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Search results 1 to 100 out of 220 for Gpr55

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0.041s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Domain
Type: Family
Description: Several 7TM receptors have been cloned but theirendogenous ligands are unknown; these have been termed orphan receptors. However, recent research has identified certain pharmacological targets that could be investigated to find, for example, new potential cannabinoid receptors or channels [, , ]. GPR18 [, ], GPR55 [, ], GPR119 []show little structural similarity to CB1 and CB2 receptors, but they respond to endogenous agents analogous to the endogenous cannabinoid ligands, as well as some natural/synthetic cannabinoid receptor ligands []. However, because they do not fulfill all of the cannabinoid receptor criteria defined by IUPHAR, the classification of these proteins remains a contentious issue due to conflicting pharmacological results. As a result, they remain classified as putative endogenous agonists by IUPHAR [].This entry represents G protein-coupled receptor 55. It is thought to play a role in bone physiology by regulating osteoclast number and function [].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Whyte LS
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: The putative cannabinoid receptor GPR55 affects osteoclast function in vitro and bone mass in vivo.
Volume: 106
Issue: 38
Pages: 16511-6
Publication
First Author: Carey LM
Year: 2017
Journal: Sci Rep
Title: Inflammatory and Neuropathic Nociception is Preserved in GPR55 Knockout Mice.
Volume: 7
Issue: 1
Pages: 944
Publication  
First Author: Cherif H
Year: 2015
Journal: eNeuro
Title: Role of GPR55 during Axon Growth and Target Innervation.
Volume: 2
Issue: 5
Publication  
First Author: Korchynska S
Year: 2019
Journal: JCI Insight
Title: GPR55 controls functional differentiation of self-renewing epithelial progenitors for salivation.
Volume: 4
Issue: 4
Publication
First Author: Ryberg E
Year: 2007
Journal: Br J Pharmacol
Title: The orphan receptor GPR55 is a novel cannabinoid receptor.
Volume: 152
Issue: 7
Pages: 1092-101
Publication
First Author: Pietr M
Year: 2009
Journal: FEBS Lett
Title: Differential changes in GPR55 during microglial cell activation.
Volume: 583
Issue: 12
Pages: 2071-6
Publication
First Author: Hill JD
Year: 2018
Journal: Br J Pharmacol
Title: Activation of GPR55 increases neural stem cell proliferation and promotes early adult hippocampal neurogenesis.
Volume: 175
Issue: 16
Pages: 3407-3421
Publication
First Author: Romero-Zerbo SY
Year: 2011
Journal: J Endocrinol
Title: A role for the putative cannabinoid receptor GPR55 in the islets of Langerhans.
Volume: 211
Issue: 2
Pages: 177-85
Publication
First Author: Puhl SL
Year: 2021
Journal: Sci Rep
Title: Haematopoietic and cardiac GPR55 synchronize post-myocardial infarction remodelling.
Volume: 11
Issue: 1
Pages: 14385
Publication
First Author: Hurst K
Year: 2017
Journal: Hippocampus
Title: A putative lysophosphatidylinositol receptor GPR55 modulates hippocampal synaptic plasticity.
Volume: 27
Issue: 9
Pages: 985-998
Publication
First Author: Stančić A
Year: 2015
Journal: Neurogastroenterol Motil
Title: The GPR55 antagonist CID16020046 protects against intestinal inflammation.
Volume: 27
Issue: 10
Pages: 1432-45
Publication  
First Author: Hill JD
Year: 2019
Journal: Brain Behav Immun
Title: Activation of GPR55 induces neuroprotection of hippocampal neurogenesis and immune responses of neural stem cells following chronic, systemic inflammation.
Volume: 76
Pages: 165-181
Gene
Type: gene
Organism: human
Publication  
First Author: Li K
Year: 2013
Journal: Neuropharmacology
Title: A role for O-1602 and G protein-coupled receptor GPR55 in the control of colonic motility in mice.
Volume: 71
Pages: 255-63
Publication
First Author: Sylantyev S
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Cannabinoid- and lysophosphatidylinositol-sensitive receptor GPR55 boosts neurotransmitter release at central synapses.
