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Search results 1 to 100 out of 381 for Cyld

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Type Details Score
Gene
1540 | CYLD
Type: gene
Organism: human
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Gene
465165 | CYLD
Type: gene
Organism: chimpanzee
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Gene
536421 | CYLD
Type: gene
Organism: cattle
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Gene
415725 | CYLD
Type: gene
Organism: chicken
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Gene
695652 | CYLD
Type: gene
Organism: macaque, rhesus
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Gene
100144739 | cyld
Type: gene
Organism: frog, western clawed
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Gene
312937 | Cyld
Type: gene
Organism: rat
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Gene
611649 | CYLD
Type: gene
Organism: dog, domestic
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Gene
556823 | cyld
Type: gene
Organism: zebrafish
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Protein Coding Gene
MGI:1921506 | Cyld
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
17548520 | J:125855
First Author: Reiley WW
Year: 2007
Journal: J Exp Med
Title: Deubiquitinating enzyme CYLD negatively regulates the ubiquitin-dependent kinase Tak1 and prevents abnormal T cell responses.
Volume: 204
Issue: 6
Pages: 1475-85
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Publication
25134987 | J:215909
 
First Author: Eguether T
Year: 2014
Journal: Nat Commun
Title: The deubiquitinating enzyme CYLD controls apical docking of basal bodies in ciliated epithelial cells.
Volume: 5
Pages: 4585
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Publication
16713561 | J:108769
First Author: Massoumi R
Year: 2006
Journal: Cell
Title: Cyld inhibits tumor cell proliferation by blocking Bcl-3-dependent NF-kappaB signaling.
Volume: 125
Issue: 4
Pages: 665-77
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Publication
33934395 | J:335101
First Author: Yang S
Year: 2021
Journal: J Clin Lab Anal
Title: CYLD deficiency causes auditory neuropathy due to reduced neurite outgrowth.
Volume: 35
Issue: 6
Pages: e23783
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Publication
36878342 | J:335030
 
First Author: Chen SY
Year: 2023
Journal: Brain Res
Title: Deubiquitinase CYLD regulates excitatory synaptic transmission and short-term plasticity in the hippocampus.
Volume: 1806
Pages: 148313
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Publication
25342559 | J:226872
First Author: Yang Y
Year: 2014
Journal: Cell Res
Title: CYLD mediates ciliogenesis in multiple organs by deubiquitinating Cep70 and inactivating HDAC6.
Volume: 24
Issue: 11
Pages: 1342-53
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Publication
24104553 | J:206077
First Author: Pannem RR
Year: 2014
Journal: Carcinogenesis
Title: CYLD controls c-MYC expression through the JNK-dependent signaling pathway in hepatocellular carcinoma.
Volume: 35
Issue: 2
Pages: 461-8
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Publication
24469800 | J:206660
First Author: Yang Y
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: CYLD regulates spindle orientation by stabilizing astral microtubules and promoting dishevelled-NuMA-dynein/dynactin complex formation.
Volume: 111
Issue: 6
Pages: 2158-63
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Publication
23002441 | J:190622
First Author: Chu Y
Year: 2012
Journal: J Immunol
Title: A20 and CYLD do not share significant overlapping functions during B cell development and activation.
Volume: 189
Issue: 9
Pages: 4437-43
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Publication
17392286 | J:122705
First Author: Jin W
Year: 2007
Journal: J Biol Chem
Title: Deubiquitinating enzyme CYLD regulates the peripheral development and naive phenotype maintenance of B cells.
Volume: 282
Issue: 21
Pages: 15884-93
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Publication
27042826 | J:309405
First Author: Karatzas DN
Year: 2016
Journal: Cell Oncol (Dordr)
Title: Inactivation of CYLD in intestinal epithelial cells exacerbates colitis-associated colorectal carcinogenesis - a short report.
Volume: 39
Issue: 3
Pages: 287-93
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Publication
25493017 | J:335032
First Author: Urbanik T
Year: 2014
Journal: World J Gastroenterol
Title: CYLD deletion triggers nuclear factor-κB-signaling and increases cell death resistance in murine hepatocytes.
Volume: 20
Issue: 45
Pages: 17049-64
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Publication
36846565 | J:343364
 
