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Search results 1 to 100 out of 1132 for Dct

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0.044s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
GXD Expression
Probe: MGI:6467316
Assay Type: Immunohistochemistry
Annotation Date: 2020-10-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3727823
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:6467320
Age: embryonic day 15.5
Image: 3K DCT
Note: Correlation between Dct and Col4a1 expression was similar compared with wild-type controls.
Specimen Label: 3K DCT
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:6467316
Assay Type: Immunohistochemistry
Annotation Date: 2020-10-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3727823
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:6467320
Age: embryonic day 15.5
Image: 3J DCT
Specimen Label: 3J DCT
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:3207553
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824254
Age: embryonic day 14.5
Image: S6 C/D - Dct
Note: Expression is present in the lateral and dorsal pallium.
Specimen Label: S6 C/D - Dct
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3207553
Assay Type: RNA in situ
Annotation Date: 2009-01-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3564922
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3826012
Age: embryonic day 14.5
Image: Additional file 4 Dct
Specimen Label: Additional file 4 Dct
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:3207553
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824254
Age: embryonic day 14.5
Image: S6 E/F - Dct
Note: Expression is present in the lateral pallium.
Specimen Label: S6 E/F - Dct
Detected: true
Specimen Num: 2
Publication
First Author: Guyonneau L
Year: 2004
Journal: Mol Cell Biol
Title: Melanocytes and pigmentation are affected in dopachrome tautomerase knockout mice.
Volume: 24
Issue: 8
Pages: 3396-403
Publication
First Author: Levin MD
Year: 2009
Journal: J Clin Invest
Title: Melanocyte-like cells in the heart and pulmonary veins contribute to atrial arrhythmia triggers.
Volume: 119
Issue: 11
Pages: 3420-36
Publication
First Author: Jiang S
Year: 2010
Journal: Free Radic Biol Med
Title: Regulation of DHICA-mediated antioxidation by dopachrome tautomerase: implication for skin photoprotection against UVA radiation.
Volume: 48
Issue: 9
Pages: 1144-51
Publication
First Author: Nishimura EK
Year: 2010
Journal: Cell Stem Cell
Title: Key roles for transforming growth factor beta in melanocyte stem cell maintenance.
Volume: 6
Issue: 2
Pages: 130-40
Publication
First Author: Tanimura S
Year: 2011
Journal: Cell Stem Cell
Title: Hair follicle stem cells provide a functional niche for melanocyte stem cells.
Volume: 8
Issue: 2
Pages: 177-87
Publication
First Author: Eshiba S
Year: 2021
Journal: Cell Rep
Title: Stem cell spreading dynamics intrinsically differentiate acral melanomas from nevi.
Volume: 36
Issue: 5
Pages: 109492
Publication
First Author: Aoki H
Year: 2015
Journal: Genes Cells
Title: White spotting phenotype induced by targeted REST disruption during neural crest specification to a melanocyte cell lineage.
Volume: 20
Issue: 5
Pages: 439-49
Publication
First Author: Guyonneau L
Year: 2002
Journal: Pigment Cell Res
Title: Expression of Cre recombinase in pigment cells.
Volume: 15
Issue: 4
Pages: 305-9
Publication
First Author: Nishikawa-Torikai S
Year: 2011
Journal: J Invest Dermatol
Title: Functional characterization of melanocyte stem cells in hair follicles.
Volume: 131
Issue: 12
Pages: 2358-67
Publication
First Author: Choi YS
Year: 2022
Journal: Cell
Title: Topical therapy for regression and melanoma prevention of congenital giant nevi.
Volume: 185
Issue: 12
Pages: 2071-2085.e12
Publication  
First Author: Dörner J
Year: 2017
Journal: Mol Cell Endocrinol
Title: GLI1+ progenitor cells in the adrenal capsule of the adult mouse give rise to heterotopic gonadal-like tissue.
Volume: 441
Pages: 164-175
Publication
First Author: Aoki H
Year: 2009
Journal: Development
Title: Two distinct types of mouse melanocyte: differential signaling requirement for the maintenance of non-cutaneous and dermal versus epidermal melanocytes.
