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Search results 1 to 100 out of 204 for Ghrhr

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Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Allele
Name: transgene insertion 3242, Lawrence S Kirschner
Allele Type: Transgenic
Attribute String: Recombinase
Strain
Attribute String: mutant strain, transgenic
Publication
First Author: Ariyasu D
Year: 2019
Journal: Endocrinology
Title: Decreased Activity of the Ghrhr and Gh Promoters Causes Dominantly Inherited GH Deficiency in Humanized GH1 Mouse Models.
Volume: 160
Issue: 11
Pages: 2673-2691
Publication
First Author: Yin Z
Year: 2008
Journal: Mol Endocrinol
Title: Pituitary-specific knockout of the Carney complex gene Prkar1a leads to pituitary tumorigenesis.
Volume: 22
Issue: 2
Pages: 380-7
Genotype
Symbol: Prkar1a/Prkar1a Tg(Ghrhr-cre)3242Lsk/?
Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Ghrhr-cre)3242Lsk/?
Background: involves: 129S4/SvJaeSor * FVB/N
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Chen R
Year: 2017
Journal: Oncogene
Title: mTOR promotes pituitary tumor development through activation of PTTG1.
Volume: 36
Issue: 7
Pages: 979-988
Publication
First Author: Li C
Year: 2019
Journal: Cell Death Differ
Title: mTOR-dependent upregulation of xCT blocks melanin synthesis and promotes tumorigenesis.
Volume: 26
Issue: 10
Pages: 2015-2028
Publication
First Author: Yin Z
Year: 2008
Journal: Genesis
Title: Development of a pituitary-specific cre line targeted to the Pit-1 lineage.
Volume: 46
Issue: 1
Pages: 37-42
Publication
First Author: Odle AK
Year: 2016
Journal: Endocrinology
Title: Adipocyte Versus Somatotrope Leptin: Regulation of Metabolic Functions in the Mouse.
Volume: 157
Issue: 4
Pages: 1443-56
Publication
First Author: Ikushima H
Year: 2003
Journal: J Immunol
Title: Cutting edge: Requirement for growth hormone-releasing hormone in the development of experimental autoimmune encephalomyelitis.
Volume: 171
Issue: 6
Pages: 2769-72
Publication
First Author: Godfrey P
Year: 1993
Journal: Nat Genet
Title: GHRH receptor of little mice contains a missense mutation in the extracellular domain that disrupts receptor function.
Volume: 4
Issue: 3
Pages: 227-32
Publication
First Author: Mohan S
Year: 2008
Journal: Bone
Title: A chemical mutagenesis screen to identify modifier genes that interact with growth hormone and TGF-beta signaling pathways.
Volume: 42
Issue: 2
Pages: 388-95
Publication
First Author: Toth LA
Year: 1999
Journal: Behav Genet
Title: A quantitative genetic analysis of slow-wave sleep in influenza-infected CXB recombinant inbred mice.
Volume: 29
Issue: 5
Pages: 339-48
Publication
First Author: Lehman DM
Year: 1997
Journal: Mouse Genome
Title: RAPID TYPING OF LITTLE MOUSE MUTATION
Volume: 95
Issue: 3
Pages: 689-691
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Lehman DM
Year: 1999
Journal: Brain Res Dev Brain Res
Title: Molecular, morphometric and functional analyses demonstrate that the growth hormone deficient little mouse is not hypomyelinated.
Volume: 116
Issue: 2
Pages: 191-9
Publication
First Author: Bugni JM
Year: 2001
Journal: Carcinogenesis
Title: The little mutation suppresses DEN-induced hepatocarcinogenesis in mice and abrogates genetic and hormonal modulation of susceptibility.
Volume: 22
Issue: 11
Pages: 1853-62
Publication
First Author: Christensen E
Year: 1981
Journal: Virchows Arch B Cell Pathol Incl Mol Pathol
Title: Fine structure of somatotrophs and mammotrophs in the pituitary pars distalis of the little (lit) mutant mouse.
Volume: 37
Issue: 1
Pages: 89-96
Publication
First Author: Wilson DB
Year: 1986
Journal: Histol Histopathol
Title: Growth hormone and prolactin immunoreactivity in the pituitary gland of postnatal little (lit) mice.
Volume: 1
Issue: 4
Pages: 309-13
Publication
First Author: Beamer WH
Year: 1976
Journal: J Endocrinol
Title: Stimulation of growth in the little mouse.
