Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Publication |
First Author: |
Blasius AL |
Year: |
2009 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Mice with mutations of Dock7 have generalized hypopigmentation and white-spotting but show normal neurological function. |
Volume: |
106 |
Issue: |
8 |
Pages: |
2706-11 |
|
•
•
•
•
•
|
Publication |
First Author: |
Watabe-Uchida M |
Year: |
2006 |
Journal: |
Neuron |
Title: |
The Rac activator DOCK7 regulates neuronal polarity through local phosphorylation of stathmin/Op18. |
Volume: |
51 |
Issue: |
6 |
Pages: |
727-39 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yang YT |
Year: |
2012 |
Journal: |
Nat Neurosci |
Title: |
DOCK7 interacts with TACC3 to regulate interkinetic nuclear migration and cortical neurogenesis. |
Volume: |
15 |
Issue: |
9 |
Pages: |
1201-10 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nakamuta S |
Year: |
2017 |
Journal: |
J Cell Biol |
Title: |
Dual role for DOCK7 in tangential migration of interneuron precursors in the postnatal forebrain. |
Volume: |
216 |
Issue: |
12 |
Pages: |
4313-4330 |
|
•
•
•
•
•
|
Publication |
First Author: |
Le PT |
Year: |
2017 |
Journal: |
Bone |
Title: |
Spontaneous mutation of Dock7 results in lower trabecular bone mass and impaired periosteal expansion in aged female Misty mice. |
Volume: |
105 |
|
Pages: |
103-114 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bishop KA |
Year: |
2016 |
Journal: |
G3 (Bethesda) |
Title: |
CRISPR/Cas9-Mediated Insertion of loxP Sites in the Mouse Dock7 Gene Provides an Effective Alternative to Use of Targeted Embryonic Stem Cells. |
Volume: |
6 |
Issue: |
7 |
Pages: |
2051-61 |
|
•
•
•
•
•
|
Publication |
First Author: |
Motyl KJ |
Year: |
2013 |
Journal: |
J Bone Miner Res |
Title: |
Altered thermogenesis and impaired bone remodeling in Misty mice. |
Volume: |
28 |
Issue: |
9 |
Pages: |
1885-97 |
|
•
•
•
•
•
|
Publication |
First Author: |
Woolley GW |
Year: |
1941 |
Journal: |
Am Naturalist |
Title: |
"Misty," a new coat color dilution in the mouse, Mus musculus. |
Volume: |
75 |
|
Pages: |
507-508 |
|
•
•
•
•
•
|
Publication |
First Author: |
Corbin KL |
Year: |
2016 |
Journal: |
Endocrinology |
Title: |
Islet Hypersensitivity to Glucose Is Associated With Disrupted Oscillations and Increased Impact of Proinflammatory Cytokines in Islets From Diabetes-Prone Male Mice. |
Volume: |
157 |
Issue: |
5 |
Pages: |
1826-38 |
|
•
•
•
•
•
|
Publication |
First Author: |
Truett GE |
Year: |
1998 |
Journal: |
Am J Physiol |
Title: |
Misty (m) affects growth traits. |
Volume: |
275 |
Issue: |
1 Pt 2 |
Pages: |
R29-32 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sviderskaya EV |
Year: |
1998 |
Journal: |
Genetics |
Title: |
The murine misty mutation: phenotypic effects on melanocytes, platelets and brown fat. |
Volume: |
148 |
Issue: |
1 |
Pages: |
381-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Olmsted-Davis E |
Year: |
2007 |
Journal: |
Am J Pathol |
Title: |
Hypoxic adipocytes pattern early heterotopic bone formation. |
Volume: |
170 |
Issue: |
2 |
Pages: |
620-32 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tai Y |
Year: |
2014 |
Journal: |
Cell Rep |
Title: |
Regulation of chandelier cell cartridge and bouton development via DOCK7-mediated ErbB4 activation. |
Volume: |
6 |
Issue: |
2 |
Pages: |
254-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Woolley GW |
Year: |
1945 |
Journal: |
J Hered |
Title: |
Misty dilution in the mouse. |
