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Search results 1 to 100 out of 390 for Dpp4

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Hits by Pathway

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Hits by Category

Type Details Score
Gene
key_979902 | Dpp4
Type: gene
Organism: Not Specified
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Gene
1803 | DPP4
Type: gene
Organism: human
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Gene
281122 | DPP4
Type: gene
Organism: cattle
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Gene
424187 | DPP4
Type: gene
Organism: chicken
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Gene
100301982 | dpp4
Type: gene
Organism: zebrafish
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Gene
654491 | DPP4
Type: gene
Organism: macaque, rhesus
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Gene
548987 | dpp4
Type: gene
Organism: frog, western clawed
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Gene
key_19482 | DPP4
Type: gene
Organism: pig, domestic
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Gene
25253 | Dpp4
Type: gene
Organism: rat
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Gene
478767 | DPP4
Type: gene
Organism: dog, domestic
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Gene
459689 | DPP4
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:94919 | Dpp4
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
100131604 | DPP4-DT
Type: gene
Organism: human
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Gene
117152610 | LOC117152610
Type: gene
Organism: human
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Publication
27999105 | J:246156
First Author: Baumeier C
Year: 2017
Journal: Diabetes
Title: Hepatic DPP4 DNA Methylation Associates With Fatty Liver.
Volume: 66
Issue: 1
Pages: 25-35
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Publication
29562231 | J:261803
First Author: Ghorpade DS
Year: 2018
Journal: Nature
Title: Hepatocyte-secreted DPP4 in obesity promotes adipose inflammation and insulin resistance.
Volume: 555
Issue: 7698
Pages: 673-677
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Publication
29031724 | J:276201
First Author: Baumeier C
Year: 2017
Journal: Mol Metab
Title: Elevated hepatic DPP4 activity promotes insulin resistance and non-alcoholic fatty liver disease.
Volume: 6
Issue: 10
Pages: 1254-1263
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Publication
35190847 | J:326257
First Author: Patarrão RS
Year: 2022
Journal: Diabetologia
Title: Prediabetes blunts DPP4 genetic control of postprandial glycaemia and insulin secretion.
Volume: 65
Issue: 5
Pages: 861-871
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Publication
37216093 | J:338920
First Author: Fadzeyeva E
Year: 2023
Journal: iScience
Title: Pancreas-derived DPP4 is not essential for glucose homeostasis under metabolic stress.
Volume: 26
Issue: 5
Pages: 106748
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Publication
22936179 | J:208484
First Author: Zhong J
Year: 2013
Journal: Diabetes
Title: A potential role for dendritic cell/macrophage-expressing DPP4 in obesity-induced visceral inflammation.
Volume: 62
Issue: 1
Pages: 149-57
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Publication
28348219 | J:242025
First Author: Li K
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Mouse-adapted MERS coronavirus causes lethal lung disease in human DPP4 knockin mice.
Volume: 114
Issue: 15
Pages: E3119-E3128
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Publication
24970775 | J:221834
First Author: Sueyoshi R
Year: 2014
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Stimulation of intestinal growth and function with DPP4 inhibition in a mouse short bowel syndrome model.
Volume: 307
Issue: 4
Pages: G410-9
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Publication
31891536 | J:294756
First Author: Romacho T
Year: 2020
Journal: Am J Physiol Endocrinol Metab
Title: DPP4 deletion in adipose tissue improves hepatic insulin sensitivity in diet-induced obesity.
Volume: 318
Issue: 5
Pages: E590-E599
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Publication
32724076 | J:292324
First Author: Baggio LL
Year: 2020
Journal: Nat Commun
Title: Plasma levels of DPP4 activity and sDPP4 are dissociated from inflammation in mice and humans.
Volume: 11
Issue: 1
Pages: 3766
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Publication
30393019 | J:271886
First Author: Varin EM
Year: 2019
Journal: Cell Metab
Title: Circulating Levels of Soluble Dipeptidyl Peptidase-4 Are Dissociated from Inflammation and Induced by Enzymatic DPP4 Inhibition.
Volume: 29
Issue: 2
Pages: 320-334.e5
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Publication
30778250 | J:282542
First Author: Hollande C
Year: 2019
Journal: Nat Immunol
Title: Inhibition of the dipeptidyl peptidase DPP4 (CD26) reveals IL-33-dependent eosinophil-mediated control of tumor growth.
Volume: 20
Issue: 3
Pages: 257-264
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Gene
117152611 | LOC117152611
Type: gene
Organism: human
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Publication
28344320 | J:249417
First Author: O'Leary HA
Year: 2017
Journal: Leukemia
Title: DPP4 truncated GM-CSF and IL-3 manifest distinct receptor-binding and regulatory functions compared with their full-length forms.
Volume: 31
Issue: 11
Pages: 2468-2478
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Publication
36302455 | J:331591
 
