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Search results 1 to 100 out of 5505 for Cdh1

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Type Details Score
Gene
999 | CDH1
Type: gene
Organism: human
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Gene
282637 | CDH1
Type: gene
Organism: cattle
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Gene
415860 | CDH1
Type: gene
Organism: chicken
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Gene
114424 | cdh1
Type: gene
Organism: zebrafish
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Gene
704387 | CDH1
Type: gene
Organism: macaque, rhesus
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Gene
779546 | cdh1
Type: gene
Organism: frog, western clawed
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Gene
83502 | Cdh1
Type: gene
Organism: rat
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Gene
442858 | CDH1
Type: gene
Organism: dog, domestic
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Gene
468009 | CDH1
Type: gene
Organism: chimpanzee
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Protein Domain
IPR030049 | CDH1
Type: Family
Description: E-cadherin (epithelial-cadherin), also known as cadherin-1 (CADH1), is a calcium-dependent adherens junction protein that forms homophilic intercellular contacts in epithelial cells []. It is essential for embryonic development in mice []. It cooperates with N-cadherin during lensdevelopment [].
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Protein Coding Gene
MGI:88354 | Cdh1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
8058792 | J:19904
First Author: Larue L
Year: 1994
Journal: Proc Natl Acad Sci U S A
Title: E-cadherin null mutant embryos fail to form a trophectoderm epithelium.
Volume: 91
Issue: 17
Pages: 8263-7
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Publication
18996109 | J:145191
First Author: Pontoriero GF
Year: 2009
Journal: Dev Biol
Title: Co-operative roles for E-cadherin and N-cadherin during lens vesicle separation and lens epithelial cell survival.
Volume: 326
Issue: 2
Pages: 403-17
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GXD Expression
GXD Expression
 
Probe: MGI:3821059
Assay Type: RNA in situ
Annotation Date: 2009-01-15
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3564522
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3825677
Age: embryonic day 14.5
Image: Additional file 4 Cdh1
Specimen Label: Additional file 4 Cdh1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5775351
Assay Type: Immunohistochemistry
Annotation Date: 2023-01-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760020
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:7414383
Age: embryonic day 12.5
Image: 1c E12.5 CDH1
Specimen Label: 1c E12.5 CDH1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5775351
Assay Type: Immunohistochemistry
Annotation Date: 2023-01-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760021
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7414383
Age: embryonic day 13.5
Image: 1c E13.5 CDH1
Specimen Label: 1c E13.5 CDH1
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:5775351
Assay Type: Immunohistochemistry
Annotation Date: 2023-01-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7414383
Age: embryonic day 14.5
Image: 1c E14.5 CDH1
Note: Areas of expression include the outer compartment of the developing organ of Corti.
Specimen Label: 1c E14.5 CDH1
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:5775351
Assay Type: Immunohistochemistry
Annotation Date: 2023-01-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:7414383
Age: embryonic day 15.5
Image: 1c E15.5 CDH1
Note: Areas of expression include the outer compartment of the developing organ of Corti.
Specimen Label: 1c E15.5 CDH1
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:5775351
Assay Type: Immunohistochemistry
Annotation Date: 2023-01-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1906126
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:7414383
Age: embryonic day 18.5
Image: 1c E18.5 CDH1
Note: Areas of expression include the outer compartment.
Specimen Label: 1c E18.5 CDH1
Detected: true
Specimen Num: 5
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Protein
P09803
Organism: Mus musculus/domesticus
Length: 884  
Fragment?: false
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Protein
Q4KML8
Organism: Mus musculus/domesticus
Length: 884  
Fragment?: false
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Protein
A0A0R4IZW5
Organism: Mus musculus/domesticus
Length: 884  
Fragment?: false
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Publication
25079037 | -
 
