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Search results 1 to 100 out of 248 for Dock2

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Hits by Pathway

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Hits by Strain

Type Details Score
Gene
1794 | DOCK2
Type: gene
Organism: human
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Gene
100497849 | dock2
Type: gene
Organism: frog, western clawed
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Gene
360509 | Dock2
Type: gene
Organism: rat
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Gene
489128 | DOCK2
Type: gene
Organism: dog, domestic
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Gene
471731 | DOCK2
Type: gene
Organism: chimpanzee
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Gene
510083 | DOCK2
Type: gene
Organism: cattle
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Gene
427612 | DOCK2
Type: gene
Organism: chicken
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Gene
100330200 | dock2
Type: gene
Organism: zebrafish
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Gene
704061 | DOCK2
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:2149010 | Dock2
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
148904219 | DOCK2-AS1
Type: gene
Organism: human
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Publication
18157938 | J:130919
First Author: Kikuchi T
Year: 2008
Journal: Biochem Biophys Res Commun
Title: Dock2 participates in bone marrow lympho-hematopoiesis.
Volume: 367
Issue: 1
Pages: 90-6
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Publication
16772603 | J:139472
First Author: Shulman Z
Year: 2006
Journal: Blood
Title: DOCK2 regulates chemokine-triggered lateral lymphocyte motility but not transendothelial migration.
Volume: 108
Issue: 7
Pages: 2150-8
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Publication
37021575 | J:364343
First Author: Guo X
Year: 2023
Journal: Arterioscler Thromb Vasc Biol
Title: DOCK2 Deficiency Attenuates Abdominal Aortic Aneurysm Formation-Brief Report.
Volume: 43
Issue: 6
Pages: e210-e217
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Publication
37838011 | J:367879
First Author: Qian G
Year: 2024
Journal: Am J Pathol
Title: DOCK2 Promotes Atherosclerosis by Mediating the Endothelial Cell Inflammatory Response.
Volume: 194
Issue: 4
Pages: 599-611
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Publication
36804596 | J:335036
First Author: Kunimura K
Year: 2023
Journal: J Allergy Clin Immunol
Title: DOCK2 regulates MRGPRX2/B2-mediated mast cell degranulation and drug-induced anaphylaxis.
Volume: 151
Issue: 6
Pages: 1585-1594.e9
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Publication
19728314 | J:153767
First Author: Lei Y
Year: 2009
Journal: Eur J Immunol
Title: Role of DOCK2 and DOCK180 in fetal thymus colonization.
Volume: 39
Issue: 10
Pages: 2695-702
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Publication
34710342 | J:368125
First Author: Qian G
Year: 2022
Journal: Am J Respir Cell Mol Biol
Title: DOCK2 Promotes Pleural Fibrosis by Modulating Mesothelial to Mesenchymal Transition.
Volume: 66
Issue: 2
Pages: 171-182
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Publication
27291827 | J:272301
 
First Author: Liu Z
Year: 2016
Journal: Sci Rep
Title: DOCK2 confers immunity and intestinal colonization resistance to Citrobacter rodentium infection.
Volume: 6
Pages: 27814
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Publication
23050005 | J:225079
First Author: Terasawa M
Year: 2012
Journal: PLoS One
Title: Dimerization of DOCK2 is essential for DOCK2-mediated Rac activation and lymphocyte migration.
Volume: 7
Issue: 9
Pages: e46277
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Publication
15357953 | J:93926
First Author: Nombela-Arrieta C
Year: 2004
Journal: Immunity
Title: Differential requirements for DOCK2 and phosphoinositide-3-kinase gamma during T and B lymphocyte homing.
Volume: 21
Issue: 3
Pages: 429-41
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Publication
29503648 | J:265011
 
First Author: Ushijima M
Year: 2018
Journal: Front Immunol
Title: The Rac Activator DOCK2 Mediates Plasma Cell Differentiation and IgG Antibody Production.
Volume: 9
Pages: 243
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Publication
38366567 | J:370479
First Author: Randall KL
Year: 2024
Journal: J Infect Dis
Title: DOCK2 Deficiency Causes Defects in Antiviral T-Cell Responses and Impaired Control of Herpes Simplex Virus Infection.
Volume: 230
Issue: 3
Pages: e712-e721
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Publication
11518968 | J:71005
First Author: Fukui Y
Year: 2001
Journal: Nature
Title: Haematopoietic cell-specific CDM family protein DOCK2 is essential for lymphocyte migration.
Volume: 412
Issue: 6849
Pages: 826-31
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Publication
28716822 | J:245399
First Author: Guo X
Year: 2017
Journal: J Lipid Res
Title: DOCK2 deficiency mitigates HFD-induced obesity by reducing adipose tissue inflammation and increasing energy expenditure.
Volume: 58
Issue: 9
Pages: 1777-1784
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Publication
16943182 | J:113266
First Author: Kunisaki Y
Year: 2006
Journal: J Cell Biol
Title: DOCK2 is a Rac activator that regulates motility and polarity during neutrophil chemotaxis.
Volume: 174
Issue: 5
Pages: 647-52
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Publication
30065028 | J:283850
 
