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Search results 1 to 100 out of 348 for Cyld

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Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Drosophila melanogaster
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Reiley WW
Year: 2007
Journal: J Exp Med
Title: Deubiquitinating enzyme CYLD negatively regulates the ubiquitin-dependent kinase Tak1 and prevents abnormal T cell responses.
Volume: 204
Issue: 6
Pages: 1475-85
Publication  
First Author: Eguether T
Year: 2014
Journal: Nat Commun
Title: The deubiquitinating enzyme CYLD controls apical docking of basal bodies in ciliated epithelial cells.
Volume: 5
Pages: 4585
Publication
First Author: Massoumi R
Year: 2006
Journal: Cell
Title: Cyld inhibits tumor cell proliferation by blocking Bcl-3-dependent NF-kappaB signaling.
Volume: 125
Issue: 4
Pages: 665-77
Publication
First Author: Pannem RR
Year: 2014
Journal: Carcinogenesis
Title: CYLD controls c-MYC expression through the JNK-dependent signaling pathway in hepatocellular carcinoma.
Volume: 35
Issue: 2
Pages: 461-8
Publication
First Author: Reissig S
Year: 2012
Journal: J Immunol
Title: The tumor suppressor CYLD controls the function of murine regulatory T cells.
Volume: 189
Issue: 10
Pages: 4770-6
Publication
First Author: Yang Y
Year: 2014
Journal: Cell Res
Title: CYLD mediates ciliogenesis in multiple organs by deubiquitinating Cep70 and inactivating HDAC6.
Volume: 24
Issue: 11
Pages: 1342-53
Publication
First Author: Yang Y
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: CYLD regulates spindle orientation by stabilizing astral microtubules and promoting dishevelled-NuMA-dynein/dynactin complex formation.
Volume: 111
Issue: 6
Pages: 2158-63
Publication
First Author: Jin W
Year: 2007
Journal: J Biol Chem
Title: Deubiquitinating enzyme CYLD regulates the peripheral development and naive phenotype maintenance of B cells.
Volume: 282
Issue: 21
Pages: 15884-93
Publication
First Author: Chu Y
Year: 2012
Journal: J Immunol
Title: A20 and CYLD do not share significant overlapping functions during B cell development and activation.
Volume: 189
Issue: 9
Pages: 4437-43
Publication
First Author: Karatzas DN
Year: 2016
Journal: Cell Oncol (Dordr)
Title: Inactivation of CYLD in intestinal epithelial cells exacerbates colitis-associated colorectal carcinogenesis - a short report.
Volume: 39
Issue: 3
Pages: 287-93
Publication
First Author: Liang G
Year: 2011
Journal: PLoS One
Title: Serum response factor controls CYLD expression via MAPK signaling pathway.
Volume: 6
Issue: 5
Pages: e19613
Publication
First Author: Mukherjee S
Year: 2020
Journal: Nat Immunol
Title: Deubiquitination of NLRP6 inflammasome by Cyld critically regulates intestinal inflammation.
Volume: 21
Issue: 6
Pages: 626-635
Publication
First Author: Xie W
Year: 2017
Journal: J Genet Genomics
Title: The tumor suppressor CYLD controls epithelial morphogenesis and homeostasis by regulating mitotic spindle behavior and adherens junction assembly.
Volume: 44
Issue: 7
Pages: 343-353
Publication  
First Author: Li HD
Year: 2021
Journal: Front Cell Neurosci
Title: Deficiency of the CYLD Impairs Fear Memory of Mice and Disrupts Neuronal Activity and Synaptic Transmission in the Basolateral Amygdala.
Volume: 15
Pages: 740165
Publication  
First Author: Lim JH
Year: 2012
Journal: Nat Commun
Title: CYLD negatively regulates transforming growth factor-β-signalling via deubiquitinating Akt.
Volume: 3
Pages: 771
Publication
First Author: Srokowski CC
Year: 2009
Journal: Blood
Title: Naturally occurring short splice variant of CYLD positively regulates dendritic cell function.
Volume: 113
Issue: 23
Pages: 5891-5
Publication  
First Author: Pseftogas A
Year: 2020
Journal: Cancers (Basel)
Title: The Tumor Suppressor CYLD Inhibits Mammary Epithelial to Mesenchymal Transition by the Coordinated Inhibition of YAP/TAZ and TGF Signaling.
Volume: 12
Issue: 8
Publication
First Author: Jin W
Year: 2008
Journal: J Clin Invest
Title: Deubiquitinating enzyme CYLD negatively regulates RANK signaling and osteoclastogenesis in mice.