Volume: |
36 |
Issue: |
9 |
Pages: |
269-70 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mayer L |
Year: |
2018 |
Journal: |
Blood |
Title: |
Nbeal2 interacts with Dock7, Sec16a, and Vac14. |
Volume: |
131 |
Issue: |
9 |
Pages: |
1000-1011 |
|
•
•
•
•
•
|
Publication |
First Author: |
Matoba K |
Year: |
2014 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
Rho-kinase regulation of TNF-α-induced nuclear translocation of NF-κB RelA/p65 and M-CSF expression via p38 MAPK in mesangial cells. |
Volume: |
307 |
Issue: |
5 |
Pages: |
F571-80 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shimoda M |
Year: |
2011 |
Journal: |
Diabetologia |
Title: |
The human glucagon-like peptide-1 analogue liraglutide preserves pancreatic beta cells via regulation of cell kinetics and suppression of oxidative and endoplasmic reticulum stress in a mouse model of diabetes. |
Volume: |
54 |
Issue: |
5 |
Pages: |
1098-108 |
|
•
•
•
•
•
|
Publication |
First Author: |
Maki T |
Year: |
2019 |
Journal: |
Sci Rep |
Title: |
Amelioration of diabetic nephropathy by SGLT2 inhibitors independent of its glucose-lowering effect: A possible role of SGLT2 in mesangial cells. |
Volume: |
9 |
Issue: |
1 |
Pages: |
4703 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhong X |
Year: |
2013 |
Journal: |
Diabetologia |
Title: |
miR-21 is a key therapeutic target for renal injury in a mouse model of type 2 diabetes. |
Volume: |
56 |
Issue: |
3 |
Pages: |
663-74 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kanda Y |
Year: |
2010 |
Journal: |
Am J Physiol Endocrinol Metab |
Title: |
Molecular mechanism by which pioglitazone preserves pancreatic beta-cells in obese diabetic mice: evidence for acute and chronic actions as a PPARgamma agonist. |
Volume: |
298 |
Issue: |
2 |
Pages: |
E278-86 |
|
•
•
•
•
•
|
Publication |
First Author: |
Davey JR |
Year: |
2020 |
Journal: |
FASEB J |
Title: |
Intravascular Follistatin gene delivery improves glycemic control in a mouse model of type 2 diabetes. |
Volume: |
34 |
Issue: |
4 |
Pages: |
5697-5714 |
|
•
•
•
•
•
|
Publication |
First Author: |
Duarte DA |
Year: |
2016 |
Journal: |
PLoS One |
Title: |
Conditioned Medium from Early-Outgrowth Bone Marrow Cells Is Retinal Protective in Experimental Model of Diabetes. |
Volume: |
11 |
Issue: |
2 |
Pages: |
e0147978 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pu D |
Year: |
2018 |
Journal: |
Neuroscience |
Title: |
Protective Effects of Sulforaphane on Cognitive Impairments and AD-like Lesions in Diabetic Mice are Associated with the Upregulation of Nrf2 Transcription Activity. |
Volume: |
381 |
|
Pages: |
35-45 |
|
•
•
•
•
•
|
Publication |
First Author: |
Calcutt NA |
Year: |
2017 |
Journal: |
J Clin Invest |
Title: |
Selective antagonism of muscarinic receptors is neuroprotective in peripheral neuropathy. |
Volume: |
127 |
Issue: |
2 |
Pages: |
608-622 |
|
•
•
•
•
•
|
Publication |
First Author: |
Alipio Z |
Year: |
2010 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Reversal of hyperglycemia in diabetic mouse models using induced-pluripotent stem (iPS)-derived pancreatic beta-like cells. |
Volume: |
107 |
Issue: |
30 |
Pages: |
13426-31 |
|
•
•
•
•
•
|
Publication |
First Author: |
Egozi A |
Year: |
2020 |
Journal: |
Cell Rep |
Title: |
Zonation of Pancreatic Acinar Cells in Diabetic Mice. |
Volume: |
32 |
Issue: |
7 |
Pages: |
108043 |
|
•
•
•
•
•
|
Publication |
First Author: |
Park CW |
Year: |
2009 |
Journal: |
Diabetes |
Title: |
Vascular endothelial growth factor inhibition by dRK6 causes endothelial apoptosis, fibrosis, and inflammation in the heart via the Akt/eNOS axis in db/db mice. |
Volume: |
58 |
Issue: |
11 |
Pages: |
2666-76 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ma D |
Year: |
2019 |
Journal: |
Brain Res |
Title: |
Long-term liraglutide ameliorates nigrostriatal impairment via regulating AMPK/PGC-1a signaling in diabetic mice. |
Volume: |
1714 |
|
Pages: |
126-132 |
|
•
•
•
•
•
|
Publication |
First Author: |
San MartÃn A |
Year: |
2007 |
Journal: |
Am J Physiol Heart Circ Physiol |
Title: |
Reactive oxygen species-selective regulation of aortic inflammatory gene expression in Type 2 diabetes. |
Volume: |
292 |
Issue: |
5 |
Pages: |
H2073-82 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jung YJ |
Year: |
2012 |
Journal: |
Biochem Biophys Res Commun |
Title: |
The effects of designed angiopoietin-1 variant on lipid droplet diameter, vascular endothelial cell density and metabolic parameters in diabetic db/db mice. |
Volume: |
420 |
Issue: |
3 |
Pages: |
498-504 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zimmermann C |
Year: |
2012 |
Journal: |
Endocrinology |
Title: |
Prevention of diabetes in db/db mice by dietary soy is independent of isoflavone levels. |
Volume: |
153 |
Issue: |
11 |
Pages: |
5200-11 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bermudez DM |
Year: |
2011 |
Journal: |
Am J Pathol |
Title: |
Impaired biomechanical properties of diabetic skin implications in pathogenesis of diabetic wound complications. |
Volume: |
178 |
Issue: |
5 |
Pages: |
2215-23 |
|
•
•
•
•
•
|
Publication |
First Author: |
Eller P |
Year: |
2011 |
Journal: |
Am J Pathol |
Title: |
A murine model of phosphate nephropathy. |
Volume: |
178 |
Issue: |
5 |
Pages: |
1999-2006 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xu J |
Year: |
2012 |
Journal: |
Diabetes |
Title: |
The role of microRNA-146a in the pathogenesis of the diabetic wound-healing impairment: correction with mesenchymal stem cell treatment. |
Volume: |
61 |
Issue: |
11 |
Pages: |
2906-12 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tocchetti CG |
Year: |
2012 |
Journal: |
Diabetes |
Title: |
GSH or palmitate preserves mitochondrial energetic/redox balance, preventing mechanical dysfunction in metabolically challenged myocytes/hearts from type 2 diabetic mice. |
Volume: |
61 |
Issue: |
12 |
Pages: |
3094-105 |
|
•
•
•
•
•
|
Publication |
First Author: |
Neuhofer A |
Year: |
2013 |
Journal: |
Diabetes |
Title: |
Impaired local production of proresolving lipid mediators in obesity and 17-HDHA as a potential treatment for obesity-associated inflammation. |
Volume: |
62 |
Issue: |
6 |
Pages: |
1945-56 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yamamoto N |
Year: |
2012 |
Journal: |
J Neurochem |
Title: |
Brain insulin resistance accelerates Aβ fibrillogenesis by inducing GM1 ganglioside clustering in the presynaptic membranes. |
Volume: |
121 |
Issue: |
4 |
Pages: |
619-28 |
|
•
•
•
•
•
|
Publication |
First Author: |
Neschen S |
Year: |
2015 |
Journal: |
Diabetes |
Title: |
Metformin supports the antidiabetic effect of a sodium glucose cotransporter 2 inhibitor by suppressing endogenous glucose production in diabetic mice. |
Volume: |
64 |
Issue: |
1 |
Pages: |
284-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Loeffler I |
Year: |
2013 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
Erythropoietin ameliorates podocyte injury in advanced diabetic nephropathy in the db/db mouse. |