Volume: 136
Issue: 15
Pages: 2511-21
Publication
First Author: Inoue-Narita T
Year: 2008
Journal: Cancer Res
Title: Pten deficiency in melanocytes results in resistance to hair graying and susceptibility to carcinogen-induced melanomagenesis.
Volume: 68
Issue: 14
Pages: 5760-8
Publication
First Author: Dankort D
Year: 2009
Journal: Nat Genet
Title: Braf(V600E) cooperates with Pten loss to induce metastatic melanoma.
Volume: 41
Issue: 5
Pages: 544-52
Publication
First Author: Raviv S
Year: 2014
Journal: PLoS Genet
Title: PAX6 regulates melanogenesis in the retinal pigmented epithelium through feed-forward regulatory interactions with MITF.
Volume: 10
Issue: 5
Pages: e1004360
Allele
Name: dopachrome tautomerase; targeted mutation 1, Friedrich Beermann
Allele Type: Targeted
Attribute String: Recombinase
GXD Expression  
Probe: MGI:7334914
Assay Type: RNA in situ
Annotation Date: 2022-09-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1654015
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:7335019
Age: embryonic day 9.5
Note: Expression is seen in the dorsal optic vesicle.
Specimen Label: 4 Dct
Detected: true
Specimen Num: 1
Allele
Name: dopachrome tautomerase; endonuclease-mediated mutation 1, Emi K Nishimura
Allele Type: Endonuclease-mediated
Attribute String: Inducible, Null/knockout, Recombinase
Genotype
Symbol: Dct/Dct<+> Gt(ROSA)26Sor/Gt(ROSA)26Sor<+>
Background: involves: C57BL/6NCrlj * CBA/JNCrlj
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Dct/Dct Tgfbr2/Tgfbr2 Tg(Dct-lacZ)A12Jkn/?
Background: involves: 129/Sv * C57BL/6 * C57BL/6J * CBA
Zygosity: cn
Has Mutant Allele: true
GXD Expression
Probe: MGI:2385688
Assay Type: RNA in situ
Annotation Date: 2017-06-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1675019
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:5898553
Age: embryonic day 11.5
Image: 3C
Note: Overlap of Mitf and Dct expression away from midline.
Specimen Label: 3C
Detected: true
Specimen Num: 3
Strain
Attribute String: targeted mutation, mutant stock
Allele
Name: transgene insertion 3510, Friedrich Beermann
Allele Type: Transgenic
Attribute String: Recombinase
Publication
First Author: Davis N
Year: 2009
Journal: Dev Biol
Title: Pax6 dosage requirements in iris and ciliary body differentiation.
Volume: 333
Issue: 1
Pages: 132-42
Publication
First Author: Davis N
Year: 2011
Journal: Development
Title: Roles for Dicer1 in the patterning and differentiation of the optic cup neuroepithelium.
Volume: 138
Issue: 1
Pages: 127-38
Publication  
First Author: Cohen-Tayar Y
Year: 2018
Journal: Development
Title: Pax6 regulation of Sox9 in the mouse retinal pigmented epithelium controls its timely differentiation and choroid vasculature development.
Volume: 145
Issue: 15
Allele
Name: transgene insertion 1, Ruth Ashery-Padan
Allele Type: Transgenic
Attribute String: Recombinase
Publication
First Author: Naftelberg S
Year: 2016
Journal: PLoS Genet
Title: Phosphatidylserine Ameliorates Neurodegenerative Symptoms and Enhances Axonal Transport in a Mouse Model of Familial Dysautonomia.
Volume: 12
Issue: 12
Pages: e1006486
Genotype
Symbol: Dct/Dct
Background: involves: 129/Sv * C57BL/6
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Pax6/Pax6<+> Tg(Dct-cre)1Apdn/?
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Pax6/Pax6<+> Tg(CAG-EGFP,-Pax6,-lacZ)1Stoy/? Tg(Dct-cre)1Apdn/?
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Pax6/Pax6<+> Tg(CAG-EGFP,-Pax6*5a,-lacZ)1Stoy/? Tg(Dct-cre)1Apdn/?
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Pax6/Pax6 Tg(Dct-cre)1Apdn/?
