| Type |
Details |
Score |
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, western clawed |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
dog, domestic |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chimpanzee |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
cattle |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chicken |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
zebrafish |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
Carbonic anhydrases (CA: ) are zinc metalloenzymes whichcatalyse the reversible hydration of carbon dioxide to bicarbonate [, ]. CAs have essential roles in facilitating the transport of carbon dioxide and protons in the intracellular space, across biological membranes and in the layers of the extracellular space; they are also involved in many other processes, from respiration and photosynthesis in eukaryotes to cyanate degradation in prokaryotes. There are five known evolutionarily distinct CA families (alpha, beta, gamma, delta and epsilon) that have no significant sequence identity and have structurally distinct overall folds. Some CAs are membrane-bound, while others act in the cytosol; there are several related proteins that lack enzymatic activity. The active site of alpha-CAs is well described, consisting of a zinc ion coordinated through 3 histidine residues and a water molecule/hydroxide ion that acts as a potent nucleophile. The enzyme employs a two-step mechanism: in the first step, there is a nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide; in the second step, the active site is regenerated by the ionisation of the zinc-bound water molecule and the removal of a proton from the active site []. Beta- and gamma-CAs also employ a zinc hydroxide mechanism, although at least some beta-class enzymes do not have water directly coordinated to the metal ion. The alpha-CAs are found predominantly in animals but also in bacteria and green algae. There are at least 15 isoforms found in mammals, which can be subdivided into cytosolic CAs (CA-I, CA-II, CA-III, CA-VII and CA XIII), mitochondrial CAs (CA-VA and CA-VB), secreted CAs (CA-VI), membrane-associated (CA-IV, CA-IX, CA-XII and CA-XIV) and those without CA activity, the CA-related proteins (CA-RP VIII, X and XI).The beta-CAs are highly abundant in plants, diatoms, eubacteria and archaea [, ]. The beta-CAs are far more diverse in sequence than other classes, and can be divided into different clades based on sequence identity, with the plant enzymes forming two clades representing dicotyledonous and monocotyledonous plants. Characterisation of these enzymes reveals sharp differences between the beta class, which forms dimers, tetramers, hexamers and octomers, and the alpha and gamma classes, which form strictly monomers and trimers. The gamma-CAs may be the most ancient form of carbonic anhydrases, having evolved long before the alpha class, to which it is more closely related than to the beta-class [, ]. The reaction mechanism of the gamma-class is similar to that of the alpha-class, even though the overall folds are dissimilar and the active site residues differ. The delta-CAs are found in marine algae and dinoflagellates []. The epsilon-CAs are found in prokaryotes such as Thiobacillus neapolitanus (Halothiobacillus neapolitanus) in which it is a component of the carboxysome shell, where it could supply the active sites of RuBisCO in the carboxysome with the high concentrations of carbon dioxide necessary for optimal RuBisCO activity and efficient carbon fixation [].This entry represents carbonic anhydrase 9 []. CA9 s a hypoxia-regulated, transmembrane protein associated with neoplastic growth in a large spectrum of human tumours []. |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hilvo M |
| Year: |
2008 |
| Journal: |
J Biol Chem |
| Title: |
Biochemical characterization of CA IX, one of the most active carbonic anhydrase isozymes. |
| Volume: |
283 |
| Issue: |
41 |
| Pages: |
27799-809 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sedlakova O |
| Year: |
2014 |
| Journal: |
Front Physiol |
| Title: |
Carbonic anhydrase IX, a hypoxia-induced catalytic component of the pH regulating machinery in tumors. |
| Volume: |
4 |
|
| Pages: |
400 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
437
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
256
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
237
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
339
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
437
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lindskog S |
| Year: |
1997 |
| Journal: |
Pharmacol Ther |
| Title: |
Structure and mechanism of carbonic anhydrase. |
| Volume: |
74 |
| Issue: |
1 |
| Pages: |
1-20 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Supuran CT |
| Year: |
2008 |
| Journal: |
Curr Pharm Des |
| Title: |
Carbonic anhydrases--an overview. |
| Volume: |
14 |
| Issue: |
7 |
| Pages: |
603-14 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Smith KS |
| Year: |
2000 |
| Journal: |
FEMS Microbiol Rev |
| Title: |
Prokaryotic carbonic anhydrases. |
| Volume: |
24 |
| Issue: |
4 |
| Pages: |
