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Search results 1 to 100 out of 393 for Enpp1

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Hits by Strain

Type Details Score
Gene
5167 | ENPP1
Type: gene
Organism: human
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Gene
100422807 | enpp1
Type: gene
Organism: frog, western clawed
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Gene
85496 | Enpp1
Type: gene
Organism: rat
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Gene
463002 | ENPP1
Type: gene
Organism: chimpanzee
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Gene
615535 | ENPP1
Type: gene
Organism: cattle
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Gene
100856150 | ENPP1
Type: gene
Organism: dog, domestic
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Gene
426929 | ENPP1
Type: gene
Organism: chicken
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Gene
562399 | enpp1
Type: gene
Organism: zebrafish
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Gene
710140 | ENPP1
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:97370 | Enpp1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
17849011 | J:133011
First Author: Liang J
Year: 2007
Journal: PLoS One
Title: Role of ENPP1 on adipocyte maturation.
Volume: 2
Issue: 9
Pages: e882
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Publication
27406238 | J:249052
First Author: Palazzo L
Year: 2016
Journal: FEBS J
Title: ENPP1 processes protein ADP-ribosylation in vitro.
Volume: 283
Issue: 18
Pages: 3371-88
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Publication
29244957 | J:281390
First Author: Thumbigere-Math V
Year: 2018
Journal: J Dent Res
Title: Hypercementosis Associated with ENPP1 Mutations and GACI.
Volume: 97
Issue: 4
Pages: 432-441
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Publication
25344812 | J:273512
First Author: Li L
Year: 2014
Journal: Nat Chem Biol
Title: Hydrolysis of 2'3'-cGAMP by ENPP1 and design of nonhydrolyzable analogs.
Volume: 10
Issue: 12
Pages: 1043-8
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Publication
29533727 | J:289166
First Author: Wolf M
Year: 2018
Journal: J Dent Res
Title: Reduced Orthodontic Tooth Movement in Enpp1 Mutant Mice with Hypercementosis.
Volume: 97
Issue: 8
Pages: 937-945
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Publication
38117852 | J:352677
First Author: Wang S
Year: 2023
Journal: Proc Natl Acad Sci U S A
Title: ENPP1 is an innate immune checkpoint of the anticancer cGAMP-STING pathway in breast cancer.
Volume: 120
Issue: 52
Pages: e2313693120
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Publication
29259245 | J:287506
First Author: Wang H
Year: 2017
Journal: Sci Rep
Title: ATP-degrading ENPP1 is required for survival (or persistence) of long-lived plasma cells.
Volume: 7
Issue: 1
Pages: 17867
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Publication
24770645 | J:250073
First Author: Takabayashi S
Year: 2014
Journal: Exp Anim
Title: A new Enpp1 allele, Enpp1(ttw-Ham), identified in an ICR closed colony.
Volume: 63
Issue: 2
Pages: 193-204
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Publication
28798354 | J:273749
First Author: Watanabe R
Year: 2017
Journal: Sci Rep
Title: Enpp1 is an anti-aging factor that regulates Klotho under phosphate overload conditions.
Volume: 7
Issue: 1
Pages: 7786
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Publication
39622844 | J:381349
First Author: Baird JR
Year: 2024
Journal: Sci Rep
Title: A novel small molecule Enpp1 inhibitor improves tumor control following radiation therapy by targeting stromal Enpp1 expression.
Volume: 14
Issue: 1
Pages: 29913
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Publication
42302792 | J:389437
First Author: Su L
Year: 2026
Journal: Cell Stem Cell
Title: ENPP1 blockade with a humanized monoclonal antibody enhances renal repair after acute kidney injury.
Volume: 33
Issue: 7
Pages: 1110-1126.e7
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Publication
40914167 | J:382876
First Author: Wang S
Year: 2025
Journal: Cell Rep Med
Title: ENPP1 inhibitor with ultralong drug-target residence time as an innate immune checkpoint blockade cancer therapy.
Volume: 6
Issue: 9
Pages: 102336
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Publication
30111653 | J:266558
 