Volume: 118
Issue: 5
Pages: 1858-66
Publication
First Author: Yu B
Year: 2017
Journal: Arterioscler Thromb Vasc Biol
Title: CYLD Deubiquitinates Nicotinamide Adenine Dinucleotide Phosphate Oxidase 4 Contributing to Adventitial Remodeling.
Volume: 37
Issue: 9
Pages: 1698-1709
Publication
First Author: Nishanth G
Year: 2013
Journal: PLoS Pathog
Title: CYLD enhances severe listeriosis by impairing IL-6/STAT3-dependent fibrin production.
Volume: 9
Issue: 6
Pages: e1003455
Publication
First Author: Tsagaratou A
Year: 2011
Journal: PLoS One
Title: Truncation of the deubiquitinating domain of CYLD in myelomonocytic cells attenuates inflammatory responses.
Volume: 6
Issue: 1
Pages: e16397
Gene
Type: gene
Organism: Homo sapiens
Publication
First Author: Legarda D
Year: 2016
Journal: Cell Rep
Title: CYLD Proteolysis Protects Macrophages from TNF-Mediated Auto-necroptosis Induced by LPS and Licensed by Type I IFN.
Volume: 15
Issue: 11
Pages: 2449-61
Publication
First Author: Wurm R
Year: 2015
Journal: Eur J Immunol
Title: Protective dendritic cell responses against listeriosis induced by the short form of the deubiquitinating enzyme CYLD are inhibited by full-length CYLD.
Volume: 45
Issue: 5
Pages: 1366-76
Publication  
First Author: Wang H
Year: 2015
Journal: J Mol Cell Cardiol
Title: Deubiquitinating enzyme CYLD mediates pressure overload-induced cardiac maladaptive remodeling and dysfunction via downregulating Nrf2.
Volume: 84
Pages: 143-53
Publication
First Author: Wang WY
Year: 2014
Journal: PLoS One
Title: CYLD negatively regulates nontypeable Haemophilus influenzae-induced IL-8 expression via phosphatase MKP-1-dependent inhibition of ERK.
Volume: 9
Issue: 11
Pages: e112516
Publication
First Author: Espinosa L
Year: 2010
Journal: Cancer Cell
Title: The Notch/Hes1 pathway sustains NF-κB activation through CYLD repression in T cell leukemia.
Volume: 18
Issue: 3
Pages: 268-81
Publication
First Author: Zhao Y
Year: 2011
Journal: J Biol Chem
Title: The deubiquitinase CYLD targets Smad7 protein to regulate transforming growth factor β (TGF-β) signaling and the development of regulatory T cells.
Volume: 286
Issue: 47
Pages: 40520-30
Publication
First Author: Tang Y
Year: 2019
Journal: Gastroenterology
Title: Alternative Splice Forms of CYLD Mediate Ubiquitination of SMAD7 to Prevent TGFB Signaling and Promote Colitis.
Volume: 156
Issue: 3
Pages: 692-707.e7
Publication
First Author: Wickström SA
Year: 2010
Journal: EMBO J
Title: CYLD negatively regulates cell-cycle progression by inactivating HDAC6 and increasing the levels of acetylated tubulin.
Volume: 29
Issue: 1
Pages: 131-44
Publication
First Author: Xie W
Year: 2022
Journal: Cell Rep
Title: CYLD deubiquitinates plakoglobin to promote Cx43 membrane targeting and gap junction assembly in the heart.
Volume: 41
Issue: 13
Pages: 111864
Publication
First Author: Yu Q
Year: 2020
Journal: Artif Cells Nanomed Biotechnol
Title: CYLD expression in dendritic cells involved in the immunoregulation of pulmonary adenocarcinoma via NF-κB pathway.
Volume: 48
Issue: 1
Pages: 137-142
Publication
First Author: Li L
Year: 2019
Journal: Biochem Biophys Res Commun
Title: CYLD deficiency exacerbates lipopolysaccharide (LPS)-induced pyroptosis in astrocytes of mice with sepsis.
Volume: 514
Issue: 4
Pages: 1066-1073
Publication  
First Author: Alameda JP
Year: 2021
Journal: Int J Mol Sci
Title: CYLD Inhibits the Development of Skin Squamous Cell Tumors in Immunocompetent Mice.
Volume: 22
Issue: 13
Publication  
First Author: Qi L
Year: 2020
Journal: J Mol Cell Cardiol
Title: CYLD exaggerates pressure overload-induced cardiomyopathy via suppressing autolysosome efflux in cardiomyocytes.
Volume: 145
Pages: 59-73
Publication
First Author: Zhao Y
Year: 2015
Journal: J Biol Chem
Title: CYLD and the NEMO Zinc Finger Regulate Tumor Necrosis Factor Signaling and Early Embryogenesis.
