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Search results 1 to 100 out of 109 for Dlgap1

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Domain
Type: Family
Description: Disks large-associated protein 1, also known as GKAP or DAP-1, is a member of the SAPAP family. It is a synaptic protein that may play several roles in the molecular organisation of synapses and neuronal cell signalling [, ]. It has been linked to obsessive-compulsive disorder (OCD) [].SAPAP family members are PSD-95/SAP90-associated proteins localised at postsynaptic density []. Postsynaptic density (PSD) is a specialised submembranous structure within which synaptic membrane proteins are linked to cytoskeletonand signalling proteins. PSD-95/SAP90 is one of the major components of PSD, and functions as a scaffold protein for various ion channels and associated signalling molecules.
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Publication
First Author: Coba MP
Year: 2018
Journal: Sci Rep
Title: Dlgap1 knockout mice exhibit alterations of the postsynaptic density and selective reductions in sociability.
Volume: 8
Issue: 1
Pages: 2281
Publication
First Author: Zhang J
Year: 2020
Journal: Lipids Health Dis
Title: Dlgap1 negatively regulates browning of white fat cells through effects on cell proliferation and apoptosis.
Volume: 19
Issue: 1
Pages: 39
Protein
Organism: Mus musculus/domesticus
Length: 992  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 535  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 699  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 944  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 692  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 982  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 726  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 666  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 682  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 660  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 636  
Fragment?: false
Publication
First Author: Kim E
Year: 1997
Journal: J Cell Biol
Title: GKAP, a novel synaptic protein that interacts with the guanylate kinase-like domain of the PSD-95/SAP90 family of channel clustering molecules.
Volume: 136
Issue: 3
Pages: 669-78
Publication
First Author: Satoh K
Year: 1997
Journal: Genes Cells
Title: DAP-1, a novel protein that interacts with the guanylate kinase-like domains of hDLG and PSD-95.
Volume: 2
Issue: 6
Pages: 415-24
Publication
First Author: Mattheisen M
Year: 2015
Journal: Mol Psychiatry
Title: Genome-wide association study in obsessive-compulsive disorder: results from the OCGAS.
Volume: 20
Issue: 3
Pages: 337-44
Publication
First Author: Takeuchi M
Year: 1997
Journal: J Biol Chem
Title: SAPAPs. A family of PSD-95/SAP90-associated proteins localized at postsynaptic density.
Volume: 272
Issue: 18
Pages: 11943-51
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Ehlers MD
Year: 1999
Journal: Curr Biol
Title: Synapse structure: glutamate receptors connected by the shanks.
Volume: 9
Issue: 22
Pages: R848-50
GXD Expression    
Probe: MGI:4428843
Assay Type: RNA in situ
Annotation Date: 2023-09-26
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7530860
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:5287868
Assay Type: Immunohistochemistry
Annotation Date: 2011-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284526
Pattern: Punctate
Stage: TS26
Assay Id: MGI:5287899
Age: embryonic day 18.0
Image: 2i
Note: Expression is concentrated at synapses.
Specimen Label: 2i
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:5287868
Assay Type: Immunohistochemistry
Annotation Date: 2011-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284526
Pattern: Punctate
Stage: TS26
Assay Id: MGI:5287899
Age: embryonic day 18.0
Image: 2o
Note: Expression is concentrated at synapses and is the same as in wild-type.
Specimen Label: 2o
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:5287868
Assay Type: Immunohistochemistry
Annotation Date: 2011-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284528
Pattern: Punctate
Stage: TS28
Assay Id: MGI:5287899
Age: postnatal adult
Image: 2c
Note: Expression is concentrated at synapses.
Specimen Label: 2c
Detected: true
Specimen Num: 1
Publication
First Author: Parker MJ
Year: 2004
Journal: J Neurosci
Title: PSD93 regulates synaptic stability at neuronal cholinergic synapses.
Volume: 24
Issue: 2
Pages: 378-88
Publication
First Author: Baud A
Year: 2021
Journal: Genome Biol
Title: Dissecting indirect genetic effects from peers in laboratory mice.
Volume: 22
Issue: 1
Pages: 216
Publication
First Author: Moutin E
Year: 2012
Journal: J Cell Sci
Title: GKAP-DLC2 interaction organizes the postsynaptic scaffold complex to enhance synaptic NMDA receptor activity.
Volume: 125
Issue: Pt 8
Pages: 2030-40
Publication
First Author: Welch JM
Year: 2004
Journal: J Comp Neurol
Title: Differential mRNA expression and protein localization of the SAP90/PSD-95-associated proteins (SAPAPs) in the nervous system of the mouse.
Volume: 472
Issue: 1
Pages: 24-39
Publication
First Author: Horner AE
Year: 2021
Journal: Genes Brain Behav
Title: Learning and reaction times in mouse touchscreen tests are differentially impacted by mutations in genes encoding postsynaptic interacting proteins SYNGAP1, NLGN3, DLGAP1, DLGAP2 and SHANK2.
Volume: 20
Issue: 1
Pages: e12723
Publication
First Author: Naim E
Year: 2005
Journal: Kidney Int
Title: Mutagenesis of the epithelial polarity gene, discs large 1, perturbs nephrogenesis in the developing mouse kidney.
Volume: 68
Issue: 3
Pages: 955-65
Publication
First Author: Wang X
Year: 2011
Journal: Hum Mol Genet
Title: Synaptic dysfunction and abnormal behaviors in mice lacking major isoforms of Shank3.
Volume: 20
Issue: 15
Pages: 3093-108
Publication
First Author: Schütt J
Year: 2009
Journal: J Biol Chem
Title: Fragile X mental retardation protein regulates the levels of scaffold proteins and glutamate receptors in postsynaptic densities.
Volume: 284
Issue: 38
Pages: 25479-87
Publication
First Author: Serpinskaya AS
Year: 1999
Journal: Dev Biol
Title: Synapse formation by hippocampal neurons from agrin-deficient mice.
Volume: 205
Issue: 1
Pages: 65-78
Publication
First Author: Boon AC
Year: 2009
Journal: J Virol
Title: Host genetic variation affects resistance to infection with a highly pathogenic H5N1 influenza A virus in mice.
Volume: 83
Issue: 20
Pages: 10417-26
Publication
First Author: Verpelli C
Year: 2011
Journal: J Biol Chem
Title: Importance of Shank3 protein in regulating metabotropic glutamate receptor 5 (mGluR5) expression and signaling at synapses.
Volume: 286
Issue: 40
Pages: 34839-50
Publication  
First Author: Lie E
Year: 2016
Journal: Nat Commun
Title: SALM4 suppresses excitatory synapse development by cis-inhibiting trans-synaptic SALM3-LAR adhesion.
Volume: 7
Pages: 12328
Publication
First Author: Sawallisch C
Year: 2009
Journal: J Biol Chem
Title: The insulin receptor substrate of 53 kDa (IRSp53) limits hippocampal synaptic plasticity.
Volume: 284
Issue: 14
Pages: 9225-36
Publication
First Author: Li J
Year: 2017
Journal: Nat Neurosci
Title: Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.
Volume: 20
Issue: 8
Pages: 1150-1161
Publication
First Author: Munton RP
Year: 2007
Journal: Mol Cell Proteomics
Title: Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.
Volume: 6
Issue: 2
Pages: 283-93
Publication
First Author: Bouwman J
Year: 2006
Journal: J Neurochem
Title: Reduced expression of neuropeptide genes in a genome-wide screen of a secretion-deficient mouse.
Volume: 99
Issue: 1
Pages: 84-96
Publication
First Author: Brady KP
Year: 1997
Journal: Genome Res
Title: Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis.
Volume: 7
Issue: 11
Pages: 1085-93
Publication      
First Author: The Jackson Laboratory Backcross DNA Panel Mapping Resource
Year: 1999
Journal: Database Release
Title: JAX BSS Panel Mapping Data
Publication      
First Author: MGI and IMPC
Year: 2017
Journal: MGI Direct Data Submission
Title: MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Mouse Synonym Curation
Publication
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
Publication  
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication        
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform