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Search results 1 to 90 out of 90 for Gpr179

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Categories

Hits by Strain

Hits by Category

Type Details Score
Gene
440435 | GPR179
Type: gene
Organism: human
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Gene
100537469 | gpr179
Type: gene
Organism: zebrafish
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Gene
693410 | GPR179
Type: gene
Organism: macaque, rhesus
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Gene
100496332 | gpr179
Type: gene
Organism: frog, western clawed
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Gene
107055290 | GPR179
Type: gene
Organism: chicken
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Gene
287657 | Gpr179
Type: gene
Organism: rat
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Gene
491040 | GPR179
Type: gene
Organism: dog, domestic
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Gene
454609 | GPR179
Type: gene
Organism: chimpanzee
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Gene
787335 | GPR179
Type: gene
Organism: cattle
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Protein Coding Gene
MGI:2443409 | Gpr179
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR032964 | GPR179
Type: Family
Description: GPR179 is a probable G-protein coupled receptor that plays a critical role in DBC (depolarising bipolar cell) signal transduction []. Mutations in the GPR179 gene cause autosomal recessive complete congenital stationary night blindness (CSNB), which is characterised by an ON-bipolar retinal cell dysfunction [].
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Publication
22325362 | J:185567
First Author: Peachey NS
Year: 2012
Journal: Am J Hum Genet
Title: GPR179 is required for depolarizing bipolar cell function and is mutated in autosomal-recessive complete congenital stationary night blindness.
Volume: 90
Issue: 2
Pages: 331-9
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Publication
36613663 | J:340157
 
First Author: Wilmet B
Year: 2022
Journal: Int J Mol Sci
Title: Mice Lacking Gpr179 with Complete Congenital Stationary Night Blindness Are a Good Model for Myopia.
Volume: 24
Issue: 1
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Publication
24114537 | J:214871
First Author: Orlandi C
Year: 2013
Journal: Invest Ophthalmol Vis Sci
Title: Orphan receptor GPR179 forms macromolecular complexes with components of metabotropic signaling cascade in retina ON-bipolar neurons.
Volume: 54
Issue: 10
Pages: 7153-61
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Publication
24790204 | J:211063
First Author: Ray TA
Year: 2014
Journal: J Neurosci
Title: GPR179 is required for high sensitivity of the mGluR6 signaling cascade in depolarizing bipolar cells.
Volume: 34
Issue: 18
Pages: 6334-43
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Publication
24084093 | J:214877
First Author: Klooster J
Year: 2013
Journal: Invest Ophthalmol Vis Sci
Title: Ultrastructural localization of GPR179 and the impact of mutant forms on retinal function in CSNB1 patients and a mouse model.
Volume: 54
Issue: 10
Pages: 6973-81
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Publication
24222301 | -
First Author: Orhan E
Year: 2013
Journal: Invest Ophthalmol Vis Sci
Title: Further insights into GPR179: expression, localization, and associated pathogenic mechanisms leading to complete congenital stationary night blindness.
Volume: 54
Issue: 13
Pages: 8041-50
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Publication
30282023 | J:269858
First Author: Orlandi C
Year: 2018
Journal: Cell Rep
Title: Transsynaptic Binding of Orphan Receptor GPR179 to Dystroglycan-Pikachurin Complex Is Essential for the Synaptic Organization of Photoreceptors.
Volume: 25
Issue: 1
Pages: 130-145.e5
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Protein
Q8BFV4
Organism: Mus musculus/domesticus
Length: 333  
Fragment?: false
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Protein
E9PY61
Organism: Mus musculus/domesticus
Length: 2293  
Fragment?: false
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Publication
33922602 | J:308356
 