Volume: |
305 |
Issue: |
6 |
Pages: |
F911-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li Q |
Year: |
2019 |
Journal: |
Cell Rep |
Title: |
The Protein Phosphatase 1 Complex Is a Direct Target of AKT that Links Insulin Signaling to Hepatic Glycogen Deposition. |
Volume: |
28 |
Issue: |
13 |
Pages: |
3406-3422.e7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li M |
Year: |
2013 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
GC/TOFMS analysis of metabolites in serum and urine reveals metabolic perturbation of TCA cycle in db/db mice involved in diabetic nephropathy. |
Volume: |
304 |
Issue: |
11 |
Pages: |
F1317-24 |
|
•
•
•
•
•
|
Publication |
First Author: |
Do OH |
Year: |
2014 |
Journal: |
Diabetologia |
Title: |
The secretory deficit in islets from db/db mice is mainly due to a loss of responding beta cells. |
Volume: |
57 |
Issue: |
7 |
Pages: |
1400-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ekim Üstünel B |
Year: |
2016 |
Journal: |
Nat Commun |
Title: |
Control of diabetic hyperglycaemia and insulin resistance through TSC22D4. |
Volume: |
7 |
|
Pages: |
13267 |
|
•
•
•
•
•
|
Publication |
First Author: |
Syeda MM |
Year: |
2012 |
Journal: |
Am J Pathol |
Title: |
Prostaglandin transporter modulates wound healing in diabetes by regulating prostaglandin-induced angiogenesis. |
Volume: |
181 |
Issue: |
1 |
Pages: |
334-46 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chakroborty D |
Year: |
2016 |
Journal: |
Am J Pathol |
Title: |
Activation of Dopamine D1 Receptors in Dermal Fibroblasts Restores Vascular Endothelial Growth Factor-A Production by These Cells and Subsequent Angiogenesis in Diabetic Cutaneous Wound Tissues. |
Volume: |
186 |
Issue: |
9 |
Pages: |
2262-70 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mazagova M |
Year: |
2013 |
Journal: |
Am J Physiol Heart Circ Physiol |
Title: |
Growth differentiation factor 15 impairs aortic contractile and relaxing function through altered caveolar signaling of the endothelium. |
Volume: |
304 |
Issue: |
5 |
Pages: |
H709-18 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang Y |
Year: |
2018 |
Journal: |
Am J Pathol |
Title: |
Reversing CXCL10 Deficiency Ameliorates Kidney Disease in Diabetic Mice. |
Volume: |
188 |
Issue: |
12 |
Pages: |
2763-2773 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang H |
Year: |
2014 |
Journal: |
PLoS One |
Title: |
Involvement of KLF11 in hepatic glucose metabolism in mice via suppressing of PEPCK-C expression. |
Volume: |
9 |
Issue: |
2 |
Pages: |
e89552 |
|
•
•
•
•
•
|
Publication |
First Author: |
Flach RJ |
Year: |
2011 |
Journal: |
J Biol Chem |
Title: |
Loss of mitogen-activated protein kinase phosphatase-1 protects from hepatic steatosis by repression of cell death-inducing DNA fragmentation factor A (DFFA)-like effector C (CIDEC)/fat-specific protein 27. |
Volume: |
286 |
Issue: |
25 |
Pages: |
22195-202 |
|
•
•
•
•
•
|
Publication |
First Author: |
Velmurugan GV |
Year: |
2012 |
Journal: |
Am J Physiol Heart Circ Physiol |
Title: |
Calcium homeostasis in vascular smooth muscle cells is altered in type 2 diabetes by Bcl-2 protein modulation of InsP3R calcium release channels. |
Volume: |
302 |
Issue: |
1 |
Pages: |
H124-34 |
|
•
•
•
•
•
|
Publication |
First Author: |
Oba S |
Year: |
2018 |
Journal: |
Sci Rep |
Title: |
Aberrant DNA methylation of Tgfb1 in diabetic kidney mesangial cells. |
Volume: |
8 |
Issue: |
1 |
Pages: |
16338 |
