Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Adenomatous polyposis coli (APC) is a tumor suppressor protein that induces thedegradation of oncogenic beta-catenin and negatively regulates Wnt signalling []. It has roles in regulating cell migration, DNA replication/repair, mitosis and apoptosis [, ]. APC regulates cell-cell adhesion and cell migration through activating the APC-stimulated guanine nucleotide-exchange factor (GEF; Asef) [, ]. It acts as a mediator of ERBB2-dependent stabilisation of microtubules at the cell cortex []. It is required for the localisation of MACF1/ACF7 to the cell membrane and this localisation of MACF1/ACF7 is critical for its function in microtubule stabilisation []. APC mutations are particularly prevalent in colorectal cancer []. |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6502587 |
Assay Type: |
RNA in situ |
Annotation Date: |
2021-01-28 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1859021 |
Pattern: |
Regionally restricted |
Stage: |
TS21 |
Assay Id: |
MGI:6502635 |
Age: |
embryonic day 13.5 |
Image: |
4A Apc Vax2-/- |
Note: |
Expression lost specifically in the ventral retina. |
Specimen Label: |
4A Apc Vax2-/- |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6502587 |
Assay Type: |
RNA in situ |
Annotation Date: |
2021-01-28 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1859021 |
Pattern: |
Regionally restricted |
Stage: |
TS21 |
Assay Id: |
MGI:6502635 |
Age: |
embryonic day 13.5 |
Image: |
4A Apc WT |
Note: |
Strongest expression in retinal ganglion cell layer. |
Specimen Label: |
4A Apc WT |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
2845
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Powell SM |
Year: |
1992 |
Journal: |
Nature |
Title: |
APC mutations occur early during colorectal tumorigenesis. |
Volume: |
359 |
Issue: |
6392 |
Pages: |
235-7 |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Publication |
First Author: |
Lui C |
Year: |
2012 |
Journal: |
IUBMB Life |
Title: |
APC as a mobile scaffold: regulation and function at the nucleus, centrosomes, and mitochondria. |
Volume: |
64 |
Issue: |
3 |
Pages: |
209-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kawasaki Y |
Year: |
2000 |
Journal: |
Science |
Title: |
Asef, a link between the tumor suppressor APC and G-protein signaling. |
Volume: |
289 |
Issue: |
5482 |
Pages: |
1194-7 |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Publication |
First Author: |
Aoki K |
Year: |
2007 |
Journal: |
J Cell Sci |
Title: |
Adenomatous polyposis coli (APC): a multi-functional tumor suppressor gene. |
Volume: |
120 |
Issue: |
Pt 19 |
Pages: |
3327-35 |
|
•
•
•
•
•
|
Publication |
First Author: |
MacDonald BT |
Year: |
2009 |
Journal: |
Dev Cell |
Title: |
Wnt/beta-catenin signaling: components, mechanisms, and diseases. |
Volume: |
17 |
Issue: |
1 |
Pages: |
9-26 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang Z |
Year: |
2012 |
Journal: |
Cell Res |
Title: |
Structural basis for the recognition of Asef by adenomatous polyposis coli. |
Volume: |
22 |
Issue: |
2 |
Pages: |
372-86 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zaoui K |
Year: |
2010 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
ErbB2 receptor controls microtubule capture by recruiting ACF7 to the plasma membrane of migrating cells. |
Volume: |
107 |
Issue: |
43 |
Pages: |
18517-22 |
|
•
•
•
•
•
|
Publication |
First Author: |
Daly CS |
Year: |
2017 |
Journal: |
Oncogene |
Title: |
Functional redundancy between Apc and Apc2 regulates tissue homeostasis and prevents tumorigenesis in murine mammary epithelium. |
Volume: |
36 |
Issue: |
13 |
Pages: |
1793-1803 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
344
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
146
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
324
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
51
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
2842
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
2808
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1056
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1133
