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Search results 1 to 100 out of 1032 for Ddx4

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0.043s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Danio rerio
Gene
Type: gene
Organism: Rattus norvegicus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
GXD Expression  
Probe: MGI:5315099
Assay Type: Immunohistochemistry
Annotation Date: 2020-10-23
Strength: Present
Sex: Female
Emaps: EMAPS:3102528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6468576
Age: postnatal week 23
Image: 1H Ddx4 Control
Specimen Label: 1H Ddx4 Control
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:5315099
Assay Type: Immunohistochemistry
Annotation Date: 2020-10-23
Strength: Present
Sex: Female
Emaps: EMAPS:3102528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6468576
Age: postnatal week 23
Image: 1H Ddx4 cKO
Note: Oogenesis in the mutant is comparable to that seen in controls.
Specimen Label: 1H Ddx4 cKO
Detected: true
Specimen Num: 2
Publication
First Author: Le HT
Year: 2020
Journal: Genesis
Title: Generation of B6-Ddx4em1(CreERT2)Utr , a novel CreERT2 knock-in line, for germ cell lineage by CRISPR/Cas9.
Volume: 58
Issue: 7
Pages: e23367
Publication    
First Author: Carmell MA
Year: 2016
Journal: Elife
Title: A widely employed germ cell marker is an ancient disordered protein with reproductive functions in diverse eukaryotes.
Volume: 5
Publication    
First Author: Lesch BJ
Year: 2019
Journal: Elife
Title: Intergenerational epigenetic inheritance of cancer susceptibility in mammals.
Volume: 8
Publication
First Author: Alpatov R
Year: 2014
Journal: Cell
Title: A chromatin-dependent role of the fragile X mental retardation protein FMRP in the DNA damage response.
Volume: 157
Issue: 4
Pages: 869-81
Publication    
First Author: Kojima ML
Year: 2019
Journal: Elife
Title: Amplification of a broad transcriptional program by a common factor triggers the meiotic cell cycle in mice.
Volume: 8
Publication
First Author: Xia Q
Year: 2021
Journal: Cell Prolif
Title: RNA helicase DDX5 acts as a critical regulator for survival of neonatal mouse gonocytes.
Volume: 54
Issue: 5
Pages: e13000
Publication
First Author: Baker MD
Year: 2014
Journal: Reproduction
Title: The small GTPase Rheb is required for spermatogenesis but not oogenesis.
Volume: 147
Issue: 5
Pages: 615-25
Publication
First Author: Hu YC
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Tumor suppressor gene Rb is required for self-renewal of spermatogonial stem cells in mice.
Volume: 110
Issue: 31
Pages: 12685-90
Publication
First Author: Holt JE
Year: 2014
Journal: Development
Title: The APC/C activator FZR1 is essential for meiotic prophase I in mice.
Volume: 141
Issue: 6
Pages: 1354-65
Publication
First Author: Deguchi K
Year: 2013
Journal: Biol Reprod
Title: Posttranscriptional regulation of histone lysine methyltransferase GLP in embryonic male mouse germ cells.
Volume: 88
Issue: 2
Pages: 36
Publication
First Author: Mak W
Year: 2016
Journal: Biol Reprod
Title: An Important Role of Pumilio 1 in Regulating the Development of the Mammalian Female Germline.
Volume: 94
Issue: 6
Pages: 134
Publication
First Author: Mu W
Year: 2017
Journal: Dev Biol
Title: EZH1 in germ cells safeguards the function of PRC2 during spermatogenesis.
Volume: 424
Issue: 2
Pages: 198-207
Publication  
First Author: Yin Y
Year: 2021
Journal: Cells
Title: Cullin4 E3 Ubiquitin Ligases Regulate Male Gonocyte Migration, Proliferation and Blood-Testis Barrier Homeostasis.
Volume: 10
Issue: 10
Publication
First Author: Shin YH
Year: 2017
Journal: J Clin Invest
Title: Transcription factors SOHLH1 and SOHLH2 coordinate oocyte differentiation without affecting meiosis I.
Volume: 127
Issue: 6
Pages: 2106-2117
Publication
First Author: Shinoda G
Year: 2013
Journal: Stem Cells
Title: Lin28a regulates germ cell pool size and fertility.