Volume: 71
Issue: 1
Pages: 37-45
Publication  
First Author: Eicher EM
Year: 1972
Journal: Mouse News Lett
Title: lit - little
Volume: 47
Pages: 36
Publication
First Author: Edderkaoui B
Year: 2013
Journal: Physiol Genomics
Title: ENU mutation mapped to a distal region of chromosome 11 is a major determinant of bone size.
Volume: 45
Issue: 24
Pages: 1222-8
Publication
First Author: Puche RC
Year: 2002
Journal: Growth Dev Aging
Title: Growth and development of male "little" mice assessed with Parks' theory of feeding and growth.
Volume: 66
Issue: 2
Pages: 71-8
Publication      
First Author: Donahue LR
Year: 2014
Journal: MGI Direct Data Submission
Title: Characterization data for C3.B6-Ghrhrlit/J
Publication
First Author: Sharma Y
Year: 2005
Journal: Exp Hematol
Title: Mice severely deficient in growth hormone have normal hematopoiesis.
Volume: 33
Issue: 7
Pages: 776-83
Publication
First Author: Majeed N
Year: 2005
Journal: Oncogene
Title: A germ line mutation that delays prostate cancer progression and prolongs survival in a murine prostate cancer model.
Volume: 24
Issue: 29
Pages: 4736-40
Publication
First Author: Obal F Jr
Year: 2003
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Sleep in mice with nonfunctional growth hormone-releasing hormone receptors.
Volume: 284
Issue: 1
Pages: R131-9
Publication
First Author: Boughner JC
Year: 2008
Journal: J Anat
Title: Short-faced mice and developmental interactions between the brain and the face.
Volume: 213
Issue: 6
Pages: 646-62
Publication
First Author: Tyler AL
Year: 2016
Journal: PLoS Genet
Title: Weak Epistasis Generally Stabilizes Phenotypes in a Mouse Intercross.
Volume: 12
Issue: 2
Pages: e1005805
Publication
First Author: Jansson JO
Year: 1986
Journal: Science
Title: Receptor-associated resistance to growth hormone-releasing factor in dwarf "little" mice.
Volume: 232
Issue: 4749
Pages: 511-2
Publication
First Author: Johnson D
Year: 1995
Journal: J Mol Endocrinol
Title: Sexual dimorphism and growth hormone induction of murine pheromone-binding proteins.
Volume: 14
Issue: 1
Pages: 21-34
Publication
First Author: Schneider P
Year: 2007
Journal: J Bone Miner Res
Title: Ultrastructural properties in cortical bone vary greatly in two inbred strains of mice as assessed by synchrotron light based micro- and nano-CT.
Volume: 22
Issue: 10
Pages: 1557-70
Publication
First Author: Itoh E
Year: 2004
Journal: Endocr J
Title: Diurnal variation in growth hormone receptor messenger ribonucleic acid in liver and skeletal muscle of lit/+ and lit/lit mice.
Volume: 51
Issue: 6
Pages: 529-35
Publication
First Author: Wilson DB
Year: 1992
Journal: Histol Histopathol
Title: Histopathology of the pituitary gland in neonatal little (lit) mutant mice.
Volume: 7
Issue: 3
Pages: 451-5
Publication
First Author: Fang S
Year: 2000
Journal: Endocrinology
Title: Development of a transgenic mouse that overexpresses a novel product of the growth hormone-releasing hormone gene.
Volume: 141
Issue: 4
Pages: 1377-83
Publication
First Author: Wajnrajch MP
Year: 1996
Journal: Nat Genet
Title: Nonsense mutation in the human growth hormone-releasing hormone receptor causes growth failure analogous to the little (lit) mouse.
Volume: 12
Issue: 1
Pages: 88-90
Publication
First Author: Cao Y
Year: 1995
Journal: Pediatr Res
Title: Isolated growth hormone deficiency: testing the little mouse hypothesis in man and exclusion of mutations within the extracellular domain of the growth hormone-releasing hormone receptor.