First Author: Jin Y
Year: 2018
Journal: Development
Title: Enpp1 inhibits ectopic joint calcification and maintains articular chondrocytes by repressing hedgehog signaling.
Volume: 145
Issue: 18
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Publication
19419305 | J:168664
First Author: Babij P
Year: 2009
Journal: J Bone Miner Res
Title: New variants in the Enpp1 and Ptpn6 genes cause low BMD, crystal-related arthropathy, and vascular calcification.
Volume: 24
Issue: 9
Pages: 1552-64
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Publication
24530784 | J:267161
First Author: Serrano RL
Year: 2014
Journal: Atherosclerosis
Title: Mono-allelic and bi-allelic ENPP1 deficiency promote post-injury neointimal hyperplasia associated with increased C/EBP homologous protein expression.
Volume: 233
Issue: 2
Pages: 493-502
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Publication
32980560 | J:301195
 
First Author: Maulding ND
Year: 2021
Journal: Bone
Title: Genetic pathways disrupted by ENPP1 deficiency provide insight into mechanisms of osteoporosis, osteomalacia, and paradoxical mineralization.
Volume: 142
Pages: 115656
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Publication
30158213 | J:266200
 
First Author: Khan T
Year: 2018
Journal: Dis Model Mech
Title: ENPP1 enzyme replacement therapy improves blood pressure and cardiovascular function in a mouse model of generalized arterial calcification of infancy.
Volume: 11
Issue: 10
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Publication
25479107 | J:215824
First Author: Li Q
Year: 2014
Journal: PLoS One
Title: Spontaneous asj-2J mutant mouse as a model for generalized arterial calcification of infancy: a large deletion/insertion mutation in the Enpp1 gene.
Volume: 9
Issue: 12
Pages: e113542
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Publication
- | J:174912
     
