| Type |
Details |
Score |
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, western clawed |
|
•
•
•
•
•
|
| Gene |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
dog, domestic |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chimpanzee |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
cattle |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chicken |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
zebrafish |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:8262966 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2025-11-24 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1796225 |
| Pattern: |
Not Specified |
| Stage: |
TS25 |
| Assay Id: |
MGI:8263046 |
| Age: |
embryonic day 17.5 |
| Image: |
1c WT HFM1 |
|
| Specimen Label: |
1c WT HFM1 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:8262966 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2025-11-24 |
| Strength: |
Absent |
| Sex: |
Female |
| Emaps: |
EMAPS:1796225 |
|
| Stage: |
TS25 |
| Assay Id: |
MGI:8263046 |
| Age: |
embryonic day 17.5 |
| Image: |
1c KO HFM1 |
| Note: |
Authors report complete deletion of expression. |
| Specimen Label: |
1c KO HFM1 |
| Detected: |
false |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang H |
| Year: |
2020 |
| Journal: |
Cell Death Dis |
| Title: |
Hfm1 participates in Golgi-associated spindle assembly and division in mouse oocyte meiosis. |
| Volume: |
11 |
| Issue: |
6 |
| Pages: |
490 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
He Y |
| Year: |
2024 |
| Journal: |
Cell Mol Life Sci |
| Title: |
HFM1 is essential for the germ cell intercellular bridge transport in primordial follicle formation in mice. |
| Volume: |
82 |
| Issue: |
1 |
| Pages: |
28 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Guiraldelli MF |
| Year: |
2013 |
| Journal: |
PLoS Genet |
| Title: |
Mouse HFM1/Mer3 is required for crossover formation and complete synapsis of homologous chromosomes during meiosis. |
| Volume: |
9 |
| Issue: |
3 |
| Pages: |
e1003383 |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus caroli |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus pahari |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus spretus |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:8262965 |
| Assay Type: |
Western blot |
| Annotation Date: |
2025-11-24 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1796223 |
|
| Stage: |
TS23 |
| Assay Id: |
MGI:8263031 |
| Age: |
embryonic day 15.5 |
| Image: |
1 |
|
| Specimen Label: |
E15.5 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:8262965 |
| Assay Type: |
Western blot |
| Annotation Date: |
2025-11-24 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1796225 |
|
| Stage: |
TS25 |
| Assay Id: |
MGI:8263031 |
| Age: |
embryonic day 17.5 |
| Image: |
1 |
|
| Specimen Label: |
E17.5 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:8262965 |
| Assay Type: |
Western blot |
| Annotation Date: |
2025-11-24 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1796227 |
|
| Stage: |
TS27 |
| Assay Id: |
MGI:8263031 |
| Age: |
postnatal day 1 |
| Image: |
1 |
|
| Specimen Label: |
P1 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:8262965 |
| Assay Type: |
Western blot |
| Annotation Date: |
2025-11-24 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1796227 |
|
| Stage: |
TS27 |
| Assay Id: |
MGI:8263031 |
| Age: |
postnatal day 3 |
| Image: |
1 |
|
| Specimen Label: |
P3 |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:8262965 |
| Assay Type: |
Western blot |
| Annotation Date: |
2025-11-24 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1796225 |
|
| Stage: |
TS25 |
| Assay Id: |
MGI:8263032 |
| Age: |
embryonic day 17.5 |
| Image: |
1 |
|
| Specimen Label: |
WT |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:8262965 |
| Assay Type: |
Western blot |
| Annotation Date: |
2025-11-24 |
| Strength: |
Absent |
| Sex: |
Female |
| Emaps: |
EMAPS:1796225 |
|
| Stage: |
TS25 |
| Assay Id: |
MGI:8263032 |
| Age: |
embryonic day 17.5 |
| Image: |
1 |
|
| Specimen Label: |
KO |
| Detected: |
false |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:8262965 |
| Assay Type: |
Western blot |
| Annotation Date: |
2025-11-24 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1796225 |
|
| Stage: |
TS25 |
| Assay Id: |
MGI:8263039 |
| Age: |
embryonic day 17.5 |
| Image: |
6 |
|
| Specimen Label: |
Input |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:8262965 |
| Assay Type: |
Western blot |
| Annotation Date: |
2025-11-24 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1796225 |
|
| Stage: |
TS25 |
| Assay Id: |
MGI:8263041 |
| Age: |
embryonic day 17.5 |
| Image: |
6 |
|
| Specimen Label: |
Input |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Rezaei M |
| Year: |
2024 |
| Journal: |
J Clin Invest |
| Title: |
Defects in meiosis I contribute to the genesis of androgenetic hydatidiform moles. |
| Volume: |
134 |
| Issue: |
22 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Previato de Almeida L |
| Year: |
2019 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Shugoshin protects centromere pairing and promotes segregation of nonexchange partner chromosomes in meiosis. |
| Volume: |
116 |
| Issue: |
19 |
| Pages: |
9417-9422 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Duroc Y |
| Year: |
2017 |
| Journal: |
Elife |
| Title: |
Concerted action of the MutL? heterodimer and Mer3 helicase regulates the global extent of meiotic gene conversion. |
| Volume: |
6 |
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lee CY |
| Year: |
2015 |
| Journal: |
Cell Rep |
| Title: |
Mechanism and regulation of rapid telomere prophase movements in mouse meiotic chromosomes. |
| Volume: |
11 |
| Issue: |
4 |
| Pages: |
551-63 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ito M |
| Year: |
2025 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Distinct and interdependent functions of three RING proteins regulate recombination during mammalian meiosis. |
| Volume: |
122 |
| Issue: |
2 |
| Pages: |
e2412961121 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ni L |
| Year: |
2016 |
| Journal: |
Mol Reprod Dev |
| Title: |
Multiple roles of FOXJ3 in spermatogenesis: A lesson from Foxj3 conditional knockout mouse models. |
| Volume: |
83 |
| Issue: |
12 |
| Pages: |
1060-1069 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2003 |
| Journal: |
Database Download |
| Title: |
Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
GOA curators, MGI curators |
| Year: |
2001 |
|
| Title: |
Gene Ontology annotation based on Enzyme Commission mapping |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
GO Central curators, GOA curators, Rhea curators |
| Year: |
2020 |
|
| Title: |
Automatic Gene Ontology annotation based on Rhea mapping |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wellcome Trust Sanger Institute |
| Year: |
2010 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zambrowicz BP |
| Year: |
2003 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
| Volume: |
100 |
| Issue: |
24 |
| Pages: |
14109-14 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Skarnes WC |
| Year: |
2011 |
| Journal: |
Nature |
| Title: |
A conditional knockout resource for the genome-wide study of mouse gene function. |
| Volume: |
474 |
| Issue: |
7351 |
| Pages: |
337-42 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
MGD Nomenclature Committee |
| Year: |
1995 |
|
| Title: |
Nomenclature Committee Use |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
| Year: |
2008 |
| Journal: |
Database Download |
| Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cyagen Biosciences Inc. |
| Year: |
2022 |
|
| Title: |
Cyagen Biosciences Website. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
GOA curators |
| Year: |
2016 |
|
| Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
| Year: |
2011 |
|
| Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2003 |
|
| Title: |
MGI Sequence Curation Reference |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
GemPharmatech |
| Year: |
2020 |
|
| Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
The Gene Ontology Consortium |
| Year: |
2010 |
|
| Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
DDB, FB, MGI, GOA, ZFIN curators |
| Year: |
2001 |
|
| Title: |
Gene Ontology annotation through association of InterPro records with GO terms |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
MGI Genome Annotation Group and UniGene Staff |
| Year: |
2015 |
| Journal: |
Database Download |
| Title: |
MGI-UniGene Interconnection Effort |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
| Year: |
2010 |
|
| Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
| Year: |
2000 |
| Journal: |
Database Release |
| Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Group |
| Year: |
2003 |
| Journal: |
Database Procedure |
| Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bairoch A |
| Year: |
1999 |
| Journal: |
Database Release |
| Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics |
| Year: |
2010 |
| Journal: |
Database Release |
| Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Allen Institute for Brain Science |
| Year: |
2004 |
| Journal: |
Allen Institute |
| Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1434
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| UniProt Feature |
| Begin: |
1 |
| Description: |
Probable ATP-dependent DNA helicase HFM1 |
| Type: |
chain |
| End: |
1434 |
|
•
•
•
•
•
|
| QTL |
| Type: |
QTL |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| DO Term |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ponting CP |
| Year: |
2000 |
| Journal: |
Biochem J |
| Title: |
Proteins of the endoplasmic-reticulum-associated degradation pathway: domain detection and function prediction. |
| Volume: |
351 Pt 2 |
| Issue: |
Pt 2 |
| Pages: |
527-35 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jermy AJ |
| Year: |
2006 |
| Journal: |
J Biol Chem |
| Title: |
The Brl domain in Sec63p is required for assembly of functional endoplasmic reticulum translocons. |
| Volume: |
281 |
| Issue: |
12 |
| Pages: |
7899-906 |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Domain |
| Description: |
This domain was named after the yeast Sec63 (or NPL1) (also known as the Brl domain) protein in which it was found. This protein is required for assembly of functional endoplasmic reticulum translocons [, ]. Other yeast proteins containing this domain include pre-mRNA splicing helicase BRR2, HFM1 protein and putative helicases. |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
626
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
760
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
760
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
516
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
428
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
2198
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
2136
 |
| Fragment?: |
false |
|
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•
•
•
•
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