335-66 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sawaya MR |
| Year: |
2006 |
| Journal: |
J Biol Chem |
| Title: |
The structure of beta-carbonic anhydrase from the carboxysomal shell reveals a distinct subclass with one active site for the price of two. |
| Volume: |
281 |
| Issue: |
11 |
| Pages: |
7546-55 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Smith KS |
| Year: |
2002 |
| Journal: |
J Bacteriol |
| Title: |
Roles of the conserved aspartate and arginine in the catalytic mechanism of an archaeal beta-class carbonic anhydrase. |
| Volume: |
184 |
| Issue: |
15 |
| Pages: |
4240-5 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Fu X |
| Year: |
2008 |
| Journal: |
Mol Phylogenet Evol |
| Title: |
Evolution of structure in gamma-class carbonic anhydrase and structurally related proteins. |
| Volume: |
47 |
| Issue: |
1 |
| Pages: |
211-20 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zimmerman SA |
| Year: |
2008 |
| Journal: |
Curr Pharm Des |
| Title: |
The beta and gamma classes of carbonic anhydrase. |
| Volume: |
14 |
| Issue: |
7 |
| Pages: |
716-21 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lapointe M |
| Year: |
2008 |
| Journal: |
Plant Physiol |
| Title: |
An external delta-carbonic anhydrase in a free-living marine dinoflagellate may circumvent diffusion-limited carbon acquisition. |
| Volume: |
147 |
| Issue: |
3 |
| Pages: |
1427-36 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
So AK |
| Year: |
2004 |
| Journal: |
J Bacteriol |
| Title: |
A novel evolutionary lineage of carbonic anhydrase (epsilon class) is a component of the carboxysome shell. |
| Volume: |
186 |
| Issue: |
3 |
| Pages: |
623-30 |
|
•
•
•
•
•
|
| Allele |
| Name: |
carbonic anhydrase 9; targeted mutation 1, Shanghai Model Organisms Center |
| Allele Type: |
Targeted |
| Attribute String: |
Humanized sequence, Inserted expressed sequence |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Alsady M |
| Year: |
2018 |
| Journal: |
Am J Physiol Renal Physiol |
| Title: |
Lithium induces aerobic glycolysis and glutaminolysis in collecting duct principal cells. |
| Volume: |
314 |
| Issue: |
2 |
| Pages: |
F230-F239 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jiang W |
| Year: |
1999 |
| Journal: |
Biochem J |
| Title: |
Structure of the carbonic anhydrase VI (CA6) gene: evidence for two distinct groups within the alpha-CA gene family. |
| Volume: |
344 Pt 2 |
|
| Pages: |
385-90 |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus caroli |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus pahari |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gut MO |
| Year: |
2002 |
| Journal: |
Gastroenterology |
| Title: |
Gastric hyperplasia in mice with targeted disruption of the carbonic anhydrase gene Car9. |
| Volume: |
123 |
| Issue: |
6 |
| Pages: |
1889-903 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Leppilampi M |
| Year: |
2005 |
| Journal: |
Transgenic Res |
| Title: |
Gastric pit cell hyperplasia and glandular atrophy in carbonic anhydrase IX knockout mice: studies on two strains C57/BL6 and BALB/C. |
| Volume: |
14 |
| Issue: |
5 |
| Pages: |
655-63 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Demandt JAF |
| Year: |
2021 |
| Journal: |
Sci Rep |
| Title: |
The hypoxia-sensor carbonic anhydrase IX affects macrophage metabolism, but is not a suitable biomarker for human cardiovascular disease. |
| Volume: |
11 |
| Issue: |
1 |
| Pages: |
425 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Pan PW |
| Year: |
2012 |
| Journal: |
Transgenic Res |
| Title: |
Brain phenotype of carbonic anhydrase IX-deficient mice. |
| Volume: |
21 |
| Issue: |
1 |
| Pages: |
163-76 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kallio H |
| Year: |
2010 |
| Journal: |
BMC Genomics |
| Title: |
Global transcriptional response to carbonic anhydrase IX deficiency in the mouse stomach. |
| Volume: |
11 |
|
| Pages: |
397 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hilvo M |
| Year: |
2004 |
| Journal: |
J Histochem Cytochem |
| Title: |
Expression of carbonic anhydrase IX in mouse tissues. |
| Volume: |
52 |
| Issue: |
10 |
| Pages: |
1313-22 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4836254 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2010-10-27 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1689428 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:4836492 |
| Age: |
postnatal |
|
|
| Specimen Label: |
WT |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4836254 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2010-10-27 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1689428 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:4836492 |
| Age: |
postnatal |
|
|
| Specimen Label: |
FIH KO |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6393659 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2020-03-10 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:3570528 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:6393678 |
| Age: |
postnatal adult |
| Image: |
1 |
|
| Specimen Label: |
GV |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6393659 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2020-03-10 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:3575528 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:6393678 |
| Age: |
postnatal adult |
| Image: |
1 |
|
| Specimen Label: |
MII 16h |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6393659 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2020-03-10 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:160331 |
|
| Stage: |
TS01 |
| Assay Id: |
MGI:6393678 |
| Age: |
embryonic day 0.5 |
| Image: |
1 |
|
| Specimen Label: |
Zygote |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6393659 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2020-03-10 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:160362 |
|
| Stage: |
TS02 |
| Assay Id: |
MGI:6393678 |
| Age: |
embryonic day 1.5 |
| Image: |
1 |
|
| Specimen Label: |
2-cell |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7543804 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2023-11-20 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1610528 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7549309 |
| Age: |
postnatal week 10 |
| Image: |
1 |
|
| Specimen Label: |
Heart |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7543804 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2023-11-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1672828 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7549309 |
| Age: |
postnatal week 10 |
| Image: |
1 |
|
| Specimen Label: |
Lung |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7543804 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2023-11-20 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1684628 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7549309 |
| Age: |
postnatal week 10 |
| Image: |
1 |
|
| Specimen Label: |
Liver |
| Detected: |
false |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7543804 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2023-11-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1737328 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7549309 |
| Age: |
postnatal week 10 |
| Image: |
1 |
|
| Specimen Label: |
Kidney |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7543804 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2023-11-20 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1876728 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7549309 |
| Age: |
postnatal week 10 |
| Image: |
1 |
|
| Specimen Label: |
Spleen |
| Detected: |
false |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7543804 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2023-11-20 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3511228 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7549309 |
| Age: |
postnatal week 10 |
| Image: |
1 |
|
| Specimen Label: |
Fat |
| Detected: |
false |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7543804 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2023-11-20 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1689428 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7549309 |
| Age: |
postnatal week 10 |
| Image: |
1 |
|
| Specimen Label: |
Brain |
| Detected: |
false |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7543804 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2023-11-20 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1914328 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7549309 |
| Age: |
postnatal week 10 |
| Image: |
1 |
|
| Specimen Label: |
Femur |
| Detected: |
false |
| Specimen Num: |
8 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7543804 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2023-11-20 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1768128 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7549309 |
| Age: |
postnatal week 10 |
| Image: |
1 |
|
| Specimen Label: |
Calvaria |
| Detected: |
false |
| Specimen Num: |
9 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7595875 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2024-02-21 |
| Strength: |
Not Specified |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1619428 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7595898 |
| Age: |
postnatal day 21 |
| Image: |
1 |
|
| Specimen Label: |
Car9 |
|
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7595875 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2024-02-21 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1689428 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7595941 |
| Age: |
postnatal day 21 |
| Image: |
1 |
|
| Specimen Label: |
Car9 |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7595875 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2024-02-21 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1737328 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7595942 |
| Age: |
postnatal day 21 |
| Image: |
1 |
|
| Specimen Label: |
Car9 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7595875 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2024-02-21 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1684628 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7595943 |
| Age: |
postnatal day 21 |
| Image: |
1 |
|
| Specimen Label: |
Car9 |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7595875 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2024-02-21 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3185728 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7595944 |
| Age: |
postnatal day 8 |
| Image: |
1 |
|
| Specimen Label: |
Car9 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7595875 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2024-02-22 |
| Strength: |
Not Specified |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1619423 |
|
| Stage: |
TS23 |
| Assay Id: |
MGI:7596069 |
| Age: |
embryonic day 15.5 |
| Image: |
1 |
|
| Specimen Label: |
E15.5 |
|
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7595875 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2024-02-22 |
| Strength: |
Not Specified |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1619427 |
|
| Stage: |
TS27 |
| Assay Id: |
MGI:7596069 |
| Age: |
postnatal day 0 |
| Image: |
1 |
|
| Specimen Label: |
P0 |
|
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7595875 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2024-02-22 |
| Strength: |
Not Specified |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1619428 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7596069 |
| Age: |
postnatal day 5 |
| Image: |
1 |
|
| Specimen Label: |
P5 |
|
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7595875 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2024-02-22 |
| Strength: |
Not Specified |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1619428 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7596069 |
| Age: |
postnatal day 21 |
| Image: |
1 |
|
| Specimen Label: |
P21 |
|
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3706892 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2007-05-03 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1737319 |
|
| Stage: |
TS19 |
| Assay Id: |
MGI:3706895 |
| Age: |
embryonic day 11.5 |
|
|
| Specimen Label: |
Table 1 |
| Detected: |
false |
| Specimen Num: |
13 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3706892 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2007-05-03 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1737320 |
| Pattern: |
Not Specified |
| Stage: |
TS20 |
| Assay Id: |
MGI:3706895 |
| Age: |
embryonic day 12.5 |
|
|
| Specimen Label: |
Table 1 |
| Detected: |
true |
| Specimen Num: |
14 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3706892 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2007-05-03 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1737321 |
| Pattern: |
Not Specified |
| Stage: |
TS21 |
| Assay Id: |
MGI:3706895 |
| Age: |
embryonic day 13.5 |
|
|
| Specimen Label: |
Table 1 |
| Detected: |
true |
| Specimen Num: |
15 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3706892 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2007-05-03 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1733119 |
| Pattern: |
Not Specified |
| Stage: |
TS19 |
| Assay Id: |
MGI:3706895 |
| Age: |
embryonic day 11.5 |
|
|
| Specimen Label: |
Table 1 |
| Detected: |
true |
| Specimen Num: |
13 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3706892 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2007-05-03 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1733120 |
| Pattern: |
Not Specified |
| Stage: |
TS20 |
| Assay Id: |
MGI:3706895 |
| Age: |
embryonic day 12.5 |
|
|
| Specimen Label: |
Table 1 |
| Detected: |
true |
| Specimen Num: |
14 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3706892 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2007-05-03 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1733121 |
| Pattern: |
Not Specified |
| Stage: |
TS21 |
| Assay Id: |
MGI:3706895 |
| Age: |
embryonic day 13.5 |
|
|
| Specimen Label: |
Table 1 |
| Detected: |
true |
| Specimen Num: |
15 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3706892 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2007-05-03 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1672820 |
| Pattern: |
Not Specified |
| Stage: |
TS20 |
| Assay Id: |
MGI:3706895 |
| Age: |
embryonic day 12.5 |
|
|
| Specimen Label: |
Table 1 |
| Detected: |
true |
| Specimen Num: |
14 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3706892 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2007-05-03 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1672821 |
| Pattern: |
Not Specified |
| Stage: |
TS21 |
| Assay Id: |
MGI:3706895 |
| Age: |
embryonic day 13.5 |
|
|
| Specimen Label: |
Table 1 |
| Detected: |
true |
| Specimen Num: |
15 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3706892 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2007-05-03 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1672828 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:3706895 |
| Age: |
postnatal adult |
|
|
| Specimen Label: |
not shown |
| Detected: |
false |
| Specimen Num: |
12 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3706892 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2007-05-03 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1610528 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:3706895 |