Volume: 31
Issue: 5
Pages: 1001-9
Publication  
First Author: Liu W
Year: 2017
Journal: Nat Commun
Title: BCAS2 is involved in alternative mRNA splicing in spermatogonia and the transition to meiosis.
Volume: 8
Pages: 14182
Publication
First Author: Yu C
Year: 2016
Journal: Cell Res
Title: Oocyte-expressed yes-associated protein is a key activator of the early zygotic genome in mouse.
Volume: 26
Issue: 3
Pages: 275-87
Publication
First Author: Soh YQS
Year: 2017
Journal: PLoS Genet
Title: Meioc maintains an extended meiotic prophase I in mice.
Volume: 13
Issue: 4
Pages: e1006704
Publication
First Author: Yu C
Year: 2013
Journal: Science
Title: CRL4 complex regulates mammalian oocyte survival and reprogramming by activation of TET proteins.
Volume: 342
Issue: 6165
Pages: 1518-21
Publication
First Author: Chen SR
Year: 2016
Journal: Cell Death Dis
Title: Does murine spermatogenesis require WNT signalling? A lesson from Gpr177 conditional knockout mouse models.
Volume: 7
Issue: 6
Pages: e2281
Publication
First Author: Nicholls PK
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Mammalian germ cells are determined after PGC colonization of the nascent gonad.
Volume: 116
Issue: 51
Pages: 25677-25687
Publication
First Author: Kato Y
Year: 2019
Journal: EMBO Rep
Title: ELAVL2-directed RNA regulatory network drives the formation of quiescent primordial follicles.
Volume: 20
Issue: 12
Pages: e48251
Publication  
First Author: Abby E
Year: 2016
Journal: Nat Commun
Title: Implementation of meiosis prophase I programme requires a conserved retinoid-independent stabilizer of meiotic transcripts.
Volume: 7
Pages: 10324
Publication
First Author: Yu DCW
Year: 2021
Journal: iScience
Title: Human pluripotent stem cell-derived DDX4 and KRT-8 positive cells participate in ovarian follicle-like structure formation.
Volume: 24
Issue: 1
Pages: 102003
Publication
First Author: Fujiwara Y
Year: 1994
Journal: Proc Natl Acad Sci U S A
Title: Isolation of a DEAD-family protein gene that encodes a murine homolog of Drosophila vasa and its specific expression in germ cell lineage.
Volume: 91
Issue: 25
Pages: 12258-62
Publication
First Author: Kuramochi-Miyagawa S
Year: 2004
Journal: Development
Title: Mili, a mammalian member of piwi family gene, is essential for spermatogenesis.
Volume: 131
Issue: 4
Pages: 839-49
Publication
First Author: Shibata N
Year: 2004
Journal: Mol Reprod Dev
Title: Mouse RanBPM is a partner gene to a germline specific RNA helicase, mouse vasa homolog protein.
Volume: 67
Issue: 1
Pages: 1-7
Publication
First Author: Kuramochi-Miyagawa S
Year: 2010
Journal: Genes Dev
Title: MVH in piRNA processing and gene silencing of retrotransposons.
Volume: 24
Issue: 9
Pages: 887-92
Publication
First Author: Hosokawa M
Year: 2007
Journal: Dev Biol
Title: Tudor-related proteins TDRD1/MTR-1, TDRD6 and TDRD7/TRAP: domain composition, intracellular localization, and function in male germ cells in mice.
Volume: 301
Issue: 1
Pages: 38-52
Allele
Name: transgene insertion 1, Pao-Tien Chuang
Allele Type: Transgenic
Attribute String: Recombinase
Allele
Name: transgene insertion 1, Diego H Castrillon
Allele Type: Transgenic
Attribute String: Inducible, Recombinase
Allele
Name: DEAD box helicase 4; targeted mutation 1, David C Page
Allele Type: Targeted
Attribute String: Recombinase
Publication
First Author: Wenda JM
Year: 2017
Journal: Dev Cell
Title: Distinct Roles of RNA Helicases MVH and TDRD9 in PIWI Slicing-Triggered Mammalian piRNA Biogenesis and Function.