|
•
•
•
•
•
|
Publication |
First Author: |
Akasaka Y |
Year: |
2010 |
Journal: |
Biochim Biophys Acta |
Title: |
Direct evidence for leptin-induced lipid oxidation independent of long-form leptin receptor. |
Volume: |
1801 |
Issue: |
10 |
Pages: |
1115-22 |
|
•
•
•
•
•
|
Publication |
First Author: |
O'Neill CM |
Year: |
2013 |
Journal: |
Endocrinology |
Title: |
Circulating levels of IL-1B+IL-6 cause ER stress and dysfunction in islets from prediabetic male mice. |
Volume: |
154 |
Issue: |
9 |
Pages: |
3077-88 |
|
•
•
•
•
•
|
Publication |
First Author: |
Velmurugan GV |
Year: |
2013 |
Journal: |
Cardiovasc Res |
Title: |
Defective Nrf2-dependent redox signalling contributes to microvascular dysfunction in type 2 diabetes. |
Volume: |
100 |
Issue: |
1 |
Pages: |
143-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gilbert RE |
Year: |
2015 |
Journal: |
Diabetologia |
Title: |
SIRT1 activation ameliorates hyperglycaemia by inducing a torpor-like state in an obese mouse model of type 2 diabetes. |
Volume: |
58 |
Issue: |
4 |
Pages: |
819-27 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pal D |
Year: |
2023 |
Journal: |
Nat Commun |
Title: |
Identification of a physiologic vasculogenic fibroblast state to achieve tissue repair. |
Volume: |
14 |
Issue: |
1 |
Pages: |
1129 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yamauchi J |
Year: |
2011 |
Journal: |
J Neurosci |
Title: |
The atypical Guanine-nucleotide exchange factor, dock7, negatively regulates schwann cell differentiation and myelination. |
Volume: |
31 |
Issue: |
35 |
Pages: |
12579-92 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hirukawa H |
Year: |
2015 |
Journal: |
Mol Cell Endocrinol |
Title: |
Combination of DPP-4 inhibitor and PPARγ agonist exerts protective effects on pancreatic β-cells in diabetic db/db mice through the augmentation of IRS-2 expression. |
Volume: |
413 |
|
Pages: |
49-60 |
|
•
•
•
•
•
|
Publication |
First Author: |
Campo GM |
Year: |
2010 |
Journal: |
Biochim Biophys Acta |
Title: |
High-molecular weight hyaluronan reduced renal PKC activation in genetically diabetic mice. |
Volume: |
1802 |
Issue: |
11 |
Pages: |
1118-30 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dhar M |
Year: |
2014 |
Journal: |
Mol Endocrinol |
Title: |
Leptin induces hippocampal synaptogenesis via CREB-regulated microRNA-132 suppression of p250GAP. |
Volume: |
28 |
Issue: |
7 |
Pages: |
1073-87 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nuno DW |
Year: |
2009 |
Journal: |
Am J Physiol Heart Circ Physiol |
Title: |
Sex-dependent differences in Rho activation contribute to contractile dysfunction in type 2 diabetic mice. |
Volume: |
297 |
Issue: |
4 |
Pages: |
H1469-77 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
314
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
22
|
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Yu B |
Year: |
2018 |
Journal: |
J Invest Dermatol |
Title: |
Glycoprotein Nonmelanoma Clone B Regulates the Crosstalk between Macrophages and Mesenchymal Stem Cells toward Wound Repair. |
Volume: |
138 |
Issue: |
1 |
Pages: |
219-227 |
|
•
•
•
•
•
|
Publication |
First Author: |
Abadir P |
Year: |
2018 |
Journal: |
J Invest Dermatol |
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Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
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Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
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