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Search results 1 to 100 out of 369 for Ern1

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0.077s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: chicken
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Miyoshi K
Year: 2000
Journal: Brain Res Mol Brain Res
Title: Characterization of mouse Ire1 alpha: cloning, mRNA localization in the brain and functional analysis in a neural cell line.
Volume: 85
Issue: 1-2
Pages: 68-76
Publication  
First Author: Sanches M
Year: 2014
Journal: Nat Commun
Title: Structure and mechanism of action of the hydroxy-aryl-aldehyde class of IRE1 endoribonuclease inhibitors.
Volume: 5
Pages: 4202
Publication
First Author: Zhang K
Year: 2005
Journal: J Clin Invest
Title: The unfolded protein response sensor IRE1alpha is required at 2 distinct steps in B cell lymphopoiesis.
Volume: 115
Issue: 2
Pages: 268-81
Publication
First Author: Hassler JR
Year: 2015
Journal: PLoS Biol
Title: The IRE1α/XBP1s Pathway Is Essential for the Glucose Response and Protection of β Cells.
Volume: 13
Issue: 10
Pages: e1002277
Publication
First Author: Zhang K
Year: 2011
Journal: EMBO J
Title: The unfolded protein response transducer IRE1α prevents ER stress-induced hepatic steatosis.
Volume: 30
Issue: 7
Pages: 1357-75
Publication
First Author: Abuaita BH
Year: 2021
Journal: J Immunol
Title: The IRE1α Stress Signaling Axis Is a Key Regulator of Neutrophil Antimicrobial Effector Function.
Volume: 207
Issue: 1
Pages: 210-220
Publication
First Author: Dufey E
Year: 2020
Journal: Nat Commun
Title: Genotoxic stress triggers the activation of IRE1α-dependent RNA decay to modulate the DNA damage response.
Volume: 11
Issue: 1
Pages: 2401
Publication
First Author: Carreras-Sureda A
Year: 2019
Journal: Nat Cell Biol
Title: Non-canonical function of IRE1α determines mitochondria-associated endoplasmic reticulum composition to control calcium transfer and bioenergetics.
Volume: 21
Issue: 6
Pages: 755-767
Publication
First Author: Son J
Year: 2022
Journal: J Invest Dermatol
Title: The Endoplasmic Reticulum Stress Sensor IRE1α Regulates the UV DNA Repair Response through the Control of Intracellular Calcium Homeostasis.
Volume: 142
Issue: 6
Pages: 1682-1691.e7
Publication  
First Author: Medel B
Year: 2018
Journal: Front Immunol
Title: IRE1α Activation in Bone Marrow-Derived Dendritic Cells Modulates Innate Recognition of Melanoma Cells and Favors CD8+ T Cell Priming.
Volume: 9
Pages: 3050
Publication
First Author: Meares GP
Year: 2011
Journal: Mol Cell Biol
Title: IRE1-dependent activation of AMPK in response to nitric oxide.
Volume: 31
Issue: 21
Pages: 4286-97
Publication  
First Author: Wang JM
Year: 2018
Journal: Sci Signal
Title: IRE1α prevents hepatic steatosis by processing and promoting the degradation of select microRNAs.
Volume: 11
Issue: 530
Publication
First Author: Zhang HS
Year: 2015
Journal: J Biol Chem
Title: The Endoplasmic Reticulum Stress Sensor IRE1α in Intestinal Epithelial Cells Is Essential for Protecting against Colitis.
Volume: 290
Issue: 24
Pages: 15327-36
Publication
First Author: Li XX
Year: 2017
Journal: Oncogene
Title: Knockdown of IRE1α inhibits colonic tumorigenesis through decreasing β-catenin and IRE1α targeting suppresses colon cancer cells.
Volume: 36
Issue: 48
Pages: 6738-6746
Publication    
First Author: Foley KP
Year: 2021
Journal: J Biol Chem
Title: Inflammation promotes adipocyte lipolysis via IRE1 kinase.
Pages: 100440
Publication
First Author: Li Y
Year: 2022
Journal: J Biol Chem
Title: Phosphorylation at Ser724 of the ER stress sensor IRE1α governs its activation state and limits ER stress-induced hepatosteatosis.
Volume: 298
Issue: 6
Pages: 101997
Publication
First Author: Marcu MG
Year: 2002
Journal: Mol Cell Biol
Title: Heat shock protein 90 modulates the unfolded protein response by stabilizing IRE1alpha.
Volume: 22
Issue: 24
Pages: 8506-13
Publication
First Author: Ogata M
Year: 2006
Journal: Mol Cell Biol
Title: Autophagy is activated for cell survival after endoplasmic reticulum stress.
Volume: 26
Issue: 24
Pages: 9220-31
Publication
First Author: Goffin L
Year: 2006
Journal: Mol Biol Cell
Title: The unfolded protein response transducer Ire1p contains a nuclear localization sequence recognized by multiple beta importins.