First Author: Harris BS
Year: 2011
Journal: MGI Direct Data Submission
Title: Ages with stiffened joints, A new mutation in Enpp1
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Publication
35588451 | J:352678
First Author: Carozza JA
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: ENPP1's regulation of extracellular cGAMP is a ubiquitous mechanism of attenuating STING signaling.
Volume: 119
Issue: 21
Pages: e2119189119
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Publication
30356045 | J:273505
First Author: Kato K
Year: 2018
Journal: Nat Commun
Title: Structural insights into cGAMP degradation by Ecto-nucleotide pyrophosphatase phosphodiesterase 1.
Volume: 9
Issue: 1
Pages: 4424
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Publication
23027977 | J:190295
First Author: Kato K
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Crystal structure of Enpp1, an extracellular glycoprotein involved in bone mineralization and insulin signaling.
Volume: 109
Issue: 42
Pages: 16876-81
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Publication
38042486 | J:351170
First Author: Arima T
Year: 2024
Journal: J Biol Chem
Title: Cartilage tissues regulate systemic aging via ectonucleotide pyrophosphatase/phosphodiesterase 1 in mice.
Volume: 300
Issue: 1
Pages: 105512
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Publication
23798568 | J:201689
First Author: Li Q
Year: 2013
Journal: Dis Model Mech
Title: Mutant Enpp1asj mice as a model for generalized arterial calcification of infancy.
Volume: 6
Issue: 5
Pages: 1227-35
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Publication
36477209 | J:334715
First Author: Choi H
Year: 2022
Journal: Sci Rep
Title: Npp1 prevents external tooth root resorption by regulation of cervical cementum integrity.
Volume: 12
Issue: 1
Pages: 21158
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Publication
26763447 | J:229906
First Author: Li Q
Year: 2016
Journal: J Invest Dermatol
Title: Dual Effects of Bisphosphonates on Ectopic Skin and Vascular Soft Tissue Mineralization versus Bone Microarchitecture in a Mouse Model of Generalized Arterial Calcification of Infancy.
Volume: 136
Issue: 1
Pages: 275-283
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Publication
28402956 | J:251784
First Author: Kingman J
Year: 2017
Journal: Oncotarget
Title: Elevated dietary magnesium during pregnancy and postnatal life prevents ectopic mineralization in Enpp1asj mice, a model for generalized arterial calcification of infancy.
Volume: 8
Issue: 24
Pages: 38152-38160
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Publication
27863377 | J:319353
First Author: Siu SY
Year: 2016
Journal: Oncotarget
Title: Variable patterns of ectopic mineralization in Enpp1asj-2J mice, a model for generalized arterial calcification of infancy.
Volume: 7
Issue: 51
Pages: 83837-83842
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Publication
27959908 | J:251638
First Author: Tian C
Year: 2016
Journal: PLoS One
Title: Ectopic Mineralization and Conductive Hearing Loss in Enpp1asj Mutant Mice, a New Model for Otitis Media and Tympanosclerosis.
Volume: 11
Issue: 12
Pages: e0168159
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Publication
12082181 | J:77731
First Author: Hessle L
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Tissue-nonspecific alkaline phosphatase and plasma cell membrane glycoprotein-1 are central antagonistic regulators of bone mineralization.
Volume: 99
Issue: 14
Pages: 9445-9
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Publication
28701330 | J:266816
First Author: Dedinszki D
Year: 2017
Journal: EMBO Mol Med
Title: Oral administration of pyrophosphate inhibits connective tissue calcification.
Volume: 9
Issue: 11
Pages: 1463-1470
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Publication
15920156 | J:98814
First Author: Anderson HC
Year: 2005
Journal: Am J Pathol
Title: Sustained osteomalacia of long bones despite major improvement in other hypophosphatasia-related mineral deficits in tissue nonspecific alkaline phosphatase/nucleotide pyrophosphatase phosphodiesterase 1 double-deficient mice.
Volume: 166
Issue: 6
Pages: 1711-20
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Publication
21930712 | J:178159
First Author: Nam HK
Year: 2011
Journal: J Biol Chem
Title: Ectonucleotide pyrophosphatase/phosphodiesterase-1 (ENPP1) protein regulates osteoblast differentiation.
Volume: 286
Issue: 45
Pages: 39059-71
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Publication
24732453 | J:211672
First Author: Li Q
Year: 2014
Journal: Lab Invest
Title: Genetic modulation of nephrocalcinosis in mouse models of ectopic mineralization: the Abcc6(tm1Jfk) and Enpp1(asj) mutant mice.
Volume: 94
Issue: 6
Pages: 623-32
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Publication
28652107 | J:252205
First Author: Zhao J
Year: 2017
Journal: J Invest Dermatol
Title: Plasma PPi Deficiency Is the Major, but Not?the Exclusive, Cause of Ectopic Mineralization in an Abcc6(-/-) Mouse Model of PXE.
Volume: 137
Issue: 11
Pages: 2336-2343
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Publication
41553309 | J:378495
First Author: Ma Z
Year: 2026
Journal: Gastroenterology
Title: ENPP1-Regulated Extracellular Purine Metabolism Drives Pancreatitis-Mediated Pancreatic Cancer.
Volume: 170
Issue: 4
Pages: 735-752
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Publication
33356859 | J:340126
First Author: Nagasaki A
Year: 2021
Journal: J Dent Res
Title: Ablation of Pyrophosphate Regulators Promotes Periodontal Regeneration.
Volume: 100
Issue: 6
Pages: 639-647
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Publication
15039209 | J:89120
First Author: Harmey D
Year: 2004
Journal: Am J Pathol
Title: Concerted regulation of inorganic pyrophosphate and osteopontin by akp2, enpp1, and ank: an integrated model of the pathogenesis of mineralization disorders.
Volume: 164
Issue: 4
Pages: 1199-209
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Publication
32224162 | J:292261
 
First Author: Chu EY
Year: 2020
Journal: Bone
Title: Genetic and pharmacologic modulation of cementogenesis via pyrophosphate regulators.
Volume: 136
Pages: 115329
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Publication
20200993 | J:233132
First Author: Neunaber C
Year: 2010
Journal: J Bone Miner Res
Title: Increased trabecular bone formation in mice lacking the growth factor midkine.
Volume: 25
Issue: 8
Pages: 1724-35
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Publication
11856874 | J:75536
First Author: Koshizuka Y
Year: 2001
Journal: Cytogenet Cell Genet
Title: Isolation of novel mouse genes associated with ectopic ossification by differential display method using ttw, a mouse model for ectopic ossification.
Volume: 94
Issue: 3-4
Pages: 163-8
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Publication
31059863 | J:279653
 
First Author: Choi H
Year: 2019
Journal: Bone
Title: Antagonistic interactions between osterix and pyrophosphate during cementum formation.
Volume: 125
Pages: 8-15
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Publication
31064775 | J:276880
 
