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Search results 1 to 100 out of 767 for Fasn

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Type Details Score
Gene
Type: gene
Organism: human
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Gene
Type: gene
Organism: frog, western clawed
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Gene
Type: gene
Organism: dog, domestic
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Gene
Type: gene
Organism: rat
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Gene
Type: gene
Organism: chimpanzee
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Gene
Type: gene
Organism: cattle
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Gene
Type: gene
Organism: chicken
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Gene
Type: gene
Organism: zebrafish
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Gene
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
First Author: Gong Z
Year: 2023
Journal: Nat Commun
Title: CircRREB1 mediates lipid metabolism related senescent phenotypes in chondrocytes through FASN post-translational modifications.
Volume: 14
Issue: 1
Pages: 5242
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Publication
First Author: Su M
Year: 2026
Journal: Cell Rep
Title: FASN inactivation-induced progranulin (GRN) expression promotes lysosome-dependent cell death to suppress leukemogenesis.
Volume: 45
Issue: 3
Pages: 117042
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Publication
First Author: Zhang M
Year: 2020
Journal: Biochem Biophys Res Commun
Title: MicroRNA-103 represses hepatic de novo lipogenesis and alleviates NAFLD via targeting FASN and SCD1.
Volume: 524
Issue: 3
Pages: 716-722
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Publication
First Author: Liu XZ
Year: 2026
Journal: Cancer Discov
Title: Targeting the Lipid Metabolism Proteins FASN and GPAM in Alveolar Type II Cells Decreases Lung Metastasis.
Volume: 16
Issue: 7
Pages: 1412-1435
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Publication
First Author: Xie W
Year: 2019
Journal: Biochem Biophys Res Commun
Title: METTL3 inhibits hepatic insulin sensitivity via N6-methyladenosine modification of Fasn mRNA and promoting fatty acid metabolism.
Volume: 518
Issue: 1
Pages: 120-126
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Publication
First Author: Fafi?n-Labora J
Year: 2019
Journal: Cell Death Dis
Title: FASN activity is important for the initial stages of the induction of senescence.
Volume: 10
Issue: 4
Pages: 318
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Publication
First Author: Bastos DC
Year: 2021
Journal: J Pathol
Title: Genetic ablation of FASN attenuates the invasive potential of prostate cancer driven by Pten loss.
Volume: 253
Issue: 3
Pages: 292-303
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Publication  
First Author: Matsukawa T
Year: 2023
Journal: JCI Insight
Title: Hepatic FASN deficiency differentially affects nonalcoholic fatty liver disease and diabetes in mouse obesity models.
Volume: 8
Issue: 17
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Publication
First Author: Jeon BN
Year: 2012
Journal: J Lipid Res
Title: Kr-pok increases FASN expression by modulating the DNA binding of SREBP-1c and Sp1 at the proximal promoter.
Volume: 53
Issue: 4
Pages: 755-66
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Publication
First Author: Suburu J
Year: 2014
Journal: Am J Physiol Endocrinol Metab
Title: Fatty acid synthase is required for mammary gland development and milk production during lactation.
Volume: 306
Issue: 10
Pages: E1132-43
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Publication
First Author: Bruning U
Year: 2018
Journal: Cell Metab
Title: Impairment of Angiogenesis by Fatty Acid Synthase Inhibition Involves mTOR Malonylation.
Volume: 28
Issue: 6
Pages: 866-880.e15
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Publication
First Author: Rowland LA
Year: 2023
Journal: Nat Commun
Title: De novo lipogenesis fuels adipocyte autophagosome and lysosome membrane dynamics.
Volume: 14
Issue: 1
Pages: 1362
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Publication
First Author: Che L
Year: 2017
Journal: Cell Cycle
Title: Oncogene dependent requirement of fatty acid synthase in hepatocellular carcinoma.
Volume: 16
Issue: 6
Pages: 499-507
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Publication  
First Author: Leon-Mercado L
Year: 2025
Journal: Mol Metab
Title: Fatty Acid Synthase regulates glucose and energy homeostasis via POMC neurons and adrenergic signals.
Volume: 98
Pages: 102177
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Publication
First Author: Montani L
Year: 2018
Journal: J Cell Biol
Title: De novo fatty acid synthesis by Schwann cells is essential for peripheral nervous system myelination.
Volume: 217
Issue: 4
Pages: 1353-1368
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Publication
First Author: Schultz K
Year: 2025
Journal: Nature
Title: Snapshots of acyl carrier protein shuttling in human fatty acid synthase.
Volume: 641
Issue: 8062
Pages: 520-528
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Publication
First Author: Jung MY
Year: 2018
Journal: FASEB J
Title: Fatty acid synthase is required for profibrotic TGF-? signaling.
Volume: 32
Issue: 7
Pages: 3803-3815
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Publication
First Author: Shin H
Year: 2023
Journal: Sci Rep
Title: Overexpression of fatty acid synthase attenuates bleomycin induced lung fibrosis by restoring mitochondrial dysfunction in mice.
Volume: 13
Issue: 1
Pages: 9044
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Publication
First Author: Cao K
Year: 2023
Journal: J Pathol
Title: Glycolysis and de novo fatty acid synthesis cooperatively regulate pathological vascular smooth muscle cell phenotypic switching and neointimal hyperplasia.
Volume: 259
Issue: 4
Pages: 388-401
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Publication
First Author: Knobloch M
Year: 2013
Journal: Nature
Title: Metabolic control of adult neural stem cell activity by Fasn-dependent lipogenesis.
Volume: 493
Issue: 7431
Pages: 226-30
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Publication    
First Author: Dimas P
Year: 2019
Journal: Elife
Title: CNS myelination and remyelination depend on fatty acid synthesis by oligodendrocytes.
Volume: 8
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Publication
First Author: Bueno MJ
Year: 2019
Journal: Nat Commun
Title: Essentiality of fatty acid synthase in the 2D to anchorage-independent growth transition in transforming cells.
Volume: 10
Issue: 1
Pages: 5011
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Publication
First Author: Avraham O
Year: 2020
Journal: Nat Commun
Title: Satellite glial cells promote regenerative growth in sensory neurons.
Volume: 11
Issue: 1
Pages: 4891
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Publication
First Author: Nishi-Tatsumi M
Year: 2017
Journal: FEBS Lett
Title: A key role of nuclear factor Y in the refeeding response of fatty acid synthase in adipocytes.
Volume: 591
Issue: 7
Pages: 965-978
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Publication
First Author: Worthmann A
Year: 2024
Journal: Nat Commun
Title: Fatty acid synthesis suppresses dietary polyunsaturated fatty acid use.
Volume: 15
Issue: 1
Pages: 45
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Publication
First Author: Zhao Y
Year: 2024
Journal: Nat Commun
Title: High mobility group A1 (HMGA1) promotes the tumorigenesis of colorectal cancer by increasing lipid synthesis.
Volume: 15
Issue: 1
Pages: 9909
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Publication
First Author: Liu B
Year: 2018
Journal: Nat Commun
Title: Proteome-wide analysis of USP14 substrates revealed its role in hepatosteatosis via stabilization of FASN.
Volume: 9
Issue: 1
Pages: 4770
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Publication
First Author: Korobkina ED
Year: 2024
Journal: Nat Metab
Title: Brown fat ATP-citrate lyase links carbohydrate availability to thermogenesis and guards against metabolic stress.
Volume: 6
Issue: 11
Pages: 2187-2202
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Publication
First Author: Wei X
Year: 2016
Journal: Nature
Title: Fatty acid synthesis configures the plasma membrane for inflammation in diabetes.
Volume: 539
Issue: 7628
Pages: 294-298
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Publication
First Author: Carroll RG
Year: 2018
Journal: J Biol Chem
Title: An unexpected link between fatty acid synthase and cholesterol synthesis in proinflammatory macrophage activation.
Volume: 293
Issue: 15
Pages: 5509-5521
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Publication
First Author: Hu Y
Year: 2021
Journal: Hepatology
Title: Fatty Acid Synthase-Suppressor Screening Identifies Sorting Nexin 8 as a Therapeutic Target for NAFLD.
Volume: 74
Issue: 5
Pages: 2508-2525
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Publication
First Author: Xu G
Year: 2024
Journal: Sci Adv
Title: Mitochondrial ACSS1-K635 acetylation knock-in mice exhibit altered metabolism, cell senescence, and nonalcoholic fatty liver disease.
Volume: 10
Issue: 20
Pages: eadj5942
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Publication
First Author: Guilherme A
Year: 2023
Journal: Cell Rep
Title: Acetyl-CoA carboxylase 1 is a suppressor of the adipocyte thermogenic program.
Volume: 42
Issue: 5
Pages: 112488
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Publication  
First Author: Kelson CO
Year: 2024
Journal: Cells
Title: Upregulation of Fatty Acid Synthase Increases Activity of ?-Catenin and Expression of NOTUM to Enhance Stem-like Properties of Colorectal Cancer Cells.
Volume: 13
Issue: 19
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Publication  
First Author: Drury J
Year: 2024
Journal: Int J Mol Sci
Title: Overexpression of Fatty Acid Synthase Upregulates Glutamine-Fructose-6-Phosphate Transaminase 1 and O-Linked N-Acetylglucosamine Transferase to Increase O-GlcNAc Protein Glycosylation and Promote Colorectal Cancer Growth.
