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Search results 1 to 100 out of 110 for Cul9

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0.076s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Domain
Type: Family
Description: Cullin-9, also known as PARC, is a core component of a Cul9-RING ubiquitin-protein ligase complex, a complex that mediates ubiquitination and subsequent degradation of survivin (BIRC5), an inhibitor of apoptosis protein. It is a critical downstream effector of the 3M complex (consisting of CUL7, OBSL1 and CCDC8) in the maintenance of microtubules and genome integrity []. It also regulates the subcellular localisation of p53/TP53 and subsequent function [, ].
Publication
First Author: Li Z
Year: 2014
Journal: Mol Cell
Title: CUL9 mediates the functions of the 3M complex and ubiquitylates survivin to maintain genome integrity.
Volume: 54
Issue: 5
Pages: 805-19
Publication
First Author: Skaar JR
Year: 2007
Journal: Cancer Res
Title: PARC and CUL7 form atypical cullin RING ligase complexes.
Volume: 67
Issue: 5
Pages: 2006-14
Protein
Organism: Mus musculus/domesticus
Length: 1865  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 2520  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 2530  
Fragment?: false
Publication
First Author: Nikolaev AY
Year: 2003
Journal: Cell
Title: Parc: a cytoplasmic anchor for p53.
Volume: 112
Issue: 1
Pages: 29-40
Publication
First Author: Pei XH
Year: 2011
Journal: Cancer Res
Title: Cytoplasmic CUL9/PARC ubiquitin ligase is a tumor suppressor and promotes p53-dependent apoptosis.
Volume: 71
Issue: 8
Pages: 2969-77
Publication
First Author: Hollville E
Year: 2020
Journal: Sci Rep
Title: Characterization of a Cul9-Parkin double knockout mouse model for Parkinson's disease.
Volume: 10
Issue: 1
Pages: 16886
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression      
Probe: MGI:5295244
Assay Type: RT-PCR
Annotation Date: 2011-11-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603917
Stage: TS17
Assay Id: MGI:5295627
Age: embryonic day 10.5
Specimen Label: None
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5897994
Assay Type: Western blot
Annotation Date: 2017-05-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603921
Stage: TS21
Assay Id: MGI:5898016
Age: embryonic day 13.5
Specimen Label: Cul9+/+ p53+/+
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5897994
Assay Type: Western blot
Annotation Date: 2017-05-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603921
Stage: TS21
Assay Id: MGI:5898016
Age: embryonic day 13.5
Specimen Label: Cul9-/- p53-/-
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:5897994
Assay Type: Western blot
Annotation Date: 2017-05-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603921
Stage: TS21
Assay Id: MGI:5898016
Age: embryonic day 13.5
Specimen Label: Cul9-/- p53+/+
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:5897994
Assay Type: Western blot
Annotation Date: 2017-05-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603921
Stage: TS21
Assay Id: MGI:5898016
Age: embryonic day 13.5
Specimen Label: Cul9+/+ p53-/-
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:5897994
Assay Type: Western blot
Annotation Date: 2017-05-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:5898017
Age: embryonic day 15.5
Specimen Label: E15.5 wt
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5897994
Assay Type: Western blot
Annotation Date: 2017-05-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:5898017
Age: embryonic day 15.5
Specimen Label: E15.5 p53-/-
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:5897994
Assay Type: Western blot
Annotation Date: 2017-05-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603925
Stage: TS25
Assay Id: MGI:5898017
Age: embryonic day 17.5
Specimen Label: E17.5 wt
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:5897994
Assay Type: Western blot
Annotation Date: 2017-05-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603925
Stage: TS25
Assay Id: MGI:5898017
Age: embryonic day 17.5
Specimen Label: E17.5 p53-/-
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:5897994
Assay Type: Western blot
Annotation Date: 2017-05-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5898018
Age: postnatal week 7-8
Specimen Label: WT Brain
Detected: true
Specimen Num: 1
GXD Expression        
Probe: MGI:5897994
Assay Type: Western blot
Annotation Date: 2017-05-25
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:5898018
Age: postnatal week 7-8
Specimen Label: WT Thymus
Specimen Num: 2
GXD Expression        
Probe: MGI:5897994
Assay Type: Western blot
Annotation Date: 2017-05-25
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:5898018
Age: postnatal week 7-8
Specimen Label: WT Spleen
Specimen Num: 3
GXD Expression      
Probe: MGI:5897994
Assay Type: Western blot
Annotation Date: 2017-05-25
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5898018
Age: postnatal week 7-8
Specimen Label: WT Testis
Detected: true
Specimen Num: 4
GXD Expression        
Probe: MGI:5897994
Assay Type: Western blot
Annotation Date: 2017-05-25
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:3271528
Stage: TS28
Assay Id: MGI:5898018
Age: postnatal week 7-8
Specimen Label: WT Muscle
Specimen Num: 5
GXD Expression      
Probe: MGI:5897994
Assay Type: Western blot
Annotation Date: 2017-05-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5898018
Age: postnatal week 7-8
Specimen Label: p53-/- Brain
Detected: true
Specimen Num: 6
GXD Expression        
Probe: MGI:5897994
Assay Type: Western blot
Annotation Date: 2017-05-25
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:5898018
Age: postnatal week 7-8
Specimen Label: p53-/- Thymus
Specimen Num: 7
GXD Expression        
Probe: MGI:5897994
Assay Type: Western blot
Annotation Date: 2017-05-25
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:5898018
Age: postnatal week 7-8
Specimen Label: p53-/- Spleen
Specimen Num: 8
GXD Expression      
Probe: MGI:5897994
Assay Type: Western blot
Annotation Date: 2017-05-25
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5898018
Age: postnatal week 7-8
Specimen Label: p53-/- Testis
Detected: true
Specimen Num: 9
GXD Expression        
Probe: MGI:5897994
Assay Type: Western blot
Annotation Date: 2017-05-25
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:3271528
Stage: TS28
Assay Id: MGI:5898018
Age: postnatal week 7-8
Specimen Label: p53-/- Muscle
Specimen Num: 10
GXD Expression      
Probe: MGI:5897994
Assay Type: Western blot
Annotation Date: 2017-05-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5898018
Age: postnatal week 7-8
Specimen Label: Cul9/- Brain
Detected: false
Specimen Num: 11
GXD Expression      
Probe: MGI:5897994
Assay Type: Western blot
Annotation Date: 2017-05-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:5898018
Age: postnatal week 7-8
Specimen Label: Cul9-/- Thymus
Detected: false
Specimen Num: 12
GXD Expression      
Probe: MGI:5897994
Assay Type: Western blot
Annotation Date: 2017-05-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:5898018
Age: postnatal week 7-8
Specimen Label: Cul9-/- Spleen
Detected: false
Specimen Num: 13
GXD Expression      
Probe: MGI:5897994
Assay Type: Western blot
Annotation Date: 2017-05-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5898018
Age: postnatal week 7-8
Specimen Label: Cul9-/- Testis
Detected: false
Specimen Num: 14
GXD Expression      
Probe: MGI:5897994
Assay Type: Western blot
Annotation Date: 2017-05-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3271528
Stage: TS28
Assay Id: MGI:5898018
Age: postnatal week 7-8
Specimen Label: Cul9-/- Muscle
Detected: false
Specimen Num: 15
GXD Expression      
Probe: MGI:3584961
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1716822
Stage: TS22
Assay Id: MGI:3586290
Age: embryonic day 14.0
Specimen Label: E14
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:3584961
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1859224
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:3586290
Age: embryonic day 16.0
Note: Expression was detected in the outer neuroblastic layer.
Specimen Label: E16
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3584961
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1915726
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:3586290
Age: embryonic day 18.0
Note: Expression was detected in the outer neuroblastic layer.
Specimen Label: E18
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:3584961
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1915727
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3586290
Age: postnatal day 0-1
Note: Expression was detected in the outer neuroblastic layer.
Specimen Label: P0/1
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:3584961
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1915727
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3586290
Age: postnatal day 2-3
Note: Expression was detected in the outer neuroblastic layer.
Specimen Label: P2/3
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:3584961
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1915728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3586290
Age: postnatal day 4-5
Note: Expression was detected in the outer neuroblastic layer.
Specimen Label: P4/5
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:3584961
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1915728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3586290
Age: postnatal day 6-7
Specimen Label: P6/7
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:3584961
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1915728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3586290
Age: postnatal day 8-10
Specimen Label: P8/10
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:3584961
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1915528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3586290
Age: postnatal day 8-10
Specimen Label: P8/10
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:3584961
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Male
Emaps: EMAPS:1915728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3586290
Age: postnatal adult
Specimen Label: Adult
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:3584961
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Male
Emaps: EMAPS:1915528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3586290
Age: postnatal adult
Specimen Label: Adult
Detected: true
Specimen Num: 9
Publication
First Author: Dai X
Year: 2016
Journal: Biochim Biophys Acta
Title: Cullin9 protects mouse eggs from aneuploidy by controlling microtubule dynamics via Survivin.
Volume: 1863
Issue: 12
Pages: 2934-2941
Publication
First Author: Skaar JR
Year: 2005
Journal: Mol Cell Biol
Title: Dimerization of CUL7 and PARC is not required for all CUL7 functions and mouse development.
Volume: 25
Issue: 13
Pages: 5579-89
Publication
First Author: Gama V
Year: 2014
Journal: Sci Signal
Title: The E3 ligase PARC mediates the degradation of cytosolic cytochrome c to promote survival in neurons and cancer cells.
Volume: 7
Issue: 334
Pages: ra67
Publication
First Author: Barkić M
Year: 2009
Journal: Mol Cell Biol
Title: The p53 tumor suppressor causes congenital malformations in Rpl24-deficient mice and promotes their survival.
Volume: 29
Issue: 10
Pages: 2489-504
Publication
First Author: Okazaki N
Year: 2003
Journal: DNA Res
Title: Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.
Volume: 10
Issue: 1
Pages: 35-48
Publication
First Author: Blackshaw S
Year: 2004
Journal: PLoS Biol
Title: Genomic analysis of mouse retinal development.
Volume: 2
Issue: 9
Pages: E247
Publication      
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
Publication      
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes