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Search results 1 to 100 out of 144 for Elovl1

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0.054s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Protein Domain
Type: Family
Description: Elongation of very long chain fatty acids protein 1 (ELOVL1) is a component of the the long-chain fatty acids elongation cycle. It is a transmembrane enzyme in the endoplasmic reticulum that adds two carbons per cycle to long- and very long-chain fatty acids with a preference for condensing saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA [].
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Ohno Y
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: ELOVL1 production of C24 acyl-CoAs is linked to C24 sphingolipid synthesis.
Volume: 107
Issue: 43
Pages: 18439-44
Protein
Organism: Mus musculus
Length: 279  
Fragment?: false
Protein
Organism: Mus musculus
Length: 279  
Fragment?: false
Publication
First Author: Asadi A
Year: 2002
Journal: J Biol Chem
Title: Elovl1 and p55Cdc genes are localized in a tail-to-tail array and are co-expressed in proliferating cells.
Volume: 277
Issue: 21
Pages: 18494-500
Publication
First Author: Sassa T
Year: 2018
Journal: FASEB J
Title: Very long-chain tear film lipids produced by fatty acid elongase ELOVL1 prevent dry eye disease in mice.
Volume: 32
Issue: 6
Pages: 2966-2978
MGI Directed Relationship Property
Name: Non-mouse_Gene_Symbol
Value: ELOVL1
Publication
First Author: Edagawa M
Year: 2018
Journal: Biochim Biophys Acta Mol Cell Biol Lipids
Title: Widespread tissue distribution and synthetic pathway of polyunsaturated C24:2 sphingolipids in mammals.
Volume: 1863
Issue: 12
Pages: 1441-1448
Publication
First Author: Sassa T
Year: 2012
Journal: Biochim Biophys Acta
Title: A shift in sphingolipid composition from C24 to C16 increases susceptibility to apoptosis in HeLa cells.
Volume: 1821
Issue: 7
Pages: 1031-7
Publication
First Author: Guttenplan KA
Year: 2021
Journal: Nature
Title: Neurotoxic reactive astrocytes induce cell death via saturated lipids.
Volume: 599
Issue: 7883
Pages: 102-107
Publication
First Author: Tvrdik P
Year: 2000
Journal: J Cell Biol
Title: Role of a new mammalian gene family in the biosynthesis of very long chain fatty acids and sphingolipids.
Volume: 149
Issue: 3
Pages: 707-18
Publication
First Author: Tanno H
Year: 2021
Journal: Biochim Biophys Acta Mol Cell Biol Lipids
Title: Production of branched-chain very-long-chain fatty acids by fatty acid elongases and their tissue distribution in mammals.
Volume: 1866
Issue: 1
Pages: 158842
Publication
First Author: Sassa T
Year: 2013
Journal: Mol Cell Biol
Title: Impaired epidermal permeability barrier in mice lacking elovl1, the gene responsible for very-long-chain fatty acid production.
Volume: 33
Issue: 14
Pages: 2787-96
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: LORCH J
Year: 1947
Journal: Q J Microsc Sci
Title: Note on the cytological localization of alkaline phosphatase.
