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Search results 1 to 100 out of 106 for Elp5

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0.047s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Domain
Type: Family
Description: Elongator is a 6 subunit protein complex highly conserved in eukaryotes. The human Elongator six-subunit complex, known as holo-Elongator, has histone acetyltransferase activity directed against histone H3 and H4 [, ]. It consists of two subcomplexes, a core subcomplex (ELP1-3), and an accessory subcomplex (ELP4-6) []. The elongator complex has been associated with many cellular activities, including transcriptional elongation [, ], but its main function is tRNA modification [, ]. It is required for the formation of 5-methoxy-carbonylmethyl (mcm5) and 5-carbamoylmethyl (ncm5) groups on uridine nucleosides present at the wobble position of many tRNAs [].This entry represents Elongator complex protein 5 (ELP5).
Protein
Organism: Mus musculus/domesticus
Length: 300  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 115  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 140  
Fragment?: true
Publication
First Author: Otero G
Year: 1999
Journal: Mol Cell
Title: Elongator, a multisubunit component of a novel RNA polymerase II holoenzyme for transcriptional elongation.
Volume: 3
Issue: 1
Pages: 109-18
Publication
First Author: Krogan NJ
Year: 2001
Journal: Mol Cell Biol
Title: Characterization of a six-subunit holo-elongator complex required for the regulated expression of a group of genes in Saccharomyces cerevisiae.
Volume: 21
Issue: 23
Pages: 8203-12
Publication
First Author: Huang B
Year: 2005
Journal: RNA
Title: An early step in wobble uridine tRNA modification requires the Elongator complex.
Volume: 11
Issue: 4
Pages: 424-36
Publication
First Author: Glatt S
Year: 2012
Journal: Transcription
Title: Elongator: transcriptional or translational regulator?
Volume: 3
Issue: 6
Pages: 273-6
Publication
First Author: Bauer F
Year: 2012
Journal: Cell Cycle
Title: A coordinated codon-dependent regulation of translation by Elongator.
Volume: 11
Issue: 24
Pages: 4524-9
Publication
First Author: Winkler GS
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Elongator is a histone H3 and H4 acetyltransferase important for normal histone acetylation levels in vivo.
Volume: 99
Issue: 6
Pages: 3517-22
Publication
First Author: Hawkes NA
Year: 2002
Journal: J Biol Chem
Title: Purification and characterization of the human elongator complex.
Volume: 277
Issue: 4
Pages: 3047-52
Publication
First Author: Lin Z
Year: 2012
Journal: J Biol Chem
Title: Crystal structure of elongator subcomplex Elp4-6.
Volume: 287
Issue: 25
Pages: 21501-8
Publication
First Author: Close P
Year: 2012
Journal: J Biol Chem
Title: DERP6 (ELP5) and C3ORF75 (ELP6) regulate tumorigenicity and migration of melanoma cells as subunits of Elongator.
Volume: 287
Issue: 39
Pages: 32535-45
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression      
Probe: MGI:5634917
Assay Type: Western blot
Annotation Date: 2015-05-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754424
Stage: TS24
Assay Id: MGI:5635063
Age: embryonic day 16.0
Specimen Label: Cortex
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5634917
Assay Type: Western blot
Annotation Date: 2015-05-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3266524
Stage: TS24
Assay Id: MGI:5635063
Age: embryonic day 16.0
Specimen Label: GE
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5001592
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2769723
Stage: TS23
Assay Id: MGI:5542146
Age: embryonic day 15.5
Image: GUDMAP:11144
Specimen Label: GUDMAP:11144
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5001592
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2769723
Stage: TS23
Assay Id: MGI:5542146
Age: embryonic day 15.5
Image: GUDMAP:11145
Specimen Label: GUDMAP:11145
Detected: false
Specimen Num: 2
GXD Expression  
Probe: MGI:5634917
Assay Type: Immunohistochemistry
Annotation Date: 2015-05-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Widespread
Stage: TS22
Assay Id: MGI:5635103
Age: embryonic day 14.5
Note: Expressed in all cells.
Specimen Label: 1V
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5634917
Assay Type: Immunohistochemistry
Annotation Date: 2015-05-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Widespread
Stage: TS22
Assay Id: MGI:5635103
Age: embryonic day 14.5
Specimen Label: 1W
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:5001592
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2853323
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5542146
Age: embryonic day 15.5
Image: GUDMAP:11144
Specimen Label: GUDMAP:11144
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5634917
Assay Type: Immunohistochemistry
Annotation Date: 2015-05-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271222
Pattern: Widespread
Stage: TS22
Assay Id: MGI:5635103
Age: embryonic day 14.5
Note: Expressed in all cells.
Specimen Label: 1V
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5634917
Assay Type: Immunohistochemistry
Annotation Date: 2015-05-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271222
Pattern: Widespread
Stage: TS22
Assay Id: MGI:5635103
Age: embryonic day 14.5
Specimen Label: 1W
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:5001592
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2845723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5542146
Age: embryonic day 15.5
Image: GUDMAP:11144
Specimen Label: GUDMAP:11144
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5001592
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2845723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5542146
Age: embryonic day 15.5
Image: GUDMAP:11145
Specimen Label: GUDMAP:11145
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5001592
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:1795023
Stage: TS23
Assay Id: MGI:5542146
Age: embryonic day 15.5
Image: GUDMAP:11144
Specimen Label: GUDMAP:11144
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5001592
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:1795023
Stage: TS23
Assay Id: MGI:5542146
Age: embryonic day 15.5
Image: GUDMAP:11145
Specimen Label: GUDMAP:11145
Detected: false
Specimen Num: 2
GXD Expression  
Probe: MGI:5634917
Assay Type: Immunohistochemistry
Annotation Date: 2015-05-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:5635103
Age: embryonic day 14.5
Note: Expressed in the cytoplasm.
Specimen Label: 1X/X'
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:5001592
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:1869223
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5542146
Age: embryonic day 15.5
Image: GUDMAP:11144
Specimen Label: GUDMAP:11144
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5001592
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2854023
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5542146
Age: embryonic day 15.5
Image: GUDMAP:11145
Specimen Label: GUDMAP:11145
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5001592
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2762123
Stage: TS23
Assay Id: MGI:5542146
Age: embryonic day 15.5
Image: GUDMAP:11144
Specimen Label: GUDMAP:11144
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5001592
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2762123
Stage: TS23
Assay Id: MGI:5542146
Age: embryonic day 15.5
Image: GUDMAP:11145
Specimen Label: GUDMAP:11145
Detected: false
Specimen Num: 2
GXD Expression  
Probe: MGI:5001592
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:1797223
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5542146
Age: embryonic day 15.5
Image: GUDMAP:11144
Specimen Label: GUDMAP:11144
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5001592
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:1832123
Stage: TS23
Assay Id: MGI:5542146
Age: embryonic day 15.5
Image: GUDMAP:11144
Specimen Label: GUDMAP:11144
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5001592
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:1832123
Stage: TS23
Assay Id: MGI:5542146
Age: embryonic day 15.5
Image: GUDMAP:11145
Specimen Label: GUDMAP:11145
Detected: false
Specimen Num: 2
GXD Expression  
Probe: MGI:5001592
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2851823
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5542146
Age: embryonic day 15.5
Image: GUDMAP:11144
Specimen Label: GUDMAP:11144
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5001592
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2851823
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5542146
Age: embryonic day 15.5
Image: GUDMAP:11145
Specimen Label: GUDMAP:11145
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5001592
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2760523
Stage: TS23
Assay Id: MGI:5542146
Age: embryonic day 15.5
Image: GUDMAP:11144
Specimen Label: GUDMAP:11144
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5001592
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2760523
Stage: TS23
Assay Id: MGI:5542146
Age: embryonic day 15.5
Image: GUDMAP:11145
Specimen Label: GUDMAP:11145
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:5001592
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2852723
Stage: TS23
Assay Id: MGI:5542146
Age: embryonic day 15.5
Image: GUDMAP:11144
Specimen Label: GUDMAP:11144
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5001592
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2852723
Stage: TS23
Assay Id: MGI:5542146
Age: embryonic day 15.5
Image: GUDMAP:11145
Specimen Label: GUDMAP:11145
Detected: false
Specimen Num: 2
GXD Expression  
Probe: MGI:5001592
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2874723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5542146
Age: embryonic day 15.5
Image: GUDMAP:11145
Specimen Label: GUDMAP:11145
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5001592
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2850023
Stage: TS23
Assay Id: MGI:5542146
Age: embryonic day 15.5
Image: GUDMAP:11144
Specimen Label: GUDMAP:11144
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5001592
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2850023
Stage: TS23
Assay Id: MGI:5542146
Age: embryonic day 15.5
Image: GUDMAP:11145
Specimen Label: GUDMAP:11145
Detected: false
Specimen Num: 2
GXD Expression  
Probe: MGI:5001592
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:1796223
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5542146
Age: embryonic day 15.5
Image: GUDMAP:11145
Specimen Label: GUDMAP:11145
Detected: true
Specimen Num: 2
Publication
First Author: Spanjaard RA
Year: 1997
Journal: Cancer Res
Title: Clone 10d/BM28 (CDCL1), an early S-phase protein, is an important growth regulator of melanoma.
Volume: 57
Issue: 22
Pages: 5122-8
Publication
First Author: Creppe C
Year: 2009
Journal: Cell
Title: Elongator controls the migration and differentiation of cortical neurons through acetylation of alpha-tubulin.
Volume: 136
Issue: 3
Pages: 551-64
Publication
First Author: Freeman S
Year: 2019
Journal: EMBO Rep
Title: Proteostasis is essential during cochlear development for neuron survival and hair cell polarity.
Volume: 20
Issue: 9
Pages: e47097
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication      
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication        
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database