First Author: Tan SY
Year: 2023
Journal: Front Mol Neurosci
Title: Neural mechanism underlies CYLD modulation of morphology and synaptic function of medium spiny neurons in dorsolateral striatum.
Volume: 16
Pages: 1107355
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Publication
21573132 | J:172429
First Author: Liang G
Year: 2011
Journal: PLoS One
Title: Serum response factor controls CYLD expression via MAPK signaling pathway.
Volume: 6
Issue: 5
Pages: e19613
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Publication
32424362 | J:306372
First Author: Mukherjee S
Year: 2020
Journal: Nat Immunol
Title: Deubiquitination of NLRP6 inflammasome by Cyld critically regulates intestinal inflammation.
Volume: 21
Issue: 6
Pages: 626-635
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Publication
28750888 | J:317314
First Author: Xie W
Year: 2017
Journal: J Genet Genomics
Title: The tumor suppressor CYLD controls epithelial morphogenesis and homeostasis by regulating mitotic spindle behavior and adherens junction assembly.
Volume: 44
Issue: 7
Pages: 343-353
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Publication
31591386 | J:335289
First Author: de Jel MM
Year: 2019
Journal: Oncogenesis
Title: Loss of CYLD accelerates melanoma development and progression in the Tg(Grm1) melanoma mouse model.
Volume: 8
Issue: 10
Pages: 56
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Publication
35293595 | J:335159
 
First Author: Schott M
Year: 2022
Journal: Int J Mol Med
Title: Impact of CYLD on chromatin structure and histone methylation in malignant melanoma.
Volume: 49
Issue: 5
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Publication
34602983 | J:312731
 
First Author: Li HD
Year: 2021
Journal: Front Cell Neurosci
Title: Deficiency of the CYLD Impairs Fear Memory of Mice and Disrupts Neuronal Activity and Synaptic Transmission in the Basolateral Amygdala.
Volume: 15
Pages: 740165
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Publication
22491319 | J:226141
 
First Author: Lim JH
Year: 2012
Journal: Nat Commun
Title: CYLD negatively regulates transforming growth factor-β-signalling via deubiquitinating Akt.
Volume: 3
Pages: 771
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Publication
19342479 | J:149355
First Author: Srokowski CC
Year: 2009
Journal: Blood
Title: Naturally occurring short splice variant of CYLD positively regulates dendritic cell function.
Volume: 113
Issue: 23
Pages: 5891-5
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Publication
32722292 | J:307221
 
First Author: Pseftogas A
Year: 2020
Journal: Cancers (Basel)
Title: The Tumor Suppressor CYLD Inhibits Mammary Epithelial to Mesenchymal Transition by the Coordinated Inhibition of YAP/TAZ and TGF Signaling.
Volume: 12
Issue: 8
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Publication
18382763 | J:136170
First Author: Jin W
Year: 2008
Journal: J Clin Invest
Title: Deubiquitinating enzyme CYLD negatively regulates RANK signaling and osteoclastogenesis in mice.
Volume: 118
Issue: 5
Pages: 1858-66
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Publication
23066153 | J:190708
First Author: Reissig S
Year: 2012
Journal: J Immunol
Title: The tumor suppressor CYLD controls the function of murine regulatory T cells.
Volume: 189
Issue: 10
Pages: 4770-6
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Publication
28751569 | J:269258
First Author: Yu B
Year: 2017
Journal: Arterioscler Thromb Vasc Biol
Title: CYLD Deubiquitinates Nicotinamide Adenine Dinucleotide Phosphate Oxidase 4 Contributing to Adventitial Remodeling.
Volume: 37
Issue: 9
Pages: 1698-1709
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Publication
23825949 | J:213378
First Author: Nishanth G
Year: 2013
Journal: PLoS Pathog
Title: CYLD enhances severe listeriosis by impairing IL-6/STAT3-dependent fibrin production.
Volume: 9
Issue: 6
Pages: e1003455
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Publication
21283724 | J:169567
First Author: Tsagaratou A
Year: 2011
Journal: PLoS One
Title: Truncation of the deubiquitinating domain of CYLD in myelomonocytic cells attenuates inflammatory responses.
Volume: 6
Issue: 1
Pages: e16397
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Publication
27264187 | J:238243
First Author: Legarda D
Year: 2016
Journal: Cell Rep
Title: CYLD Proteolysis Protects Macrophages from TNF-Mediated Auto-necroptosis Induced by LPS and Licensed by Type I IFN.
Volume: 15
Issue: 11
Pages: 2449-61
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Publication
24811579 | J:335033
First Author: Pannem RR
Year: 2014
Journal: Hepatology
Title: Cylindromatosis gene CYLD regulates hepatocyte growth factor expression in hepatic stellate cells through interaction with histone deacetylase 7.
Volume: 60
Issue: 3
Pages: 1066-81
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Publication
25675948 | J:229783
First Author: Wurm R
Year: 2015
Journal: Eur J Immunol
Title: Protective dendritic cell responses against listeriosis induced by the short form of the deubiquitinating enzyme CYLD are inhibited by full-length CYLD.
Volume: 45
Issue: 5
Pages: 1366-76
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Publication
25389768 | J:225158
First Author: Wang WY
Year: 2014
Journal: PLoS One
Title: CYLD negatively regulates nontypeable Haemophilus influenzae-induced IL-8 expression via phosphatase MKP-1-dependent inhibition of ERK.
Volume: 9
Issue: 11
Pages: e112516
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Publication
25935309 | J:225755
 