Volume: 17
Issue: 12
Pages: 5309-23
Publication
First Author: Lin JH
Year: 2007
Journal: Science
Title: IRE1 signaling affects cell fate during the unfolded protein response.
Volume: 318
Issue: 5852
Pages: 944-9
Publication
First Author: Han D
Year: 2008
Journal: Biochem Biophys Res Commun
Title: A kinase inhibitor activates the IRE1alpha RNase to confer cytoprotection against ER stress.
Volume: 365
Issue: 4
Pages: 777-83
Publication
First Author: Auf G
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Inositol-requiring enzyme 1alpha is a key regulator of angiogenesis and invasion in malignant glioma.
Volume: 107
Issue: 35
Pages: 15553-8
Publication
First Author: Li H
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Mammalian endoplasmic reticulum stress sensor IRE1 signals by dynamic clustering.
Volume: 107
Issue: 37
Pages: 16113-8
Publication
First Author: Kitai Y
Year: 2013
Journal: Genes Cells
Title: Membrane lipid saturation activates IRE1α without inducing clustering.
Volume: 18
Issue: 9
Pages: 798-809
Publication
First Author: Pierre N
Year: 2014
Journal: Biochem Biophys Res Commun
Title: Activation of ER stress by hydrogen peroxide in C2C12 myotubes.
Volume: 450
Issue: 1
Pages: 459-63
Publication
First Author: Shan B
Year: 2017
Journal: Nat Immunol
Title: The metabolic ER stress sensor IRE1α suppresses alternative activation of macrophages and impairs energy expenditure in obesity.
Volume: 18
Issue: 5
Pages: 519-529
Publication
First Author: Homma T
Year: 2016
Journal: Exp Cell Res
Title: Heat stress promotes the down-regulation of IRE1α in cells: An atypical modulation of the UPR pathway.
Volume: 349
Issue: 1
Pages: 128-138
Publication  
First Author: Studencka-Turski M
Year: 2019
Journal: Front Immunol
Title: Molecular Insight Into the IRE1α-Mediated Type I Interferon Response Induced by Proteasome Impairment in Myeloid Cells of the Brain.
Volume: 10
Pages: 2900
Publication  
First Author: Sule G
Year: 2021
Journal: J Clin Invest
Title: Endoplasmic reticulum stress sensor IRE1α propels neutrophil hyperactivity in lupus.
Volume: 131
Issue: 7
Publication  
First Author: Chalmers FE
Year: 2022
Journal: Dev Biol
Title: The unfolded protein response gene Ire1α is required for tissue renewal and normal differentiation in the mouse tongue and esophagus.
Volume: 492
Pages: 59-70
Publication
First Author: Bracchi-Ricard V
Year: 2023
Journal: FASEB J
Title: Increased activity of IRE1 improves the clinical presentation of EAE.
Volume: 37
Issue: 12
Pages: e23283
GXD Expression      
Probe: MGI:3846676
Assay Type: RT-PCR
Annotation Date: 2009-06-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3846680
Age: postnatal week 8
Specimen Label: Brain
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3846676
Assay Type: RT-PCR
Annotation Date: 2009-06-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:3846680
Age: postnatal week 8
Specimen Label: Lung
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3846676
Assay Type: RT-PCR
Annotation Date: 2009-06-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3846680
Age: postnatal week 8
Specimen Label: Heart
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:3846676
Assay Type: RT-PCR
Annotation Date: 2009-06-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:3846680
Age: postnatal week 8
Specimen Label: Thymus
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:3846676
Assay Type: RT-PCR
Annotation Date: 2009-06-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:3846680
Age: postnatal week 8
Specimen Label: Spleen
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:3846676
Assay Type: RT-PCR
Annotation Date: 2009-06-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3846680
Age: postnatal week 8
Specimen Label: Liver
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:3846676
Assay Type: RT-PCR
Annotation Date: 2009-06-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:3846680
Age: postnatal week 8
Specimen Label: Kidney
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:3846676
Assay Type: RT-PCR
Annotation Date: 2009-06-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3287428
Stage: TS28
Assay Id: MGI:3846680
Age: postnatal week 8
Specimen Label: Intestine
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:3846676
Assay Type: RT-PCR
Annotation Date: 2009-06-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3846680
Age: postnatal week 8
Specimen Label: Testis
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:3846676
Assay Type: RT-PCR
Annotation Date: 2009-06-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:3846680
Age: postnatal week 8
Specimen Label: Skeletal Muscle
Detected: true
Specimen Num: 10
GXD Expression      
Probe: MGI:3846676
Assay Type: RT-PCR
Annotation Date: 2009-06-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689422
Stage: TS22
Assay Id: MGI:3846681
Age: embryonic day 14.0
Specimen Label: E14
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3846676
Assay Type: RT-PCR
Annotation Date: 2009-06-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:3846681
Age: embryonic day 18.0
Specimen Label: E18
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3846676
Assay Type: RT-PCR
Annotation Date: 2009-06-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:3846681
Age: postnatal day 1
Specimen Label: P1
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:3846676
Assay Type: RT-PCR
Annotation Date: 2009-06-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3846681
Age: postnatal day 7
Specimen Label: P7
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:3846676
Assay Type: RT-PCR
Annotation Date: 2009-06-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3846681
Age: postnatal day 14
Specimen Label: P14