First Author: Chen A
Year: 2014
Journal: BMC Cancer
Title: E-cadherin loss alters cytoskeletal organization and adhesion in non-malignant breast cells but is insufficient to induce an epithelial-mesenchymal transition.
Volume: 14
Pages: 552
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GXD Expression
GXD Expression
Probe: MGI:7414254
Assay Type: Immunohistochemistry
Annotation Date: 2023-01-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760020
Pattern: Widespread
Stage: TS20
Assay Id: MGI:7414373
Age: embryonic day 12.5
Image: 1c E12.5 CDH1
Note: Expression is seen in the prosensory epithelium in the floor of the cochlear duct.
Specimen Label: 1c E12.5 CDH1
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
Probe: MGI:7414254
Assay Type: Immunohistochemistry
Annotation Date: 2023-01-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760021
Pattern: Widespread
Stage: TS21
Assay Id: MGI:7414373
Age: embryonic day 13.5
Image: 1c E13.5 CDH1
Note: Expression is seen in the prosensory epithelium in the floor of the cochlear duct.
Specimen Label: 1c E13.5 CDH1
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
Probe: MGI:7414254
Assay Type: Immunohistochemistry
Annotation Date: 2023-01-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760022
Pattern: Non-Uniform
Stage: TS22
Assay Id: MGI:7414373
Age: embryonic day 14.5
Image: 1c E14.5 CDH1
Note: Expression is seen in the prosensory epithelium. Expression is strongly upregulated in the inner (medial) region of the developing organ of Corti; it is excluded from the outer (lateral) region.
Specimen Label: 1c E14.5 CDH1
Detected: true
Specimen Num: 13
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GXD Expression
GXD Expression
Probe: MGI:7414254
Assay Type: Immunohistochemistry
Annotation Date: 2023-01-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760023
Pattern: Non-Uniform
Stage: TS23
Assay Id: MGI:7414373
Age: embryonic day 15.5
Image: 1c E15.5 CDH1
Note: Expression is seen in the prosensory epithelium. Expression is strongly upregulated in the inner (medial) region of the developing organ of Corti; it is excluded from the outer (lateral) region.
Specimen Label: 1c E15.5 CDH1
Detected: true
Specimen Num: 14
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GXD Expression
GXD Expression
Probe: MGI:7414254
Assay Type: Immunohistochemistry
Annotation Date: 2023-01-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3549226
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7414373
Age: embryonic day 18.5
Image: 1c E18.5 CDH1
Note: Expression is weaker than in the organ of Corti.
Specimen Label: 1c E18.5 CDH1
Detected: true
Specimen Num: 15
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GXD Expression
GXD Expression
Probe: MGI:7414254
Assay Type: Immunohistochemistry
Annotation Date: 2023-01-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1906126
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:7414373
Age: embryonic day 18.5
Image: 1c E18.5 CDH1
Note: Expression is strongly upregulated in the inner (medial) region of the developing organ of Corti; it is excluded from the outer (lateral) region.
Specimen Label: 1c E18.5 CDH1
Detected: true
Specimen Num: 15
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GXD Expression
GXD Expression
Probe: MGI:7414254
Assay Type: Immunohistochemistry
Annotation Date: 2023-01-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3538426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7414373
Age: embryonic day 18.5
Image: 1c E18.5 CDH1
Note: Expression is weaker than in the organ of Corti.
Specimen Label: 1c E18.5 CDH1
Detected: true
Specimen Num: 15
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Publication
22152476 | J:317065
First Author: Wan L
Year: 2011
Journal: Mol Cell
Title: Cdh1 regulates osteoblast function through an APC/C-independent modulation of Smurf1.
Volume: 44
Issue: 5
Pages: 721-33
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Publication
20652949 | J:163273
First Author: Stemmler MP
Year: 2010
Journal: Dev Dyn
Title: A Cdh1HA knock-in allele rescues the Cdh1-/- phenotype but shows essential Cdh1 function during placentation.
Volume: 239
Issue: 9
Pages: 2330-44
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Publication
17035642 | J:117360
First Author: Tokuda M
Year: 2007
Journal: Biol Reprod
Title: CDH1 is a specific marker for undifferentiated spermatogonia in mouse testes.
Volume: 76
Issue: 1
Pages: 130-41
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Publication
33211830 | J:298844
 
First Author: Pascal LE
Year: 2021
Journal: Endocrinology
Title: Prostate-Specific Deletion of Cdh1 Induces Murine Prostatic Inflammation and Bladder Overactivity.
Volume: 162
Issue: 1
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HT Experiment
E-GEOD-54234 | CDH1 knockout in mice
Series Id: GSE54234
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
30332649 | J:270695
First Author: An Y
Year: 2018
Journal: Cell Rep
Title: Cdh1 and Pik3ca Mutations Cooperate to Induce Immune-Related Invasive Lobular Carcinoma of the Breast.
Volume: 25
Issue: 3
Pages: 702-714.e6
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Publication
31964702 | J:287966
 
First Author: Wang Y
Year: 2020
Journal: J Cell Sci
Title: CENP-T regulates both the G2/M transition and anaphase entry by acting through CDH1 in meiotic oocytes.
Volume: 133
Issue: 3
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Publication
24301385 | J:206141
 
First Author: Eguren M
Year: 2013
Journal: Nat Commun
Title: The APC/C cofactor Cdh1 prevents replicative stress and p53-dependent cell death in neural progenitors.
Volume: 4
Pages: 2880
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Publication
23740945 | J:202051
First Author: Lindberg ME
Year: 2013
Journal: Biol Reprod
Title: Loss of CDH1 and Pten accelerates cellular invasiveness and angiogenesis in the mouse uterus.
Volume: 89
Issue: 1
Pages: 8
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Publication
22378759 | J:185830
First Author: Reardon SN
Year: 2012
Journal: Biol Reprod
Title: CDH1 is essential for endometrial differentiation, gland development, and adult function in the mouse uterus.
Volume: 86
Issue: 5
Pages: 141, 1-10
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Publication
35729193 | J:326127
First Author: Cuadrado M
Year: 2022
Journal: Sci Rep
Title: Efficient terminal erythroid differentiation requires the APC/C cofactor Cdh1 to limit replicative stress in erythroblasts.
Volume: 12
Issue: 1
Pages: 10489
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Publication
20530197 | J:162785
First Author: Naoe H
Year: 2010
Journal: Mol Cell Biol
Title: The anaphase-promoting complex/cyclosome activator Cdh1 modulates Rho GTPase by targeting p190 RhoGAP for degradation.
Volume: 30
Issue: 16
Pages: 3994-4005
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Publication
24998851 | J:221256
First Author: Stodden GR
Year: 2015
Journal: Oncogene
Title: Loss of Cdh1 and Trp53 in the uterus induces chronic inflammation with modification of tumor microenvironment.
Volume: 34
Issue: 19
Pages: 2471-82
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Publication
28065642 | J:316682
First Author: An J
Year: 2017
Journal: Stem Cell Reports
Title: Mesenchymal to Epithelial Transition Mediated by CDH1 Promotes Spontaneous Reprogramming of Male Germline Stem Cells to Pluripotency.
Volume: 8
Issue: 2
Pages: 446-459
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Publication
31930396 | J:298073
First Author: Shi M
Year: 2020
Journal: Biol Reprod
Title: Inactivation of TRP53, PTEN, RB1, and/or CDH1 in the ovarian surface epithelium induces ovarian cancer transformation and metastasis.
Volume: 102
Issue: 5
Pages: 1055-1064
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Publication
30168144 | J:273794
First Author: Kinoshita H
Year: 2019
Journal: J Pathol
Title: Three types of metaplasia model through Kras activation, Pten deletion, or Cdh1 deletion in the gastric epithelium.
Volume: 247
Issue: 1
Pages: 35-47
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Publication
19160489 | J:138545
First Author: Li M
Year: 2008
Journal: Nat Cell Biol
Title: The adaptor protein of the anaphase promoting complex Cdh1 is essential in maintaining replicative lifespan and in learning and memory.
Volume: 10
Issue: 9
Pages: 1083-9
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GXD Expression
GXD Expression
   