| Age: |
postnatal adult |
|
|
| Specimen Label: |
not shown |
| Detected: |
false |
| Specimen Num: |
12 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3706892 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2007-05-03 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1603911 |
|
| Stage: |
TS11 |
| Assay Id: |
MGI:3706895 |
| Age: |
embryonic day 7.5 |
| Image: |
1A |
|
| Specimen Label: |
1A |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3706892 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2007-05-03 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1684620 |
| Pattern: |
Non-Uniform |
| Stage: |
TS20 |
| Assay Id: |
MGI:3706895 |
| Age: |
embryonic day 12.5 |
| Image: |
5C |
| Note: |
Signal was detected in scattered cells. |
| Specimen Label: |
5C |
| Detected: |
true |
| Specimen Num: |
11 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3706892 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2007-05-03 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1684619 |
| Pattern: |
Not Specified |
| Stage: |
TS19 |
| Assay Id: |
MGI:3706895 |
| Age: |
embryonic day 11.5 |
|
|
| Specimen Label: |
Table 1 |
| Detected: |
true |
| Specimen Num: |
13 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3706892 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2007-05-03 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1684620 |
| Pattern: |
Not Specified |
| Stage: |
TS20 |
| Assay Id: |
MGI:3706895 |
| Age: |
embryonic day 12.5 |
|
|
| Specimen Label: |
Table 1 |
| Detected: |
true |
| Specimen Num: |
14 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3706892 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2007-05-03 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1684621 |
| Pattern: |
Not Specified |
| Stage: |
TS21 |
| Assay Id: |
MGI:3706895 |
| Age: |
embryonic day 13.5 |
|
|
| Specimen Label: |
Table 1 |
| Detected: |
true |
| Specimen Num: |
15 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3706892 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2007-05-03 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1750320 |
| Pattern: |
Non-Uniform |
| Stage: |
TS20 |
| Assay Id: |
MGI:3706895 |
| Age: |
embryonic day 12.5 |
| Image: |
4A |
| Note: |
Expression was moderate in the pancreas, which was primarily seen in the basolateral plasma membrane and intracellular compartment of the epithelial cells. |
| Specimen Label: |
4A |
| Detected: |
true |
| Specimen Num: |
8 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3706892 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2007-05-03 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1750320 |
| Pattern: |
Not Specified |
| Stage: |
TS20 |
| Assay Id: |
MGI:3706895 |
| Age: |
embryonic day 12.5 |
|
|
| Specimen Label: |
Table 1 |
| Detected: |
true |
| Specimen Num: |
14 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3706892 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2007-05-03 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3274120 |
| Pattern: |
Not Specified |
| Stage: |
TS20 |
| Assay Id: |
MGI:3706895 |
| Age: |
embryonic day 12.5 |
| Image: |
2C |
|
| Specimen Label: |
2C |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3706892 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2007-05-03 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3287419 |
| Pattern: |
Not Specified |
| Stage: |
TS19 |
| Assay Id: |
MGI:3706895 |
| Age: |
embryonic day 11.5 |
|
|
| Specimen Label: |
Table 1 |
| Detected: |
true |
| Specimen Num: |
13 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3706892 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2007-05-03 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3287420 |
| Pattern: |
Not Specified |
| Stage: |
TS20 |
| Assay Id: |
MGI:3706895 |
| Age: |
embryonic day 12.5 |
|
|
| Specimen Label: |
Table 1 |
| Detected: |
true |
| Specimen Num: |
14 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3706892 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2007-05-03 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3287421 |
| Pattern: |
Not Specified |
| Stage: |
TS21 |
| Assay Id: |
MGI:3706895 |
| Age: |
embryonic day 13.5 |
|
|
| Specimen Label: |
Table 1 |
| Detected: |
true |
| Specimen Num: |
15 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3706892 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2007-05-03 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1679720 |
| Pattern: |
Not Specified |
| Stage: |
TS20 |
| Assay Id: |
MGI:3706895 |
| Age: |
embryonic day 12.5 |
| Image: |
2B |
|
| Specimen Label: |
2B |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3706892 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2007-05-03 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1764620 |
| Pattern: |
Regionally restricted |
| Stage: |
TS20 |
| Assay Id: |
MGI:3706895 |
| Age: |
embryonic day 12.5 |
| Image: |
3A |
| Note: |
Expression was weak in the ductal epithelium. |
| Specimen Label: |
3A |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|