Volume: 25
Issue: 9
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Publication
First Author: Guilherme A
Year: 2017
Journal: Mol Metab
Title: Adipocyte lipid synthesis coupled to neuronal control of thermogenic programming.
Volume: 6
Issue: 8
Pages: 781-796
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Publication  
First Author: Drury J
Year: 2022
Journal: Int J Mol Sci
Title: Tissue-Specific Downregulation of Fatty Acid Synthase Suppresses Intestinal Adenoma Formation via Coordinated Reprograming of Transcriptome and Metabolism in the Mouse Model of Apc-Driven Colorectal Cancer.
Volume: 23
Issue: 12
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Publication
First Author: Singh KB
Year: 2021
Journal: Oncogene
Title: A novel metabolic function of Myc in regulation of fatty acid synthesis in prostate cancer.
Volume: 40
Issue: 3
Pages: 592-602
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Publication
First Author: Di Vizio D
Year: 2008
Journal: Cell Cycle
Title: Caveolin-1 interacts with a lipid raft-associated population of fatty acid synthase.
Volume: 7
Issue: 14
Pages: 2257-67
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Publication
First Author: Yu J
Year: 2013
Journal: J Biol Chem
Title: Modulation of fatty acid synthase degradation by concerted action of p38 MAP kinase, E3 ligase COP1, and SH2-tyrosine phosphatase Shp2.
Volume: 288
Issue: 6
Pages: 3823-30
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Publication  
First Author: Xie L
Year: 2024
Journal: Hepatol Commun
Title: Fatty acid synthesis is indispensable for Kupffer cells to eliminate bacteria in ALD progression.
Volume: 8
Issue: 9
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Publication
First Author: Bhatia B
Year: 2011
Journal: Oncogene
Title: Mitogenic Sonic hedgehog signaling drives E2F1-dependent lipogenesis in progenitor cells and medulloblastoma.
Volume: 30
Issue: 4
Pages: 410-22
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Publication  
First Author: Plataki M
Year: 2019
Journal: JCI Insight
Title: Fatty acid synthase downregulation contributes to acute lung injury in murine diet-induced obesity.
Volume: 5
Issue: 15
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Publication  
First Author: Hu J
Year: 2016
Journal: Sci Rep
Title: Co-activation of AKT and c-Met triggers rapid hepatocellular carcinoma development via the mTORC1/FASN pathway in mice.
Volume: 6
Pages: 20484
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Publication
First Author: Young KE
Year: 2017
Journal: J Leukoc Biol
Title: Fatty acid synthase regulates the pathogenicity of Th17 cells.
Volume: 102
Issue: 5
Pages: 1229-1235
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Publication
First Author: Liu Y
Year: 2020
Journal: J Clin Invest
Title: Hepatic Slug epigenetically promotes liver lipogenesis, fatty liver disease, and type 2 diabetes.
Volume: 130
Issue: 6
Pages: 2992-3004
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Publication  
First Author: Gonzalez-Bohorquez D
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: FASN-dependent de novo lipogenesis is required for brain development.
Volume: 119
Issue: 2
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Publication
First Author: Bowers M
Year: 2020
Journal: Cell Stem Cell
Title: FASN-Dependent Lipid Metabolism Links Neurogenic Stem/Progenitor Cell Activity to Learning and Memory Deficits.
Volume: 27
Issue: 1
Pages: 98-109.e11
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Publication
First Author: Li L
Year: 2016
Journal: Hepatology
Title: Differential requirement for de novo lipogenesis in cholangiocarcinoma and hepatocellular carcinoma of mice and humans.
Volume: 63
Issue: 6
Pages: 1900-13
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Publication
First Author: Di Vizio D
Year: 2007
Journal: Cancer Biol Ther
Title: Caveolin-1 is required for the upregulation of fatty acid synthase (FASN), a tumor promoter, during prostate cancer progression.
Volume: 6
Issue: 8
Pages: 1263-8
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Publication  
First Author: Duan CH
Year: 2026
Journal: Nat Commun
Title: Loss of Echs1 in neural stem and progenitor cells impairs neurogenesis via ER stress activation and lipid metabolic reprogramming.
Volume: 17
Issue: 1
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Publication
First Author: Abd Alla J
Year: 2016
Journal: J Biol Chem
Title: Inhibition of G-protein-coupled Receptor Kinase 2 Prevents the Dysfunctional Cardiac Substrate Metabolism in Fatty Acid Synthase Transgenic Mice.