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
489
|
Fragment?: |
false |
|
•
•
•
•
•
|
CL Term |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1132
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
780
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
672
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
635
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
254
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
96
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
146
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
391
|
Fragment?: |
false |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
25
|
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
McCart AE |
Year: |
2008 |
Journal: |
Pathol Res Pract |
Title: |
Apc mice: models, modifiers and mutants. |
Volume: |
204 |
Issue: |
7 |
Pages: |
479-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zeineldin M |
Year: |
2013 |
Journal: |
Cancer Res |
Title: |
Understanding phenotypic variation in rodent models with germline Apc mutations. |
Volume: |
73 |
Issue: |
8 |
Pages: |
2389-99 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jung YS |
Year: |
2020 |
Journal: |
Hepatology |
Title: |
TMEM9-v-ATPase Activates Wnt/β-Catenin Signaling via APC Lysosomal Degradation for Liver Regeneration and Tumorigenesis. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Jacks T |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Generation of a conditional Apc allele |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Sansom OJ |
Year: |
2005 |
Journal: |
Oncogene |
Title: |
Apc deficiency predisposes to renal carcinoma in the mouse. |
Volume: |
24 |
Issue: |
55 |
Pages: |
8205-10 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6167542 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689421 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:6189790 |
Age: |
embryonic day 13.5 |
|
|
Specimen Label: |
Table S2 - E13.5 - Apc |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6167542 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689426 |
Pattern: |
Not Specified |
Stage: |
TS26 |
Assay Id: |
MGI:6189790 |
Age: |
embryonic day 18.5 |
|
|
Specimen Label: |
Table S2 - E18.5 - Apc |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6167542 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6189790 |
Age: |
postnatal day 14 |
|
|
Specimen Label: |
Table S2 - P14 - Apc |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6167542 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689419 |
Pattern: |
Not Specified |
Stage: |
TS19 |
Assay Id: |
MGI:6189790 |
Age: |
embryonic day 11.5 |
|
|
Specimen Label: |
Table S2 - E11.5 - Apc |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6167542 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689424 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:6189790 |
Age: |
embryonic day 15.5 |
|
|
Specimen Label: |
Table S2 - E15.5 - Apc |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6167542 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6189790 |
Age: |
postnatal day 4 |
|
|
Specimen Label: |
Table S2 - P4 - Apc |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6167542 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6189790 |
Age: |
postnatal day 28 |
|
|
Specimen Label: |
Table S2 - P28 - Apc |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wasan HS |
Year: |
1998 |
Journal: |
J Pathol |
Title: |
APC in the regulation of intestinal crypt fission. |
Volume: |
185 |
Issue: |
3 |
Pages: |
246-55 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fischer JM |
Year: |
2012 |
Journal: |
Oncogene |
Title: |
Different phenotypic consequences of simultaneous versus stepwise Apc loss. |
Volume: |
31 |
Issue: |
16 |
Pages: |
2028-38 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sansom OJ |
Year: |
2007 |
Journal: |
Nature |
Title: |
Myc deletion rescues Apc deficiency in the small intestine. |
Volume: |
446 |
Issue: |
7136 |
Pages: |
676-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Roose J |
Year: |
1999 |
Journal: |
Science |
Title: |
Synergy between tumor suppressor APC and the beta-catenin-Tcf4 target Tcf1. |
Volume: |
285 |
Issue: |
5435 |
Pages: |
1923-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Saito-Diaz K |
Year: |
2018 |
Journal: |
Dev Cell |
Title: |
APC Inhibits Ligand-Independent Wnt Signaling by the Clathrin Endocytic Pathway. |
Volume: |
44 |
Issue: |
5 |
Pages: |
566-581.e8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Levy DB |
Year: |
1994 |
Journal: |
Cancer Res |
Title: |
Inactivation of both APC alleles in human and mouse tumors. |
Volume: |
54 |
Issue: |
22 |
Pages: |
5953-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Benhamouche S |
Year: |
2006 |
Journal: |
Dev Cell |
Title: |
Apc tumor suppressor gene is the "zonation-keeper" of mouse liver. |
Volume: |
10 |
Issue: |
6 |
Pages: |
759-70 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bruxvoort KJ |
Year: |
2007 |
Journal: |
Cancer Res |
Title: |
Inactivation of Apc in the mouse prostate causes prostate carcinoma. |
Volume: |
67 |
Issue: |
6 |
Pages: |
2490-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Schatoff EM |
Year: |
2019 |
Journal: |
Cancer Discov |
Title: |
Distinct Colorectal Cancer-Associated APC Mutations Dictate Response to Tankyrase Inhibition. |
Volume: |
9 |
Issue: |
10 |
Pages: |
1358-1371 |
|
•
•
•
•
•
|
Publication |
First Author: |
Méniel V |
Year: |
2005 |
Journal: |
Cancer Res |
Title: |
Mutations in Apc and p53 synergize to promote mammary neoplasia. |
Volume: |
65 |
Issue: |
2 |
Pages: |
410-6 |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Publication |
First Author: |
Cheung AF |
Year: |
2010 |
Journal: |
Oncogene |
Title: |
Complete deletion of Apc results in severe polyposis in mice. |
Volume: |
29 |
Issue: |
12 |
Pages: |
1857-64 |
|
•
•
•
•
•
|
Publication |
First Author: |
Crist RC |
Year: |
2010 |
Journal: |
Mamm Genome |
Title: |
The armadillo repeat domain of Apc suppresses intestinal tumorigenesis. |
Volume: |
21 |
Issue: |
9-10 |
Pages: |
450-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu S |
Year: |
2017 |
Journal: |
Oncogene |
Title: |
Disruption of the RP-MDM2-p53 pathway accelerates APC loss-induced colorectal tumorigenesis. |
Volume: |
36 |
Issue: |
10 |
Pages: |
1374-1383 |
|
•
•
•
•
•
|
Publication |
First Author: |
He Z |
Year: |
2017 |
Journal: |
Sci Rep |
Title: |
Epithelial-derived IL-33 promotes intestinal tumorigenesis in Apc Min/+ mice. |
Volume: |
7 |
Issue: |
1 |
Pages: |
5520 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lapierre M |
Year: |
2014 |
Journal: |
J Clin Invest |
Title: |
RIP140 increases APC expression and controls intestinal homeostasis and tumorigenesis. |
Volume: |
124 |
Issue: |
5 |
Pages: |
1899-913 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pirone A |
Year: |
2017 |
Journal: |
Neurobiol Dis |
Title: |
APC conditional knock-out mouse is a model of infantile spasms with elevated neuronal β-catenin levels, neonatal spasms, and chronic seizures. |
Volume: |
98 |
|
Pages: |
149-157 |
|
•
•
•
•
•
|
Publication |
First Author: |
Prescott SM |
Year: |
1996 |
Journal: |
Cell |
Title: |
Self-promotion? Intimate connections between APC and prostaglandin H synthase-2. |
Volume: |
87 |
Issue: |
5 |
Pages: |
783-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hart MJ |
Year: |
1998 |
Journal: |
Curr Biol |
Title: |
Downregulation of beta-catenin by human Axin and its association with the APC tumor suppressor, beta-catenin and GSK3 beta. |
Volume: |
8 |
Issue: |
10 |
Pages: |
573-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
Eom TY |
Year: |
2014 |
Journal: |
Dev Cell |
Title: |
Differential regulation of microtubule severing by APC underlies distinct patterns of projection neuron and interneuron migration. |
Volume: |
31 |
Issue: |
6 |
Pages: |
677-89 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gaspar C |
Year: |
2009 |
Journal: |
PLoS Genet |
Title: |
A targeted constitutive mutation in the APC tumor suppressor gene underlies mammary but not intestinal tumorigenesis. |
Volume: |
5 |
Issue: |
7 |
Pages: |
e1000547 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sansom OJ |
Year: |
2004 |
Journal: |
Genes Dev |
Title: |
Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration. |
Volume: |
18 |
Issue: |
12 |
Pages: |
1385-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shibata H |
Year: |
1997 |
Journal: |
Science |
Title: |
Rapid colorectal adenoma formation initiated by conditional targeting of the Apc gene. |
Volume: |
278 |
Issue: |
5335 |
Pages: |
120-3 |
|
•
•
•
•
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Publication |
First Author: |
Cen B |
Year: |
2021 |
Journal: |
Oncogene |
Title: |
Mutant APC promotes tumor immune evasion via PD-L1 in colorectal cancer. |
Volume: |
40 |
Issue: |
41 |
Pages: |
5984-5992 |
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Publication |
First Author: |
Song JH |
Year: |
2014 |
Journal: |
Cell Rep |
Title: |
The APC network regulates the removal of mutated cells from colonic crypts. |
Volume: |
7 |
Issue: |
1 |
Pages: |
94-103 |
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Publication |
First Author: |
Li W |
Year: |
2013 |
Journal: |
Blood |
Title: |
Apc regulates the function of hematopoietic stem cells largely through β-catenin-dependent mechanisms. |
Volume: |
121 |
Issue: |
20 |
Pages: |
4063-72 |
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Publication |
First Author: |
Athineos D |
Year: |
2010 |
Journal: |
Oncogene |
Title: |
Myc heterozygosity attenuates the phenotypes of APC deficiency in the small intestine. |
Volume: |
29 |
Issue: |
17 |
Pages: |
2585-90 |
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Publication |
First Author: |
Bjerknes M |
Year: |
1997 |
Journal: |
Am J Pathol |
Title: |
APC mutation and the crypt cycle in murine and human intestine. |
Volume: |
150 |
Issue: |
3 |
Pages: |
833-9 |
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Publication |
First Author: |
Lewis A |
Year: |
2012 |
Journal: |
J Pathol |
Title: |
The C-terminus of Apc does not influence intestinal adenoma development or progression. |
Volume: |
226 |
Issue: |
1 |
Pages: |
73-83 |
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Publication |
First Author: |
Abal M |
Year: |
2007 |
Journal: |
Gastroenterology |
Title: |
APC inactivation associates with abnormal mitosis completion and concomitant BUB1B/MAD2L1 up-regulation. |
Volume: |
132 |
Issue: |
7 |
Pages: |
2448-58 |
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Publication |
First Author: |
Tao Y |
Year: |
2016 |
Journal: |
Carcinogenesis |
Title: |
Hsp70 exerts oncogenic activity in the Apc mutant Min mouse model. |
Volume: |
37 |
Issue: |
7 |
Pages: |
731-739 |
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Publication |
First Author: |
Pollard P |
Year: |
2009 |
Journal: |
Gastroenterology |
Title: |
The Apc 1322T mouse develops severe polyposis associated with submaximal nuclear beta-catenin expression. |
Volume: |
136 |
Issue: |
7 |
Pages: |
2204-2213.e1-13 |
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Publication |
First Author: |
Radulescu S |
Year: |
2012 |
Journal: |
Cell Rep |
Title: |
Luminal iron levels govern intestinal tumorigenesis after Apc loss in vivo. |
Volume: |
2 |
Issue: |
2 |
Pages: |
270-82 |
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Publication |
First Author: |
Foley TM |
Year: |
2017 |
Journal: |
Mol Cancer Res |
Title: |
Dual PI3K/mTOR Inhibition in Colorectal Cancers with APC and PIK3CA Mutations. |
Volume: |
15 |
Issue: |
3 |
Pages: |
317-327 |
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Publication |
First Author: |
Moser AR |
Year: |
1995 |
Journal: |
Dev Dyn |
Title: |
Homozygosity for the Min allele of Apc results in disruption of mouse development prior to gastrulation. |
Volume: |
203 |
Issue: |
4 |
Pages: |
422-33 |
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Publication |
First Author: |
Dow LE |
Year: |
2015 |
Journal: |
Cell |
Title: |
Apc Restoration Promotes Cellular Differentiation and Reestablishes Crypt Homeostasis in Colorectal Cancer. |
Volume: |
161 |
Issue: |
7 |
Pages: |
1539-1552 |
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