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Search results 1 to 100 out of 105 for Emc6

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Hits by Pathway

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Hits by Strain

Type Details Score
Gene
83460 | EMC6
Type: gene
Organism: human
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Gene
448052 | emc6
Type: gene
Organism: frog, western clawed
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Gene
287477 | Emc6
Type: gene
Organism: rat
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Gene
454433 | EMC6
Type: gene
Organism: chimpanzee
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Gene
613551 | EMC6
Type: gene
Organism: cattle
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Gene
100856142 | EMC6
Type: gene
Organism: dog, domestic
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Gene
417604 | EMC6
Type: gene
Organism: chicken
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Gene
337220 | emc6
Type: gene
Organism: zebrafish
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Gene
707030 | EMC6
Type: gene
Organism: macaque, rhesus
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Protein Domain
IPR008504 | Emc6
Type: Family
Description: This entry represents ER membrane protein complex subunit 6 (Emc6). Emc6 is a component of the ER membrane protein complex (EMC), which is composed of Emc1, Emc2, Emc3, Emc4, Emc5 and Emc6 in budding yeast []. The EMC complex is required for efficient folding of proteins in the ER [, ].
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Protein Coding Gene
MGI:1913298 | Emc6
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q9CQW0
Organism: Mus musculus/domesticus
Length: 110  
Fragment?: false
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Publication
23431131 | -
First Author: Richard M
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Biosynthesis of ionotropic acetylcholine receptors requires the evolutionarily conserved ER membrane complex.
Volume: 110
Issue: 11
Pages: E1055-63
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Publication
19325107 | -
First Author: Jonikas MC
Year: 2009
Journal: Science
Title: Comprehensive characterization of genes required for protein folding in the endoplasmic reticulum.
Volume: 323
Issue: 5922
Pages: 1693-7
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Protein Coding Gene
MGP_CAROLIEiJ_G0016688 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0018654 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0018622 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0018591 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0018594 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0018407 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1913298 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0019045 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0017962 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0018379 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0018488 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0018479 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0018559 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0018502 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0019087 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0017735 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0018016 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0017821 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0017525 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1619828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691642
Age: postnatal adult
Image: TCP_2460702
Specimen Label: TCP_2460702
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1619828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691642
Age: postnatal adult
Image: TCP_2460689
Specimen Label: TCP_2460689
Detected: true
Specimen Num: 18
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3267828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691642
Age: postnatal adult
Image: TCP_2460699
Specimen Label: TCP_2460699
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3267828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691642
Age: postnatal adult
Image: TCP_2460686
Specimen Label: TCP_2460686
Detected: true
Specimen Num: 15
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1778728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691642
Age: postnatal adult
Image: TCP_2460701
Specimen Label: TCP_2460701
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1778728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691642
Age: postnatal adult
Image: TCP_2460688
Specimen Label: TCP_2460688
Detected: true
Specimen Num: 17
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1672828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691642
Age: postnatal adult
Image: TCP_2460692
Specimen Label: TCP_2460692
Detected: true
Specimen Num: 21
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3278228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691642
Age: postnatal adult
Image: TCP_2460697
Specimen Label: TCP_2460697
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1610528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691642
Age: postnatal adult
Image: TCP_2460703
Specimen Label: TCP_2460703
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1610528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691642
Age: postnatal adult
Image: TCP_2460690
Specimen Label: TCP_2460690
Detected: true
Specimen Num: 19
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1920928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691642
Age: postnatal adult
Image: TCP_2460700
Specimen Label: TCP_2460700
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1920928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691642
Age: postnatal adult
Image: TCP_2460687
Specimen Label: TCP_2460687
Detected: true
Specimen Num: 16
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1684628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691642
Age: postnatal adult
Image: TCP_2460704
Specimen Label: TCP_2460704
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1684628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691642
Age: postnatal adult
Image: TCP_2460691
Specimen Label: TCP_2460691
Detected: true
Specimen Num: 20
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1750328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691642
Age: postnatal adult
Image: TCP_2460693
Specimen Label: TCP_2460693
Detected: true
Specimen Num: 22
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1832128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691642
Age: postnatal adult
Image: TCP_2460696
Specimen Label: TCP_2460696
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1832128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691642
Age: postnatal adult
Image: TCP_2460683
Specimen Label: TCP_2460683
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1752528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691642
Age: postnatal adult
Image: TCP_2460706
Specimen Label: TCP_2460706
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1752528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691642
Age: postnatal adult
Image: TCP_2460694
Specimen Label: TCP_2460694
Detected: true
Specimen Num: 23
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1757728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691642
Age: postnatal adult
Image: TCP_2460707
Specimen Label: TCP_2460707
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1757728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691642
Age: postnatal adult
Image: TCP_2460695
Specimen Label: TCP_2460695
Detected: true
Specimen Num: 24
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691642
Age: postnatal adult
Image: TCP_2460698
Specimen Label: TCP_2460698
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691642
Age: postnatal adult
Image: TCP_2460684
Specimen Label: TCP_2460684
Detected: true
Specimen Num: 13
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691642
Age: postnatal adult
Image: TCP_2460685
Specimen Label: TCP_2460685
Detected: true
Specimen Num: 14
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Publication
- | J:74842
   
First Author: Strausberg R
Year: 2002
Journal: GenBank Submission
Title: Mus musculus, RIKEN cDNA 0610009E20 gene, clone MGC: 35775 IMAGE: 5101119, mRNA, complete cds
Pages: BC022104
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Publication
29242231 | J:320079
First Author: Guna A
Year: 2018
Journal: Science
Title: The ER membrane protein complex is a transmembrane domain insertase.
Volume: 359
Issue: 6374
Pages: 470-473
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Publication
- | J:342607
       
First Author: Birgit Meldal and Sandra Orchard (1). (1) European Bioinformatics Institute (EBI), Hinxton, Cambridgeshire, United Kingdom
Year: 2023
Title: Manual transfer of experimentally-verified manual GO annotation data to homologous complexes by curator judgment of sequence, composition and function similarity
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Publication
24194600 | J:228563
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
33177505 | J:331593
First Author: Tan JH
Year: 2020
Journal: Cell Death Dis
Title: EMC6 regulates acinar apoptosis via APAF1 in acute and chronic pancreatitis.
Volume: 11
Issue: 11
Pages: 966
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Publication
10818110 | -
First Author: Hoffenberg S
Year: 2000
Journal: J Biol Chem
Title: A novel membrane-anchored Rab5 interacting protein required for homotypic endosome fusion.
Volume: 275
Issue: 32
Pages: 24661-9
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Publication
23182941 | -
First Author: Li Y
Year: 2013
Journal: Autophagy
Title: A novel ER-localized transmembrane protein, EMC6, interacts with RAB5A and regulates cell autophagy.
Volume: 9
Issue: 2
Pages: 150-63
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Protein Domain
IPR029008 | EMC6-like
Type: Family
Description: This family consists of several Rab5-interacting proteins (RIP5 or Rab5ip) including ER membrane protein complex subunit 6 (EMC6) and RCAF1. The ras-related GTPase rab5 is rate-limiting for homotypic early endosome fusion. Rab5ip represents a novel rab5 interacting protein that may function on endocytic vesicles as a receptor for rab5-GDP and participate in the activation of rab5 []. EMC6 interacts with Rab5A and BECN1/Beclin 1 and regulates autophagosome formation []. EMC6 is part of the EMC complex, required for efficient folding of proteins in the ER []and for post-translational membrane insertion of tail-anchored (TA) proteins [, ]. RCAF1 acts as an assembly factor for mitochondrial respiratory complexes [].
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