Volume: 41
Issue: 6
Pages: 623-637.e9
Strain
Attribute String: coisogenic, mutant strain, transgenic
Allele
Name: DEAD box helicase 4; targeted mutation 1.1, David C Page
Allele Type: Targeted
Attribute String: Recombinase
Strain
Attribute String: targeted mutation, mutant strain, congenic
Strain
Attribute String: coisogenic, mutant strain, targeted mutation
Genotype
Symbol: Stk36/Stk36 Tg(Ddx4-cre)1Ptch/?
Background: involves: 129P2/OlaHsd
Zygosity: cn
Has Mutant Allele: true
Allele
Name: transgene insertion 1, Diego H Castrillon
Allele Type: Transgenic
Attribute String: Null/knockout, Recombinase
Publication
First Author: Huang L
Year: 2016
Journal: Oncotarget
Title: Rad9a is required for spermatogonia differentiation in mice.
Volume: 7
Issue: 52
Pages: 86350-86358
Genotype
Symbol: Ddx4/Ddx4<+> Rb1/Rb1
Background: involves: 129S4/SvJae * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Strain
Attribute String: coisogenic, mutant strain, transgenic
Strain
Attribute String: congenic, mutant strain, transgenic
Genotype
Symbol: Foxo3/Foxo3 Tg(Ddx4-cre/ERT2)1Dcas/?
Background: involves: 129S6/SvEvTac * FVB/N
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Lin Z
Year: 2017
Journal: Cell Res
Title: Mettl3-/Mettl14-mediated mRNA N6-methyladenosine modulates murine spermatogenesis.
Volume: 27
Issue: 10
Pages: 1216-1230
Publication
First Author: Miao H
Year: 2016
Journal: Mol Reprod Dev
Title: FOXJ2 controls meiosis during spermatogenesis in male mice.
Volume: 83
Issue: 8
Pages: 684-91
Publication
First Author: Yang QE
Year: 2015
Journal: PLoS Genet
Title: Inactivation of Retinoblastoma Protein (Rb1) in the Oocyte: Evidence That Dysregulated Follicle Growth Drives Ovarian Teratoma Formation in Mice.
Volume: 11
Issue: 7
Pages: e1005355
Publication
First Author: Kong F
Year: 2017
Journal: Cell Death Dis
Title: Differential regulation of spermatogenic process by Lkb1 isoforms in mouse testis.
Volume: 8
Issue: 10
Pages: e3121
Publication
First Author: Laronda MM
Year: 2011
Journal: Endocrinology
Title: Sox3 functions in a cell-autonomous manner to regulate spermatogonial differentiation in mice.
Volume: 152
Issue: 4
Pages: 1606-15
Publication
First Author: Tu Q
Year: 2018
Journal: Oncogene
Title: CDKN2B deletion is essential for pancreatic cancer development instead of unmeaningful co-deletion due to juxtaposition to CDKN2A.
Volume: 37
Issue: 1
Pages: 128-138
Publication
First Author: Huszar JM
Year: 2015
Journal: Reproduction
Title: Med1 regulates meiotic progression during spermatogenesis in mice.
Volume: 149
Issue: 6
Pages: 597-604
Publication
First Author: Zhang B
Year: 2020
Journal: Cell Death Differ
Title: NBS1 is required for SPO11-linked DNA double-strand break repair in male meiosis.
Volume: 27
Issue: 7
Pages: 2176-2190
Publication
First Author: Pellegrino J
Year: 2012
Journal: Dev Biol
Title: Chromatin associated Sin3A is essential for male germ cell lineage in the mouse.
Volume: 369
Issue: 2
Pages: 349-55
Publication
First Author: Yu J
Year: 2016
Journal: Development
Title: Protein synthesis and degradation are essential to regulate germline stem cell homeostasis in Drosophila testes.
Volume: 143
Issue: 16
Pages: 2930-45
Publication
First Author: Audouard C
Year: 2011
Journal: Fertil Steril
Title: Hsp90β1 knockout targeted to male germline: a mouse model for globozoospermia.
Volume: 95
Issue: 4
Pages: 1475-7.e1-4
Publication
First Author: Lambrot R
Year: 2015
Journal: FASEB J
Title: The histone demethylase KDM1A is essential for the maintenance and differentiation of spermatogonial stem cells and progenitors.
Volume: 29
Issue: 11
Pages: 4402-16
Publication
First Author: Abou Nader N
Year: 2019
Journal: Genesis
Title: Yes-associated protein expression in germ cells is dispensable for spermatogenesis in mice.
Volume: 57
Issue: 10
Pages: e23330
Publication
First Author: Lin Y
Year: 2020
Journal: Mol Cell
Title: eIF3 Associates with 80S Ribosomes to Promote Translation Elongation, Mitochondrial Homeostasis, and Muscle Health.
Volume: 79
Issue: 4
Pages: 575-587.e7
Publication
First Author: Wu YY
Year: 2015
Journal: Mol Reprod Dev
Title: Targeted disruption of the spermatid-specific gene Spata31 causes male infertility.
Volume: 82
Issue: 6
Pages: 432-40
Publication  
First Author: Diao F
Year: 2016
Journal: Sci Rep
Title: Alteration of protein prenylation promotes spermatogonial differentiation and exhausts spermatogonial stem cells in newborn mice.
Volume: 6
Pages: 28917
Publication  
First Author: Redgrove KA
Year: 2016
Journal: Sci Rep
Title: Dynamin 2 is essential for mammalian spermatogenesis.
Volume: 6
Pages: 35084
Publication
First Author: Liu HB
Year: 2019
Journal: Adv Sci (Weinh)
Title: RNA-Binding Protein IGF2BP2/IMP2 is a Critical Maternal Activator in Early Zygotic Genome Activation.
Volume: 6
Issue: 15
Pages: 1900295
Publication
First Author: Cheng EC
Year: 2021
Journal: Cell Rep
Title: The Essential Function of SETDB1 in Homologous Chromosome Pairing and Synapsis during Meiosis.
Volume: 34
Issue: 1
Pages: 108575
Publication
First Author: Serra ND
Year: 2017
Journal: Biol Reprod
Title: Cell-autonomous requirement for mammalian target of rapamycin (Mtor) in spermatogonial proliferation and differentiation in the mouse†.
Volume: 96
Issue: 4
Pages: 816-828
Publication
First Author: Bain CC
Year: 2017
Journal: Nat Commun
Title: TGFβR signalling controls CD103+CD11b+ dendritic cell development in the intestine.
Volume: 8
Issue: 1
Pages: 620
Publication
First Author: Jiang G
Year: 2020
Journal: J Immunol
Title: Tob2 Inhibits TLR-Induced Inflammatory Responses by Association with TRAF6 and MyD88.
Volume: 205
Issue: 4
Pages: 981-986
Publication
First Author: Zhang H
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Experimental evidence showing that no mitotically active female germline progenitors exist in postnatal mouse ovaries.
Volume: 109
Issue: 31
Pages: 12580-5
Publication  
First Author: He Z
Year: 2020
Journal: Genes (Basel)
Title: Ring 1 and YY1 Binding Protein Expressed in Murine Spermatocytes but Dispensable for Spermatogenesis.
Volume: 11
Issue: 1
Publication
First Author: Ma P
Year: 2020
Journal: J Mol Cell Biol
Title: ZC4H2 stabilizes RNF220 to pattern ventral spinal cord through modulating Shh/Gli signaling.
Volume: 12
Issue: 5
Pages: 337-344
Publication
First Author: Ma P
Year: 2019
Journal: Cell Rep
Title: Fine-Tuning of Shh/Gli Signaling Gradient by Non-proteolytic Ubiquitination during Neural Patterning.
Volume: 28
Issue: 2
Pages: 541-553.e4
Publication
First Author: Wang M
Year: 2017
Journal: Mol Cell Proteomics
Title: The Glial Cell-Derived Neurotrophic Factor (GDNF)-responsive Phosphoprotein Landscape Identifies Raptor Phosphorylation Required for Spermatogonial Progenitor Cell Proliferation.
Volume: 16
Issue: 6
Pages: 982-997
Publication
First Author: Tong MH
Year: 2012
Journal: Biol Reprod
Title: Two miRNA clusters, Mir-17-92 (Mirc1) and Mir-106b-25 (Mirc3), are involved in the regulation of spermatogonial differentiation in mice.