Volume: 110
Issue: 13
Pages: 5193-8
Publication
First Author: Lipina C
Year: 2019
Journal: FASEB J
Title: GPR55 deficiency is associated with increased adiposity and impaired insulin signaling in peripheral metabolic tissues.
Volume: 33
Issue: 1
Pages: 1299-1312
Publication
First Author: Pérez-Gómez E
Year: 2013
Journal: Oncogene
Title: The orphan receptor GPR55 drives skin carcinogenesis and is upregulated in human squamous cell carcinomas.
Volume: 32
Issue: 20
Pages: 2534-42
Publication  
First Author: Ono T
Year: 2023
Journal: Brain Behav Immun
Title: GPR55 contributes to neutrophil recruitment and mechanical pain induction after spinal cord compression in mice.
Volume: 110
Pages: 276-287
Publication
First Author: Walsh SK
Year: 2014
Journal: PLoS One
Title: GPR55 deletion in mice leads to age-related ventricular dysfunction and impaired adrenoceptor-mediated inotropic responses.
Volume: 9
Issue: 9
Pages: e108999
Publication
First Author: Bjursell M
Year: 2016
Journal: PLoS One
Title: Deletion of Gpr55 Results in Subtle Effects on Energy Metabolism, Motor Activity and Thermal Pain Sensation.
Volume: 11
Issue: 12
Pages: e0167965
Publication
First Author: Ferro R
Year: 2018
Journal: Oncogene
Title: GPR55 signalling promotes proliferation of pancreatic cancer cells and tumour growth in mice, and its inhibition increases effects of gemcitabine.
Volume: 37
Issue: 49
Pages: 6368-6382
Publication
First Author: Hasenoehrl C
Year: 2018
Journal: Int J Cancer
Title: G protein-coupled receptor GPR55 promotes colorectal cancer and has opposing effects to cannabinoid receptor 1.
Volume: 142
Issue: 1
Pages: 121-132
Publication  
First Author: Guillamat-Prats R
Year: 2022
Journal: Nat Cardiovasc Res
Title: GPR55 in B cells limits atherosclerosis development and regulates plasma cell maturation.
Volume: 1
Pages: 1056-1071
Publication
First Author: Johns DG
Year: 2007
Journal: Br J Pharmacol
Title: The novel endocannabinoid receptor GPR55 is activated by atypical cannabinoids but does not mediate their vasodilator effects.
Volume: 152
Issue: 5
Pages: 825-31
GXD Expression      
Probe: MGI:6174326
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689419
Stage: TS19
Assay Id: MGI:6190430
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Gpr55
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:6174326
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:6190430
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Gpr55
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:6174326
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689424
Stage: TS24
Assay Id: MGI:6190430
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Gpr55
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:6174326
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:6190430
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Gpr55
Detected: false
Specimen Num: 4
GXD Expression      
Probe: MGI:6174326
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6190430
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Gpr55
Detected: false
Specimen Num: 5
GXD Expression      
Probe: MGI:6174326
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6190430
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Gpr55
Detected: false
Specimen Num: 6
GXD Expression      
Probe: MGI:6174326
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6190430
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Gpr55
Detected: false
Specimen Num: 7
Publication
First Author: Anderson LL
Year: 2023
Journal: PLoS One
Title: Heterozygous deletion of Gpr55 does not affect a hyperthermia-induced seizure, spontaneous seizures or survival in the Scn1a+/- mouse model of Dravet syndrome.
Volume: 18
Issue: 1
Pages: e0280842
Publication
First Author: McHugh D
Year: 2012
Journal: Br J Pharmacol
Title: Δ(9) -Tetrahydrocannabinol and N-arachidonyl glycine are full agonists at GPR18 receptors and induce migration in human endometrial HEC-1B cells.
Volume: 165
Issue: 8
Pages: 2414-24
Publication  
First Author: McHugh D
Year: 2010
Journal: BMC Neurosci
Title: N-arachidonoyl glycine, an abundant endogenous lipid, potently drives directed cellular migration through GPR18, the putative abnormal cannabidiol receptor.
Volume: 11
Pages: 44
Publication
First Author: Pertwee RG
Year: 2007
Journal: Br J Pharmacol
Title: GPR55: a new member of the cannabinoid receptor clan?