Volume: 38
Issue: 6
Pages: 962-6
GXD Expression      
Probe: MGI:5300030
Assay Type: RT-PCR
Annotation Date: 2011-12-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3599825
Stage: TS25
Assay Id: MGI:5300055
Age: embryonic day 17.5
Specimen Label: LSD1 wt
Detected: true
Specimen Num: 1
GXD Expression        
Probe: MGI:5300030
Assay Type: RT-PCR
Annotation Date: 2011-12-28
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:3599825
Stage: TS25
Assay Id: MGI:5300055
Age: embryonic day 17.5
Specimen Label: LSD1 KO
Specimen Num: 2
GXD Expression    
Probe: MGI:5642372
Assay Type: Northern blot
Annotation Date: 2015-07-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3599828
Stage: TS28
Assay Id: MGI:5642373
Age: postnatal
Image: 2
Specimen Label: Pituitary
Detected: true
Specimen Num: 2
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1777828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693072
Age: postnatal adult
Image: JAX_1797038
Specimen Label: JAX_1797038
Detected: true
Specimen Num: 3
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1737328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693072
Age: postnatal adult
Image: JAX_1797035
Note: kidney
Specimen Label: JAX_1797035
Detected: true
Specimen Num: 14
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3267828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693072
Age: postnatal adult
Image: JAX_1797042
Specimen Label: JAX_1797042
Detected: true
Specimen Num: 7
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1697428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693072
Age: postnatal adult
Image: JAX_1797037
Specimen Label: JAX_1797037
Detected: true
Specimen Num: 2
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1925228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693072
Age: postnatal adult
Image: JAX_1797046
Specimen Label: JAX_1797046
Detected: true
Specimen Num: 11
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1753628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693072
Age: postnatal adult
Image: JAX_1797039
Specimen Label: JAX_1797039
Detected: true
Specimen Num: 4
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1778728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693072
Age: postnatal adult
Image: JAX_1797040
Specimen Label: JAX_1797040
Detected: true
Specimen Num: 5
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1754428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693072
Age: postnatal adult
Image: JAX_1797041
Specimen Label: JAX_1797041
Detected: true
Specimen Num: 6
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3283428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693072
Age: postnatal adult
Image: JAX_1797043
Specimen Label: JAX_1797043
Detected: true
Specimen Num: 8
GXD Expression
Probe: MGI:5642331
Assay Type: RNA in situ
Annotation Date: 2015-07-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1751424
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:5642332
Age: embryonic day 16.5
Image: 2c
Note: Expression is in the central, caudal portion.
Specimen Label: 2c
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:5642331
Assay Type: RNA in situ
Annotation Date: 2015-07-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1751424
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:5642332
Age: embryonic day 16.5
Image: 4b wt e16.5
Note: Expression is in the central, caudal portion.
Specimen Label: 4b wt e16.5
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5642331
Assay Type: RNA in situ
Annotation Date: 2015-07-02
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1751424
Stage: TS24
Assay Id: MGI:5642332
Age: embryonic day 16.5
Image: 4b dw e16.5
Specimen Label: 4b dw e16.5
Detected: false
Specimen Num: 3
GXD Expression
Probe: MGI:5642331
Assay Type: RNA in situ
Annotation Date: 2015-07-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1751426
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:5642332
Age: embryonic day 18.5
Image: 4b wt e18.5
Note: Expression is in the central, caudal portion.
Specimen Label: 4b wt e18.5
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:5642331
Assay Type: RNA in situ
Annotation Date: 2015-07-02
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1751426
Stage: TS26
Assay Id: MGI:5642332
Age: embryonic day 18.5
Image: 4b dw e18.5
Specimen Label: 4b dw e18.5
Detected: false
Specimen Num: 5
GXD Expression      
Probe: MGI:5642331
Assay Type: RNA in situ
Annotation Date: 2015-07-02
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1751423
Stage: TS23
Assay Id: MGI:5642332
Age: embryonic day 15.5
Specimen Label: not shown wt e15.5
Detected: false
Specimen Num: 6
GXD Expression      
Probe: MGI:5642331
Assay Type: RNA in situ
Annotation Date: 2015-07-02
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1751423
Stage: TS23
Assay Id: MGI:5642332
Age: embryonic day 15.5
Specimen Label: not shown dw e15.5
Detected: false
Specimen Num: 7
GXD Expression  
Probe: MGI:5642331
Assay Type: RNA in situ
Annotation Date: 2015-07-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1751425
Pattern: Regionally restricted
Stage: TS25
Assay Id: MGI:5642332
Age: embryonic day 17.5
Note: Expression is in the central, caudal portion.
Specimen Label: not shown wt e17.5
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:5642331
Assay Type: RNA in situ
Annotation Date: 2015-07-02
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1751425
Stage: TS25
Assay Id: MGI:5642332
Age: embryonic day 17.5
Specimen Label: not shown dw e17.5
Detected: false
Specimen Num: 9
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1754028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693072
Age: postnatal adult
Image: JAX_1797036
Specimen Label: JAX_1797036
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:5300195
Assay Type: RNA in situ
Annotation Date: 2011-12-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3599825
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:5300194
Age: embryonic day 17.5
Image: 2a left
Note: Expressed in somatotropic cells.
