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Search results 1 to 100 out of 351 for Faah

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0.037s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Protein Domain
Type: Family
Description: Fatty-acid amide hydrolase 1 (FAAH) is a mammalian integral membrane enzyme that degrades the fatty acid amide family of endogenous signalling lipids, which includes the endogenous cannabinoid anandamide and the sleep-inducing substance oleamide [].
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
GXD Expression  
Probe: MGI:981324
Assay Type: RNA in situ
Annotation Date: 2009-01-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3564522
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3825839
Age: embryonic day 14.5
Image: Additional file 4 Faah
Specimen Label: Additional file 4 Faah
Detected: true
Specimen Num: 1
Publication  
First Author: Dincheva I
Year: 2015
Journal: Nat Commun
Title: FAAH genetic variation enhances fronto-amygdala function in mouse and human.
Volume: 6
Pages: 6395
Publication
First Author: Sun X
Year: 2009
Journal: Biol Reprod
Title: Genetic loss of Faah compromises male fertility in mice.
Volume: 80
Issue: 2
Pages: 235-42
Publication
First Author: Basavarajappa BS
Year: 2006
Journal: Neuropharmacology
Title: Increased ethanol consumption and preference and decreased ethanol sensitivity in female FAAH knockout mice.
Volume: 50
Issue: 7
Pages: 834-44
Publication
First Author: Vaitheesvaran B
Year: 2012
Journal: PLoS One
Title: Peripheral effects of FAAH deficiency on fuel and energy homeostasis: role of dysregulated lysine acetylation.
Volume: 7
Issue: 3
Pages: e33717
Publication
First Author: Long JZ
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Dual blockade of FAAH and MAGL identifies behavioral processes regulated by endocannabinoid crosstalk in vivo.
Volume: 106
Issue: 48
Pages: 20270-5
Publication
First Author: Ortega-Gutiérrez S
Year: 2004
Journal: Biochemistry
Title: Comparison of anandamide transport in FAAH wild-type and knockout neurons: evidence for contributions by both FAAH and the CB1 receptor to anandamide uptake.
Volume: 43
Issue: 25
Pages: 8184-90
Protein
Organism: Mus musculus
Length: 579  
Fragment?: false
Protein
Organism: Mus musculus
Length: 745  
Fragment?: false
Protein
Organism: Mus musculus
Length: 65  
Fragment?: true
Protein
Organism: Mus musculus
Length: 579  
Fragment?: false
Protein
Organism: Mus musculus
Length: 534  
Fragment?: true
Publication  
First Author: McKinney MK
Year: 2005
Journal: Annu Rev Biochem
Title: Structure and function of fatty acid amide hydrolase.
Volume: 74
Pages: 411-32
GXD Expression    
Probe: MGI:6172371
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6190248
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Faah
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6172371
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6190248
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Faah
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6172371
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6190248
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Faah
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6172371
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6190248
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Faah
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6172371
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190248
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Faah
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6172371
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190248
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Faah
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6172371
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190248
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Faah
Detected: true
Specimen Num: 7
Publication
First Author: Giang DK
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: Molecular characterization of human and mouse fatty acid amide hydrolases.
Volume: 94
Issue: 6
Pages: 2238-42
Publication
First Author: Saghatelian A
Year: 2004
Journal: Biochemistry
Title: Assignment of endogenous substrates to enzymes by global metabolite profiling.
Volume: 43
Issue: 45
Pages: 14332-9
Publication
First Author: Burgdorf CE
Year: 2020
Journal: Sci Adv
Title: Endocannabinoid genetic variation enhances vulnerability to THC reward in adolescent female mice.
Volume: 6
Issue: 7
Pages: eaay1502
Publication
First Author: Brown WH
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Fatty acid amide hydrolase ablation promotes ectopic lipid storage and insulin resistance due to centrally mediated hypothyroidism.
Volume: 109
Issue: 37
Pages: 14966-71
Publication
First Author: Dainese E
Year: 2014
Journal: Biochem J
Title: Membrane lipids are key modulators of the endocannabinoid-hydrolase FAAH.
Volume: 457
Issue: 3
Pages: 463-72
Publication
First Author: Vázquez C
Year: 2015
Journal: Neurobiol Aging
Title: Endocannabinoid regulation of amyloid-induced neuroinflammation.