Volume: 152
Issue: 7
Pages: 984-6
Publication
First Author: Izzo AA
Year: 2010
Journal: Pharmacol Ther
Title: Cannabinoids and the gut: new developments and emerging concepts.
Volume: 126
Issue: 1
Pages: 21-38
Publication
First Author: Brown AJ
Year: 2007
Journal: Br J Pharmacol
Title: Novel cannabinoid receptors.
Volume: 152
Issue: 5
Pages: 567-75
Publication
First Author: Pertwee RG
Year: 2010
Journal: Pharmacol Rev
Title: International Union of Basic and Clinical Pharmacology. LXXIX. Cannabinoid receptors and their ligands: beyond CB₁ and CB₂.
Volume: 62
Issue: 4
Pages: 588-631
Protein
Organism: Mus musculus/domesticus
Length: 327  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 327  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 327  
Fragment?: false
Publication
First Author: Wu CS
Year: 2013
Journal: PLoS One
Title: GPR55, a G-protein coupled receptor for lysophosphatidylinositol, plays a role in motor coordination.
Volume: 8
Issue: 4
Pages: e60314
Publication
First Author: Ruz-Maldonado I
Year: 2020
Journal: Cell Mol Life Sci
Title: The cannabinoid ligands SR141716A and AM251 enhance human and mouse islet function via GPR55-independent signalling.
Volume: 77
Issue: 22
Pages: 4709-4723
Publication
First Author: Meadows A
Year: 2016
Journal: Int J Obes (Lond)
Title: Deletion of G-protein-coupled receptor 55 promotes obesity by reducing physical activity.
Volume: 40
Issue: 3
Pages: 417-24
Publication
First Author: Hawken ER
Year: 2019
Journal: Neuropsychopharmacology
Title: A novel GPR55-mediated satiety signal in the oval Bed Nucleus of the Stria Terminalis.
Volume: 44
Issue: 7
Pages: 1274-1283
Publication
First Author: Schicho R
Year: 2011
Journal: Inflamm Bowel Dis
Title: The atypical cannabinoid O-1602 protects against experimental colitis and inhibits neutrophil recruitment.
Volume: 17
Issue: 8
Pages: 1651-64
Publication  
First Author: Austrich-Olivares A
Year: 2022
Journal: Pharmaceuticals (Basel)
Title: Cannabinoid CB1 Receptor Involvement in the Actions of CBD on Anxiety and Coping Behaviors in Mice.
Volume: 15
Issue: 4
Publication
First Author: Guy AT
Year: 2015
Journal: Science
Title: NEURONAL DEVELOPMENT. Glycerophospholipid regulation of modality-specific sensory axon guidance in the spinal cord.
Volume: 349
Issue: 6251
Pages: 974-7
Publication
First Author: Sisay S
Year: 2013
Journal: PLoS One
Title: Genetic background can result in a marked or minimal effect of gene knockout (GPR55 and CB2 receptor) in experimental autoimmune encephalomyelitis models of multiple sclerosis.
Volume: 8
Issue: 10
Pages: e76907
Publication
First Author: Rosenberg EC
Year: 2023
Journal: Neuron
Title: Cannabidiol modulates excitatory-inhibitory ratio to counter hippocampal hyperactivity.
Volume: 111
Issue: 8
Pages: 1282-1300.e8
Publication
First Author: Zhai K
Year: 2020
Journal: Eur J Immunol
Title: IL-10 promotes malignant pleural effusion by regulating TH 1 response via an miR-7116-5p/GPR55/ERK pathway in mice.
Volume: 50
Issue: 11
Pages: 1798-1809
Publication
First Author: Grill M
Year: 2019
Journal: Histochem Cell Biol
Title: Cellular localization and regulation of receptors and enzymes of the endocannabinoid system in intestinal and systemic inflammation.
Volume: 151
Issue: 1
Pages: 5-20
Publication
First Author: Wu CS
Year: 2010
Journal: Eur J Neurosci
Title: Requirement of cannabinoid CB(1) receptors in cortical pyramidal neurons for appropriate development of corticothalamic and thalamocortical projections.