First Author: Sakurai T
Year: 2018
Journal: Sci Signal
Title: Cholesterol sulfate is a DOCK2 inhibitor that mediates tissue-specific immune evasion in the eye.
Volume: 11
Issue: 541
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Publication
17325199 | J:125362
First Author: Nombela-Arrieta C
Year: 2007
Journal: J Exp Med
Title: A central role for DOCK2 during interstitial lymphocyte motility and sphingosine-1-phosphate-mediated egress.
Volume: 204
Issue: 3
Pages: 497-510
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Publication
16585555 | J:131163
First Author: Kunisaki Y
Year: 2006
Journal: J Immunol
Title: DOCK2 is required in T cell precursors for development of Valpha14 NK T cells.
Volume: 176
Issue: 8
Pages: 4640-5
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Publication
37383235 | J:346951
 
First Author: Machin PA
Year: 2023
Journal: Front Immunol
Title: Dock2 generates characteristic spatiotemporal patterns of Rac activity to regulate neutrophil polarisation, migration and phagocytosis.
Volume: 14
Pages: 1180886
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Publication
23719299 | J:201343
First Author: Sakai Y
Year: 2013
Journal: Blood
Title: The Rac activator DOCK2 regulates natural killer cell-mediated cytotoxicity in mice through the lytic synapse formation.
Volume: 122
Issue: 3
Pages: 386-93
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Publication
12871644 | J:84581
First Author: Sanui T
Year: 2003
Journal: Immunity
Title: DOCK2 is essential for antigen-induced translocation of TCR and lipid rafts, but not PKC-theta and LFA-1, in T cells.
Volume: 19
Issue: 1
Pages: 119-29
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Publication
19729484 | J:153055
First Author: Cimino PJ
Year: 2009
Journal: Am J Pathol
Title: DOCK2 is a microglial specific regulator of central nervous system innate immunity found in normal and Alzheimer's disease brain.
Volume: 175
Issue: 4
Pages: 1622-30
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Publication
31740487 | J:294302
First Author: Mahajan VS
Year: 2020
Journal: J Immunol
Title: DOCK2 Sets the Threshold for Entry into the Virtual Memory CD8(+) T Cell Compartment by Negatively Regulating Tonic TCR Triggering.
Volume: 204
Issue: 1
Pages: 49-57
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Publication
18198348 | J:132707
First Author: Gotoh K
Year: 2008
Journal: Blood
Title: Differential requirement for DOCK2 in migration of plasmacytoid dendritic cells versus myeloid dendritic cells.
Volume: 111
Issue: 6
Pages: 2973-6
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Publication
39242821 | J:357742
First Author: Churchhouse AMD
Year: 2024
Journal: Oncogene
Title: Loss of DOCK2 potentiates Inflammatory Bowel Disease-associated colorectal cancer via immune dysfunction and IFN? induction of IDO1 expression.
Volume: 43
Issue: 42
Pages: 3094-3107
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Publication
30012848 | J:264323
First Author: Wong SY
Year: 2018
Journal: J Immunol
Title: B Cell Defects Observed in Nod2 Knockout Mice Are a Consequence of a Dock2 Mutation Frequently Found in Inbred Strains.
Volume: 201
Issue: 5
Pages: 1442-1451
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Publication
22905357 | J:187712
First Author: Ippagunta SK
Year: 2012
Journal: Nat Immunol
Title: Addendum: defective Dock2 expression in a subset of ASC-deficient mouse lines.
Volume: 13
Issue: 7
Pages: 701-2
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Publication
20231379 | J:159178
First Author: Gotoh K
Year: 2010
Journal: J Exp Med
Title: Selective control of type I IFN induction by the Rac activator DOCK2 during TLR-mediated plasmacytoid dendritic cell activation.
Volume: 207
Issue: 4
Pages: 721-30
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Publication
22431588 | J:182658
First Author: Purtha WE
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Spontaneous mutation of the Dock2 gene in Irf5-/- mice complicates interpretation of type I interferon production and antibody responses.
Volume: 109
Issue: 15
Pages: E898-904
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Publication
- | J:274971
     
