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Search results 1 to 100 out of 131 for Atp2c1

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Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
27032 | ATP2C1
Type: gene
Organism: human
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Gene
100487845 | atp2c1
Type: gene
Organism: frog, western clawed
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Gene
170699 | Atp2c1
Type: gene
Organism: rat
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Gene
460694 | ATP2C1
Type: gene
Organism: chimpanzee
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Gene
477066 | ATP2C1
Type: gene
Organism: dog, domestic
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Gene
327663 | ATP2C1
Type: gene
Organism: cattle
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Gene
428450 | ATP2C1
Type: gene
Organism: chicken
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Gene
559574 | atp2c1
Type: gene
Organism: zebrafish
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Gene
719281 | ATP2C1
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:1889008 | Atp2c1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR030336 | ATP2C1
Type: Family
Description: ATP2C1 (also known as SPCA1) belongs to the IIA subfamily of P-type ATPases family, whose members are Ca2+ ATPases that catalyse the hydrolysis of ATP coupled with the transport of calcium across the membrane. ATP2C1 is a secretory pathway Ca-ATPase that shares significant homology to the yeast ATPase Pmr1, which is responsible for transporting calcium and manganese ions into the Golgi apparatus [, ].ATP2C1 is linked to the F-actin through cofilin, and this interaction promotes Ca2+-mediated secretory cargo sorting []. Mutations in ATP2C1 cause Hailey-Hailey disease (HHD), which is characterised by persistent blisters and erosions of the skin, due to impaired keratinocyte adhesion [, , , ].
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Publication
10767338 | J:61778
First Author: Sudbrak R
Year: 2000
Journal: Hum Mol Genet
Title: Hailey-Hailey disease is caused by mutations in ATP2C1 encoding a novel Ca(2+) pump.
Volume: 9
Issue: 7
Pages: 1131-40
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Publication
11841554 | -
First Author: Dobson-Stone C
Year: 2002
Journal: J Invest Dermatol
Title: Hailey-Hailey disease: molecular and clinical characterization of novel mutations in the ATP2C1 gene.
Volume: 118
Issue: 2
Pages: 338-43
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Publication
11874499 | -
First Author: Yokota K
Year: 2002
Journal: J Invest Dermatol
Title: Analysis of ATP2C1 gene mutation in 10 unrelated Japanese families with Hailey-Hailey disease.
Volume: 118
Issue: 3
Pages: 550-1
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Publication
17597066 | J:124662
First Author: Okunade GW
Year: 2007
Journal: J Biol Chem
Title: Loss of the Atp2c1 secretory pathway Ca(2+)-ATPase (SPCA1) in mice causes Golgi stress, apoptosis, and midgestational death in homozygous embryos and squamous cell tumors in adult heterozygotes.
Volume: 282
Issue: 36
Pages: 26517-27
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Publication
10615129 | -
First Author: Hu Z
Year: 2000
Journal: Nat Genet
Title: Mutations in ATP2C1, encoding a calcium pump, cause Hailey-Hailey disease.
Volume: 24
Issue: 1
Pages: 61-5
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Publication
17603109 | -
First Author: Devasahayam G
Year: 2007
Journal: Genetics
Title: Golgi manganese transport is required for rapamycin signaling in Saccharomyces cerevisiae.
Volume: 177
Issue: 1
Pages: 231-8
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Publication
25179631 | -
First Author: Kienzle C
Year: 2014
Journal: J Cell Biol
Title: Cofilin recruits F-actin to SPCA1 and promotes Ca2+-mediated secretory cargo sorting.
Volume: 206
Issue: 5
Pages: 635-54
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Publication
22240025 | -
First Author: Pestov NB
Year: 2012
Journal: Biochem Biophys Res Commun
Title: Structural evolution and tissue-specific expression of tetrapod-specific second isoform of secretory pathway Ca2+-ATPase.
Volume: 417
Issue: 4
Pages: 1298-303
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Protein
H3BJ99
Organism: Mus musculus/domesticus
Length: 111  
Fragment?: true
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Protein
Q3UWW0
Organism: Mus musculus/domesticus
Length: 183  
Fragment?: false
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Protein
H3BLC2
Organism: Mus musculus/domesticus
Length: 253  
Fragment?: true
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Protein
H3BJY0
Organism: Mus musculus/domesticus
Length: 230  
Fragment?: true
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Protein
H3BJJ5
Organism: Mus musculus/domesticus
Length: 177  
Fragment?: true
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Protein
H3BKB1
Organism: Mus musculus/domesticus
Length: 208  
Fragment?: true
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Protein
Q3TTD2
Organism: Mus musculus/domesticus
Length: 456  
Fragment?: false
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Protein
Q80XR2
Organism: Mus musculus/domesticus
Length: 918  
Fragment?: false
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Protein
Q8BMS7
Organism: Mus musculus/domesticus
Length: 669  
Fragment?: false
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Protein
H3BL44
Organism: Mus musculus/domesticus
Length: 887  
Fragment?: false
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Protein
H3BLI6
Organism: Mus musculus/domesticus
Length: 786  
Fragment?: true
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Protein
Q69ZL4
Organism: Mus musculus/domesticus
Length: 915  
Fragment?: true
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Protein
H3BIX7
Organism: Mus musculus/domesticus
Length: 926  
Fragment?: false
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Protein
Q3TVY6
Organism: Mus musculus/domesticus
Length: 917  
Fragment?: false
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Protein
Q3UZR5
Organism: Mus musculus/domesticus
Length: 952  
Fragment?: false
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Publication
21674634 | J:194388
First Author: Shull GE
Year: 2011
Journal: Biofactors
Title: Secretory pathway stress responses as possible mechanisms of disease involving Golgi Ca2+ pump dysfunction.
Volume: 37
Issue: 3
Pages: 150-8
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Protein Coding Gene
MGP_CAROLIEiJ_G0032606 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0035215 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0035195 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0035127 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0035188 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0034898 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1889008 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0035708 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0034210 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0034867 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0035028 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0034976 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0035104 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0035015 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0035730 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0033917 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0034330 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0015474 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0033752 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
19793975 | J:153251
First Author: Sepúlveda MR
Year: 2009
Journal: J Neurosci
Title: Silencing the SPCA1 (secretory pathway Ca2+-ATPase isoform 1) impairs Ca2+ homeostasis in the Golgi and disturbs neural polarity.
Volume: 29
Issue: 39
Pages: 12174-82
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GXD Expression
GXD Expression
   
Probe: MGI:3723231
Assay Type: Northern blot
Annotation Date: 2007-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3723236
Age: postnatal adult
Image: 1
Specimen Label: Brain +/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:3723231
Assay Type: Northern blot
Annotation Date: 2007-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3723236
Age: postnatal adult
Image: 1
Specimen Label: Brain +/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:3723231
Assay Type: Northern blot
Annotation Date: 2007-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3723236
Age: postnatal adult
Image: 1
Specimen Label: Heart +/+
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:3723231
Assay Type: Northern blot
Annotation Date: 2007-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3723236
Age: postnatal adult
Image: 1
Specimen Label: Heart +/-
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:3723231
Assay Type: Northern blot
Annotation Date: 2007-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:3723236
Age: postnatal adult
Image: 1
Specimen Label: Lung +/+
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:3723231
Assay Type: Northern blot
Annotation Date: 2007-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:3723236
Age: postnatal adult
Image: 1
Specimen Label: Lung +/-
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:3723231
Assay Type: Northern blot
Annotation Date: 2007-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1702128
Stage: TS28
Assay Id: MGI:3723236
Age: postnatal adult
Image: 1
Specimen Label: Stom +/+
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
   
Probe: MGI:3723231
Assay Type: Northern blot
Annotation Date: 2007-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1702128
Stage: TS28
Assay Id: MGI:3723236
Age: postnatal adult
Image: 1
Specimen Label: Stom +/-
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
   
Probe: MGI:3723231
Assay Type: Northern blot
Annotation Date: 2007-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3723236
Age: postnatal adult
Image: 1
Specimen Label: Liver +/+
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
   
Probe: MGI:3723231
Assay Type: Northern blot
Annotation Date: 2007-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3723236
Age: postnatal adult
Image: 1
Specimen Label: Liver +/-
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
   
Probe: MGI:3723231
Assay Type: Northern blot
Annotation Date: 2007-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1893928
Stage: TS28
Assay Id: MGI:3723236
Age: postnatal adult
Image: 1
Specimen Label: Colon +/+
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
   
Probe: MGI:3723231
Assay Type: Northern blot
Annotation Date: 2007-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1893928
Stage: TS28
Assay Id: MGI:3723236
Age: postnatal adult
Image: 1
Specimen Label: Colon +/-
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
   
Probe: MGI:3723231
Assay Type: Northern blot
Annotation Date: 2007-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1775928
Stage: TS28
Assay Id: MGI:3723236
Age: postnatal adult
Image: 1
Specimen Label: Mamm +/+
Detected: true
Specimen Num: 13
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GXD Expression
GXD Expression
   
Probe: MGI:3723231
Assay Type: Northern blot
Annotation Date: 2007-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1775928
Stage: TS28
Assay Id: MGI:3723236
Age: postnatal adult
Image: 1
Specimen Label: Mamm +/-
Detected: true
Specimen Num: 14
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GXD Expression
GXD Expression
   
Probe: MGI:3723321
Assay Type: RT-PCR
Annotation Date: 2007-10-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2576528
Stage: TS28
Assay Id: MGI:3723322
Age: postnatal adult
Image: 1
Specimen Label: +/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:3723321
Assay Type: RT-PCR
Annotation Date: 2007-10-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2576528
Stage: TS28
Assay Id: MGI:3723322
Age: postnatal adult
Image: 1
Specimen Label: +/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:3723323
Assay Type: RT-PCR
Annotation Date: 2007-10-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:3723337
Age: embryonic day 8.5
Image: 2
Specimen Label: +/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:3723323
Assay Type: RT-PCR
Annotation Date: 2007-10-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:3723337
Age: embryonic day 8.5
Image: 2
Specimen Label: -/-
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:3723323
Assay Type: RT-PCR
Annotation Date: 2007-10-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:3723337
Age: embryonic day 8.5
Image: 2
Specimen Label: -/-
Detected: false
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:3723323
Assay Type: RT-PCR
Annotation Date: 2007-10-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:3723337
Age: embryonic day 8.5
Image: 2
Specimen Label: +/+
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:3723324
Assay Type: RT-PCR
Annotation Date: 2007-10-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:3723340
Age: embryonic day 8.5
Image: 2
Specimen Label: +/-
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:3723324
Assay Type: RT-PCR
Annotation Date: 2007-10-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:3723340
Age: embryonic day 8.5
Image: 2
Specimen Label: -/-
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
   
Probe: MGI:3723324
Assay Type: RT-PCR
Annotation Date: 2007-10-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:3723340
Age: embryonic day 8.5
Image: 2
Specimen Label: -/-
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
   
Probe: MGI:3723324
Assay Type: RT-PCR
Annotation Date: 2007-10-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:3723340
Age: embryonic day 8.5
Image: 2
Specimen Label: +/+
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
   
Probe: MGI:3723233
Assay Type: Western blot
Annotation Date: 2007-10-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3723346
Age: postnatal adult
Image: 3
Specimen Label: +/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:3723233
Assay Type: Western blot
Annotation Date: 2007-10-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3723346
Age: postnatal adult
Image: 3
Specimen Label: +/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:3723233
Assay Type: Western blot
Annotation Date: 2007-10-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3723346
Age: postnatal adult
Image: 3
Specimen Label: +/+
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:3723233
Assay Type: Western blot
Annotation Date: 2007-10-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3723346
Age: postnatal adult
Image: 3
Specimen Label: +/-
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:3723233
Assay Type: Western blot
Annotation Date: 2007-10-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3723346
Age: postnatal adult
Image: 3
Specimen Label: +/+
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:3723233
Assay Type: Western blot
Annotation Date: 2007-10-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3723346
Age: postnatal adult
Image: 3
Specimen Label: +/-
Detected: true
Specimen Num: 6
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Publication
- | J:83426
   
First Author: Mitchell KJ
Year: 2003
Journal: GenBank Submission
Title: Mus musculus mRNA for PMR1/ATP2C1 protein (pmr1 gene)
Pages: AJ551270
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Publication
20887894 | J:167918
First Author: Feng M
Year: 2010
Journal: Cell
Title: Store-independent activation of Orai1 by SPCA2 in mammary tumors.
Volume: 143
Issue: 1
Pages: 84-98
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Publication
23840669 | J:203715
First Author: Cross BM
Year: 2013
Journal: PLoS One
Title: SPCA2 regulates Orai1 trafficking and store independent Ca2+ entry in a model of lactation.
Volume: 8
Issue: 6
Pages: e67348
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Publication
10951186 | J:64183
First Author: Shull GE
Year: 2000
Journal: Eur J Biochem
Title: Gene knockout studies of Ca2+-transporting ATPases.
Volume: 267
Issue: 17
Pages: 5284-90
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Publication
30228103 | J:266546
 
First Author: Brown JM
Year: 2018
Journal: Development
Title: Secretory pathway calcium ATPase 1 (SPCA1) controls mouse neural tube closure by regulating cytoskeletal dynamics.
Volume: 145
Issue: 19
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Publication
- | J:77000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: MGC Data curation in Mouse Genome Informatics
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Publication
- | J:66660
       
First Author: Mouse Genome Database and National Center for Biotechnology Information Editorial Staff Collaboration
Year: 2001
Title: LocusLink Collaboration
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Publication
- | J:81858
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
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Publication
17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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Publication
- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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