First Author: Hui Y
Year: 2023
Journal: Metabolism
Title: Nonenzymatic function of DPP4 promotes diabetes-associated cognitive dysfunction through IGF-2R/PKA/SP1/ERp29/IP3R2 pathway-mediated impairment of Treg function and M1 microglia polarization.
Volume: 138
Pages: 155340
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Publication
29263883 | J:292834
 
First Author: Munster VJ
Year: 2017
Journal: NPJ Vaccines
Title: Protective efficacy of a novel simian adenovirus vaccine against lethal MERS-CoV challenge in a transgenic human DPP4 mouse model.
Volume: 2
Pages: 28
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Publication
29253907 | J:253675
First Author: Dingenouts CKE
Year: 2017
Journal: PLoS One
Title: Inhibiting DPP4 in a mouse model of HHT1 results in a shift towards regenerative macrophages and reduces fibrosis after myocardial infarction.
Volume: 12
Issue: 12
Pages: e0189805
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Publication
28447181 | J:327379
First Author: Ye Y
Year: 2017
Journal: Cardiovasc Drugs Ther
Title: SGLT-2 Inhibition with Dapagliflozin Reduces the Activation of the Nlrp3/ASC Inflammasome and Attenuates the Development of Diabetic Cardiomyopathy in Mice with Type 2 Diabetes. Further Augmentation of the Effects with Saxagliptin, a DPP4 Inhibitor.
Volume: 31
Issue: 2
Pages: 119-132
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Publication
30626685 | J:286321
 
First Author: Iwata-Yoshikawa N
Year: 2019
Journal: J Virol
Title: Acute Respiratory Infection in Human Dipeptidyl Peptidase 4-Transgenic Mice Infected with Middle East Respiratory Syndrome Coronavirus.
Volume: 93
Issue: 6
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Publication
27750111 | J:331809
 
First Author: Tai W
Year: 2016
Journal: Virology
Title: A recombinant receptor-binding domain of MERS-CoV in trimeric form protects human dipeptidyl peptidase 4 (hDPP4) transgenic mice from MERS-CoV infection.
Volume: 499
Pages: 375-382
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Publication
31883094 | J:285962
 
First Author: Leist SR
Year: 2020
Journal: Methods Mol Biol
Title: Genetically Engineering a Susceptible Mouse Model for MERS-CoV-Induced Acute Respiratory Distress Syndrome.
Volume: 2099
Pages: 137-159
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Publication
34686605 | J:315826
 
First Author: Gutiérrez-Álvarez J
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Middle East respiratory syndrome coronavirus vaccine based on a propagation-defective RNA replicon elicited sterilizing immunity in mice.
Volume: 118
Issue: 43
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Publication
36807138 | J:334151
First Author: Wang C
Year: 2023
Journal: Cell Rep
Title: Dipeptidylpeptidase 4 promotes survival and stemness of acute myeloid leukemia stem cells.
Volume: 42
Issue: 2
Pages: 112105
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Publication
31130102 | J:286329
First Author: Jia W
Year: 2019
Journal: Emerg Microbes Infect
Title: Single intranasal immunization with chimpanzee adenovirus-based vaccine induces sustained and protective immunity against MERS-CoV infection.
Volume: 8
Issue: 1
Pages: 760-772
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Publication
32265331 | J:287921
 