Volume: 86
Issue: 3
Pages: 72
Publication
First Author: Fok KL
Year: 2017
Journal: Endocrinology
Title: Huwe1 Regulates the Establishment and Maintenance of Spermatogonia by Suppressing DNA Damage Response.
Volume: 158
Issue: 11
Pages: 4000-4016
Publication
First Author: Serra N
Year: 2019
Journal: Biol Reprod
Title: The mTORC1 component RPTOR is required for maintenance of the foundational spermatogonial stem cell pool in mice†.
Volume: 100
Issue: 2
Pages: 429-439
Publication  
First Author: Wang M
Year: 2020
Journal: J Cell Sci
Title: LIN28A binds to meiotic gene transcripts and modulates their translation in male germ cells.
Volume: 133
Issue: 12
Publication
First Author: Kishi K
Year: 2017
Journal: Reproduction
Title: Spermatogonial deubiquitinase USP9X is essential for proper spermatogenesis in mice.
Volume: 154
Issue: 2
Pages: 135-143
Publication
First Author: Xia X
Year: 2019
Journal: Cell Death Dis
Title: Germline deletion of Cdyl causes teratozoospermia and progressive infertility in male mice.
Volume: 10
Issue: 3
Pages: 229
Publication
First Author: Wen J
Year: 2019
Journal: BMC Biol
Title: GSK-3β protects fetal oocytes from premature death via modulating TAp63 expression in mice.
Volume: 17
Issue: 1
Pages: 23
Publication
First Author: Jiang C
Year: 2017
Journal: PLoS Genet
Title: GGPP-Mediated Protein Geranylgeranylation in Oocyte Is Essential for the Establishment of Oocyte-Granulosa Cell Communication and Primary-Secondary Follicle Transition in Mouse Ovary.
Volume: 13
Issue: 1
Pages: e1006535
Genotype
Symbol: Tg(Ddx4-cre)1Dcas/? Tg(EIF1AX-Lin28a)#Gqda/?
Background: involves: 129S4/SvJae * C57BL/6 * CD-1 * FVB/N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Bscl2/Bscl2 Tg(Ddx4-cre)1Dcas/?
Background: involves: 129 * 129S4/SvJaeSor * FVB/N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Spata31/Spata31 Tg(Ddx4-cre)1Dcas/?
Background: involves: 129S7/SvEvBrd * FVB
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(Ddx4-cre)1Dcas/? Rnf220/Rnf220
Background: involves: C57BL/6 * FVB
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tsc22d3/? Tg(Ddx4-cre)1Dcas/?
Background: involves: C57BL/6 * FVB
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(Ddx4-cre)1Dcas/? Uxt/?
Background: involves: 129S1/Sv * C57BL/6 * FVB
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Skp1/Skp1 Tg(Ddx4-cre/ERT2)1Dcas/?
Background: involves: 129S4/SvJae * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tsc22d3/? Tg(Ddx4-cre)1Dcas/?
Background: involves: 129S1/SvImJ * C57BL/6N * FVB
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Mettl3/Mettl3 Tg(Ddx4-cre)1Dcas/?
Background: involves: C57BL/6J * FVB
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Mettl14/Mettl14 Tg(Ddx4-cre)1Dcas/?
Background: involves: C57BL/6J * FVB
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Foxj2/Foxj2 Tg(Ddx4-cre)1Dcas/?
Background: involves: FVB
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Hsp90b1/Hsp90b1 Tg(Ddx4-cre)1Dcas/?
Background: involves: 129S/SvEv * FVB
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Foxo3/Foxo3 Tg(Ddx4-cre)1Dcas/?
Background: involves: 129S6/SvEvTac * FVB/N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Mettl3/Mettl3 Mettl14/Mettl14 Tg(Ddx4-cre)1Dcas/?
Background: involves: C57BL/6J * FVB
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Pten/Pten Tg(Ddx4-cre/ERT2)1Dcas/?
Background: involves: 129S4/SvJae * FVB/N
Zygosity: cn
Has Mutant Allele: true