First Author: Orhan E
Year: 2021
Journal: Int J Mol Sci
Title: A New Mouse Model for Complete Congenital Stationary Night Blindness Due to Gpr179 Deficiency.
Volume: 22
Issue: 9
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Publication
22689652 | J:185272
First Author: Orlandi C
Year: 2012
Journal: J Cell Biol
Title: GPR158/179 regulate G protein signaling by controlling localization and activity of the RGS7 complexes.
Volume: 197
Issue: 6
Pages: 711-9
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Publication
16229975 | J:103455
 
First Author: Bjarnadóttir TK
Year: 2005
Journal: Gene
Title: The gene repertoire and the common evolutionary history of glutamate, pheromone (V2R), taste(1) and other related G protein-coupled receptors.
Volume: 362
Pages: 70-84
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Publication
26396487 | J:224435
 
First Author: Chang B
Year: 2015
Journal: Mol Vis
Title: Survey of the nob5 mutation in C3H substrains.
Volume: 21
Pages: 1101-5
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Publication
24415894 | J:211946
 
First Author: Balmer J
Year: 2013
Journal: Mol Vis
Title: Presence of the Gpr179(nob5) allele in a C3H-derived transgenic mouse.
Volume: 19
Pages: 2615-25
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Publication
25613321 | J:219703
 
First Author: Nishiguchi KM
Year: 2015
Journal: Nat Commun
Title: Gene therapy restores vision in rd1 mice after removal of a confounding mutation in Gpr179.
Volume: 6
Pages: 6006
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Publication
26961947 | J:231666
First Author: Sarria I
Year: 2016
Journal: J Neurosci
Title: Intermolecular Interaction between Anchoring Subunits Specify Subcellular Targeting and Function of RGS Proteins in Retina ON-Bipolar Neurons.
Volume: 36
Issue: 10
Pages: 2915-25
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Protein Coding Gene
MGP_CAROLIEiJ_G0017053 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0019029 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0018997 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0018967 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0018970 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0018784 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2443409 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0019422 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0018337 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0018755 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0018863 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0018852 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0018933 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0018879 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0019462 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0018109 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0018387 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0018182 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0017899 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
   
Probe: MGI:6148994
Assay Type: RNA in situ
Annotation Date: 2018-04-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3277028
Stage: TS28
Assay Id: MGI:6149144
Age: postnatal day 10
Image: 2C
Specimen Label: 2C
Detected: false
Specimen Num: 1
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Publication
22865473 | J:285856
First Author: Peachey NS
Year: 2012
Journal: Doc Ophthalmol
Title: Response properties of slow PIII in the Large (vls) mutant.
Volume: 125
Issue: 3
Pages: 203-9
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Publication
31959619 | J:288415
 
First Author: Hasan N
Year: 2020
Journal: eNeuro
Title: LRIT3 is Required for Nyctalopin Expression and Normal ON and OFF Pathway Signaling in the Retina.
Volume: 7
Issue: 1
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Publication
22896717 | J:209941
First Author: Peachey NS
Year: 2012
Journal: J Neurophysiol
Title: Depolarizing bipolar cell dysfunction due to a Trpm1 point mutation.
Volume: 108
Issue: 9
Pages: 2442-51
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Publication
25997951 | J:242812
First Author: Neuillé M
Year: 2015
Journal: Eur J Neurosci
Title: LRIT3 is essential to localize TRPM1 to the dendritic tips of depolarizing bipolar cells and may play a role in cone synapse formation.
Volume: 42
Issue: 3
Pages: 1966-75
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Publication
28262416 | J:256152
First Author: Wang Y
Year: 2017
Journal: Neuron
Title: The Auxiliary Calcium Channel Subunit α2δ4 Is Required for Axonal Elaboration, Synaptic Transmission, and Wiring of Rod Photoreceptors.
Volume: 93
Issue: 6
Pages: 1359-1374.e6
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Publication
36179691 | J:332184
First Author: Cao Y
Year: 2022
Journal: Curr Biol
Title: Post-developmental plasticity of the primary rod pathway allows restoration of visually guided behaviors.
Volume: 32
Issue: 22
Pages: 4783-4796.e3
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Publication
28851741 | J:246056
First Author: Khrimian L
Year: 2017
Journal: J Exp Med
Title: Gpr158 mediates osteocalcin's regulation of cognition.
Volume: 214
Issue: 10
Pages: 2859-2873
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Publication
35681537 | J:325724
 