Volume: 88
Issue: Pt 2
Pages: 159-61
GXD Expression      
Probe: MGI:6781805
Assay Type: RT-PCR
Annotation Date: 2021-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:6781897
Age: postnatal adult
Specimen Label: Spleen
Detected: true
Specimen Num: 12
GXD Expression      
Probe: MGI:6781805
Assay Type: RT-PCR
Annotation Date: 2021-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:6781897
Age: postnatal adult
Specimen Label: Kidney
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:6423349
Assay Type: RT-PCR
Annotation Date: 2020-05-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752826
Stage: TS26
Assay Id: MGI:6423362
Age: embryonic day 18.5
Specimen Label: WT
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:6423349
Assay Type: RT-PCR
Annotation Date: 2020-05-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752826
Stage: TS26
Assay Id: MGI:6423362
Age: embryonic day 18.5
Specimen Label: KO
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:6781805
Assay Type: RT-PCR
Annotation Date: 2021-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:6781897
Age: postnatal adult
Specimen Label: Lung
Detected: true
Specimen Num: 10
GXD Expression      
Probe: MGI:6781805
Assay Type: RT-PCR
Annotation Date: 2021-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:6781897
Age: postnatal adult
Specimen Label: Sk.Mus
Detected: true
Specimen Num: 11
GXD Expression      
Probe: MGI:6781805
Assay Type: RT-PCR
Annotation Date: 2021-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:6781897
Age: postnatal adult
Specimen Label: Heart
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:6781805
Assay Type: RT-PCR
Annotation Date: 2021-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603910
Stage: TS10
Assay Id: MGI:6781897
Age: embryonic day 7.0
Specimen Label: 7 dpc
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:6781805
Assay Type: RT-PCR
Annotation Date: 2021-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603918
Stage: TS18
Assay Id: MGI:6781897
Age: embryonic day 11.0
Specimen Label: 11 dpc
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:6781805
Assay Type: RT-PCR
Annotation Date: 2021-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:6781897
Age: embryonic day 15.0
Specimen Label: 15 dpc
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:6781805
Assay Type: RT-PCR
Annotation Date: 2021-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603925
Stage: TS25
Assay Id: MGI:6781897
Age: embryonic day 17.0
Specimen Label: 17 dpc
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:6781805
Assay Type: RT-PCR
Annotation Date: 2021-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1894821
Stage: TS21
Assay Id: MGI:6781897
Age: embryonic day 13.5
Specimen Label: WT 13.5
Detected: true
Specimen Num: 16
GXD Expression      
Probe: MGI:6781805
Assay Type: RT-PCR
Annotation Date: 2021-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1894822
Stage: TS22
Assay Id: MGI:6781897
Age: embryonic day 14.5
Specimen Label: WT 14.5
Detected: true
Specimen Num: 17
GXD Expression      
Probe: MGI:6781805
Assay Type: RT-PCR
Annotation Date: 2021-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1894823
Stage: TS23
Assay Id: MGI:6781897
Age: embryonic day 15.5
Specimen Label: WT 15.5
Detected: true
Specimen Num: 18
GXD Expression      
Probe: MGI:6781805
Assay Type: RT-PCR
Annotation Date: 2021-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6781897
Age: postnatal adult
Specimen Label: Liver
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:6781805
Assay Type: RT-PCR
Annotation Date: 2021-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1736321
Stage: TS21
Assay Id: MGI:6781897
Age: embryonic day 13.5
Specimen Label: WT MEE 13.5
Detected: true
Specimen Num: 19
GXD Expression      
Probe: MGI:6781805
Assay Type: RT-PCR
Annotation Date: 2021-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1736322
Stage: TS22
Assay Id: MGI:6781897
Age: embryonic day 14.5
Specimen Label: WT MEE 14.5
Detected: true
Specimen Num: 20
GXD Expression      
Probe: MGI:6781805
Assay Type: RT-PCR
Annotation Date: 2021-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1736321
Stage: TS21
Assay Id: MGI:6781897
Age: embryonic day 13.5
Specimen Label: Mutant 13.5
Detected: true
Specimen Num: 21
GXD Expression      
Probe: MGI:6781805
Assay Type: RT-PCR
Annotation Date: 2021-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1736322
Stage: TS22
Assay Id: MGI:6781897
Age: embryonic day 14.5
Specimen Label: Mutant 14.5
Detected: true
Specimen Num: 22
GXD Expression      
Probe: MGI:6781805
Assay Type: RT-PCR
Annotation Date: 2021-10-26
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:6781897
Age: postnatal adult
Specimen Label: Testis
Detected: true
Specimen Num: 13
GXD Expression      
Probe: MGI:6781805
Assay Type: RT-PCR
Annotation Date: 2021-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1736220
Stage: TS20
Assay Id: MGI:6781897
Age: embryonic day 12.5
Specimen Label: WT 12.5
Detected: true
Specimen Num: 15
GXD Expression      
