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Search results 1 to 100 out of 900 for Hdac2

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Hits by Pathway

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Hits by Category

Type Details Score
Gene
3066 | HDAC2
Type: gene
Organism: human
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Gene
407223 | HDAC2
Type: gene
Organism: cattle
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Gene
395635 | HDAC2
Type: gene
Organism: chicken
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Gene
694662 | HDAC2
Type: gene
Organism: macaque, rhesus
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Gene
447995 | hdac2
Type: gene
Organism: frog, western clawed
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Gene
84577 | Hdac2
Type: gene
Organism: rat
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Gene
475035 | HDAC2
Type: gene
Organism: dog, domestic
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Gene
462950 | HDAC2
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:1097691 | Hdac2
Type: protein_coding_gene
Organism: mouse, laboratory
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GXD Expression
GXD Expression
Probe: MGI:6194047
Assay Type: Immunohistochemistry
Annotation Date: 2018-08-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3102528
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6194075
Age: postnatal adult
Image: 2 HDAC2
Note: Expression co-localizes with Hdac1 mainly throughout the nucleoplasm.
Specimen Label: 2 HDAC2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:6194047
Assay Type: Immunohistochemistry
Annotation Date: 2018-08-10
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:318643
Pattern: Regionally restricted
Stage: TS03
Assay Id: MGI:6194073
Age: embryonic day 2.0
Image: 1A HDAC2 4-Cell
Note: Progressive decrease in intensity of nuclear expression commencing at the 2-cell stage.
Specimen Label: 1A HDAC2 4-Cell
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:6194047
Assay Type: Immunohistochemistry
Annotation Date: 2018-08-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160331
Pattern: Regionally restricted
Stage: TS01
Assay Id: MGI:6194073
Age: embryonic day 0.5
Image: 1A HDAC2 1-Cell
Note: Expression in pronucleus/nucleus.
Specimen Label: 1A HDAC2 1-Cell
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:6502585
Assay Type: RNA in situ
Annotation Date: 2021-01-28
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1859021
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:6502633
Age: embryonic day 13.5
Image: 4A Hdac2 WT
Note: Strongest expression in retinal ganglion cell layer.
Specimen Label: 4A Hdac2 WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:6502585
Assay Type: RNA in situ
Annotation Date: 2021-01-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1859021
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:6502633
Age: embryonic day 13.5
Image: 4A Hdac2 Vax2-/-
Note: Expression lost specifically in the ventral retina.
Specimen Label: 4A Hdac2 Vax2-/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:6194047
Assay Type: Immunohistochemistry
Annotation Date: 2018-08-10
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:318653
Pattern: Regionally restricted
Stage: TS03
Assay Id: MGI:6194073
Age: embryonic day 2.5
Image: 1A HDAC2 8-Cell
Note: Progressive decrease in intensity of nuclear expression commencing at the 2-cell stage.
Specimen Label: 1A HDAC2 8-Cell
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:6194047
Assay Type: Immunohistochemistry
Annotation Date: 2018-08-10
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:360354
Pattern: Not Specified
Stage: TS04
Assay Id: MGI:6194073
Age: embryonic day 3.5
Image: 1A HDAC2 Blast
Note: Progressive decrease in intensity of nuclear expression commencing at the 2-cell stage.
Specimen Label: 1A HDAC2 Blast
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:6194047
Assay Type: Immunohistochemistry
Annotation Date: 2018-08-10
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:160404
Pattern: Not Specified
Stage: TS04
Assay Id: MGI:6194073
Age: embryonic day 3.0
Image: 1A HDAC2 Morula
Note: Progressive decrease in intensity of nuclear expression commencing at the 2-cell stage.
Specimen Label: 1A HDAC2 Morula
Specimen Num: 6
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GXD Expression
GXD Expression
Probe: MGI:6194047
Assay Type: Immunohistochemistry
Annotation Date: 2018-08-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3102528
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6194073
Age: postnatal adult
Image: 1A HDAC2 Oocyte
Note: Expression concentrated in nucleus.
Specimen Label: 1A HDAC2 Oocyte
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:6194047
Assay Type: Immunohistochemistry
Annotation Date: 2018-08-10
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:160362
Pattern: Regionally restricted
Stage: TS02
Assay Id: MGI:6194073
Age: embryonic day 1.0
Image: 1A HDAC2 2-Cell
Note: Progressive decrease in intensity of nuclear expression commencing at the 2-cell stage.
Specimen Label: 1A HDAC2 2-Cell
Detected: true
Specimen Num: 3
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Gene
101927768 | HDAC2-AS2
Type: gene
Organism: human
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Publication
34903606 | J:321263
First Author: Krauß L
Year: 2022
Journal: Cancer Res
Title: HDAC2 Facilitates Pancreatic Cancer Metastasis.
Volume: 82
Issue: 4
Pages: 695-707
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Publication
19424149 | J:148391
First Author: Guan JS
Year: 2009
Journal: Nature
Title: HDAC2 negatively regulates memory formation and synaptic plasticity.
Volume: 459
Issue: 7243
Pages: 55-60
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GXD Expression
GXD Expression
     
Probe: MGI:5762592
Assay Type: RT-PCR
Annotation Date: 2016-04-20
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1754420
Stage: TS20
Assay Id: MGI:5762707
Age: embryonic day 12.5
Image: S9
Specimen Label: HDAC2 E12
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5762592
Assay Type: RT-PCR
Annotation Date: 2016-04-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754423
Stage: TS23
Assay Id: MGI:5762707
Age: embryonic day 15.5
Image: S9
Specimen Label: HDAC2 E15
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5762592
Assay Type: RT-PCR
Annotation Date: 2016-04-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754426
Stage: TS26
Assay Id: MGI:5762707
Age: embryonic day 18.5
Image: S9
Specimen Label: HDAC2 E18
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:6164190
Assay Type: Western blot
Annotation Date: 2022-06-10
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610524
Stage: TS24
Assay Id: MGI:7284712
Age: embryonic day 16.5
Specimen Label: Hdac2 KO
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:3621873
Assay Type: RNA in situ
Annotation Date: 2006-05-10
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3287221
Stage: TS21
Assay Id: MGI:3621875
Age: embryonic day 13.0
Specimen Label: 1B HDAC2
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:3621873
Assay Type: RNA in situ
Annotation Date: 2006-05-10
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3287223
Stage: TS23
Assay Id: MGI:3621875
Age: embryonic day 15.0
Specimen Label: 1B HDAC2
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:3621732
Assay Type: Immunohistochemistry
Annotation Date: 2006-05-10
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3287221
Stage: TS21
Assay Id: MGI:3621877
Age: embryonic day 13.0
Specimen Label: 1C HDAC2
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:3621732
Assay Type: Immunohistochemistry
Annotation Date: 2006-05-10
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3287225
Stage: TS25
Assay Id: MGI:3621877
Age: embryonic day 17.0
Specimen Label: 1C HDAC2
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:3051325
Assay Type: Immunohistochemistry
Annotation Date: 2007-01-04
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3692436
Age: embryonic day 14.5
Specimen Label: 7A, HDAC2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3692734
Assay Type: Immunohistochemistry
Annotation Date: 2007-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3692735
Age: embryonic day 14.5
Note: Expression is in postmitotic neurons located in the cortical plate region.
Specimen Label: 7B HDAC2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:3051325
Assay Type: Immunohistochemistry
Annotation Date: 2007-01-04
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3271222
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3692436
Age: embryonic day 14.5
Specimen Label: 7A, HDAC2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3621873
Assay Type: RNA in situ
Annotation Date: 2006-05-10
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3287421
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:3621875
Age: embryonic day 13.0
Note: Expression is in outer serosal cells.
Specimen Label: 1B HDAC2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3621873
Assay Type: RNA in situ
Annotation Date: 2006-05-10
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:3287423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:3621875
Age: embryonic day 15.0
Note: Expression is in outer serosal cells.
Specimen Label: 1B HDAC2
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:3621732
Assay Type: Immunohistochemistry
Annotation Date: 2006-05-10
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3287421
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:3621877
Age: embryonic day 13.0
Note: Expression is in outer serosal cells.
Specimen Label: 1C HDAC2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3621732
Assay Type: Immunohistochemistry
Annotation Date: 2006-05-10
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:3287425
Pattern: Regionally restricted
Stage: TS25
Assay Id: MGI:3621877
Age: embryonic day 17.0
Note: Expression is in outer serosal cells.
Specimen Label: 1C HDAC2
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:3051325
Assay Type: Immunohistochemistry
Annotation Date: 2007-01-04
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3692436
Age: embryonic day 14.5
Specimen Label: 7A, HDAC2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3621873
Assay Type: RNA in situ
Annotation Date: 2006-05-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3287321
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3621875
Age: embryonic day 13.0
Note: Expression is in the periluminal epithelium.
Specimen Label: 1B HDAC2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3621873
Assay Type: RNA in situ
Annotation Date: 2006-05-10
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3287323
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:3621875
Age: embryonic day 15.0
Note: Expression is in the periluminal epithelium.
Specimen Label: 1B HDAC2
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:3621732
Assay Type: Immunohistochemistry
Annotation Date: 2006-05-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3287321
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3621877
Age: embryonic day 13.0
Note: Expression is in the periluminal epithelium.
Specimen Label: 1C HDAC2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3621732
Assay Type: Immunohistochemistry
Annotation Date: 2006-05-10
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3287325
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:3621877
Age: embryonic day 17.0
Note: Expression is in the periluminal epithelium.
Specimen Label: 1C HDAC2
Detected: true
Specimen Num: 2
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Publication
23696608 | J:214041
First Author: Fan J
Year: 2013
Journal: Invest Ophthalmol Vis Sci
Title: Inhibition of HDAC2 protects the retina from ischemic injury.
Volume: 54
Issue: 6
Pages: 4072-80
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Publication
21094147 | J:167047
First Author: Adenuga D
Year: 2010
Journal: Biochem Biophys Res Commun
Title: Nrf2 deficiency influences susceptibility to steroid resistance via HDAC2 reduction.
Volume: 403
Issue: 3-4
Pages: 452-6
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Publication
10888872 | J:81304
First Author: Rountree MR
Year: 2000
Journal: Nat Genet
Title: DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci.
Volume: 25
Issue: 3
Pages: 269-77
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Publication
25648995 | J:220991
First Author: Zimberlin CD
Year: 2015
Journal: FASEB J
Title: HDAC1 and HDAC2 collectively regulate intestinal stem cell homeostasis.
Volume: 29
Issue: 5
Pages: 2070-80
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Publication
23436026 | J:317798
First Author: Yoo JY
Year: 2013
Journal: Cerebellum
Title: The expression of HDAC1 and HDAC2 during cerebellar cortical development.
Volume: 12
Issue: 4
Pages: 534-46
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Publication
32415988 | J:304180
First Author: Lin YH
Year: 2020
Journal: J Neurochem
Title: HDAC2 (Histone deacetylase 2): A critical factor in environmental enrichment-mediated stroke recovery.
Volume: 155
Issue: 6
Pages: 679-696
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Publication
22864611 | J:191594
First Author: Kurita M
Year: 2012
Journal: Nat Neurosci
Title: HDAC2 regulates atypical antipsychotic responses through the modulation of mGlu2 promoter activity.
Volume: 15
Issue: 9
Pages: 1245-54
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Publication
28783139 | J:258028
First Author: Ibi D
Year: 2017
Journal: Nat Neurosci
Title: Antipsychotic-induced Hdac2 transcription via NF-κB leads to synaptic and cognitive side effects.
Volume: 20
Issue: 9
Pages: 1247-1259
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Publication
25609639 | J:218977
First Author: Peng S
Year: 2015
Journal: J Neurosci
Title: HDAC2 selectively regulates FOXO3a-mediated gene transcription during oxidative stress-induced neuronal cell death.
Volume: 35
Issue: 3
Pages: 1250-9
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Publication
21423190 | J:172298
First Author: Jacob C
Year: 2011
Journal: Nat Neurosci
Title: HDAC1 and HDAC2 control the transcriptional program of myelination and the survival of Schwann cells.
Volume: 14
Issue: 4
Pages: 429-36
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GXD Expression
GXD Expression
 
Probe: MGI:6164190
Assay Type: Immunohistochemistry
Annotation Date: 2022-06-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610527
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:7284684
Age: postnatal day 0
Note: Expression by many, but not all, cardiomyocytes. Co-localized with Hopx reporter expression.
Specimen Label: 1A Hdac2 IHC
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:6164190
Assay Type: Immunohistochemistry
Annotation Date: 2022-06-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610527
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:7284684
Age: postnatal day 0
Note: Expression by many, but not all, cardiomyocytes. Co-localized with Hopx reporter expression.
Specimen Label: 1A Hdac2 IHC
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:6164190
Assay Type: Immunohistochemistry
Annotation Date: 2022-06-10
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:7284685
Age: postnatal day 0
Specimen Label: 1D Hdac2 KO Hdac2
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6164190
Assay Type: Immunohistochemistry
Annotation Date: 2022-06-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610527
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7284685
Age: postnatal day 0
Specimen Label: 1D Hopx KO Hdac2
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:6164190
Assay Type: Immunohistochemistry
Annotation Date: 2022-06-10
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:7284685
Age: postnatal day 0
Specimen Label: 1D DKO Hdac2
Detected: false
Specimen Num: 4
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Publication
19503085 | J:152576
First Author: Ye F
Year: 2009
Journal: Nat Neurosci
Title: HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the beta-catenin-TCF interaction.
Volume: 12
Issue: 7
Pages: 829-38
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Publication
26287468 | J:225970
First Author: Zhang Q
Year: 2015
Journal: Nature
Title: Tet2 is required to resolve inflammation by recruiting Hdac2 to specifically repress IL-6.
Volume: 525
Issue: 7569
Pages: 389-393
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Publication
30709655 | J:278287
First Author: Tang T
Year: 2019
Journal: Neuron
Title: HDAC1 and HDAC2 Regulate Intermediate Progenitor Positioning to Safeguard Neocortical Development.
Volume: 101
Issue: 6
Pages: 1117-1133.e5
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Publication
20571512 | J:197818
First Author: Wilting RH
Year: 2010
Journal: EMBO J
Title: Overlapping functions of Hdac1 and Hdac2 in cell cycle regulation and haematopoiesis.
Volume: 29
Issue: 15
Pages: 2586-97
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Publication
27721407 | J:241090
First Author: Stojanovic N
Year: 2017
Journal: Oncogene
Title: HDAC1 and HDAC2 integrate the expression of p53 mutants in pancreatic cancer.
Volume: 36
Issue: 13
Pages: 1804-1815
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Publication
28793257 | J:255259
First Author: Yamakawa H
Year: 2017
Journal: Cell Rep
Title: The Transcription Factor Sp3 Cooperates with HDAC2 to Regulate Synaptic Function and Plasticity in Neurons.
Volume: 20
Issue: 6
Pages: 1319-1334
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Publication
17322895 | J:121697
First Author: Trivedi CM
Year: 2007
Journal: Nat Med
Title: Hdac2 regulates the cardiac hypertrophic response by modulating Gsk3 beta activity.
Volume: 13
Issue: 3
Pages: 324-31
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Publication
30926862 | J:276092
First Author: Gonneaud A
Year: 2019
Journal: Sci Rep
Title: HDAC1 and HDAC2 independently regulate common and specific intrinsic responses in murine enteroids.
Volume: 9
Issue: 1
Pages: 5363
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Publication
30407865 | J:268752
First Author: Lai T
Year: 2019
Journal: Am J Physiol Lung Cell Mol Physiol
Title: HDAC2 attenuates airway inflammation by suppressing IL-17A production in HDM-challenged mice.
Volume: 316
Issue: 1
Pages: L269-L279
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Publication
26174178 | J:313143
First Author: Gonneaud A
Year: 2016
Journal: J Cell Physiol
Title: Distinct Roles for Intestinal Epithelial Cell-Specific Hdac1 and Hdac2 in the Regulation of Murine Intestinal Homeostasis.
Volume: 231
Issue: 2
Pages: 436-48
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Publication
23359715 | J:194321
First Author: Nott A
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: S-nitrosylation of HDAC2 regulates the expression of the chromatin-remodeling factor Brm during radial neuron migration.
Volume: 110
Issue: 8
Pages: 3113-8
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Publication
33849645 | J:304972
First Author: Datta M
Year: 2021
Journal: BMC Res Notes
Title: Hdac1 and Hdac2 are essential for physiological maturation of a Cx3cr1 expressing subset of T-lymphocytes.
Volume: 14
Issue: 1
Pages: 135
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Publication
24040068 | J:207554
First Author: Turgeon N
Year: 2013
Journal: PLoS One
Title: HDAC1 and HDAC2 restrain the intestinal inflammatory response by regulating intestinal epithelial cell differentiation.
Volume: 8
Issue: 9
Pages: e73785
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•
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•
Publication
20833366 | J:164279
First Author: Trivedi CM
Year: 2010
Journal: Dev Cell
Title: Hopx and Hdac2 interact to modulate Gata4 acetylation and embryonic cardiac myocyte proliferation.
Volume: 19
Issue: 3
Pages: 450-9
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Publication
33907245 | J:313782
First Author: Aufhauser DD Jr
Year: 2021
Journal: Sci Rep
Title: HDAC2 targeting stabilizes the CoREST complex in renal tubular cells and protects against renal ischemia/reperfusion injury.
Volume: 11
Issue: 1
Pages: 9018
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•
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•
Publication
19041327 | J:149270
First Author: Kong X
Year: 2009
Journal: J Mol Cell Cardiol
Title: HDAC2 deacetylates class II transactivator and suppresses its activity in macrophages and smooth muscle cells.
Volume: 46
Issue: 3
Pages: 292-9
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•
•
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•
Publication
21093383 | J:168590
First Author: LeBoeuf M
Year: 2010
Journal: Dev Cell
Title: Hdac1 and Hdac2 act redundantly to control p63 and p53 functions in epidermal progenitor cells.
Volume: 19
Issue: 6
Pages: 807-18
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•
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Publication
37563109 | J:339589
First Author: Sibony-Benyamini H
Year: 2023
Journal: Nat Commun
Title: Hdac1 and Hdac2 regulate the quiescent state and survival of hair-follicle mesenchymal niche.
Volume: 14
Issue: 1
Pages: 4820
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Publication
24240174 | J:206161
First Author: Winter M
Year: 2013
Journal: EMBO J
Title: Divergent roles of HDAC1 and HDAC2 in the regulation of epidermal development and tumorigenesis.
Volume: 32
Issue: 24
Pages: 3176-91
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Publication
22933299 | J:189969
First Author: Hsing CH
Year: 2012
Journal: Am J Physiol Renal Physiol
Title: α2-Adrenoceptor agonist dexmedetomidine protects septic acute kidney injury through increasing BMP-7 and inhibiting HDAC2 and HDAC5.
Volume: 303
Issue: 10
Pages: F1443-53
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Publication
26129908 | J:318789
 
First Author: Lebrun-Julien F
Year: 2015
Journal: ASN Neuro
Title: Combined HDAC1 and HDAC2 Depletion Promotes Retinal Ganglion Cell Survival After Injury Through Reduction of p53 Target Gene Expression.
Volume: 7
Issue: 3
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Publication
30358442 | J:272974
First Author: Bin Y
Year: 2019
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Theophylline inhibits cigarette smoke-induced inflammation in skeletal muscle by upregulating HDAC2 expression and decreasing NF-κB activation.
Volume: 316
Issue: 1
Pages: L197-L205
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Publication
24449838 | J:208338
First Author: Hagelkruys A
Year: 2014
Journal: Development
Title: A single allele of Hdac2 but not Hdac1 is sufficient for normal mouse brain development in the absence of its paralog.
Volume: 141
Issue: 3
Pages: 604-616
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Publication
24525021 | J:210274
First Author: Turgeon N
Year: 2014
Journal: Am J Physiol Gastrointest Liver Physiol
Title: The acetylome regulators Hdac1 and Hdac2 differently modulate intestinal epithelial cell dependent homeostatic responses in experimental colitis.
Volume: 306
Issue: 7
Pages: G594-605
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Publication
19047631 | J:142085
First Author: Colussi C
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: HDAC2 blockade by nitric oxide and histone deacetylase inhibitors reveals a common target in Duchenne muscular dystrophy treatment.
Volume: 105
Issue: 49
Pages: 19183-7
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Publication
22223663 | J:181953
First Author: Ma P
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Compensatory functions of histone deacetylase 1 (HDAC1) and HDAC2 regulate transcription and apoptosis during mouse oocyte development.
Volume: 109
Issue: 8
Pages: E481-9
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Publication
24760871 | J:210607
First Author: Jacob C
Year: 2014
Journal: J Neurosci
Title: HDAC1 and HDAC2 control the specification of neural crest cells into peripheral glia.
Volume: 34
Issue: 17
Pages: 6112-22
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Publication
26721795 | J:324497
First Author: Torres OV
Year: 2016
Journal: Neurotox Res
Title: An Acute Methamphetamine Injection Downregulates the Expression of Several Histone Deacetylases (HDACs) in the Mouse Nucleus Accumbens: Potential Regulatory Role of HDAC2 Expression.
Volume: 30
Issue: 1
Pages: 32-40
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GXD Expression
GXD Expression
   