Specimen Label: 2a left
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5300195
Assay Type: RNA in situ
Annotation Date: 2011-12-29
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3599825
Stage: TS25
Assay Id: MGI:5300194
Age: embryonic day 17.5
Image: 2a right
Specimen Label: 2a right
Detected: false
Specimen Num: 2
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3599828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693072
Age: postnatal adult
Image: JAX_1797044
Specimen Label: JAX_1797044
Detected: true
Specimen Num: 9
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1757728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693072
Age: postnatal adult
Image: JAX_1797045
Specimen Label: JAX_1797045
Detected: true
Specimen Num: 10
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693072
Age: postnatal adult
Image: JAX_1797047
Specimen Label: JAX_1797047
Detected: true
Specimen Num: 12
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1881228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693072
Age: postnatal adult
Image: JAX_1797034
Specimen Label: JAX_1797034
Detected: true
Specimen Num: 13
Publication
First Author: Flurkey K
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: Lifespan extension and delayed immune and collagen aging in mutant mice with defects in growth hormone production.
Volume: 98
Issue: 12
Pages: 6736-41
Publication
First Author: Pati D
Year: 2002
Journal: Mol Cell Biol
Title: Linking sister chromatid cohesion and apoptosis: role of Rad21.
Volume: 22
Issue: 23
Pages: 8267-77
Publication
First Author: Ishimori N
Year: 2006
Journal: J Bone Miner Res
Title: Quantitative trait loci that determine BMD in C57BL/6J and 129S1/SvImJ inbred mice.
Volume: 21
Issue: 1
Pages: 105-12
Publication
First Author: Murao S
Year: 1995
Journal: Res Commun Mol Pathol Pharmacol
Title: Gene expression of hypothalamic growth hormone (GH)-releasing hormone and somatostatin does not correlate with pulsatile secretion of GH in the adult mouse.
Volume: 89
Issue: 3
Pages: 269-77
Publication
First Author: Frohman MA
Year: 1989
Journal: Mol Endocrinol
Title: Cloning and characterization of mouse growth hormone-releasing hormone (GRH) complementary DNA: increased GRH messenger RNA levels in the growth hormone-deficient lit/lit mouse.
Volume: 3
Issue: 10
Pages: 1529-36
Publication
First Author: del Rincon JP
Year: 2007
Journal: Diabetes
Title: Growth hormone regulation of p85alpha expression and phosphoinositide 3-kinase activity in adipose tissue: mechanism for growth hormone-mediated insulin resistance.
Volume: 56
Issue: 6
Pages: 1638-46
Publication
First Author: Menagh PJ
Year: 2010
Journal: J Bone Miner Res
Title: Growth hormone regulates the balance between bone formation and bone marrow adiposity.
Volume: 25
Issue: 4
Pages: 757-68
Publication
First Author: Wong JH
Year: 2008
Journal: J Clin Invest
Title: Sex differences in thrombosis in mice are mediated by sex-specific growth hormone secretion patterns.
Volume: 118
Issue: 8
Pages: 2969-78
Publication
First Author: Fleenor D
Year: 2005
Journal: Endocrinology
Title: Roles of the lactogens and somatogens in perinatal and postnatal metabolism and growth: studies of a novel mouse model combining lactogen resistance and growth hormone deficiency.
Volume: 146
Issue: 1
Pages: 103-12
Publication
First Author: Iida K
Year: 2004
Journal: Am J Physiol Endocrinol Metab
Title: Regulation of full-length and truncated growth hormone (GH) receptor by GH in tissues of lit/lit or bovine GH transgenic mice.
Volume: 287
Issue: 3
Pages: E566-73
Publication
First Author: B√ľnger L
Year: 1999
Journal: Genet Res
Title: Role of growth hormone in the genetic change of mice divergently selected for body weight and fatness.
Volume: 74
Issue: 3
Pages: 351-60
Publication
First Author: Richards RG
Year: 2004
Journal: Endocrinology
Title: Mammary gland branching morphogenesis is diminished in mice with a deficiency of insulin-like growth factor-I (IGF-I), but not in mice with a liver-specific deletion of IGF-I.
Volume: 145
Issue: 7
Pages: 3106-10
Publication
First Author: Sos BC
Year: 2011
Journal: J Clin Invest
Title: Abrogation of growth hormone secretion rescues fatty liver in mice with hepatocyte-specific deletion of JAK2.
Volume: 121
Issue: 4
Pages: 1412-23