First Author: Motch Perrine SM
Year: 2019
Journal: Dis Model Mech
Title: Mandibular dysmorphology due to abnormal embryonic osteogenesis in FGFR2-related craniosynostosis mice.
Volume: 12
Issue: 5
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Publication
21810932 | J:182179
First Author: Pan W
Year: 2011
Journal: Am J Physiol Endocrinol Metab
Title: Metabolic consequences of ENPP1 overexpression in adipose tissue.
Volume: 301
Issue: 5
Pages: E901-11
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Protein Coding Gene
MGP_CAROLIEiJ_G0015189 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
ENSMUSG00200009541 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00195013316 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00220010540 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00180016642 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00175023901 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_97370 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00215009785 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSTCUG00005012915 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00210023018 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00185006457 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00205009369 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00230010270 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSUMUG00000015844 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00190015112 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00225030171 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSLUMG00010009111 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSIUOG00005029473 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0023811 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
ENSMSPG00010014324 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
3104326 | J:21444
First Author: van Driel IR
Year: 1987
Journal: J Biol Chem
Title: Plasma cell membrane glycoprotein PC-1. Primary structure deduced from cDNA clones.
Volume: 262
Issue: 10
Pages: 4882-7
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Publication
8223581 | J:133038
First Author: Belli SI
Year: 1993
Journal: Eur J Biochem
Title: Identification and characterization of a soluble form of the plasma cell membrane glycoprotein PC-1 (5'-nucleotide phosphodiesterase).
Volume: 217
Issue: 1
Pages: 421-8
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Publication
3001713 | J:8145
First Author: van Driel IR
Year: 1985
Journal: Proc Natl Acad Sci U S A
Title: Murine plasma cell membrane antigen PC-1: molecular cloning of cDNA and analysis of expression.
Volume: 82
Issue: 24
Pages: 8619-23
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Publication
3917281 | J:384526
First Author: Stearne PA
Year: 1985
Journal: J Immunol
Title: The murine plasma cell antigen PC-1: purification and partial amino acid sequence.
Volume: 134
Issue: 1
Pages: 443-8
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Publication
2211644 | J:10767
First Author: Buckley MF
Year: 1990
Journal: J Biol Chem
Title: Plasma cell membrane glycoprotein PC-1. cDNA cloning of the human molecule, amino acid sequence, and chromosomal location.
Volume: 265
Issue: 29
Pages: 17506-11
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Publication
9662402 | J:48527
First Author: Okawa A
Year: 1998
Journal: Nat Genet
Title: Mutation in Npps in a mouse model of ossification of the posterior longitudinal ligament of the spine.
Volume: 19
Issue: 3
Pages: 271-3
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Publication
11598187 | J:384314
First Author: Bello V
Year: 2001
Journal: Mol Biol Cell
Title: Characterization of a di-leucine-based signal in the cytoplasmic tail of the nucleotide-pyrophosphatase NPP1 that mediates basolateral targeting but not endocytosis.
Volume: 12
Issue: 10
Pages: 3004-15
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Publication
12533192 | J:83030
First Author: Gijsbers R
Year: 2003
Journal: Biochem J
Title: Functional characterization of the non-catalytic ectodomains of the nucleotide pyrophosphatase/phosphodiesterase NPP1.
Volume: 371
Issue: Pt 2
Pages: 321-30
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Publication
15075217 | J:383861
First Author: Vaingankar SM
Year: 2004
Journal: Am J Physiol Cell Physiol
Title: Subcellular targeting and function of osteoblast nucleotide pyrophosphatase phosphodiesterase 1.
Volume: 286
Issue: 5
Pages: C1177-87
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Publication
25260930 | J:218042
 
First Author: Hajjawi MO
Year: 2014
Journal: Bone
Title: Mineralisation of collagen rich soft tissues and osteocyte lacunae in Enpp1(-/-) mice.
Volume: 69
Pages: 139-47
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Publication
23041369 | J:247392
First Author: Jansen S
Year: 2012
Journal: Structure
Title: Structure of NPP1, an ectonucleotide pyrophosphatase/phosphodiesterase involved in tissue calcification.
Volume: 20
Issue: 11
Pages: 1948-59
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Publication
7344126 | J:37369
 
First Author: Hosoda Y
Year: 1981
Journal: Ryumachi
Title: A new breed of mouse showing multiple osteochondral lesions--twy mouse.
Volume: 21 Suppl
Pages: 157-64
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Publication
- | J:13296
First Author: Kojimahara K
Year: 1993
Journal: Keio J Med
Title: Pathophysiological and biochemical studies on the vertebral and spinal cord lesions of Twy mouse (Mouse with genetic osteochondral abnormalities).
Volume: 42
Issue: 2
Pages: 87
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Publication
9457678 | J:45878
First Author: Okawa A
Year: 1998
Journal: Mamm Genome
Title: Mapping of a gene responsible for twy (tip-toe walking Yoshimura), a mouse model of ossification of the posterior longitudinal ligament of the spine (OPLL).
Volume: 9
Issue: 2
Pages: 155-6
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Publication
8750545 | J:111133
First Author: Baba H
Year: 1996
Journal: J Neurol
Title: Quantitative analysis of the spinal cord motoneuron under chronic compression: an experimental observation in the mouse.
Volume: 243
Issue: 2
Pages: 109-16
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Publication
9392042 | J:46348
First Author: Yato Y
Year: 1997
Journal: Spinal Cord
Title: Decreased choline acetyltransferase activity in the murine spinal cord motoneurons under chronic mechanical compression.
Volume: 35
Issue: 11
Pages: 729-34
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Publication
21935678 | J:285488
First Author: Uchida K
Year: 2012
Journal: Eur Spine J
Title: Apoptosis of neurons and oligodendrocytes in the spinal cord of spinal hyperostotic mouse (twy/twy): possible pathomechanism of human cervical compressive myelopathy.
Volume: 21
Issue: 3
Pages: 490-7
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Publication
9541520 | J:113073
First Author: Kobayashi Y
Year: 1998
Journal: Calcif Tissue Int
Title: Regional variations in the progression of bone loss in two different mouse osteopenia models.
Volume: 62
Issue: 5
Pages: 426-36
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Publication
9359030 | J:43357
First Author: Baba H
Year: 1997
Journal: Eur J Histochem
Title: Potential role of streptozotocin in enhancing ossification of the posterior longitudinal ligament of the cervical spine in the hereditary spinal hyperostotic mouse (twy/twy).
Volume: 41
Issue: 3
Pages: 191-202
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Publication
- | J:14284
 
First Author: Esaki K
Year: 1990
Journal: Mouse Genome
Title: Tip-toe walking (ttw).
Volume: 86
Pages: 242
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Publication
23717624 | J:200715
First Author: Hirai T
Year: 2013
Journal: PLoS One
Title: The prevalence and phenotype of activated microglia/macrophages within the spinal cord of the hyperostotic mouse (twy/twy) changes in response to chronic progressive spinal cord compression: implications for human cervical compressive myelopathy.
Volume: 8
Issue: 5
Pages: e64528
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Publication
9685524 | J:49368
First Author: Ohtsuki T
Year: 1998
Journal: Calcif Tissue Int
Title: Gene expression of noncollagenous bone matrix proteins in the limb joints and intervertebral disks of the twy mouse.
Volume: 63
Issue: 2
Pages: 167-72
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Publication
31666661 | J:284238
First Author: Takeura N
Year: 2019
Journal: Sci Rep
Title: Role of macrophages and activated microglia in neuropathic pain associated with chronic progressive spinal cord compression.
Volume: 9
Issue: 1
Pages: 15656
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Publication
8055108 | J:19124
First Author: Sakamoto M
Year: 1994
Journal: Pathol Int
Title: Arthritis and ankylosis in twy mice with hereditary multiple osteochondral lesions: with special reference to calcium deposition.
Volume: 44
Issue: 6
Pages: 420-7
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Publication
9840350 | J:53629
First Author: Uchida K
Year: 1998
Journal: J Neurol
Title: Histological investigation of spinal cord lesions in the spinal hyperostotic mouse (twy/twy): morphological changes in anterior horn cells and immunoreactivity to neurotropic factors.
Volume: 245
Issue: 12
Pages: 781-93
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Publication
25368121 | J:217417
First Author: Huesa C
Year: 2014
Journal: Dis Model Mech
Title: Deficiency of the bone mineralization inhibitor NPP1 protects mice against obesity and diabetes.
Volume: 7
Issue: 12
Pages: 1341-50
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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