Volume: 291
Issue: 6
Pages: 2583-600
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Publication
First Author: Antony N
Year: 2013
Journal: PLoS One
Title: cAMP response element binding protein1 is essential for activation of steroyl co-enzyme a desaturase 1 (Scd1) in mouse lung type II epithelial cells.
Volume: 8
Issue: 4
Pages: e59763
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Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
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Publication
First Author: Paulauskis JD
Year: 1989
Journal: Biochem Biophys Res Commun
Title: Structure of mouse fatty acid synthase mRNA. Identification of the two NADPH binding sites.
Volume: 158
Issue: 3
Pages: 690-5
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Publication
First Author: Rittner A
Year: 2018
Journal: ACS Chem Biol
Title: Characterization of the Polyspecific Transferase of Murine Type I Fatty Acid Synthase (FAS) and Implications for Polyketide Synthase (PKS) Engineering.
Volume: 13
Issue: 3
Pages: 723-732
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Publication
First Author: Rittner A
Year: 2020
Journal: Protein Sci
Title: Type I fatty acid synthase trapped in the octanoyl-bound state.
Volume: 29
Issue: 2
Pages: 589-605
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Publication
First Author: Chakravarthy MV
Year: 2009
Journal: J Lipid Res
Title: Inactivation of hypothalamic FAS protects mice from diet-induced obesity and inflammation.
Volume: 50
Issue: 4
Pages: 630-40
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Publication
First Author: Razani B
Year: 2011
Journal: J Biol Chem
Title: Fatty acid synthase modulates homeostatic responses to myocardial stress.
Volume: 286
Issue: 35
Pages: 30949-30961
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Publication
First Author: Chirala SS
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Fatty acid synthesis is essential in embryonic development: fatty acid synthase null mutants and most of the heterozygotes die in utero.
Volume: 100
Issue: 11
Pages: 6358-63
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Publication
First Author: Henriques F
Year: 2020
Journal: Cell Rep
Title: Single-Cell RNA Profiling Reveals Adipocyte to Macrophage Signaling Sufficient to Enhance Thermogenesis.
Volume: 32
Issue: 5
Pages: 107998
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Publication
First Author: Funai K
Year: 2013
Journal: J Clin Invest
Title: Muscle lipogenesis balances insulin sensitivity and strength through calcium signaling.
Volume: 123
Issue: 3
Pages: 1229-40
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Publication
First Author: Shimokawa T
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Effect of a fatty acid synthase inhibitor on food intake and expression of hypothalamic neuropeptides.
Volume: 99
Issue: 1
Pages: 66-71
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Publication
First Author: Paulauskis JD
Year: 1988
Journal: J Biol Chem
Title: Cloning and expression of mouse fatty acid synthase and other specific mRNAs. Developmental and hormonal regulation in 3T3-L1 cells.
Volume: 263
Issue: 15
Pages: 7049-54
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Publication
First Author: Semenkovich CF
Year: 1995
Journal: J Lipid Res
Title: Human fatty acid synthase mRNA: tissue distribution, genetic mapping, and kinetics of decay after glucose deprivation.
Volume: 36
Issue: 7
Pages: 1507-21
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Publication
First Author: Schmid B
Year: 2005
Journal: Biochem Biophys Res Commun
Title: Inhibition of fatty acid synthase prevents preadipocyte differentiation.
Volume: 328
Issue: 4
Pages: 1073-82
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GXD Expression      
Probe: MGI:3050126
Assay Type: RT-PCR
Annotation Date: 2004-08-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684627
Stage: TS27
Assay Id: MGI:3050144
Age: postnatal newborn
Specimen Label: +/+
Detected: true
Specimen Num: 1
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GXD Expression      
Probe: MGI:3050126
Assay Type: RT-PCR
Annotation Date: 2004-08-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684627
Stage: TS27
Assay Id: MGI:3050144
Age: postnatal newborn
Specimen Label: -/-
Detected: true
Specimen Num: 2
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GXD Expression      
Probe: MGI:5463350
Assay Type: Western blot
Annotation Date: 2013-02-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689422
Stage: TS22
Assay Id: MGI:5463364
Age: embryonic day 14.5
Specimen Label: E14.5
Detected: true
Specimen Num: 1
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GXD Expression      
Probe: MGI:5463350
Assay Type: Western blot
Annotation Date: 2013-02-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689424
Stage: TS24
Assay Id: MGI:5463364
Age: embryonic day 16.5
Specimen Label: E16.5
Detected: true
Specimen Num: 2
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GXD Expression      
Probe: MGI:5463350
Assay Type: Western blot
Annotation Date: 2013-02-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:5463364
Age: embryonic day 18.5
Specimen Label: E18.5
Detected: true
Specimen Num: 3
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