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Search results 1 to 8 out of 8 for Drc2

0.01s

Type

Details

Score

Protein

Q8VHI7

Organism:	Mus musculus/domesticus
Length:	493
Fragment?:	false

•

Protein

Q8VHI7-2

Organism:	Mus musculus/domesticus
Length:	104
Fragment?:	false

•

Protein

Q3UXA4

Organism:	Mus musculus/domesticus
Length:	171
Fragment?:	false

•

Protein Domain

IPR039750 | DRC1/DRC2

Type:

Family

Description:

DRC1 is a key component of the nexin-dynein regulatory complex (N-DRC), essential for N-DRC integrity. It is required for the assembly and regulation of specific classes of inner dynein arm motors. It may also function to restrict dynein-driven microtubule sliding, thus aiding in the generation of ciliary bending []. Mutations of DRC1 gene cause Ciliary dyskinesia, primary, 21 (CILD21), which is a disorder characterised by abnormalities of motile cilia []. DRC2, also known as CCDC65, is an essential component of the nexin-dynein regulatory complex (N-DRC)[]. DRC2 is necessary for the co-assembly of DRC2 and DRC1 to form the base plate of N-DRC.

•

Protein

A0A2R8W6P2

Organism:	Mus musculus/domesticus
Length:	104
Fragment?:	false

•

Publication

23354437 | -

First Author:	Wirschell M
Year:	2013
Journal:	Nat Genet
Title:	The nexin-dynein regulatory complex subunit DRC1 is essential for motile cilia function in algae and humans.
Volume:	45
Issue:	3
Pages:	262-8

•

Protein

Q3USS3

Organism:	Mus musculus/domesticus
Length:	753
Fragment?:	false

•

Publication

24094744 | -

First Author:	Austin-Tse C
Year:	2013
Journal:	Am J Hum Genet
Title:	Zebrafish Ciliopathy Screen Plus Human Mutational Analysis Identifies C21orf59 and CCDC65 Defects as Causing Primary Ciliary Dyskinesia.
Volume:	93
Issue:	4
Pages:	672-86

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Search results 1 to 8 out of 8 for Drc2

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