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Search results 1 to 100 out of 123 for Atp2c1

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0.045s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Domain
Type: Family
Description: ATP2C1 (also known as SPCA1) belongs to the IIA subfamily of P-type ATPases family, whose members are Ca2+ ATPases that catalyse the hydrolysis of ATP coupled with the transport of calcium across the membrane. ATP2C1 is a secretory pathway Ca-ATPase that shares significant homology to the yeast ATPase Pmr1, which is responsible for transporting calcium and manganese ions into the Golgi apparatus [, ].ATP2C1 is linked to the F-actin through cofilin, and this interaction promotes Ca2+-mediated secretory cargo sorting []. Mutations in ATP2C1 cause Hailey-Hailey disease (HHD), which is characterised by persistent blisters and erosions of the skin, due to impaired keratinocyte adhesion [, , , ].
Publication
First Author: Sudbrak R
Year: 2000
Journal: Hum Mol Genet
Title: Hailey-Hailey disease is caused by mutations in ATP2C1 encoding a novel Ca(2+) pump.
Volume: 9
Issue: 7
Pages: 1131-40
Publication
First Author: Dobson-Stone C
Year: 2002
Journal: J Invest Dermatol
Title: Hailey-Hailey disease: molecular and clinical characterization of novel mutations in the ATP2C1 gene.
Volume: 118
Issue: 2
Pages: 338-43
Publication
First Author: Yokota K
Year: 2002
Journal: J Invest Dermatol
Title: Analysis of ATP2C1 gene mutation in 10 unrelated Japanese families with Hailey-Hailey disease.
Volume: 118
Issue: 3
Pages: 550-1
Publication
First Author: Okunade GW
Year: 2007
Journal: J Biol Chem
Title: Loss of the Atp2c1 secretory pathway Ca(2+)-ATPase (SPCA1) in mice causes Golgi stress, apoptosis, and midgestational death in homozygous embryos and squamous cell tumors in adult heterozygotes.
Volume: 282
Issue: 36
Pages: 26517-27
Publication
First Author: Hu Z
Year: 2000
Journal: Nat Genet
Title: Mutations in ATP2C1, encoding a calcium pump, cause Hailey-Hailey disease.
Volume: 24
Issue: 1
Pages: 61-5
Publication
First Author: Devasahayam G
Year: 2007
Journal: Genetics
Title: Golgi manganese transport is required for rapamycin signaling in Saccharomyces cerevisiae.
Volume: 177
Issue: 1
Pages: 231-8
Publication
First Author: Kienzle C
Year: 2014
Journal: J Cell Biol
Title: Cofilin recruits F-actin to SPCA1 and promotes Ca2+-mediated secretory cargo sorting.
Volume: 206
Issue: 5
Pages: 635-54
Publication
First Author: Pestov NB
Year: 2012
Journal: Biochem Biophys Res Commun
Title: Structural evolution and tissue-specific expression of tetrapod-specific second isoform of secretory pathway Ca2+-ATPase.
Volume: 417
Issue: 4
Pages: 1298-303
Protein
Organism: Mus musculus
Length: 111  
Fragment?: true
Protein
Organism: Mus musculus
Length: 183  
Fragment?: false
Protein
Organism: Mus musculus
Length: 253  
Fragment?: true
Protein
Organism: Mus musculus
Length: 230  
Fragment?: true
Protein
Organism: Mus musculus
Length: 177  
Fragment?: true
Protein
Organism: Mus musculus
Length: 208  
Fragment?: true
Protein
Organism: Mus musculus
Length: 456  
Fragment?: false
Protein
Organism: Mus musculus
Length: 918  
Fragment?: false
Protein
Organism: Mus musculus
Length: 669  
Fragment?: false
Protein
Organism: Mus musculus
Length: 887  
Fragment?: false
Protein
Organism: Mus musculus
Length: 786  
Fragment?: true
Protein
Organism: Mus musculus
Length: 915  
Fragment?: true
Protein
Organism: Mus musculus
Length: 926  
Fragment?: false
Protein
Organism: Mus musculus
Length: 917  
Fragment?: false
Protein
Organism: Mus musculus
Length: 952  
Fragment?: false
Publication
First Author: Shull GE
Year: 2011
Journal: Biofactors
Title: Secretory pathway stress responses as possible mechanisms of disease involving Golgi Ca2+ pump dysfunction.
Volume: 37
Issue: 3
Pages: 150-8
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: SepĂșlveda MR
Year: 2009
Journal: J Neurosci
Title: Silencing the SPCA1 (secretory pathway Ca2+-ATPase isoform 1) impairs Ca2+ homeostasis in the Golgi and disturbs neural polarity.
Volume: 29
Issue: 39
Pages: 12174-82
GXD Expression    
Probe: MGI:3723231
Assay Type: Northern blot
Annotation Date: 2007-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1775928
Stage: TS28
Assay Id: MGI:3723236
Age: postnatal adult
Image: 1
Specimen Label: Mamm +/+
Detected: true
Specimen Num: 13
GXD Expression    
Probe: MGI:3723231
Assay Type: Northern blot
Annotation Date: 2007-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1775928
Stage: TS28
Assay Id: MGI:3723236
Age: postnatal adult
Image: 1
Specimen Label: Mamm +/-
Detected: true
Specimen Num: 14
GXD Expression    
Probe: MGI:3723321
Assay Type: RT-PCR
Annotation Date: 2007-10-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2576528
Stage: TS28
Assay Id: MGI:3723322
Age: postnatal adult
Image: 1
Specimen Label: +/+
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3723321
Assay Type: RT-PCR
Annotation Date: 2007-10-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2576528
Stage: TS28
Assay Id: MGI:3723322
Age: postnatal adult
Image: 1
Specimen Label: +/-
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:3723231
Assay Type: Northern blot
Annotation Date: 2007-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:3723236
Age: postnatal adult
Image: 1
Specimen Label: Lung +/+
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:3723231
Assay Type: Northern blot
Annotation Date: 2007-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:3723236
Age: postnatal adult
Image: 1
Specimen Label: Lung +/-
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:3723231
Assay Type: Northern blot
Annotation Date: 2007-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3723236
Age: postnatal adult
Image: 1
Specimen Label: Heart +/+
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:3723231
Assay Type: Northern blot
Annotation Date: 2007-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3723236
Age: postnatal adult
Image: 1
Specimen Label: Heart +/-
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:3723233
Assay Type: Western blot
Annotation Date: 2007-10-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3723346
Age: postnatal adult
Image: 3
Specimen Label: +/+
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3723233
Assay Type: Western blot
Annotation Date: 2007-10-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3723346
Age: postnatal adult
Image: 3
Specimen Label: +/-
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:3723233
Assay Type: Western blot
Annotation Date: 2007-10-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3723346
Age: postnatal adult
Image: 3
Specimen Label: +/+
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:3723233
Assay Type: Western blot
Annotation Date: 2007-10-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3723346
Age: postnatal adult
Image: 3
Specimen Label: +/-
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:3723233
Assay Type: Western blot
Annotation Date: 2007-10-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3723346
Age: postnatal adult
Image: 3
Specimen Label: +/+
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:3723233
Assay Type: Western blot
Annotation Date: 2007-10-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3723346
Age: postnatal adult
Image: 3
Specimen Label: +/-
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:3723323
Assay Type: RT-PCR
Annotation Date: 2007-10-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:3723337
Age: embryonic day 8.5
Image: 2
Specimen Label: +/-
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:3723323
Assay Type: RT-PCR
Annotation Date: 2007-10-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:3723337
Age: embryonic day 8.5
Image: 2
Specimen Label: -/-
Detected: false
Specimen Num: 3
GXD Expression    
Probe: MGI:3723323
Assay Type: RT-PCR
Annotation Date: 2007-10-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:3723337
Age: embryonic day 8.5
Image: 2
Specimen Label: -/-
Detected: false
Specimen Num: 4
GXD Expression    
Probe: MGI:3723323
Assay Type: RT-PCR
Annotation Date: 2007-10-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:3723337