First Author: Li K
Year: 2020
Journal: mBio
Title: Single-Dose, Intranasal Immunization with Recombinant Parainfluenza Virus 5 Expressing Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Spike Protein Protects Mice from Fatal MERS-CoV Infection.
Volume: 11
Issue: 2
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Publication
32663193 | J:301915
 
First Author: Varin EM
Year: 2020
Journal: JCI Insight
Title: Hematopoietic cell- versus enterocyte-derived dipeptidyl peptidase-4 differentially regulates triglyceride excursion in mice.
Volume: 5
Issue: 16
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Publication
26672095 | J:246399
First Author: Mulvihill EE
Year: 2016
Journal: Diabetes
Title: Inhibition of Dipeptidyl Peptidase-4 Impairs Ventricular Function and Promotes Cardiac Fibrosis in High Fat-Fed Diabetic Mice.
Volume: 65
Issue: 3
Pages: 742-54
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Publication
7999781 | J:22092
First Author: Bernard AM
Year: 1994
Journal: Biochemistry
Title: Structure of the mouse dipeptidyl peptidase IV (CD26) gene.
Volume: 33
Issue: 50
Pages: 15204-14
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Publication
27795435 | J:238079
 
First Author: Coleman CM
Year: 2017
Journal: J Virol
Title: CD8+ T Cells and Macrophages Regulate Pathogenesis in a Mouse Model of Middle East Respiratory Syndrome.
Volume: 91
Issue: 1
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Publication
31350829 | J:292667
First Author: Soare A
Year: 2020
Journal: Arthritis Rheumatol
Title: Dipeptidylpeptidase 4 as a Marker of Activated Fibroblasts and a Potential Target for the Treatment of Fibrosis in Systemic Sclerosis.
Volume: 72
Issue: 1
Pages: 137-149
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Publication
32378471 | J:300104
First Author: Yuan L
Year: 2020
Journal: Emerg Microbes Infect
Title: Animal models for emerging coronavirus: progress and new insights.
Volume: 9
Issue: 1
Pages: 949-961
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Publication
26075911 | J:286233
First Author: Barreira da Silva R
Year: 2015
Journal: Nat Immunol
Title: Dipeptidylpeptidase 4 inhibition enhances lymphocyte trafficking, improving both naturally occurring tumor immunity and immunotherapy.
Volume: 16
Issue: 8
Pages: 850-8
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Publication
27839908 | J:251869
First Author: Mulvihill EE
Year: 2017
Journal: Cell Metab
Title: Cellular Sites and Mechanisms Linking Reduction of Dipeptidyl Peptidase-4 Activity to Control of Incretin Hormone Action and Glucose Homeostasis.
Volume: 25
Issue: 1
Pages: 152-165
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Publication
21177828 | J:173890
First Author: Kyle KA
Year: 2011
Journal: Endocrinology
Title: Differential effects of PPAR-{gamma} activation versus chemical or genetic reduction of DPP-4 activity on bone quality in mice.
Volume: 152
Issue: 2
Pages: 457-67
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Publication
34808238 | J:324750
First Author: Jussila AR
Year: 2022
Journal: J Invest Dermatol
Title: Skin Fibrosis and Recovery Is Dependent on Wnt Activation via DPP4.
Volume: 142
Issue: 6
Pages: 1597-1606.e9
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Publication
28759649 | J:246218
First Author: Earnest JT
Year: 2017
Journal: PLoS Pathog
Title: The tetraspanin CD9 facilitates MERS-coronavirus entry by scaffolding host cell receptors and proteases.
Volume: 13
Issue: 7
Pages: e1006546
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Publication
28963101 | J:317680
 