Volume: 290
Issue: 36
Pages: 22076-84
Publication
First Author: Lee BC
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Deubiquitinase CYLD acts as a negative regulator for bacterium NTHi-induced inflammation by suppressing K63-linked ubiquitination of MyD88.
Volume: 113
Issue: 2
Pages: E165-71
Publication  
First Author: Fernández-Majada V
Year: 2016
Journal: Nat Commun
Title: The tumour suppressor CYLD regulates the p53 DNA damage response.
Volume: 7
Pages: 12508
Publication
First Author: Ahmed N
Year: 2011
Journal: Nat Immunol
Title: The E3 ligase Itch and deubiquitinase Cyld act together to regulate Tak1 and inflammation.
Volume: 12
Issue: 12
Pages: 1176-83
Publication
First Author: Lim JH
Year: 2007
Journal: Immunity
Title: Tumor suppressor CYLD regulates acute lung injury in lethal Streptococcus pneumoniae infections.
Volume: 27
Issue: 2
Pages: 349-60
Publication
First Author: Lee JH
Year: 2021
Journal: J Allergy Clin Immunol
Title: The deubiquitinase CYLD controls protective immunity against helminth infection by regulation of Treg cell plasticity.
Volume: 148
Issue: 1
Pages: 209-224.e9
Publication
First Author: Reiley WW
Year: 2006
Journal: Nat Immunol
Title: Regulation of T cell development by the deubiquitinating enzyme CYLD.
Volume: 7
Issue: 4
Pages: 411-7
Publication
First Author: Kupka S
Year: 2016
Journal: Cell Rep
Title: SPATA2-Mediated Binding of CYLD to HOIP Enables CYLD Recruitment to Signaling Complexes.
Volume: 16
Issue: 9
Pages: 2271-80
Publication
First Author: Nikolaou K
Year: 2012
Journal: Cancer Cell
Title: Inactivation of the deubiquitinase CYLD in hepatocytes causes apoptosis, inflammation, fibrosis, and cancer.
Volume: 21
Issue: 6
Pages: 738-50
Publication
First Author: Klei LR
Year: 2016
Journal: Cell Rep
Title: MALT1 Protease Activation Triggers Acute Disruption of Endothelial Barrier Integrity via CYLD Cleavage.
Volume: 17
Issue: 1
Pages: 221-232
Publication
First Author: Tsagaratou A
Year: 2010
Journal: J Immunol
Title: Thymocyte-specific truncation of the deubiquitinating domain of CYLD impairs positive selection in a NF-kappaB essential modulator-dependent manner.
Volume: 185
Issue: 4
Pages: 2032-43
Publication  
First Author: Komatsu K
Year: 2013
Journal: Nat Commun
Title: Inhibition of PDE4B suppresses inflammation by increasing expression of the deubiquitinase CYLD.
Volume: 4
Pages: 1684
Publication
First Author: Bros M
Year: 2010
Journal: Eur J Immunol
Title: Mutated cylindromatosis gene affects the functional state of dendritic cells.
Volume: 40
Issue: 10
Pages: 2848-57
Publication
First Author: Komatsu K
Year: 2020
Journal: J Immunol
Title: Vinpocetine Suppresses Streptococcus pneumoniae-Induced Inflammation via Inhibition of ERK1 by CYLD.
Volume: 204
Issue: 4
Pages: 933-942
Publication  
First Author: Nguyen J
Year: 2020
Journal: Bone
Title: CYLD, a mechanosensitive deubiquitinase, regulates TGFβ signaling in load-induced bone formation.
Volume: 131
Pages: 115148
MGI Directed Relationship Property
Name: Non-mouse_Gene_Symbol
Value: CYLD
Publication
First Author: Lim JH
Year: 2007
Journal: PLoS One
Title: Tumor suppressor CYLD acts as a negative regulator for non-typeable Haemophilus influenza-induced inflammation in the middle ear and lung of mice.
Volume: 2
Issue: 10
Pages: e1032
Publication
First Author: Lee AJ
Year: 2010
Journal: EMBO J
Title: Regulation of natural killer T-cell development by deubiquitinase CYLD.
Volume: 29
Issue: 9
Pages: 1600-12
Publication
First Author: Miliani de Marval P
Year: 2011
Journal: Cancer Prev Res (Phila)
Title: CYLD inhibits tumorigenesis and metastasis by blocking JNK/AP1 signaling at multiple levels.
Volume: 4
Issue: 6
Pages: 851-9
Publication
First Author: Thuille N
Year: 2013
Journal: PLoS One
Title: PKCθ/β and CYLD are antagonistic partners in the NFκB and NFAT transactivation pathways in primary mouse CD3+ T lymphocytes.