Age: embryonic day 8.5
Image: 2
Specimen Label: +/+
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:3723324
Assay Type: RT-PCR
Annotation Date: 2007-10-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:3723340
Age: embryonic day 8.5
Image: 2
Specimen Label: +/-
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:3723324
Assay Type: RT-PCR
Annotation Date: 2007-10-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:3723340
Age: embryonic day 8.5
Image: 2
Specimen Label: -/-
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:3723324
Assay Type: RT-PCR
Annotation Date: 2007-10-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:3723340
Age: embryonic day 8.5
Image: 2
Specimen Label: -/-
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:3723324
Assay Type: RT-PCR
Annotation Date: 2007-10-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:3723340
Age: embryonic day 8.5
Image: 2
Specimen Label: +/+
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:3723231
Assay Type: Northern blot
Annotation Date: 2007-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3723236
Age: postnatal adult
Image: 1
Specimen Label: Liver +/+
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:3723231
Assay Type: Northern blot
Annotation Date: 2007-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3723236
Age: postnatal adult
Image: 1
Specimen Label: Liver +/-
Detected: true
Specimen Num: 10
GXD Expression    
Probe: MGI:3723231
Assay Type: Northern blot
Annotation Date: 2007-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1893928
Stage: TS28
Assay Id: MGI:3723236
Age: postnatal adult
Image: 1
Specimen Label: Colon +/+
Detected: true
Specimen Num: 11
GXD Expression    
Probe: MGI:3723231
Assay Type: Northern blot
Annotation Date: 2007-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1893928
Stage: TS28
Assay Id: MGI:3723236
Age: postnatal adult
Image: 1
Specimen Label: Colon +/-
Detected: true
Specimen Num: 12
GXD Expression    
Probe: MGI:3723231
Assay Type: Northern blot
Annotation Date: 2007-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1702128
Stage: TS28
Assay Id: MGI:3723236
Age: postnatal adult
Image: 1
Specimen Label: Stom +/+
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:3723231
Assay Type: Northern blot
Annotation Date: 2007-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1702128
Stage: TS28
Assay Id: MGI:3723236
Age: postnatal adult
Image: 1
Specimen Label: Stom +/-
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:3723231
Assay Type: Northern blot
Annotation Date: 2007-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3723236
Age: postnatal adult
Image: 1
Specimen Label: Brain +/+
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3723231
Assay Type: Northern blot
Annotation Date: 2007-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3723236
Age: postnatal adult
Image: 1
Specimen Label: Brain +/-
Detected: true
Specimen Num: 2
Publication    
First Author: Mitchell KJ
Year: 2003
Journal: GenBank Submission
Title: Mus musculus mRNA for PMR1/ATP2C1 protein (pmr1 gene)
Pages: AJ551270
Publication
First Author: Feng M
Year: 2010
Journal: Cell
Title: Store-independent activation of Orai1 by SPCA2 in mammary tumors.
Volume: 143
Issue: 1
Pages: 84-98
Publication
First Author: Cross BM
Year: 2013
Journal: PLoS One
Title: SPCA2 regulates Orai1 trafficking and store independent Ca2+ entry in a model of lactation.
Volume: 8
Issue: 6
Pages: e67348
Publication
First Author: Shull GE
Year: 2000
Journal: Eur J Biochem
Title: Gene knockout studies of Ca2+-transporting ATPases.
Volume: 267
Issue: 17
Pages: 5284-90
Publication  
First Author: Brown JM
Year: 2018
Journal: Development
Title: Secretory pathway calcium ATPase 1 (SPCA1) controls mouse neural tube closure by regulating cytoskeletal dynamics.
Volume: 145
Issue: 19
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: MGC Data curation in Mouse Genome Informatics
Publication        
First Author: Mouse Genome Database and National Center for Biotechnology Information Editorial Staff Collaboration
Year: 2001
Title: LocusLink Collaboration
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
Publication
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication      
First Author: GemPharmatech
Year: 2020
Journal: website
Title: GemPharmatech website