First Author: Piao L
Year: 2017
Journal: J Am Heart Assoc
Title: Chronic Psychological Stress Accelerates Vascular Senescence and Impairs Ischemia-Induced Neovascularization: The Role of Dipeptidyl Peptidase-4/Glucagon-Like Peptide-1-Adiponectin Axis.
Volume: 6
Issue: 10
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Publication
25056937 | J:317519
First Author: Nazarian A
Year: 2014
Journal: Mol Cell Proteomics
Title: Inhibition of circulating dipeptidyl peptidase 4 activity in patients with metastatic prostate cancer.
Volume: 13
Issue: 11
Pages: 3082-96
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Publication
30188931 | J:265523
First Author: Strathmann EA
Year: 2018
Journal: PLoS One
Title: Evaluation of potential effects of Plastin 3 overexpression and low-dose SMN-antisense oligonucleotides on putative biomarkers in spinal muscular atrophy mice.
Volume: 13
Issue: 9
Pages: e0203398
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Publication
32607866 | J:295349
First Author: Singh A
Year: 2020
Journal: Virol Sin
Title: A Comprehensive Review of Animal Models for Coronaviruses: SARS-CoV-2, SARS-CoV, and MERS-CoV.
Volume: 35
Issue: 3
Pages: 290-304
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Protein Coding Gene
MGP_CAROLIEiJ_G0023591 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0025769 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0025745 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0025715 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0025740 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0025501 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_94919 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0026187 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0024965 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0025481 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0025612 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0025574 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0025700 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0025605 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0026244 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0024706 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0025033 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0025042 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0024513 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
1370813 | J:1599
First Author: Marguet D
Year: 1992
Journal: J Biol Chem
Title: cDNA cloning for mouse thymocyte-activating molecule. A multifunctional ecto-dipeptidyl peptidase IV (CD26) included in a subgroup of serine proteases.
Volume: 267
Issue: 4
Pages: 2200-8
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Publication
28830941 | J:287147
 
First Author: Menachery VD
Year: 2017
Journal: mBio
Title: MERS-CoV Accessory ORFs Play Key Role for Infection and Pathogenesis.
Volume: 8
Issue: 4
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Publication
26124093 | J:223728
First Author: Pascal KE
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Pre- and postexposure efficacy of fully human antibodies against Spike protein in a novel humanized mouse model of MERS-CoV infection.
Volume: 112
Issue: 28
Pages: 8738-43
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Publication
31550243 | J:286238
 
First Author: Kulcsar KA
Year: 2019
Journal: JCI Insight
Title: Comorbid diabetes results in immune dysregulation and enhanced disease severity following MERS-CoV infection.
Volume: 4
Issue: 20
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Publication
36378534 | J:336029
 
First Author: Verma AK
Year: 2022
Journal: JCI Insight
Title: SARS-CoV-2 infection of sustentacular cells disrupts olfactory signaling pathways.
Volume: 7
Issue: 24
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Publication
37882568 | J:343780
First Author: Wong L-YR
Year: 2023
Journal: mBio
Title: Contrasting roles of MERS-CoV and SARS-CoV-2 internal proteins in pathogenesis in mice.
Volume: 14
Issue: 6
Pages: e0247623
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Publication
33144319 | J:300138
 
First Author: Gutierrez-Alvarez J
Year: 2021
Journal: J Virol
Title: Middle East Respiratory Syndrome Coronavirus Gene 5 Modulates Pathogenesis in Mice.
Volume: 95
Issue: 3
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Publication
27892925 | J:279834
 
First Author: Cockrell AS
Year: 2016
Journal: Nat Microbiol
Title: A mouse model for MERS coronavirus-induced acute respiratory distress syndrome.
Volume: 2
Pages: 16226
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Publication
29277291 | J:286198
 
First Author: Douglas MG
Year: 2018
Journal: Virology
Title: Adaptive evolution influences the infectious dose of MERS-CoV necessary to achieve severe respiratory disease.
Volume: 517
Pages: 98-107
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Publication
32253226 | J:286320
 