First Author: Wang H
Year: 2015
Journal: J Mol Cell Cardiol
Title: Deubiquitinating enzyme CYLD mediates pressure overload-induced cardiac maladaptive remodeling and dysfunction via downregulating Nrf2.
Volume: 84
Pages: 143-53
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Publication
20832754 | J:164199
First Author: Espinosa L
Year: 2010
Journal: Cancer Cell
Title: The Notch/Hes1 pathway sustains NF-κB activation through CYLD repression in T cell leukemia.
Volume: 18
Issue: 3
Pages: 268-81
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Publication
21931165 | J:178157
First Author: Zhao Y
Year: 2011
Journal: J Biol Chem
Title: The deubiquitinase CYLD targets Smad7 protein to regulate transforming growth factor β (TGF-β) signaling and the development of regulatory T cells.
Volume: 286
Issue: 47
Pages: 40520-30
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Publication
30315770 | J:286807
First Author: Tang Y
Year: 2019
Journal: Gastroenterology
Title: Alternative Splice Forms of CYLD Mediate Ubiquitination of SMAD7 to Prevent TGFB Signaling and Promote Colitis.
Volume: 156
Issue: 3
Pages: 692-707.e7
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Publication
19893491 | J:163064
First Author: Wickström SA
Year: 2010
Journal: EMBO J
Title: CYLD negatively regulates cell-cycle progression by inactivating HDAC6 and increasing the levels of acetylated tubulin.
Volume: 29
Issue: 1
Pages: 131-44
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Publication
31852310 | J:290134
First Author: Yu Q
Year: 2020
Journal: Artif Cells Nanomed Biotechnol
Title: CYLD expression in dendritic cells involved in the immunoregulation of pulmonary adenocarcinoma via NF-κB pathway.
Volume: 48
Issue: 1
Pages: 137-142
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Publication
36577382 | J:332434
First Author: Xie W
Year: 2022
Journal: Cell Rep
Title: CYLD deubiquitinates plakoglobin to promote Cx43 membrane targeting and gap junction assembly in the heart.
Volume: 41
Issue: 13
Pages: 111864
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Publication
31097224 | J:290717
First Author: Li L
Year: 2019
Journal: Biochem Biophys Res Commun
Title: CYLD deficiency exacerbates lipopolysaccharide (LPS)-induced pyroptosis in astrocytes of mice with sepsis.
Volume: 514
Issue: 4
Pages: 1066-1073
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Publication
34201751 | J:308809
 
First Author: Alameda JP
Year: 2021
Journal: Int J Mol Sci
Title: CYLD Inhibits the Development of Skin Squamous Cell Tumors in Immunocompetent Mice.
Volume: 22
Issue: 13
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Publication
32553594 | J:293688
 
First Author: Qi L
Year: 2020
Journal: J Mol Cell Cardiol
Title: CYLD exaggerates pressure overload-induced cardiomyopathy via suppressing autolysosome efflux in cardiomyocytes.
Volume: 145
Pages: 59-73
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Publication
26224629 | J:225580
First Author: Zhao Y
Year: 2015
Journal: J Biol Chem
Title: CYLD and the NEMO Zinc Finger Regulate Tumor Necrosis Factor Signaling and Early Embryogenesis.
Volume: 290
Issue: 36
Pages: 22076-84
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Publication
26719415 | J:229812
First Author: Lee BC
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Deubiquitinase CYLD acts as a negative regulator for bacterium NTHi-induced inflammation by suppressing K63-linked ubiquitination of MyD88.
Volume: 113
Issue: 2
Pages: E165-71
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Publication
27561390 | J:241614
 
First Author: Fernández-Majada V
Year: 2016
Journal: Nat Commun
Title: The tumour suppressor CYLD regulates the p53 DNA damage response.
Volume: 7
Pages: 12508
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Publication
22057290 | J:179005
First Author: Ahmed N
Year: 2011
Journal: Nat Immunol
Title: The E3 ligase Itch and deubiquitinase Cyld act together to regulate Tak1 and inflammation.
Volume: 12
Issue: 12
Pages: 1176-83
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Gene
102724907 | CYLD-AS1
Type: gene
Organism: human
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Gene
105371251 | CYLD-AS2
Type: gene
Organism: human
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Publication
17723219 | J:124327
First Author: Lim JH
Year: 2007
Journal: Immunity
Title: Tumor suppressor CYLD regulates acute lung injury in lethal Streptococcus pneumoniae infections.
Volume: 27
Issue: 2
Pages: 349-60
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Publication
16501569 | J:112392
First Author: Reiley WW
Year: 2006
Journal: Nat Immunol
Title: Regulation of T cell development by the deubiquitinating enzyme CYLD.
Volume: 7
Issue: 4
Pages: 411-7
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Publication
33309741 | J:312527
First Author: Lee JH
Year: 2021
Journal: J Allergy Clin Immunol
Title: The deubiquitinase CYLD controls protective immunity against helminth infection by regulation of Treg cell plasticity.
Volume: 148
Issue: 1
Pages: 209-224.e9
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Publication
27545878 | J:238931
First Author: Kupka S
Year: 2016
Journal: Cell Rep
Title: SPATA2-Mediated Binding of CYLD to HOIP Enables CYLD Recruitment to Signaling Complexes.
Volume: 16
Issue: 9
Pages: 2271-80
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Publication
22698400 | J:189286
First Author: Nikolaou K
Year: 2012
Journal: Cancer Cell
Title: Inactivation of the deubiquitinase CYLD in hepatocytes causes apoptosis, inflammation, fibrosis, and cancer.
Volume: 21
Issue: 6
Pages: 738-50
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Publication
27681433 | J:240569
First Author: Klei LR
Year: 2016
Journal: Cell Rep
Title: MALT1 Protease Activation Triggers Acute Disruption of Endothelial Barrier Integrity via CYLD Cleavage.
Volume: 17
Issue: 1
Pages: 221-232
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Publication
23575688 | J:293687
 
First Author: Komatsu K
Year: 2013
Journal: Nat Commun
Title: Inhibition of PDE4B suppresses inflammation by increasing expression of the deubiquitinase CYLD.
Volume: 4
Pages: 1684
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Publication
21946435 | J:335028
First Author: Zhang M
Year: 2011
Journal: Cell Mol Immunol
Title: Regulation of antiviral innate immunity by deubiquitinase CYLD.
Volume: 8
Issue: 6
Pages: 502-4
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Publication
27342122 | J:335029
First Author: Zhang J
Year: 2016
Journal: Neuropharmacology
Title: Altered striatal rhythmic activity in cylindromatosis knock-out mice due to enhanced GABAergic inhibition.
Volume: 110
Issue: Pt A
Pages: 260-267
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Publication
20644164 | J:162622
First Author: Tsagaratou A
Year: 2010
Journal: J Immunol
Title: Thymocyte-specific truncation of the deubiquitinating domain of CYLD impairs positive selection in a NF-kappaB essential modulator-dependent manner.
Volume: 185
Issue: 4
Pages: 2032-43
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Publication
20836156 | J:165809
First Author: Bros M
Year: 2010
Journal: Eur J Immunol
Title: Mutated cylindromatosis gene affects the functional state of dendritic cells.
Volume: 40
Issue: 10
Pages: 2848-57
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Publication
31715338 | J:285648
 
First Author: Nguyen J
Year: 2020
Journal: Bone
Title: CYLD, a mechanosensitive deubiquitinase, regulates TGFβ signaling in load-induced bone formation.
Volume: 131
Pages: 115148
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Publication
31900337 | J:284039
First Author: Komatsu K
Year: 2020
Journal: J Immunol
Title: Vinpocetine Suppresses Streptococcus pneumoniae-Induced Inflammation via Inhibition of ERK1 by CYLD.
Volume: 204
Issue: 4
Pages: 933-942
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Publication
17925880 | J:293883
First Author: Lim JH
Year: 2007
Journal: PLoS One
Title: Tumor suppressor CYLD acts as a negative regulator for non-typeable Haemophilus influenza-induced inflammation in the middle ear and lung of mice.
Volume: 2
Issue: 10
Pages: e1032
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Publication
20224552 | J:160381
First Author: Lee AJ
Year: 2010
Journal: EMBO J
Title: Regulation of natural killer T-cell development by deubiquitinase CYLD.
Volume: 29
Issue: 9
Pages: 1600-12
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Publication
21478324 | J:244683
First Author: Miliani de Marval P
Year: 2011
Journal: Cancer Prev Res (Phila)
Title: CYLD inhibits tumorigenesis and metastasis by blocking JNK/AP1 signaling at multiple levels.
Volume: 4
Issue: 6
Pages: 851-9
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Publication
23335970 | J:195859
First Author: Thuille N
Year: 2013
Journal: PLoS One
Title: PKCθ/β and CYLD are antagonistic partners in the NFκB and NFAT transactivation pathways in primary mouse CD3+ T lymphocytes.
Volume: 8
Issue: 1
Pages: e53709
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Publication
27372382 | J:335031
 