Probe: MGI:6174734
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6190488
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Hdac2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6174734
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6190488
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Hdac2
Detected: true
Specimen Num: 2
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•
GXD Expression
GXD Expression
   
Probe: MGI:6174734
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6190488
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Hdac2
Detected: true
Specimen Num: 3
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•
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•
GXD Expression
GXD Expression
   
Probe: MGI:6174734
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6190488
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Hdac2
Detected: true
Specimen Num: 4
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•
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•
GXD Expression
GXD Expression
   
Probe: MGI:6174734
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190488
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Hdac2
Detected: true
Specimen Num: 5
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•
GXD Expression
GXD Expression
   
Probe: MGI:6174734
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190488
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Hdac2
Detected: true
Specimen Num: 6
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•
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•
GXD Expression
GXD Expression
   
Probe: MGI:6174734
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190488
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Hdac2
Detected: true
Specimen Num: 7
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Publication
34077868 | J:321285
 
First Author: Wang L
Year: 2021
Journal: Atherosclerosis
Title: Inhibition of myeloid HDAC2 upregulates glutaredoxin 1 expression, improves protein thiol redox state and protects against high-calorie diet-induced monocyte dysfunction and atherosclerosis.
Volume: 328
Pages: 23-32
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Publication
22811558 | J:212642
First Author: Salmon M
Year: 2012
Journal: Circ Res
Title: Cooperative binding of KLF4, pELK-1, and HDAC2 to a G/C repressor element in the SM22α promoter mediates transcriptional silencing during SMC phenotypic switching in vivo.
Volume: 111
Issue: 6
Pages: 685-96
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GXD Expression
GXD Expression
Probe: MGI:6360257
Assay Type: Immunohistochemistry
Annotation Date: 2019-09-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760625
Pattern: Regionally restricted
Stage: TS25
Assay Id: MGI:6360288
Age: embryonic day 17.0
Image: 6G
Note: Co-expression in many Dnmt3a-expressing cells. Most basal cells express Hdac2 exclusively.
Specimen Label: 6G
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
Probe: MGI:6360257
Assay Type: Immunohistochemistry
Annotation Date: 2019-09-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760628
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6360288
Age: postnatal day 5
Image: 6H
Note: Co-expression in many Dnmt3a-expressing cells. Most basal cells express Hdac2 exclusively.
Specimen Label: 6H
Detected: true
Specimen Num: 8
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Publication
18495085 | J:137916
First Author: Sun C
Year: 2008
Journal: Biochem Pharmacol
Title: Trichostatin A improves insulin stimulated glucose utilization and insulin signaling transduction through the repression of HDAC2.
Volume: 76
Issue: 1
Pages: 120-7
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Publication
26598605 | J:236141
First Author: Hagelkruys A
Year: 2015
Journal: Mol Cell Biol
Title: Essential Nonredundant Function of the Catalytic Activity of Histone Deacetylase 2 in Mouse Development.
Volume: 36
Issue: 3
Pages: 462-74
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Publication
29630406 | J:278939
First Author: Sundar IK
Year: 2018
Journal: FASEB J
Title: Genetic ablation of histone deacetylase 2 leads to lung cellular senescence and lymphoid follicle formation in COPD/emphysema.
Volume: 32
Issue: 9
Pages: 4955-4971
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Publication
30025863 | J:267033
 
First Author: de la Fuente Revenga M
Year: 2018
Journal: Neuroscience
Title: HDAC2-dependent Antipsychotic-like Effects of Chronic Treatment with the HDAC Inhibitor SAHA in Mice.
Volume: 388
Pages: 102-117
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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