First Author: Sheahan TP
Year: 2020
Journal: Sci Transl Med
Title: An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice.
Volume: 12
Issue: 541
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Publication
31339932 | J:279723
First Author: Leist SR
Year: 2019
Journal: PLoS One
Title: Increasing the translation of mouse models of MERS coronavirus pathogenesis through kinetic hematological analysis.
Volume: 14
Issue: 7
Pages: e0220126
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Publication
10823914 | J:62709
First Author: Marguet D
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: Enhanced insulin secretion and improved glucose tolerance in mice lacking CD26.
Volume: 97
Issue: 12
Pages: 6874-9
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Publication
16712972 | J:110634
First Author: El Yacoubi M
Year: 2006
Journal: Behav Brain Res
Title: Behavioral characterization of CD26 deficient mice in animal tests of anxiety and antidepressant-like activity.
Volume: 171
Issue: 2
Pages: 279-85
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Publication
20828536 | J:165854
First Author: Takasawa W
Year: 2010
Journal: Biochem Biophys Res Commun
Title: Inhibition of dipeptidyl peptidase 4 regulates microvascular endothelial growth induced by inflammatory cytokines.
Volume: 401
Issue: 1
Pages: 7-12
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Publication
15310902 | J:92424
First Author: Christopherson KW 2nd
Year: 2004
Journal: Science
Title: Modulation of hematopoietic stem cell homing and engraftment by CD26.
Volume: 305
Issue: 5686
Pages: 1000-3
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Publication
26233333 | J:346589
First Author: Jang JH
Year: 2015
Journal: Clin Exp Metastasis
Title: Suppression of lung metastases by the CD26/DPP4 inhibitor Vildagliptin in mice.
Volume: 32
Issue: 7
Pages: 677-87
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Publication
22125312 | J:322966
First Author: Detel D
Year: 2012
Journal: Exp Physiol
Title: Development and resolution of colitis in mice with target deletion of dipeptidyl peptidase IV.
Volume: 97
Issue: 4
Pages: 486-96
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Publication
12778469 | J:83890
First Author: Yan S
Year: 2003
Journal: Eur J Immunol
Title: Deficiency of CD26 results in a change of cytokine and immunoglobulin secretion after stimulation by pokeweed mitogen.
Volume: 33
Issue: 6
Pages: 1519-27
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Publication
20097729 | J:164332
First Author: Sauvé M
Year: 2010
Journal: Diabetes
Title: Genetic deletion or pharmacological inhibition of dipeptidyl peptidase-4 improves cardiovascular outcomes after myocardial infarction in mice.
Volume: 59
Issue: 4
Pages: 1063-73
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Publication
21291952 | J:177968
First Author: Kidd S
Year: 2011
Journal: Exp Hematol
Title: In vivo expansion of the megakaryocyte progenitor cell population in adult CD26-deficient mice.
Volume: 39
Issue: 5
Pages: 580-590.e1
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Publication
19341621 | J:149843
First Author: Zaruba MM
Year: 2009
Journal: Cell Stem Cell
Title: Synergy between CD26/DPP-IV inhibition and G-CSF improves cardiac function after acute myocardial infarction.
Volume: 4
Issue: 4
Pages: 313-23
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Publication
12748388 | J:83610
First Author: Conarello SL
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Mice lacking dipeptidyl peptidase IV are protected against obesity and insulin resistance.
Volume: 100
Issue: 11
Pages: 6825-30
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Publication
17372022 | J:145134
First Author: Preller V
Year: 2007
Journal: J Immunol
Title: TGF-beta1-mediated control of central nervous system inflammation and autoimmunity through the inhibitory receptor CD26.
Volume: 178
Issue: 7
Pages: 4632-40
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Publication
30202822 | J:346519
First Author: Duarte N
Year: 2018
Journal: Hepatol Commun
Title: Dipeptidyl Peptidase-4 Is a Pro-Recovery Mediator During Acute Hepatotoxic Damage and Mirrors Severe Shifts in Kupffer Cells.
Volume: 2
Issue: 9
Pages: 1080-1094
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Publication
16154213 | J:104027
First Author: Guieu R
Year: 2006
Journal: Behav Brain Res
Title: CD26 modulates nociception in mice via its dipeptidyl-peptidase IV activity.
Volume: 166
Issue: 2
Pages: 230-5
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Publication
21299233 | J:170921
First Author: Tinoco AD
Year: 2011
Journal: Biochemistry
Title: A peptidomics strategy to elucidate the proteolytic pathways that inactivate peptide hormones.
Volume: 50
Issue: 12
Pages: 2213-22
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Publication
22101691 | J:180368
First Author: Yan S
Year: 2012
Journal: Eur J Immunol
Title: Enhanced ovalbumin-induced airway inflammation in CD26-/- mice.
Volume: 42
Issue: 2
Pages: 533-40
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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