Probe: MGI:5824359
Assay Type: RT-PCR
Annotation Date: 2017-02-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752526
Stage: TS26
Assay Id: MGI:5824387
Age: embryonic day 18.5
Specimen Label: +/+
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5824359
Assay Type: RT-PCR
Annotation Date: 2017-02-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1752526
Stage: TS26
Assay Id: MGI:5824387
Age: embryonic day 18.5
Specimen Label: -/-
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:5824359
Assay Type: RT-PCR
Annotation Date: 2017-02-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752526
Stage: TS26
Assay Id: MGI:5824504
Age: embryonic day 18.5
Specimen Label: +/+
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5824359
Assay Type: RT-PCR
Annotation Date: 2017-02-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1752526
Stage: TS26
Assay Id: MGI:5824504
Age: embryonic day 18.5
Specimen Label: -/-
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:6781805
Assay Type: RT-PCR
Annotation Date: 2021-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752528
Stage: TS28
Assay Id: MGI:6781897
Age: postnatal adult
Specimen Label: Skin
Detected: true
Specimen Num: 14
GXD Expression      
Probe: MGI:4437746
Assay Type: RT-PCR
Annotation Date: 2010-03-23
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:4437808
Age: postnatal adult
Specimen Label: wild-type
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:4437746
Assay Type: RT-PCR
Annotation Date: 2010-03-23
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:4437808
Age: postnatal adult
Specimen Label: Szt2m1Frk
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:6781805
Assay Type: RT-PCR
Annotation Date: 2021-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6781897
Age: postnatal adult
Specimen Label: Brain
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:5824379
Assay Type: RNA in situ
Annotation Date: 2017-02-17
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3278626
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:5824530
Age: embryonic day 18.5
Specimen Label: S4 +/+
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5824379
Assay Type: RNA in situ
Annotation Date: 2017-02-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3278626
Stage: TS26
Assay Id: MGI:5824530
Age: embryonic day 18.5
Specimen Label: S4 -/-
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:5824379
Assay Type: RNA in situ
Annotation Date: 2017-02-17
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3278526
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:5824530
Age: embryonic day 18.5
Specimen Label: S4 +/+
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5824379
Assay Type: RNA in situ
Annotation Date: 2017-02-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3278526
Stage: TS26
Assay Id: MGI:5824530
Age: embryonic day 18.5
Specimen Label: S4 -/-
Detected: false
Specimen Num: 2
Publication
First Author: Honda Y
Year: 2018
Journal: J Invest Dermatol
Title: Decreased Skin Barrier Lipid Acylceramide and Differentiation-Dependent Gene Expression in Ichthyosis Gene Nipal4-Knockout Mice.
Volume: 138
Issue: 4
Pages: 741-749
Publication
First Author: Frankel WN
Year: 2009
Journal: Genes Brain Behav
Title: Szt2, a novel gene for seizure threshold in mice.
Volume: 8
Issue: 5
Pages: 568-76
Publication
First Author: Rorick NK
Year: 2011
Journal: Am J Med Genet A
Title: Genomic strategy identifies a missense mutation in WD-repeat domain 65 (WDR65) in an individual with Van der Woude syndrome.
Volume: 155A
Issue: 6
Pages: 1314-21
Publication
First Author: Miyamoto M
Year: 2020
Journal: J Invest Dermatol
Title: Severe Skin Permeability Barrier Dysfunction in Knockout Mice Deficient in a Fatty Acid ω-Hydroxylase Crucial to Acylceramide Production.
Volume: 140
Issue: 2
Pages: 319-326.e4
Publication
First Author: Yu Z
Year: 2006
Journal: Dev Biol
Title: The Grainyhead-like epithelial transactivator Get-1/Grhl3 regulates epidermal terminal differentiation and interacts functionally with LMO4.
Volume: 299
Issue: 1
Pages: 122-36
Publication
First Author: Pichery M
Year: 2017
Journal: Hum Mol Genet
Title: PNPLA1 defects in patients with autosomal recessive congenital ichthyosis and KO mice sustain PNPLA1 irreplaceable function in epidermal omega-O-acylceramide synthesis and skin permeability barrier.
Volume: 26
Issue: 10
Pages: 1787-1800
Publication
First Author: Duteil D
Year: 2016
Journal: Cell Rep
Title: Lsd1 Ablation Triggers Metabolic Reprogramming of Brown Adipose Tissue.
Volume: 17
Issue: 4
Pages: 1008-1021
Publication
First Author: Lau CG
Year: 2014
Journal: Mol Reprod Dev
Title: Morphology-based mammalian stem cell tests reveal potential developmental toxicity of donepezil.
Volume: 81
Issue: 11
Pages: 994-1008
Publication      
First Author: Taconic
Year: 2006
Journal: MGI Direct Data Submission
Title: Information obtained from Taconic website.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication      
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference