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Search results 1 to 91 out of 91 for Gpr179

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Hits by Category

Hits by Strain

Type Details Score
Gene
440435 | GPR179
Type: gene
Organism: human
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Gene
100496332 | gpr179
Type: gene
Organism: frog, western clawed
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Gene
107055290 | GPR179
Type: gene
Organism: chicken
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Gene
287657 | Gpr179
Type: gene
Organism: rat
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Gene
491040 | GPR179
Type: gene
Organism: dog, domestic
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Gene
454609 | GPR179
Type: gene
Organism: chimpanzee
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Gene
787335 | GPR179
Type: gene
Organism: cattle
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Gene
100537469 | gpr179
Type: gene
Organism: zebrafish
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Gene
693410 | GPR179
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:2443409 | Gpr179
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR032964 | GPR179
Type: Family
Description: GPR179 is a probable G-protein coupled receptor that plays a critical role in DBC (depolarising bipolar cell) signal transduction []. Mutations in the GPR179 gene cause autosomal recessive complete congenital stationary night blindness (CSNB), which is characterised by an ON-bipolar retinal cell dysfunction [].
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Publication
22325362 | J:185567
First Author: Peachey NS
Year: 2012
Journal: Am J Hum Genet
Title: GPR179 is required for depolarizing bipolar cell function and is mutated in autosomal-recessive complete congenital stationary night blindness.
Volume: 90
Issue: 2
Pages: 331-9
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Publication
36613663 | J:340157
 
First Author: Wilmet B
Year: 2022
Journal: Int J Mol Sci
Title: Mice Lacking Gpr179 with Complete Congenital Stationary Night Blindness Are a Good Model for Myopia.
Volume: 24
Issue: 1
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Publication
24114537 | J:214871
First Author: Orlandi C
Year: 2013
Journal: Invest Ophthalmol Vis Sci
Title: Orphan receptor GPR179 forms macromolecular complexes with components of metabotropic signaling cascade in retina ON-bipolar neurons.
Volume: 54
Issue: 10
Pages: 7153-61
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Publication
24790204 | J:211063
First Author: Ray TA
Year: 2014
Journal: J Neurosci
Title: GPR179 is required for high sensitivity of the mGluR6 signaling cascade in depolarizing bipolar cells.
Volume: 34
Issue: 18
Pages: 6334-43
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Publication
24084093 | J:214877
First Author: Klooster J
Year: 2013
Journal: Invest Ophthalmol Vis Sci
Title: Ultrastructural localization of GPR179 and the impact of mutant forms on retinal function in CSNB1 patients and a mouse model.
Volume: 54
Issue: 10
Pages: 6973-81
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Publication
24222301 | -
First Author: Orhan E
Year: 2013
Journal: Invest Ophthalmol Vis Sci
Title: Further insights into GPR179: expression, localization, and associated pathogenic mechanisms leading to complete congenital stationary night blindness.
Volume: 54
Issue: 13
Pages: 8041-50
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Publication
30282023 | J:269858
First Author: Orlandi C
Year: 2018
Journal: Cell Rep
Title: Transsynaptic Binding of Orphan Receptor GPR179 to Dystroglycan-Pikachurin Complex Is Essential for the Synaptic Organization of Photoreceptors.
Volume: 25
Issue: 1
Pages: 130-145.e5
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Protein
Q8BFV4
Organism: Mus musculus/domesticus
Length: 333  
Fragment?: false
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Protein
E9PY61
Organism: Mus musculus/domesticus
Length: 2293  
Fragment?: false
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Publication
33922602 | J:308356
 
First Author: Orhan E
Year: 2021
Journal: Int J Mol Sci
Title: A New Mouse Model for Complete Congenital Stationary Night Blindness Due to Gpr179 Deficiency.
Volume: 22
Issue: 9
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Publication
22689652 | J:185272
First Author: Orlandi C
Year: 2012
Journal: J Cell Biol
Title: GPR158/179 regulate G protein signaling by controlling localization and activity of the RGS7 complexes.
Volume: 197
Issue: 6
Pages: 711-9
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Publication
16229975 | J:103455
 
First Author: Bjarnadóttir TK
Year: 2005
Journal: Gene
Title: The gene repertoire and the common evolutionary history of glutamate, pheromone (V2R), taste(1) and other related G protein-coupled receptors.
Volume: 362
Pages: 70-84
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Publication
26396487 | J:224435
 
First Author: Chang B
Year: 2015
Journal: Mol Vis
Title: Survey of the nob5 mutation in C3H substrains.
Volume: 21
Pages: 1101-5
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Publication
24415894 | J:211946
 
First Author: Balmer J
Year: 2013
Journal: Mol Vis
Title: Presence of the Gpr179(nob5) allele in a C3H-derived transgenic mouse.
Volume: 19
Pages: 2615-25
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Publication
25613321 | J:219703
 
First Author: Nishiguchi KM
Year: 2015
Journal: Nat Commun
Title: Gene therapy restores vision in rd1 mice after removal of a confounding mutation in Gpr179.
Volume: 6
Pages: 6006
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Publication
26961947 | J:231666
First Author: Sarria I
Year: 2016
Journal: J Neurosci
Title: Intermolecular Interaction between Anchoring Subunits Specify Subcellular Targeting and Function of RGS Proteins in Retina ON-Bipolar Neurons.
Volume: 36
Issue: 10
Pages: 2915-25
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Protein Coding Gene
MGP_CAROLIEiJ_G0017053 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0019029 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0018997 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0018967 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0018970 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0018784 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2443409 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0019422 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0018337 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0018755 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0018863 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0018852 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0018933 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0018879 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0019462 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0018109 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0018387 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0018182 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0017899 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
   
Probe: MGI:6148994
Assay Type: RNA in situ
Annotation Date: 2018-04-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3277028
Stage: TS28
Assay Id: MGI:6149144
Age: postnatal day 10
Image: 2C
Specimen Label: 2C
Detected: false
Specimen Num: 1
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Publication
22865473 | J:285856
First Author: Peachey NS
Year: 2012
Journal: Doc Ophthalmol
Title: Response properties of slow PIII in the Large (vls) mutant.
Volume: 125
Issue: 3
Pages: 203-9
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Publication
31959619 | J:288415
 
First Author: Hasan N
Year: 2020
Journal: eNeuro
Title: LRIT3 is Required for Nyctalopin Expression and Normal ON and OFF Pathway Signaling in the Retina.
Volume: 7
Issue: 1
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Publication
22896717 | J:209941
First Author: Peachey NS
Year: 2012
Journal: J Neurophysiol
Title: Depolarizing bipolar cell dysfunction due to a Trpm1 point mutation.
Volume: 108
Issue: 9
Pages: 2442-51
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Publication
25997951 | J:242812
First Author: Neuillé M
Year: 2015
Journal: Eur J Neurosci
Title: LRIT3 is essential to localize TRPM1 to the dendritic tips of depolarizing bipolar cells and may play a role in cone synapse formation.
Volume: 42
Issue: 3
Pages: 1966-75
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Publication
28262416 | J:256152
First Author: Wang Y
Year: 2017
Journal: Neuron
Title: The Auxiliary Calcium Channel Subunit α2δ4 Is Required for Axonal Elaboration, Synaptic Transmission, and Wiring of Rod Photoreceptors.
Volume: 93
Issue: 6
Pages: 1359-1374.e6
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Publication
36179691 | J:332184
First Author: Cao Y
Year: 2022
Journal: Curr Biol
Title: Post-developmental plasticity of the primary rod pathway allows restoration of visually guided behaviors.
Volume: 32
Issue: 22
Pages: 4783-4796.e3
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Publication
28851741 | J:246056
First Author: Khrimian L
Year: 2017
Journal: J Exp Med
Title: Gpr158 mediates osteocalcin's regulation of cognition.
Volume: 214
Issue: 10
Pages: 2859-2873
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Publication
35681537 | J:325724
 