First Author: Gong Y
Year: 2022
Journal: Cells
Title: Peroxisome Metabolism Contributes to PIEZO2-Mediated Mechanical Allodynia.
Volume: 11
Issue: 11
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Publication
- | J:147112
     
First Author: Taconic
Year: 2006
Journal: MGI Direct Data Submission
Title: Information obtained from Taconic website.
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Publication
- | J:157064
     
First Author: University of California, Davis
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the University of California, Davis
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
22325361 | J:196741
First Author: Audo I
Year: 2012
Journal: Am J Hum Genet
Title: Whole-exome sequencing identifies mutations in GPR179 leading to autosomal-recessive complete congenital stationary night blindness.
Volume: 90
Issue: 2
Pages: 321-30
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Allele
Gpr179<nob5> | MGI:5431477
 
Name: G protein-coupled receptor 179; no b wave 5
Allele Type: Spontaneous
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Genotype
Genotype
Symbol: Gpr179/Gpr179
Background: involves: C3H
Zygosity: hm
Has Mutant Allele: true
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DO Term
DOID:0110869 | congenital stationary night blindness 1E
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Protein
Q8C3D0
Organism: Mus musculus/domesticus
Length: 474  
Fragment?: false
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Publication
23451275 | -
First Author: Patel N
Year: 2013
Journal: PLoS One
Title: GPR158, an orphan member of G protein-coupled receptor Family C: glucocorticoid-stimulated expression and novel nuclear role.
Volume: 8
Issue: 2
Pages: e57843
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Publication
30855200 | J:280560
First Author: Itakura T
Year: 2019
Journal: J Ocul Pharmacol Ther
Title: GPR158 in the Visual System: Homeostatic Role in Regulation of Intraocular Pressure.
Volume: 35
Issue: 4
Pages: 203-215
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Publication
25693195 | J:238883
First Author: Patel N
Year: 2015
Journal: PLoS One
Title: Expression and functional role of orphan receptor GPR158 in prostate cancer growth and progression.
Volume: 10
Issue: 2
Pages: e0117758
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Publication
29419376 | J:263624
   
First Author: Sutton LP
Year: 2018
Journal: Elife
Title: Orphan receptor GPR158 controls stress-induced depression.
Volume: 7
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Protein Domain
IPR043458 | GPR158/179
Type: Family
Description: This group includes orphan receptors GPR158, GPR158-like (also called GPR179) and similar proteins. These orphan receptors are closely related to the type B receptor for gamma-aminobutyric acid (GABA-B), which is activated by its endogenous ligand GABA, the principal inhibitory neurotransmitter []. Both GPR179 and GPR158 were shown to recruit regulator of G protein signaling (RGS) complexes and thus regulate activity of other GPCRs []. GPR158 has been suggested to act as a homeostatic regulator of intraocular pressure and could be a pharmacological target for managing ocular hypertension [, ]. It has been linked to prostate cancer growth and progression []. It also serves as a novel regulator operating in the prefrontal cortex (PFC) that links chronic stress to depression []. GPR179 has been shown to play a critical role in depolarizing bipolar cell signal transduction. It is mutated in autosomal-recessive complete congenital stationary night blindness [].
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Publication
29023785 | J:269906
First Author: Hunter DD
Year: 2019
Journal: J Comp Neurol
Title: CNS synapses are stabilized trans-synaptically by laminins and laminin-interacting proteins.
Volume: 527
Issue: 1
Pages: 67-86
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Protein
Q8C419
Organism: Mus musculus/domesticus
Length: 1200  
Fragment?: false
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Protein
Q8BSU1
Organism: Mus musculus/domesticus
Length: 631  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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