Volume: 8
Issue: 1
Pages: e53709
Publication
First Author: Yang WL
Year: 2013
Journal: Sci Signal
Title: Cycles of ubiquitination and deubiquitination critically regulate growth factor-mediated activation of Akt signaling.
Volume: 6
Issue: 257
Pages: ra3
Publication
First Author: Takiuchi T
Year: 2014
Journal: Genes Cells
Title: Suppression of LUBAC-mediated linear ubiquitination by a specific interaction between LUBAC and the deubiquitinases CYLD and OTULIN.
Volume: 19
Issue: 3
Pages: 254-72
Publication
First Author: Ran J
Year: 2016
Journal: Oncotarget
Title: Functional interplay between cylindromatosis and histone deacetylase 6 in ciliary homeostasis revealed by phenotypic analysis of double knockout mice.
Volume: 7
Issue: 19
Pages: 27527-37
Publication
First Author: Zhang M
Year: 2008
Journal: J Biol Chem
Title: Regulation of IkappaB kinase-related kinases and antiviral responses by tumor suppressor CYLD.
Volume: 283
Issue: 27
Pages: 18621-6
Publication
First Author: Zhang J
Year: 2006
Journal: J Clin Invest
Title: Impaired regulation of NF-kappaB and increased susceptibility to colitis-associated tumorigenesis in CYLD-deficient mice.
Volume: 116
Issue: 11
Pages: 3042-9
Publication
First Author: Ganjam GK
Year: 2018
Journal: Cell Death Differ
Title: Cylindromatosis mediates neuronal cell death in vitro and in vivo.
Volume: 25
Issue: 8
Pages: 1394-1407
Publication
First Author: Tsagaratou A
Year: 2011
Journal: Eur J Immunol
Title: Differential requirement of IKK2 for CYLD-dependent representation of thymic and peripheral T-cell populations.
Volume: 41
Issue: 10
Pages: 3054-62
Publication
First Author: Wright A
Year: 2007
Journal: Dev Cell
Title: Regulation of early wave of germ cell apoptosis and spermatogenesis by deubiquitinating enzyme CYLD.
Volume: 13
Issue: 5
Pages: 705-16
Publication
First Author: Lee AJ
Year: 2010
Journal: J Biol Chem
Title: CARMA1 regulation of regulatory T cell development involves modulation of interleukin-2 receptor signaling.
Volume: 285
Issue: 21
Pages: 15696-703
Publication
First Author: Hövelmeyer N
Year: 2007
Journal: J Exp Med
Title: Regulation of B cell homeostasis and activation by the tumor suppressor gene CYLD.
Volume: 204
Issue: 11
Pages: 2615-27
Publication
First Author: Wei R
Year: 2017
Journal: Genes Dev
Title: SPATA2 regulates the activation of RIPK1 by modulating linear ubiquitination.
Volume: 31
Issue: 11
Pages: 1162-1176
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression  
Probe: MGI:952015
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824156
Age: embryonic day 14.5
Image: euxassay_001691_06
Specimen Label: euxassay_001691_06
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:952015
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824156
Age: embryonic day 14.5
Image: euxassay_001691_07
Specimen Label: euxassay_001691_07
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:952015
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824156
Age: embryonic day 14.5
Image: euxassay_001691_08
Specimen Label: euxassay_001691_08
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:952015
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824156
Age: embryonic day 14.5
Image: euxassay_001691_09
Specimen Label: euxassay_001691_09
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:952015
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824156
Age: embryonic day 14.5
Image: euxassay_001691_12
Specimen Label: euxassay_001691_12
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:952015
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824156
Age: embryonic day 14.5
Image: euxassay_001691_13
Specimen Label: euxassay_001691_13
Detected: true
Specimen Num: 13
GXD Expression  
Probe: MGI:952015
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824156
Age: embryonic day 14.5
Image: euxassay_001691_14
Specimen Label: euxassay_001691_14
Detected: true
Specimen Num: 14
GXD Expression  
Probe: MGI:952015
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824156
Age: embryonic day 14.5
Image: euxassay_001691_15
Specimen Label: euxassay_001691_15
Detected: true
Specimen Num: 15
GXD Expression  
Probe: MGI:952015
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824156
Age: embryonic day 14.5
Image: euxassay_001691_16
Specimen Label: euxassay_001691_16
Detected: true
Specimen Num: 16
GXD Expression  
Probe: MGI:952015
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1636323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824156
Age: embryonic day 14.5
Image: euxassay_001691_09
Specimen Label: euxassay_001691_09
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:952015
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1636323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824156
Age: embryonic day 14.5
Image: euxassay_001691_10
Specimen Label: euxassay_001691_10
Detected: true
Specimen Num: 10