First Author: Gong Y
Year: 2022
Journal: Cells
Title: Peroxisome Metabolism Contributes to PIEZO2-Mediated Mechanical Allodynia.
Volume: 11
Issue: 11
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Publication
- | J:147112
     
First Author: Taconic
Year: 2006
Journal: MGI Direct Data Submission
Title: Information obtained from Taconic website.
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Publication
- | J:157064
     
First Author: University of California, Davis
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the University of California, Davis
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
22325361 | J:196741
First Author: Audo I
Year: 2012
Journal: Am J Hum Genet
Title: Whole-exome sequencing identifies mutations in GPR179 leading to autosomal-recessive complete congenital stationary night blindness.
Volume: 90
Issue: 2
Pages: 321-30
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Allele
Gpr179<nob5> | MGI:5431477
 
Name: G protein-coupled receptor 179; no b wave 5
Allele Type: Spontaneous
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Genotype
Genotype
Symbol: Gpr179/Gpr179
Background: involves: C3H
Zygosity: hm
Has Mutant Allele: true
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DO Term
DOID:0110869 | congenital stationary night blindness 1E
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Protein
Q8C3D0
Organism: Mus musculus/domesticus
Length: 474  
Fragment?: false
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Publication
23451275 | -
First Author: Patel N
Year: 2013
Journal: PLoS One
Title: GPR158, an orphan member of G protein-coupled receptor Family C: glucocorticoid-stimulated expression and novel nuclear role.
Volume: 8
Issue: 2
Pages: e57843
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Publication
30855200 | J:280560
First Author: Itakura T
Year: 2019
Journal: J Ocul Pharmacol Ther
Title: GPR158 in the Visual System: Homeostatic Role in Regulation of Intraocular Pressure.
Volume: 35
Issue: 4
Pages: 203-215
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Publication
25693195 | J:238883
First Author: Patel N
Year: 2015
Journal: PLoS One
Title: Expression and functional role of orphan receptor GPR158 in prostate cancer growth and progression.
Volume: 10
Issue: 2
Pages: e0117758
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Publication
29419376 | J:263624
   
First Author: Sutton LP
Year: 2018
Journal: Elife
Title: Orphan receptor GPR158 controls stress-induced depression.
Volume: 7
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Protein Domain
IPR043458 | GPR158/179
Type: Family
Description: This group includes orphan receptors GPR158, GPR158-like (also called GPR179) and similar proteins. These orphan receptors are closely related to the type B receptor for gamma-aminobutyric acid (GABA-B), which is activated by its endogenous ligand GABA, the principal inhibitory neurotransmitter []. Both GPR179 and GPR158 were shown to recruit regulator of G protein signaling (RGS) complexes and thus regulate activity of other GPCRs []. GPR158 has been suggested to act as a homeostatic regulator of intraocular pressure and could be a pharmacological target for managing ocular hypertension [, ]. It has been linked to prostate cancer growth and progression []. It also serves as a novel regulator operating in the prefrontal cortex (PFC) that links chronic stress to depression []. GPR179 has been shown to play a critical role in depolarizing bipolar cell signal transduction. It is mutated in autosomal-recessive complete congenital stationary night blindness [].
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Publication
29023785 | J:269906
First Author: Hunter DD
Year: 2019
Journal: J Comp Neurol
Title: CNS synapses are stabilized trans-synaptically by laminins and laminin-interacting proteins.
Volume: 527
Issue: 1
Pages: 67-86
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Protein
Q8C419
Organism: Mus musculus/domesticus
Length: 1200  
Fragment?: false
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Protein
Q8BSU1
Organism: Mus musculus/domesticus
Length: 631  
Fragment?: false
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Publication
38408870 | J:360947
 
First Author: Hasan N
Year: 2024
Journal: eNeuro
Title: Cone Synaptic function is modulated by the leucine rich repeat (LRR) adhesion molecule LRFN2.
Volume: 11
Issue: 3
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