Volume: 32
Issue: 5
Pages: 693-706
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Toomey NL
Year: 2001
Journal: Oncogene
Title: Induction of a TRAIL-mediated suicide program by interferon alpha in primary effusion lymphoma.
Volume: 20
Issue: 48
Pages: 7029-40
GXD Expression    
Probe: MGI:6388712
Assay Type: Western blot
Annotation Date: 2020-02-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754422
Stage: TS22
Assay Id: MGI:6388719
Age: embryonic day 14.0-15.0
Image: 2
Specimen Label: E14/15
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6388712
Assay Type: Western blot
Annotation Date: 2020-02-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754423
Stage: TS23
Assay Id: MGI:6388719
Age: embryonic day 14.0-15.0
Image: 2
Specimen Label: E14/15
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6388712
Assay Type: Western blot
Annotation Date: 2020-02-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754424
Stage: TS24
Assay Id: MGI:6388719
Age: embryonic day 16.0-17.0
Image: 2
Specimen Label: E16/17
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6388712
Assay Type: Western blot
Annotation Date: 2020-02-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754425
Stage: TS25
Assay Id: MGI:6388719
Age: embryonic day 16.0-17.0
Image: 2
Specimen Label: E16/17
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6388712
Assay Type: Western blot
Annotation Date: 2020-02-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754426
Stage: TS26
Assay Id: MGI:6388719
Age: embryonic day 18.0-19.0
Image: 2
Specimen Label: E18/19
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6388712
Assay Type: Western blot
Annotation Date: 2020-02-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754427
Stage: TS27
Assay Id: MGI:6388719
Age: postnatal day 1
Image: 2
Specimen Label: P1
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6388712
Assay Type: Western blot
Annotation Date: 2020-02-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754427
Stage: TS27
Assay Id: MGI:6388719
Age: postnatal day 3
Image: 2
Specimen Label: P3
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6388712
Assay Type: Western blot
Annotation Date: 2020-02-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716823
Stage: TS23
Assay Id: MGI:6388718
Age: embryonic day 14.0-15.0
Image: 2
Specimen Label: E14/15
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6388712
Assay Type: Western blot
Annotation Date: 2020-02-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716822
Stage: TS22
Assay Id: MGI:6388718
Age: embryonic day 14.0-15.0
Image: 2
Specimen Label: E14/15
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6388712
Assay Type: Western blot
Annotation Date: 2020-02-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716825
Stage: TS25
Assay Id: MGI:6388718
Age: embryonic day 16.0-17.0
Image: 2
Specimen Label: E16/17
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6388712
Assay Type: Western blot
Annotation Date: 2020-02-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716824
Stage: TS24
Assay Id: MGI:6388718
Age: embryonic day 16.0-17.0
Image: 2
Specimen Label: E16/17
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6388712
Assay Type: Western blot
Annotation Date: 2020-02-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716826
Stage: TS26
Assay Id: MGI:6388718
Age: embryonic day 18.0-19.0
Image: 2
Specimen Label: E18/19
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6388712
Assay Type: Western blot
Annotation Date: 2020-02-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716827
Stage: TS27
Assay Id: MGI:6388718
Age: postnatal day 1
Image: 2
Specimen Label: P1
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6388712
Assay Type: Western blot
Annotation Date: 2020-02-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716827
Stage: TS27
Assay Id: MGI:6388718
Age: postnatal day 3
Image: 2
Specimen Label: P3
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6388712
Assay Type: Western blot
Annotation Date: 2020-02-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716823
Stage: TS23
Assay Id: MGI:6388720
Age: embryonic day 14.0-15.0
Image: 2
Specimen Label: +/+
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6388712
Assay Type: Western blot
Annotation Date: 2020-02-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716822
Stage: TS22
Assay Id: MGI:6388720
Age: embryonic day 14.0-15.0
Image: 2
Specimen Label: +/+
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6388712
Assay Type: Western blot
Annotation Date: 2020-02-05
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1716823
Stage: TS23
Assay Id: MGI:6388720
Age: embryonic day 14.0-15.0
Image: 2
Specimen Label: -/-
Detected: false
Specimen Num: 2