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:3846676
Assay Type: RT-PCR
Annotation Date: 2009-06-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3846681
Age: postnatal week 8
Specimen Label: 8W
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6423152
Assay Type: Western blot
Annotation Date: 2020-05-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6423457
Age: postnatal month 1
Image: 7
Specimen Label: Con
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6423152
Assay Type: Western blot
Annotation Date: 2020-05-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6423457
Age: postnatal month 1
Image: 7
Specimen Label: Con
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6423152
Assay Type: Western blot
Annotation Date: 2020-05-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6423457
Age: postnatal month 1
Image: 7
Specimen Label: Con
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6423152
Assay Type: Western blot
Annotation Date: 2020-05-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6423457
Age: postnatal month 1
Image: 7
Specimen Label: CKO
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6423152
Assay Type: Western blot
Annotation Date: 2020-05-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6423457
Age: postnatal month 1
Image: 7
Specimen Label: CKO
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6423152
Assay Type: Western blot
Annotation Date: 2020-05-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6423457
Age: postnatal month 1
Image: 7
Specimen Label: CKO
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:6459940
Assay Type: RT-PCR
Annotation Date: 2020-10-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3525121
Stage: TS21
Assay Id: MGI:6459958
Age: embryonic day 13.5
Specimen Label: E13.5
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:6459940
Assay Type: RT-PCR
Annotation Date: 2020-10-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1920923
Stage: TS23
Assay Id: MGI:6459958
Age: embryonic day 15.5
Specimen Label: E15.5
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:6459940
Assay Type: RT-PCR
Annotation Date: 2020-10-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1920927
Stage: TS27
Assay Id: MGI:6459958
Age: postnatal day 0
Specimen Label: P0
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6506001
Assay Type: RT-PCR
Annotation Date: 2021-02-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3674122
Stage: TS22
Assay Id: MGI:6506021
Age: embryonic day 14.5
Image: 1
Specimen Label: Cap
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6506001
Assay Type: RT-PCR
Annotation Date: 2021-02-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3674224
Stage: TS24
Assay Id: MGI:6506021
Age: embryonic day 16.5
Image: 1
Specimen Label: Bell
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6506001
Assay Type: RT-PCR
Annotation Date: 2021-02-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3289727
Stage: TS27
Assay Id: MGI:6506021
Age: postnatal day 0
Image: 1
Specimen Label: Secretory
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:6509661
Assay Type: RT-PCR
Annotation Date: 2021-03-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6510257
Age: postnatal month 2
Specimen Label: WT 2MO
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:6509661
Assay Type: RT-PCR
Annotation Date: 2021-03-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6510257
Age: postnatal month 2
Specimen Label: DKO 2 MO
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:6509661
Assay Type: RT-PCR
Annotation Date: 2021-03-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6510257
Age: postnatal month 7
Specimen Label: WT 7MO
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:6509661
Assay Type: RT-PCR
Annotation Date: 2021-03-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6510257
Age: postnatal month 7
Specimen Label: DKO 7MO
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:7621383
Assay Type: RT-PCR
Annotation Date: 2024-04-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754420
Stage: TS20
Assay Id: MGI:7621395
Age: embryonic day 12.5
Specimen Label: E12.5
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7621383
Assay Type: RT-PCR
Annotation Date: 2024-04-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754422
Stage: TS22
Assay Id: MGI:7621395
Age: embryonic day 14.5
Specimen Label: E14.5
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7621383
Assay Type: RT-PCR
Annotation Date: 2024-04-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754425
Stage: TS25
Assay Id: MGI:7621395
Age: embryonic day 17.5
Specimen Label: E17.5
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:7621383
Assay Type: RT-PCR
Annotation Date: 2024-04-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754427
Stage: TS27
Assay Id: MGI:7621395
Age: postnatal day 0
Specimen Label: P0
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:7621383
Assay Type: RT-PCR
Annotation Date: 2024-04-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:7621395
Age: postnatal day 7.5
Specimen Label: P7.5
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:7621383
Assay Type: RT-PCR
Annotation Date: 2024-04-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:7621395
Age: postnatal day 15
Specimen Label: P15
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:7621383
Assay Type: RT-PCR
Annotation Date: 2024-04-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:7621395
Age: postnatal adult
Specimen Label: AD
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:7621390
Assay Type: Western blot
Annotation Date: 2024-04-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754420
Stage: TS20
Assay Id: MGI:7621398
Age: embryonic day 12.5
Specimen Label: E12.5
Detected: true
Specimen Num: 1