Volume: 36
Issue: 11
Pages: 3008-3019
Publication
First Author: Cravatt BF
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: Supersensitivity to anandamide and enhanced endogenous cannabinoid signaling in mice lacking fatty acid amide hydrolase.
Volume: 98
Issue: 16
Pages: 9371-6
Publication
First Author: Long JZ
Year: 2011
Journal: J Lipid Res
Title: An anatomical and temporal portrait of physiological substrates for fatty acid amide hydrolase.
Volume: 52
Issue: 2
Pages: 337-44
Publication
First Author: Egertová M
Year: 2004
Journal: J Chem Neuroanat
Title: Fatty acid amide hydrolase in brain ventricular epithelium: mutually exclusive patterns of expression in mouse and rat.
Volume: 28
Issue: 3
Pages: 171-81
Publication
First Author: Wise LE
Year: 2009
Journal: Neurobiol Learn Mem
Title: Fatty acid amide hydrolase (FAAH) knockout mice exhibit enhanced acquisition of an aversive, but not of an appetitive, Barnes maze task.
Volume: 92
Issue: 4
Pages: 597-601
Publication  
First Author: Wang ZY
Year: 2015
Journal: Neurosci Lett
Title: Activation of cannabinoid receptor 1 inhibits increased bladder activity induced by nerve growth factor.
Volume: 589
Pages: 19-24
Publication
First Author: Cravatt BF
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Functional disassociation of the central and peripheral fatty acid amide signaling systems.
Volume: 101
Issue: 29
Pages: 10821-6
Publication
First Author: Clement AB
Year: 2003
Journal: J Neurosci
Title: Increased seizure susceptibility and proconvulsant activity of anandamide in mice lacking fatty acid amide hydrolase.
Volume: 23
Issue: 9
Pages: 3916-23
Publication
First Author: Webb M
Year: 2008
Journal: Neurosci Lett
Title: Genetic deletion of Fatty Acid Amide Hydrolase results in improved long-term outcome in chronic autoimmune encephalitis.
Volume: 439
Issue: 1
Pages: 106-10
Publication
First Author: Mukhopadhyay P
Year: 2011
Journal: Free Radic Biol Med
Title: Fatty acid amide hydrolase is a key regulator of endocannabinoid-induced myocardial tissue injury.
Volume: 50
Issue: 1
Pages: 179-95
Publication
First Author: Patel S
Year: 2005
Journal: J Lipid Res
Title: The postmortal accumulation of brain N-arachidonylethanolamine (anandamide) is dependent upon fatty acid amide hydrolase activity.
Volume: 46
Issue: 2
Pages: 342-9
Publication  
First Author: Ativie F
Year: 2015
Journal: Life Sci
Title: Enhanced microglial activity in FAAH(-/-) animals.
Volume: 138
Pages: 52-6
Publication
First Author: Wang H
Year: 2006
Journal: J Clin Invest
Title: Fatty acid amide hydrolase deficiency limits early pregnancy events.
Volume: 116
Issue: 8
Pages: 2122-31
Publication
First Author: Siegmund SV
Year: 2006
Journal: J Biol Chem
Title: Fatty acid amide hydrolase determines anandamide-induced cell death in the liver.
Volume: 281
Issue: 15
Pages: 10431-8
Publication
First Author: Lichtman AH
Year: 2004
Journal: Pain
Title: Mice lacking fatty acid amide hydrolase exhibit a cannabinoid receptor-mediated phenotypic hypoalgesia.
Volume: 109
Issue: 3
Pages: 319-27
Publication
First Author: Lenglet S
Year: 2013
Journal: Arterioscler Thromb Vasc Biol
Title: Fatty acid amide hydrolase deficiency enhances intraplaque neutrophil recruitment in atherosclerotic mice.
Volume: 33
Issue: 2
Pages: 215-23
Publication
First Author: Ahmad A
Year: 2017
Journal: Am J Physiol Renal Physiol
Title: Stimulation of diuresis and natriuresis by renomedullary infusion of a dual inhibitor of fatty acid amide hydrolase and monoacylglycerol lipase.
Volume: 313
Issue: 5
Pages: F1068-F1076
Publication
First Author: Pacher P
Year: 2005
Journal: Am J Physiol Heart Circ Physiol
Title: Hemodynamic profile, responsiveness to anandamide, and baroreflex sensitivity of mice lacking fatty acid amide hydrolase.
Volume: 289
Issue: 2
Pages: H533-41
Publication
First Author: Saghatelian A
Year: 2006
Journal: Biochemistry
Title: A FAAH-regulated class of N-acyl taurines that activates TRP ion channels.
Volume: 45
Issue: 30
Pages: 9007-15
Publication
First Author: Moreira FA
Year: 2008
Journal: Neuropharmacology
Title: Reduced anxiety-like behaviour induced by genetic and pharmacological inhibition of the endocannabinoid-degrading enzyme fatty acid amide hydrolase (FAAH) is mediated by CB1 receptors.
Volume: 54
Issue: 1
Pages: 141-50
Publication
First Author: Gee DG
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Individual differences in frontolimbic circuitry and anxiety emerge with adolescent changes in endocannabinoid signaling across species.
Volume: 113
Issue: 16
Pages: 4500-5
Publication
First Author: Rashid MA
Year: 2013
Journal: J Neurochem
Title: N-Docosahexaenoylethanolamine is a potent neurogenic factor for neural stem cell differentiation.
Volume: 125
Issue: 6
Pages: 869-84
Publication
First Author: Yaghootfam C
Year: 2021
Journal: J Biol Chem
Title: Deletion of fatty acid amide hydrolase reduces lyso-sulfatide levels but exacerbates metachromatic leukodystrophy in mice.
Volume: 297
Issue: 3
Pages: 101064
Publication
First Author: Bilsland LG
Year: 2006
Journal: FASEB J
Title: Increasing cannabinoid levels by pharmacological and genetic manipulation delay disease progression in SOD1 mice.
Volume: 20
Issue: 7
Pages: 1003-5
Publication  
First Author: Helfand AI
Year: 2017
Journal: Int J Mol Sci
Title: Cannabinoid Receptor 1 and Fatty Acid Amide Hydrolase Contribute to Operant Sensation Seeking in Mice.
Volume: 18
Issue: 8
Publication    
First Author: Carey LM
Year: 2016
Journal: Mol Pain
Title: A pro-nociceptive phenotype unmasked in mice lacking fatty-acid amide hydrolase.
Volume: 12
Publication
First Author: Lin L
Year: 2017
Journal: J Neurochem
Title: Fatty acid amide hydrolase (FAAH) regulates hypercapnia/ischemia-induced increases in n-acylethanolamines in mouse brain.
Volume: 142
Issue: 5
Pages: 662-671
Publication
First Author: Bátkai S
Year: 2007
Journal: Am J Physiol Heart Circ Physiol
Title: Decreased age-related cardiac dysfunction, myocardial nitrative stress, inflammatory gene expression, and apoptosis in mice lacking fatty acid amide hydrolase.
Volume: 293
Issue: 2
Pages: H909-18
Publication
First Author: Ahmad A
Year: 2018
Journal: Am J Physiol Renal Physiol
Title: Modulation of mean arterial pressure and diuresis by renomedullary infusion of a selective inhibitor of fatty acid amide hydrolase.
Volume: 315
Issue: 4
Pages: F967-F976
Publication
First Author: Paria BC
Year: 1999
Journal: Biol Reprod
Title: Fatty-acid amide hydrolase is expressed in the mouse uterus and embryo during the periimplantation period.
Volume: 60
Issue: 5
Pages: 1151-7
Publication
First Author: Wenzel D
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Endocannabinoid anandamide mediates hypoxic pulmonary vasoconstriction.
Volume: 110
Issue: 46
Pages: 18710-5
Publication
First Author: Alhouayek M
Year: 2017
Journal: Biochim Biophys Acta
Title: N-acylethanolamine-hydrolyzing acid amidase and fatty acid amide hydrolase inhibition differentially affect N-acylethanolamine levels and macrophage activation.
Volume: 1862
Issue: 5
Pages: 474-484
Publication
First Author: Grevengoed TJ
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: N-acyl taurines are endogenous lipid messengers that improve glucose homeostasis.
Volume: 116
Issue: 49
Pages: 24770-24778
Publication
First Author: Freigang S
Year: 2010
Journal: J Clin Invest
Title: Fatty acid amide hydrolase shapes NKT cell responses by influencing the serum transport of lipid antigen in mice.
Volume: 120
Issue: 6
Pages: 1873-84
Publication
First Author: Capasso R
Year: 2005
Journal: Gastroenterology
Title: Fatty acid amide hydrolase controls mouse intestinal motility in vivo.
Volume: 129
Issue: 3
Pages: 941-51
Publication  
First Author: Mallet C
Year: 2010
Journal: PLoS One
Title: TRPV1 in brain is involved in acetaminophen-induced antinociception.
Volume: 5
Issue: 9
Publication
First Author: Lichtman AH
Year: 2002
Journal: J Pharmacol Exp Ther
Title: Pharmacological activity of fatty acid amides is regulated, but not mediated, by fatty acid amide hydrolase in vivo.
Volume: 302
Issue: 1
Pages: 73-9
Publication
First Author: Vinod KY
Year: 2008
Journal: J Neurochem
Title: Manipulation of fatty acid amide hydrolase functional activity alters sensitivity and dependence to ethanol.
Volume: 104
Issue: 1
Pages: 233-43
Publication
First Author: Sun X
Year: 2016
Journal: J Biol Chem
Title: Sustained Endocannabinoid Signaling Compromises Decidual Function and Promotes Inflammation-induced Preterm Birth.
Volume: 291
Issue: 15
Pages: 8231-40
Publication
First Author: Balsevich G
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Role for fatty acid amide hydrolase (FAAH) in the leptin-mediated effects on feeding and energy balance.
Volume: 115
Issue: 29
Pages: 7605-7610
Publication
First Author: Sasso O
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Endogenous N-acyl taurines regulate skin wound healing.
Volume: 113
Issue: 30
Pages: E4397-406
Publication
First Author: Miller S
Year: 2016
Journal: Invest Ophthalmol Vis Sci
Title: Evidence for a GPR18 Role in Diurnal Regulation of Intraocular Pressure.
Volume: 57
Issue: 14
Pages: 6419-6426
Publication
First Author: Siegmund SV
Year: 2013
Journal: Biochem Biophys Res Commun
Title: Fatty acid amide hydrolase but not monoacyl glycerol lipase controls cell death induced by the endocannabinoid 2-arachidonoyl glycerol in hepatic cell populations.
Volume: 437
Issue: 1
Pages: 48-54
Publication
First Author: Benito C
Year: 2012
Journal: Br J Pharmacol
Title: β-Amyloid exacerbates inflammation in astrocytes lacking fatty acid amide hydrolase through a mechanism involving PPAR-α, PPAR-γ and TRPV1, but not CB₁ or CB₂ receptors.
Volume: 166
Issue: 4
Pages: 1474-89
Publication  
First Author: Leishman E
Year: 2016
Journal: Pharmacol Res
Title: Broad impact of deleting endogenous cannabinoid hydrolyzing enzymes and the CB1 cannabinoid receptor on the endogenous cannabinoid-related lipidome in eight regions of the mouse brain.
Volume: 110
Pages: 159-172
Publication
First Author: Wan M
Year: 1998
Journal: Genomics
Title: Conserved chromosomal location and genomic structure of human and mouse fatty-acid amide hydrolase genes and evaluation of clasper as a candidate neurological mutation.
Volume: 54
Issue: 3
Pages: 408-14
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Fowler CJ
Year: 2013
Journal: FEBS J
Title: Transport of endocannabinoids across the plasma membrane and within the cell.
Volume: 280
Issue: 9
Pages: 1895-904
Publication
First Author: Sun X
Year: 2018
Journal: Biol Reprod
Title: Metformin attenuates susceptibility to inflammation-induced preterm birth in mice with higher endocannabinoid levels.
Volume: 98
Issue: 2
Pages: 208-217
Publication
First Author: Wei D
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Endocannabinoid signaling mediates oxytocin-driven social reward.
Volume: 112
Issue: 45
Pages: 14084-9
Publication
First Author: Mulder AM
Year: 2006
Journal: Biochemistry
Title: Endocannabinoid metabolism in the absence of fatty acid amide hydrolase (FAAH): discovery of phosphorylcholine derivatives of N-acyl ethanolamines.
Volume: 45
Issue: 38
Pages: 11267-77
Publication
First Author: Goparaju SK
Year: 1999
Journal: Biochim Biophys Acta
Title: Anandamide amidohydrolase of porcine brain: cDNA cloning, functional expression and site-directed mutagenesis(1).
Volume: 1441
Issue: 1
Pages: 77-84