First Author: Reuter S
Year: 2016
Journal: Cell Immunol
Title: Cylindromatosis (Cyld) gene mutation in T cells promotes the development of an IL-9-dependent allergic phenotype in experimental asthma.
Volume: 308
Pages: 27-34
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Publication
23300340 | J:260205
First Author: Yang WL
Year: 2013
Journal: Sci Signal
Title: Cycles of ubiquitination and deubiquitination critically regulate growth factor-mediated activation of Akt signaling.
Volume: 6
Issue: 257
Pages: ra3
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Publication
24461064 | J:215707
First Author: Takiuchi T
Year: 2014
Journal: Genes Cells
Title: Suppression of LUBAC-mediated linear ubiquitination by a specific interaction between LUBAC and the deubiquitinases CYLD and OTULIN.
Volume: 19
Issue: 3
Pages: 254-72
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Publication
27028867 | J:311973
First Author: Ran J
Year: 2016
Journal: Oncotarget
Title: Functional interplay between cylindromatosis and histone deacetylase 6 in ciliary homeostasis revealed by phenotypic analysis of double knockout mice.
Volume: 7
Issue: 19
Pages: 27527-37
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Publication
17053834 | J:114972
First Author: Zhang J
Year: 2006
Journal: J Clin Invest
Title: Impaired regulation of NF-kappaB and increased susceptibility to colitis-associated tumorigenesis in CYLD-deficient mice.
Volume: 116
Issue: 11
Pages: 3042-9
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Publication
18467330 | J:138116
First Author: Zhang M
Year: 2008
Journal: J Biol Chem
Title: Regulation of IkappaB kinase-related kinases and antiviral responses by tumor suppressor CYLD.
Volume: 283
Issue: 27
Pages: 18621-6
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Publication
29352268 | J:268196
First Author: Ganjam GK
Year: 2018
Journal: Cell Death Differ
Title: Cylindromatosis mediates neuronal cell death in vitro and in vivo.
Volume: 25
Issue: 8
Pages: 1394-1407
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Publication
21728169 | J:177289
First Author: Tsagaratou A
Year: 2011
Journal: Eur J Immunol
Title: Differential requirement of IKK2 for CYLD-dependent representation of thymic and peripheral T-cell populations.
Volume: 41
Issue: 10
Pages: 3054-62
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Publication
20233721 | J:163899
First Author: Lee AJ
Year: 2010
Journal: J Biol Chem
Title: CARMA1 regulation of regulatory T cell development involves modulation of interleukin-2 receptor signaling.
Volume: 285
Issue: 21
Pages: 15696-703
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Publication
17981138 | J:127468
First Author: Wright A
Year: 2007
Journal: Dev Cell
Title: Regulation of early wave of germ cell apoptosis and spermatogenesis by deubiquitinating enzyme CYLD.
Volume: 13
Issue: 5
Pages: 705-16
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Publication
17923499 | J:126113
First Author: Hövelmeyer N
Year: 2007
Journal: J Exp Med
Title: Regulation of B cell homeostasis and activation by the tumor suppressor gene CYLD.
Volume: 204
Issue: 11
Pages: 2615-27
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Publication
28701375 | J:244164
First Author: Wei R
Year: 2017
Journal: Genes Dev
Title: SPATA2 regulates the activation of RIPK1 by modulating linear ubiquitination.
Volume: 31
Issue: 11
Pages: 1162-1176
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Protein Coding Gene
MGP_CAROLIEiJ_G0031361 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0033923 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0033906 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0033832 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0033899 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0033609 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1921506 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0034419 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0032940 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0033585 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0033738 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0033685 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0033830 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0033728 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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