First Author: Choi JH
Year: 2019
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for Harborside.
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Publication
- | J:272403
     
First Author: Zhong X
Year: 2019
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for Landing.
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Publication
- | J:272405
     
First Author: Zhong X
Year: 2019
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for muelle.
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Publication
- | J:272437
     
First Author: Zhong X
Year: 2019
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for skiff.
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Publication
- | J:274942
     
First Author: Choi JH
Year: 2019
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for Wassup.
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Publication
- | J:272402
     
First Author: Zhong X
Year: 2019
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for pier.
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Publication
- | J:272404
     
First Author: Zhong X
Year: 2019
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for wharf.
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Publication
- | J:272406
     
First Author: Zhong X
Year: 2019
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for Slip.
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Publication
- | J:272438
     
First Author: Zhong X
Year: 2019
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for Launch.
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Publication
21892172 | J:176441
First Author: Ippagunta SK
Year: 2011
Journal: Nat Immunol
Title: The inflammasome adaptor ASC regulates the function of adaptive immune cells by controlling Dock2-mediated Rac activation and actin polymerization.
Volume: 12
Issue: 10
Pages: 1010-6
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Publication
27210752 | J:231437
First Author: Mahajan VS
Year: 2016
Journal: Cell Rep
Title: Striking Immune Phenotypes in Gene-Targeted Mice Are Driven by a Copy-Number Variant Originating from a Commercially Available C57BL/6 Strain.
Volume: 15
Issue: 9
Pages: 1901-9
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Publication
16230477 | J:116831
First Author: Jiang H
Year: 2005
Journal: J Exp Med
Title: Deletion of DOCK2, a regulator of the actin cytoskeleton in lymphocytes, suppresses cardiac allograft rejection.
Volume: 202
Issue: 8
Pages: 1121-30
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Publication
17767160 | J:125275
First Author: Tanaka Y
Year: 2007
Journal: Nat Immunol
Title: T helper type 2 differentiation and intracellular trafficking of the interleukin 4 receptor-alpha subunit controlled by the Rac activator Dock2.
Volume: 8
Issue: 10
Pages: 1067-75
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Publication
34767813 | J:331162
First Author: Qian G
Year: 2022
Journal: Am J Pathol
Title: Dedicator of Cytokinesis 2 (DOCK2) Deficiency Attenuates Lung Injury Associated with Chronic High-Fat and High-Fructose Diet-Induced Obesity.
Volume: 192
Issue: 2
Pages: 226-238
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Publication
37006281 | J:345243
 
First Author: Morino K
Year: 2023
Journal: Front Immunol
Title: Cholesterol sulfate limits neutrophil recruitment and gut inflammation during mucosal injury.
Volume: 14
Pages: 1131146
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Publication
28607113 | J:250891
First Author: Ackerknecht M
Year: 2017
Journal: J Immunol
Title: Antigen Availability and DOCK2-Driven Motility Govern CD4(+) T Cell Interactions with Dendritic Cells In Vivo.
Volume: 199
Issue: 2
Pages: 520-530
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Publication
25788409 | J:248973
First Author: Guo X
Year: 2015
Journal: Circ Res
Title: Dedicator of cytokinesis 2, a novel regulator for smooth muscle phenotypic modulation and vascular remodeling.
Volume: 116
Issue: 10
Pages: e71-80
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Publication
41181147 | J:375731
 
First Author: Morino K
Year: 2025
Journal: Front Immunol
Title: Sulfotransferase SULT2B1 contributes to the epithelial-immune microenvironment homeostasis in imiquimod-induced psoriatic dermatitis.
Volume: 16
Pages: 1632426
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Publication
41371223 | J:385846
First Author: Li X
Year: 2026
Journal: Immunity
Title: The TCR-SUB1-DOCK2 axis promotes autoimmunity by driving pathogenic CD4(+) T cell tissue infiltration.
Volume: 59
Issue: 1
Pages: 98-115.e8
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Publication
19451552 | J:150750
First Author: Gollmer K
Year: 2009
Journal: Blood
Title: CCL21 mediates CD4+ T-cell costimulation via a DOCK2/Rac-dependent pathway.
Volume: 114
Issue: 3
Pages: 580-8
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Publication
31405607 | J:293205
First Author: Jing Y
Year: 2019
Journal: J Allergy Clin Immunol
Title: Dedicator of cytokinesis protein 2 couples with lymphoid enhancer-binding factor 1 to regulate expression of CD21 and B-cell differentiation.
Volume: 144
Issue: 5
Pages: 1377-1390.e4
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Publication
23291967 | J:199969
First Author: Yasuda K
Year: 2013
Journal: Int Immunol
Title: Phenotype and function of B cells and dendritic cells from interferon regulatory factor 5-deficient mice with and without a mutation in DOCK2.
Volume: 25
Issue: 5
Pages: 295-306
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Publication
23975862 | J:205845
First Author: Pierini R
Year: 2013
Journal: J Immunol
Title: ASC controls IFN-? levels in an IL-18-dependent manner in caspase-1-deficient mice infected with Francisella novicida.
Volume: 191
Issue: 7
Pages: 3847-57
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Publication
24821968 | J:244219
First Author: Stevenson C
Year: 2014
Journal: J Immunol
Title: Essential role of Elmo1 in Dock2-dependent lymphocyte migration.
Volume: 192
Issue: 12
Pages: 6062-70
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Publication
25076492 | J:218999
First Author: Yasuda K
Year: 2014
Journal: PLoS One
Title: Interferon regulatory factor-5 deficiency ameliorates disease severity in the MRL/lpr mouse model of lupus in the absence of a mutation in DOCK2.
Volume: 9
Issue: 7
Pages: e103478
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Publication
25031348 | J:214624
First Author: Thackray LB
Year: 2014
Journal: J Virol
Title: Interferon regulatory factor 5-dependent immune responses in the draining lymph node protect against West Nile virus infection.
Volume: 88
Issue: 19
Pages: 11007-21
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Protein Coding Gene
MGP_CAROLIEiJ_G0016202 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
ENSMUSG00200006922 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00195007075 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00220003202 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00180001631 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00175003539 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2149010 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00215008994 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSTCUG00005027219 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00210006651 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00185009918 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00205010824 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00230002944 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSUMUG00000004549 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00190007190 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00225030483 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSLUMG00010016771 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSIUOG00005002016 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0017338 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
ENSMSPG00010002150 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
- | J:225938
     
First Author: Zeng M
Year: 2015
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for Arches
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Publication
- | J:255181
     
First Author: Yue T
Year: 2018
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for denali
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Publication
35844563 | J:332332
 
First Author: Pfenninger P
Year: 2022
Journal: Front Immunol
Title: Na?ve Primary Mouse CD8(+) T Cells Retain In Vivo Immune Responsiveness After Electroporation-Based CRISPR/Cas9 Genetic Engineering.
Volume: 13
Pages: 777113
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Publication
- | J:173592
     
First Author: Beutler B
Year: 2011
Journal: MGI Direct Data Submission
Title: Direct Data Submission 2011/07/15
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Publication
- | J:173670
     
First Author: Beutler B
Year: 2011
Journal: MGI Direct Data Submission
Title: Direct Data Submission 2011/07/19
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Publication
- | J:191187
   
First Author: Beutler B
Year: 2013
Journal: MGI Direct Data Submission
Title: Direct Data Submission
Volume: v
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Publication
- | J:221486
     
First Author: Zeng M
Year: 2015
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for liaoning
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Publication
- | J:236689
     
First Author: Yue T
Year: 2016
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for capitol_reef
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GXD Expression
GXD Expression
 
Probe: MGI:4885432
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691619
Pattern: Widespread
Stage: TS19
Assay Id: MGI:4945824
Age: embryonic day 11.5
Image: g01619 E11.5
Specimen Label: g01619 E11.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4885432
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691623
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945824
Age: embryonic day 15.5
Image: g01619 E15.5
Specimen Label: g01619 E15.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Assay Type: In situ reporter (knock in)
Annotation Date: 2023-02-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7438421
Age: postnatal
Specimen Label: 5A Spleen
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
       
Assay Type: In situ reporter (knock in)
Annotation Date: 2023-02-27
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:7438421
Age: postnatal
Specimen Label: 5A Kidney
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4885432
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284223
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945824
Age: embryonic day 15.5
Image: g01619 E15.5
Specimen Label: g01619 E15.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4885432
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267828
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945824
Age: postnatal day 7
Image: g01619 P7
Specimen Label: g01619 P7
Detected: true
Specimen Num: 3
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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