Probe: MGI:6169465
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6189933
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Cdh1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6169465
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6189933
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Cdh1
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6169465
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6189933
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Cdh1
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6169465
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6189933
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Cdh1
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6169465
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189933
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Cdh1
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6169465
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189933
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Cdh1
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6169465
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189933
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Cdh1
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
Probe: MGI:1935063
Assay Type: Immunohistochemistry
Annotation Date: 2001-06-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1698121
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:2135569
Age: embryonic day 13.5
Image: 3F/G
Note: Two Cdh1 positive columns of expression are detected in the mesencephalic roof plate.
Specimen Label: 3F/G
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
Probe: MGI:1935187
Assay Type: Immunohistochemistry
Annotation Date: 2024-04-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3286024
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:7623789
Age: embryonic day 16.5
Image: 4D
Note: Cdh1 immunolabeled epithelial cells displayed relatively normal cell rounding in the Cyp26b1-/- lungs.
Specimen Label: 4D
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:1935063
Assay Type: Immunohistochemistry
Annotation Date: 2001-06-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1707120
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:2135569
Age: embryonic day 12.5
Image: 3C/D/E
Note: Cdh1 positive fibers extend to the marginal zone and migrated upwards to the ventral midline.
Specimen Label: 3C/D/E
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:1339624
Assay Type: Immunohistochemistry
Annotation Date: 2022-02-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160403
Pattern: Regionally restricted
Stage: TS03
Assay Id: MGI:6867049
Age: embryonic day 3.0
Note: Double staining revealed co-localization of Tjp2 and Cdh1 in the apicolateral junctional complex.
Specimen Label: 4A
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:6194264
Assay Type: Western blot
Annotation Date: 2022-08-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Stage: TS28
Assay Id: MGI:7328801
Age: postnatal day 12
Specimen Label: Cdh1 cKO
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:1339624
Assay Type: Immunohistochemistry
Annotation Date: 2022-02-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360354
Pattern: Regionally restricted
Stage: TS04
Assay Id: MGI:6867049
Age: embryonic day 3.5
Note: Cdh1 staining was localized in the apicolateral junctional complex, but in early blastocysts Tjp2 is apical to and distinct from Cdh1.
Specimen Label: 4B
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:1935187
Assay Type: Immunohistochemistry
Annotation Date: 2024-04-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3286025
Pattern: Regionally restricted
Stage: TS25
Assay Id: MGI:7623789
Age: embryonic day 17.5
Image: 4E
Note: Cdh1 immunolabeled epithelial cells had a flattened, or squamous, morphology for AT1 cells and a rounded morphology for AT2 cells by E17.5.
Specimen Label: 4E
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
Probe: MGI:1935187
Assay Type: Immunohistochemistry
Annotation Date: 2024-04-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3286025
Pattern: Regionally restricted
Stage: TS25
Assay Id: MGI:7623789
Age: embryonic day 17.5
Image: 4F
Note: Cdh1 immunolabeled epithelial cells displayed relatively normal cell rounding in the Cyp26b1-/- lungs; however, the transition to flattened epithelium was delayed.
Specimen Label: 4F
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:6448438
Assay Type: Immunohistochemistry
Annotation Date: 2020-08-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:6448447
Age: embryonic day 8.5
Note: Large masses of progenitor cells accumulated beneath the primitive streak expressing high levels of Cdh1 in a domain much larger than is normally found at the streak, and at greater levels than the overlying ectoderm.
Specimen Label: 2H
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:6448438
Assay Type: Immunohistochemistry
Annotation Date: 2020-08-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:6448447
Age: embryonic day 8.5
Note: Large masses of progenitor cells accumulated beneath the primitive streak expressing high levels of Cdh1 in a domain much larger than is normally found at the streak, and at greater levels than the overlying ectoderm.
Specimen Label: 2I
Detected: true
Specimen Num: 5
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Publication
31420536 | J:279397
First Author: Han T
Year: 2019
Journal: Nat Commun
Title: Interplay between c-Src and the APC/C co-activator Cdh1 regulates mammary tumorigenesis.
Volume: 10
Issue: 1
Pages: 3716
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Publication
27126000 | J:302804
First Author: Shao R
Year: 2016
Journal: Cell Res
Title: Cdh1 regulates craniofacial development via APC-dependent ubiquitination and activation of Goosecoid.
Volume: 26
Issue: 6
Pages: 699-712
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Publication
23206702 | J:193869
First Author: Naoe H
Year: 2013
Journal: Biochem Biophys Res Commun
Title: The APC/C activator Cdh1 regulates the G2/M transition during differentiation of placental trophoblast stem cells.
Volume: 430
Issue: 2
Pages: 757-62
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Publication
24100295 | J:201983
First Author: Listovsky T
Year: 2013
Journal: J Cell Biol
Title: Sequestration of CDH1 by MAD2L2 prevents premature APC/C activation prior to anaphase onset.
Volume: 203
Issue: 1
Pages: 87-100
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Publication
14716021 | J:90373
First Author: Konishi Y
Year: 2004
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