |
| Issue: |
8 |
| Pages: |
e0134996 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Pichery M |
| Year: |
2017 |
| Journal: |
Hum Mol Genet |
| Title: |
PNPLA1 defects in patients with autosomal recessive congenital ichthyosis and KO mice sustain PNPLA1 irreplaceable function in epidermal omega-O-acylceramide synthesis and skin permeability barrier. |
| Volume: |
26 |
| Issue: |
10 |
| Pages: |
1787-1800 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
711
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Golonzhka O |
| Year: |
2009 |
| Journal: |
J Invest Dermatol |
| Title: |
Dual role of COUP-TF-interacting protein 2 in epidermal homeostasis and permeability barrier formation. |
| Volume: |
129 |
| Issue: |
6 |
| Pages: |
1459-70 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang Z |
| Year: |
2013 |
| Journal: |
J Invest Dermatol |
| Title: |
Transcription factor Ctip2 controls epidermal lipid metabolism and regulates expression of genes involved in sphingolipid biosynthesis during skin development. |
| Volume: |
133 |
| Issue: |
3 |
| Pages: |
668-76 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Schwartz B |
| Year: |
2023 |
| Journal: |
J Invest Dermatol |
| Title: |
ZNF750 Regulates Skin Barrier Function by Driving Cornified Envelope and Lipid Processing Pathways. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
GO Central curators, GOA curators, Rhea curators |
| Year: |
2020 |
|
| Title: |
Automatic Gene Ontology annotation based on Rhea mapping |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
GOA curators, MGI curators |
| Year: |
2001 |
|
| Title: |
Gene Ontology annotation based on Enzyme Commission mapping |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
MGI and IMPC |
| Year: |
2018 |
| Journal: |
Database Release |
| Title: |
MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC) |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
The Gene Ontology Consortium |
| Year: |
2016 |
|
| Title: |
Automatic assignment of GO terms using logical inference, based on on inter-ontology links |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wellcome Trust Sanger Institute |
| Year: |
2009 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC) |
| Year: |
2014 |
| Journal: |
Database Release |
| Title: |
Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
The Gene Ontology Consortium |
| Year: |
2014 |
|
| Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
UniProt-GOA |
| Year: |
2012 |
|
| Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
DDB, FB, MGI, GOA, ZFIN curators |
| Year: |
2001 |
|
| Title: |
Gene Ontology annotation through association of InterPro records with GO terms |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Carninci P |
| Year: |
2005 |
| Journal: |
Science |
| Title: |
The transcriptional landscape of the mammalian genome. |
| Volume: |
309 |
| Issue: |
5740 |
| Pages: |
1559-63 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kawai J |
| Year: |
2001 |
| Journal: |
Nature |
| Title: |
Functional annotation of a full-length mouse cDNA collection. |
| Volume: |
409 |
| Issue: |
6821 |
| Pages: |
685-90 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Adams DJ |
| Year: |
2024 |
| Journal: |
Nature |
| Title: |
Genetic determinants of micronucleus formation in vivo. |
| Volume: |
627 |
| Issue: |
8002 |
| Pages: |
130-136 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
GemPharmatech |
| Year: |
2020 |
|
| Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Skarnes WC |
| Year: |
2011 |
| Journal: |
Nature |
| Title: |
A conditional knockout resource for the genome-wide study of mouse gene function. |
| Volume: |
474 |
| Issue: |
7351 |
| Pages: |
337-42 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
| Year: |
2008 |
| Journal: |
Database Download |
| Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
| Year: |
2011 |
|
| Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
| Year: |
2004 |
| Journal: |
Database Release |
| Title: |
Mouse T31 Radiation Hybrid Data Load |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Okazaki Y |
| Year: |
2002 |
| Journal: |
Nature |
| Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
| Volume: |
420 |
| Issue: |
6915 |
| Pages: |
563-73 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
The Gene Ontology Consortium |
| Year: |
2010 |
|
| Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
MGI Genome Annotation Group and UniGene Staff |
| Year: |
2015 |
| Journal: |
Database Download |
| Title: |
MGI-UniGene Interconnection Effort |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
| Year: |
2010 |
|
| Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
| Year: |
2000 |
| Journal: |
Database Release |
| Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Allen Institute for Brain Science |
| Year: |
2004 |
| Journal: |
Allen Institute |
| Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Group |
| Year: |
2003 |
| Journal: |
Database Procedure |
| Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bairoch A |
| Year: |
1999 |
| Journal: |
Database Release |
| Title: |
SWISS-PROT Annotated protein sequence database |
|
|
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| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
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| Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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| Publication |
| First Author: |
Mouse Genome Informatics |
| Year: |
2010 |
| Journal: |
Database Release |
| Title: |
Protein Ontology Association Load. |
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| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
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| Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
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| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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| UniProt Feature |
| Begin: |
1 |
| Description: |
Hydroperoxide isomerase ALOXE3 |
| Type: |
chain |
| End: |
711 |
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| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
380
 |
| Fragment?: |
false |
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| DO Term |
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| Publication |
| First Author: |
Moran JL |
| Year: |
2007 |
| Journal: |
J Invest Dermatol |
| Title: |
A mouse mutation in the 12R-lipoxygenase, Alox12b, disrupts formation of the epidermal permeability barrier. |
| Volume: |
127 |
| Issue: |
8 |
| Pages: |
1893-7 |
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| Publication |
| First Author: |
Church DM |
| Year: |
2009 |
| Journal: |
PLoS Biol |
| Title: |
Lineage-specific biology revealed by a finished genome assembly of the mouse. |
| Volume: |
7 |
| Issue: |
5 |
| Pages: |
e1000112 |
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