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(CAG-EGFP,-Pax6*5a,-lacZ)1Stoy/? Tg(Dct-cre)1Apdn/?
Background: Not Specified
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(CAG-EGFP,-Pax6,-lacZ)1Stoy/? Tg(Dct-cre)1Apdn/?
Background: Not Specified
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Dct/Dct<+> Rest/Rest<+>
Background: involves: 129/Sv * 129S4/SvJae * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Dct/Dct<+> Rest/Rest
Background: involves: 129/Sv * 129S4/SvJae * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Elp1/Elp1 Tg(Dct-cre)1Apdn/?
Background: involves: 129S7/SvEvBrd * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Sox9/Sox9 Tg(Dct-cre)1Apdn/?
Background: involves: 129S7/SvEvBrd * ICR
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Dct/Dct<+> Tg(CAG-Bgeo/GFP)21Lbe/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Dct/Dct<+>
Background: involves: 129S4/SvJaeSor * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(CAG-EGFP,-Pax6*5a,-lacZ)1Stoy/? Tg(Dct-cre)1Apdn/?
Background: involves: C57BL/6 * ICR
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(CAG-EGFP,-Pax6,-lacZ)1Stoy/? Tg(Dct-cre)1Apdn/?
Background: involves: C57BL/6 * ICR
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(CAG-Bgeo/ALPP)1Lbe/? Tg(Dct-cre)1Apdn/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * ICR
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Dicer1/Dicer1 Tg(Dct-cre)1Apdn/?
Background: involves: 129
Zygosity: cn
Has Mutant Allele: true
GXD Expression
Probe: MGI:6467316
Assay Type: Immunohistochemistry
Annotation Date: 2020-10-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3727823
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:6467319
Age: embryonic day 15.5
Image: 3B
Note: Authors report similar numbers of Dct and EdU double-labeled cells in mutant and control embryos at both time points.
Specimen Label: 3B
Detected: true
Specimen Num: 8
GXD Expression
Probe: MGI:6467316
Assay Type: Immunohistochemistry
Annotation Date: 2020-10-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3727823
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:6467319
Age: embryonic day 15.5
Image: 3A
Note: Authors report similar numbers of Dct and EdU double-labeled cells in mutant and control embryos at both time points.
Specimen Label: 3A
Detected: true
Specimen Num: 7
GXD Expression
Probe: MGI:6467316
Assay Type: Immunohistochemistry
Annotation Date: 2020-10-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3727823
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:6467319
Age: embryonic day 15.5
Image: 3C
Note: Authors report similar numbers of Dct and EdU double-labeled cells in mutant and control embryos at both time points.
Specimen Label: 3C
Detected: true
Specimen Num: 9
GXD Expression
Probe: MGI:1332524
Assay Type: RNA in situ
Annotation Date: 2006-05-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1677919
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:3622902
Age: embryonic day 11.5
Image: 1.B.inset
Note: Double label in situ hybridization where black represents Mitf expression and red represents Dct expression. Many cells coexpress Mitf and Dct.
Specimen Label: 1.B.inset
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:2385688
Assay Type: RNA in situ
Annotation Date: 2017-06-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1618219
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:5898553
Age: embryonic day 11.5
Image: 3B
Note: In the trunk, authors report overlap of Dct and Mtif expression in majority of more lateral cells, but not in those closer to dorsal midline.
Specimen Label: 3B
Detected: true
Specimen Num: 2
Publication
First Author: Jordan SA
Year: 2000
Journal: Dev Biol
Title: MGF (KIT ligand) is a chemokinetic factor for melanoblast migration into hair follicles.
Volume: 225
Issue: 2
Pages: 424-36
GO Term
GO Term
Publication
First Author: Hozumi H
Year: 2012
Journal: Genes Cells
Title: Impaired development of melanoblasts in the black-eyed white Mitf(mi-bw) mouse, a model for auditory-pigmentary disorders.
Volume: 17
Issue: 6
Pages: 494-508
Publication
First Author: Zhao S
Year: 1999
Journal: Dev Biol
Title: Tyrosinase-related protein 2 promoter targets transgene expression to ocular and neural crest-derived tissues.
Volume: 216
Issue: 1
Pages: 154-63
Publication
First Author: Baxter LL
Year: 2003
Journal: Gene Expr Patterns
Title: Pmel17 expression is Mitf-dependent and reveals cranial melanoblast migration during murine development.
Volume: 3
Issue: 6
Pages: 703-7
GO Term
Publication
First Author: Pennamen P
Year: 2021
Journal: Genet Med
Title: Dopachrome tautomerase variants in patients with oculocutaneous albinism.
Volume: 23
Issue: 3
Pages: 479-487
Publication
First Author: Costin GE
Year: 2005
Journal: Biochem J
Title: Mutations in dopachrome tautomerase (Dct) affect eumelanin/pheomelanin synthesis, but do not affect intracellular trafficking of the mutant protein.
Volume: 391
Issue: Pt 2
Pages: 249-59
Publication
First Author: Denecker G
Year: 2014
Journal: Cell Death Differ
Title: Identification of a ZEB2-MITF-ZEB1 transcriptional network that controls melanogenesis and melanoma progression.
Volume: 21
Issue: 8
Pages: 1250-61
Publication
First Author: Nakayama A
Year: 1998
Journal: Mech Dev
Title: Mutations in microphthalmia, the mouse homolog of the human deafness gene MITF, affect neuroepithelial and neural crest-derived melanocytes differently.
Volume: 70
Issue: 1-2
Pages: 155-66
Publication
First Author: Ma Y
Year: 2013
Journal: Development
Title: Fascin 1 is transiently expressed in mouse melanoblasts during development and promotes migration and proliferation.
Volume: 140
Issue: 10
Pages: 2203-11
Publication
First Author: Opdecamp K
Year: 1997
Journal: Development
Title: Melanocyte development in vivo and in neural crest cell cultures: crucial dependence on the Mitf basic-helix-loop-helix-zipper transcription factor.
Volume: 124
Issue: 12
Pages: 2377-86
Publication
First Author: Potterf SB
Year: 2001
Journal: Dev Biol
Title: Analysis of SOX10 function in neural crest-derived melanocyte development: SOX10-dependent transcriptional control of dopachrome tautomerase.
Volume: 237
Issue: 2
Pages: 245-57
Publication
First Author: Jiao Z
Year: 2006
Journal: Dev Biol
Title: Dopachrome tautomerase (Dct) regulates neural progenitor cell proliferation.
Volume: 296
Issue: 2
Pages: 396-408
Publication
First Author: Anderson MG
Year: 2008
Journal: Pigment Cell Melanoma Res
Title: Iris phenotypes and pigment dispersion caused by genes influencing pigmentation.
Volume: 21
Issue: 5
Pages: 565-78
Publication
First Author: Costin GE
Year: 2003
Journal: J Cell Sci
Title: Tyrosinase processing and intracellular trafficking is disrupted in mouse primary melanocytes carrying the underwhite (uw) mutation. A model for oculocutaneous albinism (OCA) type 4.
Volume: 116
Issue: Pt 15
Pages: 3203-12
Publication
First Author: Hakami RM
Year: 2006
Journal: Mech Dev
Title: Genetic evidence does not support direct regulation of EDNRB by SOX10 in migratory neural crest and the melanocyte lineage.
Volume: 123
Issue: 2
Pages: 124-34
Publication
First Author: Kim H
Year: 2014
Journal: Biochem Biophys Res Commun
Title: Pax3 function is required specifically for inner ear structures with melanogenic fates.
Volume: 445
Issue: 3
Pages: 608-14
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Tsukamoto K
Year: 1992
Journal: EMBO J
Title: A second tyrosinase-related protein, TRP-2, is a melanogenic enzyme termed DOPAchrome tautomerase.
Volume: 11
Issue: 2
Pages: 519-26
Publication
First Author: Budd PS
Year: 1995
Journal: Genomics
Title: Structure of the mouse tyrosinase-related protein-2/dopachrome tautomerase (Tyrp2/Dct) gene and sequence of two novel slaty alleles.
Volume: 29
Issue: 1
Pages: 35-43
Publication  
First Author: Green MC
Year: 1972
Journal: Mouse News Lett
Title: Slaty (slt)
Volume: 47
Pages: 36